Silica precipitation with synthetic silaffin peptides
2011 | Zeitschriftenartikel; Forschungsarbeit. Eine Publikation mit Affiliation zur Georg-August-Universität Göttingen.
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Details
- Autor(en)
- Wieneke, Ralph; Bernecker, Anja; Riedel, Radostan; Sumper, Manfred; Steinem, Claudia ; Geyer, Armin
- Zusammenfassung
- Silaffins are highly charged proteins which are one of the major contributing compounds that are thought to be responsible for the formation of the hierarchically structured silica-based cell walls of diatoms. Here we describe the synthesis of an oligo-propyleneamine substituted lysine derivative and its incorporation into the KXXK peptide motif occurring repeatedly in silaffins. Ne-alkylation of lysine was achieved by a Mitsunobu reaction to obtain a protected lysine derivative which is convenient for solid phase peptide synthesis. Quantitative silica precipitation experiments together with structural information about the precipitated silica structures gained by scanning electron microscopy revealed a dependence of the amount and form of the silica precipitates on the peptide structure.
- Erscheinungsdatum
- 2011
- Zeitschrift
- Organic & Biomolecular Chemistry
- Organisation
- Fakultät für Chemie
- ISSN
- 1477-0520
- Sprache
- Englisch
- Anmerkung
- This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.