Phase-contrast tomography of sciatic nerves: image quality and experimental parameters
2017-06-14 | journal article; research paper. A publication with affiliation to the University of Göttingen.
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Phase-contrast tomography of sciatic nerves: image quality and experimental parameters
Töpperwien, M. ; Krenkel, M.; Ruhwedel, T.; Möbius, W. ; Pacureanu, A.; Cloetens, P. & Salditt, T. (2017)
Journal of Physics. Conference Series, 849 art. 012001. DOI: https://doi.org/10.1088/1742-6596/849/1/012001
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Details
- Authors
- Töpperwien, Mareike ; Krenkel, Martin; Ruhwedel, Torben; Möbius, Wiebke ; Pacureanu, A.; Cloetens, Peter; Salditt, Tim
- Abstract
- We present propagation-based phase-contrast tomography of mouse sciatic nerves stained with osmium, leading to an enhanced contrast in the myelin sheath around the axons, in order to visualize the threedimensional (3D) structure of the nerve. We compare different experimental parameters and show that contrast and resolution are high enough to identify single axons in the nerve, including characteristic functional structures such as Schmidt-Lanterman incisures.
- Issue Date
- 14-June-2017
- Journal
- Journal of Physics. Conference Series
- Organization
- Institut für Röntgenphysik
- Working Group
- RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics)
- ISSN
- 1742-6588; 1742-6596
- Language
- English
- Subject(s)
- x-ray imaging; biomedical tomography
