Neurodevelopment in the third year of life in children with antenatal ZIKV-exposure

2021 | journal article. A publication with affiliation to the University of Göttingen.

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​Neurodevelopment in the third year of life in children with antenatal ZIKV-exposure​
Aizawa, C. Y. P.; Caron, D. M. R.; Souza, C. B.; Kozima, P. F. A.; Damasceno, L.; Einspieler, C. & Marschik, P. B. et al.​ (2021) 
Revista de Saúde Pública55 pp. 15​.​ DOI: https://doi.org/10.11606/s1518-8787.2021055002798 

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Authors
Aizawa, Carolina Yuri Panvequio; Caron, Deyse Mayara Rodrigues; Souza, Carolina Barbosa; Kozima, Paula Fernanda Augusto; Damasceno, Luana; Einspieler, Christa; Marschik, Peter B.; Brasil, Patrícia; Schmitt, Ana Carolina Basso; Hasue, Renata Hydee
Abstract
We report cognitive, language and motor neurodevelopment, assessed by the Bayley-III test, in 31 non-microcephalic children at age 3 with PCR-confirmed maternal Zika virus exposure (Rio de Janeiro, 2015–2016). Most children had average neurodevelopmental scores, however, 8 children (26%) presented delay in some domain. Language was the most affected: 7 children (22.6%) had a delay in this domain (2 presenting severe delay). Moderate delay was detected in the cognitive (3.2%) and motor (10%) domains. Maternal illness in the third trimester of pregnancy and later gestational age at birth were associated with higher Bayley-III scores. Zika-exposed children require long-term follow-up until school age.
Issue Date
2021
Journal
Revista de Saúde Pública 
ISSN
0034-8910
eISSN
1518-8787

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