Distilling complexity to advance cardiac tissue engineering
2016 | journal article; research paper. A publication with affiliation to the University of Göttingen.
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Distilling complexity to advance cardiac tissue engineering
Ogle, B. M.; Bursac, N.; Domian, I.; Huang, N. F.; Menasche, P.; Murry, C. E. & Pruitt, B. et al. (2016)
Science Translational Medicine, 8(342) art. 342ps13. DOI: https://doi.org/10.1126/scitranslmed.aad2304
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Details
- Authors
- Ogle, Brenda M.; Bursac, Nenad; Domian, Ibrahim; Huang, Ngan F.; Menasche, Philippe; Murry, Charles E.; Pruitt, Beth; Radisic, Milica; Wu, Joseph C.; Wu, Sean M.; Zhang, Jianyi; Zimmermann, Wolfram-Hubertus ; Vunjak-Novakovic, Gordana
- Abstract
- The promise of cardiac tissue engineering is in the ability to recapitulate in vitro the functional aspects of a healthy heart and disease pathology as well as to design replacement muscle for clinical therapy. Parts of this promise have been realized; others have not. In a meeting of scientists in this field, five central challenges or "big questions" were articulated that, if addressed, could substantially advance the current state of the art in modeling heart disease and realizing heart repair.
- Issue Date
- 2016
- Publisher
- Amer Assoc Advancement Science
- Journal
- Science Translational Medicine
- ISSN
- 1946-6234
- eISSN
- 1946-6242