JCI Insight

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American Society for Clinical Investigation
 
 
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  • 2022 Journal Article | 
    ​ ​Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis​
    O’Sullivan, E. D.; Mylonas, K. J.; Bell, R.; Carvalho, C.; Baird, D. P.; Cairns, C. & Gallagher, K. M. et al.​ (2022) 
    JCI Insight7(22) art. e154124​.​ DOI: https://doi.org/10.1172/jci.insight.154124 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Temporary antimetabolite treatment hold boosts SARS-CoV-2 vaccination-specific humoral and cellular immunity in kidney transplant recipients​
    Schrezenmeier, E.; Rincon-Arevalo, H.; Jens, A.; Stefanski, A.-L.; Hammett, C.; Osmanodja, B. & Koch, N. et al.​ (2022) 
    JCI Insight,.​ DOI: https://doi.org/10.1172/jci.insight.157836 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Epigenetic drug screening defines a PRMT5 inhibitor–sensitive pancreatic cancer subtype​
    Orben, F.; Lankes, K.; Schneeweis, C.; Hassan, Z.; Jakubowsky, H.; Krauß, L. & Boniolo, F. et al.​ (2022) 
    JCI Insight7(10) art. e151353​.​ DOI: https://doi.org/10.1172/jci.insight.151353 
    Details  DOI 
  • 2022 Journal Article | Research Paper | 
    ​ ​Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer​
    Krebs, N.; Klein, L.; Wegwitz, F. ; Espinet, E.; Maurer, H. C.; Tu, M. & Penz, F. et al.​ (2022) 
    JCI Insight7(16) art. e154475​.​ DOI: https://doi.org/10.1172/jci.insight.154475 
    Details  DOI 
  • 2022 Journal Article | Research Paper | 
    ​ ​Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation​
    Linnerbauer, M.; Lößlein, L.; Vandrey, O.; Tsaktanis, T.; Beer, A.; Naumann, U. J. & Panier, F. et al.​ (2022) 
    JCI Insight7(7).​ DOI: https://doi.org/10.1172/jci.insight.154824 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | 
    ​ ​Complex consequences of Cantu syndrome SUR2 variant R1154Q in genetically modified mice​
    Zhang, H.; Hanson, A.; de Almeida, T. S.; Emfinger, C.; McClenaghan, C.; Harter, T. & Yan, Z. et al.​ (2021) 
    JCI Insight6(5).​ DOI: https://doi.org/10.1172/jci.insight.145934 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​Longitudinally persistent cerebrospinal fluid B-cells can resist treatment in multiple sclerosis​
    Greenfield, A. L.; Dandekar, R.; Ramesh, A.; Eggers, E. L.; Wu, H.; Laurent, S. & Harkin, W. et al.​ (2019) 
    JCI Insight,.​ DOI: https://doi.org/10.1172/jci.insight.126599 
    Details  DOI 
  • 2019 Journal Article | Research Paper | 
    ​ ​Junctophilin-2 expression rescues atrial dysfunction through polyadic junctional membrane complex biogenesis​
    Brandenburg, S. ; Pawlowitz, J.; Eikenbusch, B.; Peper, J.; Kohl, T. ; Mitronova, G. Y.   & Sossalla, S.  et al.​ (2019) 
    JCI insight4(12).​ DOI: https://doi.org/10.1172/jci.insight.127116 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Research Paper | 
    ​ ​Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish​
    Burczyk, M. S.; Burkhalter, M. D.; Tena, T. C.; Grisanti, L. A.; Kauk, M.; Matysik, S. & Donow, C. et al.​ (2019) 
    JCI Insight4(20).​ DOI: https://doi.org/10.1172/jci.insight.121971 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | 
    ​ ​Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities​
    Christov, M.; Clark, A. R.; Corbin, B.; Hakroush, S.; Rhee, E. P.; Saito, H. & Brooks, D. et al.​ (2018) 
    JCI Insight3(4).​ DOI: https://doi.org/10.1172/jci.insight.95091 
    Details  DOI 
  • 2018 Journal Article | Research Paper | 
    ​ ​Deep phenotyping of human induced pluripotent stem cell–derived atrial and ventricular cardiomyocytes​
    Cyganek, L. ; Tiburcy, M. ; Sekeres, K.; Gerstenberg, K.; Bohnenberger, H. ; Lenz, C.   & Henze, S.  et al.​ (2018) 
    JCI Insight3(12) art. e99941​.​ DOI: https://doi.org/10.1172/jci.insight.99941 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | 
    ​ ​Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia​
    Karamita, M.; Barnum, C.; Möbius, W. ; Tansey, M. G.; Szymkowski, D. E.; Lassmann, H. & Probert, L.​ (2017) 
    JCI Insight2(8).​ DOI: https://doi.org/10.1172/jci.insight.87455 
    Details  DOI 
  • 2017 Journal Article | Research Paper | 
    ​ ​Functional correction of dystrophin actin binding domain mutations by genome editing​
    Kyrychenko, V.; Kyrychenko, S.; Tiburcy, M. ; Shelton, J. M.; Long, C.; Schneider, J. W. & Zimmermann, W.-H.  et al.​ (2017) 
    JCI Insight2(18) art. e95918​.​ DOI: https://doi.org/10.1172/jci.insight.95918 
    Details  DOI  PMID  PMC 

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