Recyclable Ruthenium Catalyst for Distal meta ‐C−H Activation
2020 | journal article. A publication with affiliation to the University of Göttingen.
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- Authors
- Choi, Isaac; Müller, Valentin; Wang, Yanhui; Xue, Kai; Kuniyil, Rositha; Andreas, Loren B.; Karius, Volker ; Alauzun, Johan G.; Ackermann, Lutz
- Abstract
- Abstract We disclose the unprecedented hybrid‐ruthenium catalysis for distal meta‐C−H activation. The hybrid‐ruthenium catalyst was recyclable, as was proven by various heterogeneity tests, and fully characterized with various microscopic and spectroscopic techniques, highlighting the physical and chemical stability. Thereby, the hybrid‐ruthenium catalysis proved broadly applicable for meta‐C−H alkylations of among others purine‐based nucleosides and natural product conjugates. Additionally, its versatility was further reflected by meta‐C−H activations through visible‐light irradiation, as well as para‐selective C−H activations.
Don't say goodbye! Recyclable ruthenium catalyst enabled diverse distal C−H functionalization. State‐of‐the‐art spectroscopic and spectrometric characterizations highlighted physical and chemical stability of reusable hybrid‐ruthenium catalyst. Robustness and versatility of hybrid‐ruthenium catalysis was further reflected by meta‐ and para‐selectivity as well as visible‐light‐induced reactivity. image - Issue Date
- 2020
- Journal
- Chemistry – A European Journal
- ISSN
- 0947-6539
- eISSN
- 1521-3765
- Language
- English
- Sponsor
- Horizon 2020 Framework Programme http://dx.doi.org/10.13039/100010661
Kwanjeong Educational Foundation http://dx.doi.org/10.13039/501100004093
DFG http://dx.doi.org/10.13039/501100001659
Max Planck Institute for Biophysical Chemistry