Nanoscale holographic tomography of heart tissue with x-ray waveguide optics

2017-09-25 | conference paper. A publication with affiliation to the University of Göttingen.

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​Nanoscale holographic tomography of heart tissue with x-ray waveguide optics​
Nicolas, J. D.; Markus, M. A. ; Alves, F. ; Frohn, J. ; Reichardt, M.; Töpperwien, M.   & Salditt, T. ​ (2017)
In:Wang, Geng; Müller-Myhsok, Bertram​ (Eds.), p. 4. , San Diego. DOI: https://doi.org/10.1117/12.2276648 

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Authors
Nicolas, J. D.; Markus, Marietta Andrea ; Alves, Frauke ; Frohn, Jasper ; Reichardt, Marius; Töpperwien, Mareike ; Salditt, Tim 
Editors
Wang, Geng; Müller-Myhsok, Bertram
Abstract
In this work we present x-ray phase-contrast tomography of heart tissue from mouse, combining computed tomography (CT) scans with laboratory and synchrotron radiation. The work serves as a proof-of-concept that the cyto-architecture and in particular the myofibril orientation can be assessed in three dimensions (3D) by phase-contrast CT. We demonstrate the synergistic use of laboratory μ -CT and of the high resolution synchrotron setup based on waveguide optics. Details on preparation, instrumentation and analysis are given, as a state of the art reference for heart tissue tomography, and as a starting point for further progress.
Issue Date
25-September-2017
Organization
Institut für Röntgenphysik 
Working Group
RG Salditt (Structure of Biomolecular Assemblies and X-Ray Physics) 
ISBN
9781510612396
9781510612402
Conference Place
San Diego
Event start
2017-09-25
Event end
2017-09-25
Language
English
Subject(s)
x-ray optics; x-ray imaging; biomedical tomography

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