Right inferior frontal gyrus implements motor inhibitory control via beta-band oscillations in humans
2021 | journal article; research paper. A publication with affiliation to the University of Göttingen.
Jump to: Cite & Linked | Documents & Media | Details | Version history
Cite this publication
Right inferior frontal gyrus implements motor inhibitory control via beta-band oscillations in humans
Schaum, M.; Pinzuti, E.; Sebastian, A.; Lieb, K.; Fries, P.; Mobascher, A. & Jung, P. et al. (2021)
eLife, 10. DOI: https://doi.org/10.7554/eLife.61679
Documents & Media
Details
- Authors
- Schaum, Michael; Pinzuti, Edoardo; Sebastian, Alexandra; Lieb, Klaus; Fries, Pascal; Mobascher, Arian; Jung, Patrick; Wibral, Michael ; Tüscher, Oliver
- Abstract
- Motor inhibitory control implemented as response inhibition is an essential cognitive function required to dynamically adapt to rapidly changing environments. Despite over a decade of research on the neural mechanisms of response inhibition, it remains unclear, how exactly response inhibition is initiated and implemented. Using a multimodal MEG/fMRI approach in 59 subjects, our results reliably reveal that response inhibition is initiated by the right inferior frontal gyrus (rIFG) as a form of attention-independent top-down control that involves the modulation of beta-band activity. Furthermore, stopping performance was predicted by beta-band power, and beta-band connectivity was directed from rIFG to pre-supplementary motor area (pre-SMA), indicating rIFG’s dominance over pre-SMA. Thus, these results strongly support the hypothesis that rIFG initiates stopping, implemented by beta-band oscillations with potential to open up new ways of spatially localized oscillation-based interventions.
- Issue Date
- 2021
- Journal
- eLife
- eISSN
- 2050-084X
- Language
- English