VASODILATION AND INOTROPISM OF THE PHOSPHODIESTERASE INHIBITOR ENOXIMON
1991 | journal article; research paper. A publication with affiliation to the University of Göttingen.
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- Authors
- Holubarsch, Christian; Hasenfuß, Gerd ; Thierfelder, L.; Heiss, H.Wolfgang; Just, Hanjörg
- Abstract
- The comparison of two invasive studies using intravenous application of the phosphodiesterase enoximone demonstrated unchanged cardiac output in patients with dilated cardiomyopathy NYHA II-III, and increased cardiac output (from 3.22 +/- 1.15 to 5.04 +/- 2.05 l/min; p < 0,01) in acute heart failure. This comparison of hemodynamic parameters in addition to studies on myocardial oxygen consumption support the use of intravenous enoximone in acute heart failure, whereas the long-term application of enoximone in chronic heart failure is judged to be critical.
- Issue Date
- 1991
- Publisher
- Dr Dietrich Steinkopff Verlag
- Journal
- Zeitschrift für Kardiologie
- ISSN
- 0300-5860