Real-time flow MRI of the aorta at a resolution of 40 msec.
2014-07-01 | journal article. A publication with affiliation to the University of Göttingen.
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Real-time flow MRI of the aorta at a resolution of 40 msec.
Joseph, A.; Kowallick, J. T.; Merboldt, K.-D.; Voit, D.; Schaetz, S.; Zhang, S. & Sohns, J. M. et al. (2014)
Journal of magnetic resonance imaging : JMRI, 40(1) pp. 206-213. DOI: https://doi.org/10.1002/jmri.24328
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- Authors
- Joseph, Arun; Kowallick, Johannes T.; Merboldt, Klaus-Dietmar; Voit, Dirk; Schaetz, Sebastian; Zhang, Shuo; Sohns, Jan M.; Lotz, Joachim ; Frahm, Jens
- Abstract
- PURPOSE: To evaluate a novel real-time phase-contrast magnetic resonance imaging (MRI) technique for the assessment of through-plane flow in the ascending aorta. MATERIALS AND METHODS: Real-time MRI was based on a radial fast low-angle shot (FLASH) sequence with about 30-fold undersampling and image reconstruction by regularized nonlinear inversion. Phase-contrast maps were obtained from two (interleaved or sequential) acquisitions with and without a bipolar velocity-encoding gradient. Blood flow in the ascending aorta was studied in 10 healthy volunteers at 3 T by both real-time MRI (15 sec during free breathing) and electrocardiogram (ECG)-synchronized cine MRI (with and without breath holding). Flow velocities and stroke volumes were evaluated using standard postprocessing software. RESULTS: The total acquisition time for a pair of phase-contrast images was 40.0 msec (TR/TE = 2.86/1.93 msec, 10° flip angle, 7 spokes per image) for a nominal in-plane resolution of 1.3 mm and a section thickness of 6 mm. Quantitative evaluations of spatially averaged flow velocities and stroke volumes were comparable for real-time and cine methods when real-time MRI data were averaged across heartbeats. For individual heartbeats real-time phase-contrast MRI resulted in higher peak velocities for values above 120 cm s(-1). CONCLUSION: Real-time phase-contrast MRI of blood flow in the human aorta yields functional parameters for individual heartbeats. When averaged across heartbeats real-time flow velocities and stroke volumes are comparable to values obtained by conventional cine MRI.
- Issue Date
- 1-July-2014
- Journal
- Journal of magnetic resonance imaging : JMRI
- ISSN
- 1522-2586
- Language
- English