Proteomic Analysis of Azole Resistance in Candida albicans Clinical Isolates

2004 | journal article. A publication with affiliation to the University of Göttingen.

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​Proteomic Analysis of Azole Resistance in Candida albicans Clinical Isolates​
Hooshdaran, M. Z.; Barker, K. S.; Hilliard, G. M.; Kusch, H. ; Morschhäuser, J. & Rogers, P. D.​ (2004) 
Antimicrobial Agents and Chemotherapy, pp. 2733​-2735​.​ DOI: https://doi.org/10.1128/AAC.48.7.2733-2735.2004 

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Authors
Hooshdaran, Massoumeh Z.; Barker, Katherine S.; Hilliard, George M.; Kusch, Harald ; Morschhäuser, Joachim; Rogers, P. David
Abstract
Changes in protein expression within a matched set of Candida albicans isolates representing the acquisition of azole resistance were examined by two-dimensional polyacrylamide gel electrophoresis and peptide mass fingerprinting. Proteins differentially expressed in association with azole resistance included Grp2p, Ifd1p, Ifd4p, Ifd5p, and Erg10p, a protein involved in the ergosterol biosynthesis pathway.
Issue Date
2004
Journal
Antimicrobial Agents and Chemotherapy 
ISSN
1098-6596
Language
English

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