Successful treatment of a mycophenolate mofetil-refractory proliferative lupus nephritis with Belimumab in a 19-year-old woman
2013 | journal article. A publication with affiliation to the University of Göttingen.
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Successful treatment of a mycophenolate mofetil-refractory proliferative lupus nephritis with Belimumab in a 19-year-old woman
Fliesser, E. E.; Korsten, P. ; Koziolek, M. J. ; Niewold, T. B.; Patschan, D. ; Mueller, G. A. & Patschan, S. A. (2013)
Lupus, 22(14) pp. 1523-1525. DOI: https://doi.org/10.1177/0961203313504145
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Details
- Authors
- Fliesser, E. E.; Korsten, Peter ; Koziolek, Michael Johann ; Niewold, T. B.; Patschan, Daniel ; Mueller, Georg Anton; Patschan, Susann Andrea
- Abstract
- We report the case of a 19-year-old woman with progressive proliferative lupus nephritis (LN) class III after induction and maintenance therapy with mycophenolate mofetil (MMF). Despite a satisfying clinical improvement proteinuria progressed under this medication. We treated the patient with additional belimumab after discussing other options. Following treatment with belimumab, proteinuria rapidly improved to almost normal levels and clinical remission lasted. Belimumab might hold promise for this indication.
- Issue Date
- 2013
- Journal
- Lupus
- ISSN
- 1477-0962
- eISSN
- 0961-2033
- Language
- English
- Sponsor
- GlaxoSmithKline
