Structure of the RBD-PRDI fragment of the antiterminator protein GlcT
2012 | journal article. A publication with affiliation to the University of Göttingen.
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Structure of the RBD-PRDI fragment of the antiterminator protein GlcT
Himmel, S.; Grosse, C.; Wolff, S.; Schwiegk, C. & Becker, S. (2012)
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, 68 pp. 751-756. DOI: https://doi.org/10.1107/S1744309112020635
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Details
- Authors
- Himmel, Sebastian; Grosse, Christian; Wolff, Sebastian; Schwiegk, C. ; Becker, Stefan
- Abstract
- GlcT is a transcriptional antiterminator protein that is involved in regulation of glucose metabolism in Bacillus subtilis. Antiterminator proteins bind specific RNA sequences, thus preventing the formation of overlapping terminator stem-loops. The structure of a fragment (residues 3-170) comprising the RNA-binding domain (RBD) and the first regulatory domain (PRDI) of GlcT was solved at 2.0 angstrom resolution with one molecule in the asymmetric unit. The two domains are connected by a helical linker. Their interface is mostly constituted by hydrophobic interactions.
- Issue Date
- 2012
- Journal
- ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS
- ISSN
- 1744-3091
- Sponsor
- Max Planck Society
