CSF characteristics in early-onset multiple sclerosis
2004 | journal article. A publication with affiliation to the University of Göttingen.
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Details
- Authors
- Pohl, D.; Rostasy, K.; Reiber, H.; Hanefeld, F.
- Abstract
- The authors studied CSF characteristics in 136 patients with multiple sclerosis ( MS) with a disease onset before age 16. In the initial diagnostic lumbar puncture, CSF-pleocytosis was observed in 66%, blood-CSF barrier dysfunction in 13%, and oligoclonal IgG in 92% of the early-onset MS (EOMS) patients. CSF oligoclonal IgG supports the early diagnosis of MS in childhood with a sensitivity similar to adult-onset MS.
- Issue Date
- 2004
- Status
- published
- Publisher
- Lippincott Williams & Wilkins
- Journal
- Neurology
- ISSN
- 0028-3878
- eISSN
- 1526-632X
- Language
- English