Isolation and sequence analysis of a novel rhesus macaque foamy virus isolate with a serotype-1-like env
2018 | journal article
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Isolation and sequence analysis of a novel rhesus macaque foamy virus isolate with a serotype-1-like env
Ensser, A.; Großkopf, A. K.; Mätz-Rensing, K. ; Roos, C. & Hahn, A. S. (2018)
Archives of Virology, 163(9) pp. 2507-2512. DOI: https://doi.org/10.1007/s00705-018-3892-9
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Details
- Authors
- Ensser, Armin; Großkopf, Anna K.; Mätz-Rensing, Kerstin ; Roos, Christian ; Hahn, Alexander S.
- Abstract
- SFVmmu-DPZ9524 represents the third completely sequenced rhesus macaque simian foamy virus (SFV) isolate, alongside SFVmmu_K3T with a similar SFV-1-type env, and R289HybAGM with a SFV-2-like env. Sequence analysis demonstrates that, in gag and pol, SFVmmu-DPZ9524 is more closely related to R289HybAGM than to SFVmmu_K3T, which, outside of env, is more similar to a Japanese macaque isolate than to the other two rhesus macaque isolates SFVmmu-DPZ9524 and R289HybAGM. Further, we identify bel as another recombinant locus in R289HybAGM, confirming that recombination contributes to sequence diversity in SFV.
- Issue Date
- 2018
- Journal
- Archives of Virology
- eISSN
- 1432-8798
- Language
- English