Targeting ανβ3 and ανβ5 inhibits photon-induced hypermigration of malignant glioma cells

2011-10-06 | journal article

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​Targeting ανβ3 and ανβ5 inhibits photon-induced hypermigration of malignant glioma cells​
Rieken, S. ; Habermehl, D.; Mohr, A.; Wuerth, L.; Lindel, K.; Weber, K. & Debus, J. et al.​ (2011) 
Radiation oncology, 6(1) pp. 132​.​ DOI: https://doi.org/10.1186/1748-717X-6-132 

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Authors
Rieken, Stefan ; Habermehl, Daniel; Mohr, Angela; Wuerth, Lena; Lindel, Katja; Weber, Klaus; Debus, Jürgen; Combs, Stephanie E
Abstract
Sublethal photon irradiation was recently suspected to increase tumor cell motility and promote locoregional recurrence of disease. This study was set up to describe mechanisms underlying increased glioma cell migration through photon irradiation and to analyse the modifiability of photon-altered glioma cell motility by integrin inhibition.
Issue Date
6-October-2011
Journal
Radiation oncology 
ISSN
1748-717X
Language
English

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