The role of frameless stereotactic biopsy in contemporary neuro-oncology: molecular specifications and diagnostic yield in biopsied glioma patients

2019 | journal article

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​The role of frameless stereotactic biopsy in contemporary neuro-oncology: molecular specifications and diagnostic yield in biopsied glioma patients​
Mader, M. M. Mader, Marius Marc-Daniel; Rotermund, R.; Martens, T.; Westphal, M.; Matschke, J. & Abboud, T. ​ (2019) 
Journal of Neuro-Oncology141(1) pp. 183​-194​.​ DOI: https://doi.org/10.1007/s11060-018-03024-8 

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Authors
Mader, Marius Marc-Daniel; Rotermund, Roman; Martens, Tobias; Westphal, Manfred; Matschke, Jakob; Abboud, Tammam 
Abstract
With the 2016 World Health Organization Classification of Tumors of the Central Nervous System (2016 CNS WHO), diagnosis of glioma is based on molecular parameters in addition to histology potentially leading to additional demands on quality of tissue samples. This may challenge the role of minimally invasive biopsy procedures. This study aims to evaluate the diagnostic yield of glioma samples from frameless stereotactic biopsies with focus on molecular information and explore the neuromolecular profile of a glioma biopsy cohort.
Issue Date
2019
Journal
Journal of Neuro-Oncology 
eISSN
1573-7373
Language
English

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