Cement augmentation versus extended dorsal instrumentation in the treatment of osteoporotic vertebral fractures

Abstract

Aims Loosening of pedicle screws is a major complication of posterior spinal stabilisation, especially in the osteoporotic spine. Our aim was to evaluate the effect of cement augmentation compared with extended dorsal instrumentation on the stability of posterior spinal fixation. Materials and Methods A total of 12 osteoporotic human cadaveric spines ( T11-L3) were randomised by bone mineral density into two groups and instrumented with pedicle screws: group I ( SHORT) separated T12 or L2 and group II ( EXTENDED) specimen consisting of T11/12 to L2/3. Screws were augmented with cement unilaterally in each vertebra. Fatigue testing was performed using a cranial-caudal sinusoidal, cyclic ( 1.0 Hz) load with stepwise increasing peak force. Results Augmentation showed no significant increase in the mean cycles to failure and fatigue force ( SHORT p = 0.067; EXTENDED p = 0.239). Extending the instrumentation resulted in a significantly increased number of cycles to failure and a significantly higher fatigue force compared with the SHORT instrumentation ( EXTENDED non-augmented +76%, p < 0.001; EXTENDED augmented +87%, p < 0.001). Conclusion The stabilising effect of cement augmentation of pedicle screws might not be as beneficial as expected from biomechanical pull-out tests. Lengthening the dorsal instrumentation results in a much higher increase of stability during fatigue testing in the osteoporotic spine compared with cement augmentation.