Multiple, Multiloculated, and Recurrent Keratocysts of the Mandible and Maxilla in Association with Gorlin-Goltz (Nevoid Basal-Cell Carcinoma) Syndrome: A Pediatric Case Report and Follow-up over 5 Years
2018 | journal article. A publication with affiliation to the University of Göttingen.
Jump to: Cite & Linked | Documents & Media | Details | Version history
Cite this publication
Multiple, Multiloculated, and Recurrent Keratocysts of the Mandible and Maxilla in Association with Gorlin-Goltz (Nevoid Basal-Cell Carcinoma) Syndrome: A Pediatric Case Report and Follow-up over 5 Years
Santander, P.; Schwaibold, E. M. C.; Bremmer, F.; Batschkus, S. & Kauffmann, P. (2018)
Case Reports in Dentistry, 2018 pp. 1-8. DOI: https://doi.org/10.1155/2018/7594840
Documents & Media
Details
- Authors
- Santander, P.; Schwaibold, E. M. C.; Bremmer, F.; Batschkus, S.; Kauffmann, P.
- Abstract
- We report a case of multiple keratocysts first diagnosed in an 8-year-old boy. Case report. The incidental radiographic finding of a cystic lesion in an 8-year-old boy led to the surgical enucleation and further diagnosis of a keratocyst associated with a tooth crown. In the course of dental maturation from deciduous to permanent teeth, the boy presented new lesions, always associated with the crowns of teeth. Gorlin-Goltz (nevoid basal-cell carcinoma) syndrome was suspected, and the genetic analysis detected a previously undescribed germline variant in the PTCH1 gene. Treatment. This included a surgical removal of the cystic lesions, as well as the affected teeth. Follow-up. Due to the high recurrence rate of the keratocysts, frequent radiological checks were performed over a 5-year period.
- Issue Date
- 2018
- Journal
- Case Reports in Dentistry
- Organization
- Poliklinik für Kieferorthopädie ; Institut für Humangenetik ; Institut für Pathologie ; Klinik für Mund-, Kiefer- und Gesichtschirurgie
- ISSN
- 2090-6455
- Language
- English