Polymorphism of the gene of angiotensin converting enzyme: lack of association with mood disorder

2000 | journal article. A publication with affiliation to the University of Göttingen.

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​Polymorphism of the gene of angiotensin converting enzyme: lack of association with mood disorder​
Pauls, J.; Bandelow, B.; Ruther, E. & Kornhuber, J.​ (2000) 
Journal of Neural Transmission107(11) pp. 1361​-1366​.​ DOI: https://doi.org/10.1007/s007020070023 

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Authors
Pauls, J.; Bandelow, Borwin; Ruther, Eckart; Kornhuber, Johannes
Abstract
The insertion/deletion polymorphism of the gene of angiotensin-converting enzyme (ACE) was investigated in a case-control study including 169 patients with suffering from either bipolar disorder type I or unipolar recurrent major depression (DSM-IV) and 169 healthy controls. No significant association was found with bipolar disorder type I or unipolar recurrent depression and the polymorphism of the ACE gene. A previously reported genetic association (Arinami et al., 1996) was not confirmed by the present study.
Issue Date
2000
Status
published
Publisher
Springer
Journal
Journal of Neural Transmission 
ISSN
0300-9564

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