CSF characteristics in early-onset multiple sclerosis

2004 | journal article. A publication with affiliation to the University of Göttingen.

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​CSF characteristics in early-onset multiple sclerosis​
Pohl, D.; Rostasy, K.; Reiber, H. & Hanefeld, F.​ (2004) 
Neurology63(10) pp. 1966​-1967​.​ DOI: https://doi.org/10.1212/01.WNL.0000144352.67102.BC 

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Authors
Pohl, D.; Rostasy, K.; Reiber, H.; Hanefeld, F.
Abstract
The authors studied CSF characteristics in 136 patients with multiple sclerosis ( MS) with a disease onset before age 16. In the initial diagnostic lumbar puncture, CSF-pleocytosis was observed in 66%, blood-CSF barrier dysfunction in 13%, and oligoclonal IgG in 92% of the early-onset MS (EOMS) patients. CSF oligoclonal IgG supports the early diagnosis of MS in childhood with a sensitivity similar to adult-onset MS.
Issue Date
2004
Status
published
Publisher
Lippincott Williams & Wilkins
Journal
Neurology 
ISSN
0028-3878
eISSN
1526-632X
Language
English

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