Outcome in patients with small cell lung cancer re-irradiated for brain metastases after prior prophylactic cranial irradiation

2016 | journal article

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​Outcome in patients with small cell lung cancer re-irradiated for brain metastases after prior prophylactic cranial irradiation​
Bernhardt, D.; Bozorgmehr, F.; Adeberg, S.; Opfermann, N.; von Eiff, D.; Rieber, J. & Kappes, J. et al.​ (2016) 
Lung Cancer101 pp. 76​-81​.​ DOI: https://doi.org/10.1016/j.lungcan.2016.09.010 

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Authors
Bernhardt, Denise; Bozorgmehr, Farastuk; Adeberg, Sebastian; Opfermann, Nils; von Eiff, Damian; Rieber, Juliane; Kappes, Jutta; Foerster, Robert; König, Laila; Thomas, Michael; Debus, Jürgen; Steins, Martin; Rieken, Stefan 
Abstract
Patients with brain metastases from small-cell lung cancer (SCLC) who underwent prior prophylactic cranial irradiation (PCI) are often treated with a second course of whole brain radiation therapy (Re-WBRT) or stereotactic radiosurgery (SRS) for purposes of palliation in symptomatic patients, hope for increased life expectancy or even as an alternative to untolerated steroids. Up to date there is only limited data available regarding the effect of this treatment. This study examines outcomes in patients in a single institution who underwent cerebral re-irradiation after prior PCI.
Issue Date
2016
Journal
Lung Cancer 
ISSN
0169-5002
eISSN
1872-8332
Language
English

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