Tumor suppressors: Control of signaling by endocytosis

2006 | journal article???letter_note???. A publication with affiliation to the University of Göttingen.

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​Tumor suppressors: Control of signaling by endocytosis​
Giebel, B. & Wodarz, A.​ (2006) 
Current Biology, 16(3) pp. R91​-R92​.​ DOI: https://doi.org/10.1016/j.cub.2006.01.022 

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Authors
Giebel, B.; Wodarz, Andreas
Abstract
Genetic defects of the endosomal 'ESCRT' machinery in Drosophila have been found to cause loss of epithelial cell polarity, accompanied by overproliferation of mutant and adjacent wild-type cells. These results can be attributed to defective endocytosis of transmembrane proteins that control cell polarity and proliferation, including Crumbs and Notch.
Issue Date
2006
Status
published
Publisher
Cell Press
Journal
Current Biology 
ISSN
0960-9822

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