Whole brain radiation therapy alone versus radiosurgery for patients with 1-10 brain metastases from small cell lung cancer (ENCEPHALON Trial): study protocol for a randomized controlled trial

2018-07-16 | journal article

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​Whole brain radiation therapy alone versus radiosurgery for patients with 1-10 brain metastases from small cell lung cancer (ENCEPHALON Trial): study protocol for a randomized controlled trial​
Bernhardt, D.; Hommertgen, A.; Schmitt, D.; El Shafie, R. ; Paul, A.; König, L. & Mair-Walther, J. et al.​ (2018) 
Trials19(1) pp. 388​.​ DOI: https://doi.org/10.1186/s13063-018-2745-x 

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Authors
Bernhardt, Denise; Hommertgen, Adriane; Schmitt, Daniela; El Shafie, Rami ; Paul, Angela; König, Laila; Mair-Walther, Johanna; Krisam, Johannes; Klose, Christina; Welzel, Thomas; Hörner-Rieber, Juliane; Kappes, Jutta; Thomas, Michael; Heußel, Claus Peter; Steins, Martin; Kieser, Meinhard; Debus, Jürgen; Rieken, Stefan 
Abstract
Conventional whole brain radiotherapy (WBRT) has been established as the treatment standard in patients with cerebral metastases from small-cell lung cancer (SCLC), however, it has only modest efficacy and limited prospective data is available for WBRT as well as local treatments such as stereotactic radiosurgery (SRS).
Issue Date
16-July-2018
Journal
Trials 
ISSN
1745-6215
Language
English

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