TiCl4-Catalyzed indirect anti-markovnikov hydration of alkynes: Application to the synthesis of benzo[b]furans
2007 | journal article. A publication with affiliation to the University of Göttingen.
Jump to: Cite & Linked | Documents & Media | Details | Version history
Cite this publication
TiCl4-Catalyzed indirect anti-markovnikov hydration of alkynes: Application to the synthesis of benzo[b]furans
Ackermann, L. & Kaspar, L. T. (2007)
The Journal of Organic Chemistry, 72(16) pp. 6149-6153. DOI: https://doi.org/10.1021/jo070887i
Documents & Media
Details
- Authors
- Ackermann, Lutz; Kaspar, Ludwig T.
- Abstract
- An efficient methodology for the indirect anti-Markovnikov hydration of unsymmetrically substituted terminal and internal alkynes is based on TiCl4-catalyzed hydroamination reactions. Its application to ortho-alkynylhaloarenes, followed by a copper-catalyzed O-arylation, provides flexible access to substituted benzo[b]furans.
- Issue Date
- 2007
- Status
- published
- Publisher
- Amer Chemical Soc
- Journal
- The Journal of Organic Chemistry
- ISSN
- 0022-3263
