Prof. Dr. Mathias Bähr

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  • 2022 | Journal Article | Research Paper | 
    ​ ​Michel U, Shomroni O, Müller B, Lange P, Salinas G, Bähr M, et al. ​Small and long RNA transcriptome of whole human cerebrospinal fluid and serum as compared to their extracellular vesicle fractions reveal profound differences in expression patterns and impacts on biological processes​. ​​Journal of Translational Medicine. ​2022;​20​(1). ​doi:10.1186/s12967-022-03612-3. 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Maass F, Hermann P, Varges D, Nuhn S, van Riesen C, Jamous A, et al. ​Prospective CERAD Neuropsychological Assessment in Patients With Multiple System Atrophy​. ​​Frontiers in Neurology. ​2022;​13​. ​doi:10.3389/fneur.2022.881369. 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Leite K, Garg P, Spitzner FP, Guerin Darvas S, Bähr M, Priesemann V, et al. ​α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals​. ​​Frontiers in Molecular Neuroscience. ​2022;​15​. ​doi:10.3389/fnmol.2022.868790. 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Haupt M, Gerner ST, Bähr M, Doeppner TR. ​Quest for Quality in Translational Stroke Research—A New Dawn for Neuroprotection?​. ​​International Journal of Molecular Sciences. ​2022;​23​(10):​​5381​. ​doi:10.3390/ijms23105381. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Hermann DM, Xin W, Bähr M, Giebel B, Doeppner TR. ​Emerging roles of extracellular vesicle-associated non-coding RNAs in hypoxia: Insights from cancer, myocardial infarction and ischemic stroke​. ​​Theranostics. ​2022;​12​(13):​​5776​-5802​. ​doi:10.7150/thno.73931. 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Bartl M, Xylaki M, Bähr M, Weber S, Trenkwalder C, Mollenhauer B. ​Evidence for immune system alterations in peripheral biological fluids in Parkinson's disease​. ​​Neurobiology of Disease. ​2022;​170​:​​105744​. ​doi:10.1016/j.nbd.2022.105744. 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper
    ​ ​Garg P, Maass F, Sundaram SM, Mollenhauer B, Mahajani S, van Riesen C, et al. ​The relevance of synuclein autoantibodies as a biomarker for Parkinson's disease​. ​​Molecular and Cellular Neuroscience. ​2022;​121​. ​doi:10.1016/j.mcn.2022.103746. 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | 
    ​ ​Hofmann M, Biller L, Michel U, Bähr M, Koch, Jan-Christoph. ​Cytoskeletal assembly in axonal outgrowth and regeneration analyzed on the nanoscale​. ​​Scientific Reports. ​2022;​12​(1). ​doi:10.1038/s41598-022-18562-5. 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Psol M, Darvas SG, Leite K, Mahajani S, Bähr M, Kügler S. ​Dementia with Lewy bodies—associated ß-synuclein mutations V70M and P123H cause mutation-specific neuropathological lesions​. ​​Human Molecular Genetics. ​2021;​30​(3-4):​​247​-264​. ​doi:10.1093/hmg/ddab036. 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Mahajani S, Bähr M, Kügler S. ​Patterning inconsistencies restrict the true potential of dopaminergic neurons derived from human induced pluripotent stem cells​. ​​Neural Regeneration Research. ​2021;​16​(4):​​692​. ​doi:10.4103/1673-5374.295316. 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Cheng S, van Gaalen MM, Bähr M, Garea-Rodriguez E, Kügler S. ​Optimized pharmacological control over the AAV-Gene-Switch vector for regulable gene therapy​. ​​Molecular Therapy - Methods & Clinical Development. ​2021;​23​:​​1​-10​. ​doi:10.1016/j.omtm.2021.07.007. 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Caldi Gomes L, Roser A, Jain G, Pena Centeno T, Maass F, Schilde L, et al. ​MicroRNAs from extracellular vesicles as a signature for Parkinson's disease​. ​​Clinical and Translational Medicine. ​2021;​11​(4). ​doi:10.1002/ctm2.357. 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Xin, Wen-Qiang, Wei W, Pan, Yong-Li, Cui, Bao-Long, Yang, Xin-Yu, Bähr M, et al. ​Modulating poststroke inflammatory mechanisms: Novel aspects of mesenchymal stem cells, extracellular vesicles and microglia​. ​​World Journal of Stem Cells. ​2021;​13​(8):​​1030​-1048​. ​doi:10.4252/wjsc.v13.i8.1030. 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Markworth R, Bähr M, Burk K. ​Held Up in Traffic—Defects in the Trafficking Machinery in Charcot-Marie-Tooth Disease​. ​​Frontiers in Molecular Neuroscience. ​2021;​14​. ​doi:10.3389/fnmol.2021.695294. 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Maass F, Michalke B, Willkommen D, Canaslan S, Schmitz M, Bähr M, et al. ​Cerebrospinal Fluid Iron‐Ferritin Ratio as a Potential Progression Marker for Parkinson's Disease​. ​​Movement Disorders. ​2021;. ​doi:10.1002/mds.28790. 
    ​Details  DOI 
  • 2021 | Conference Abstract
    ​ ​Schnieder M, Baehr M, Kirsch M, Behme D, Riedel C, Psychogios M, et al. ​Der Einfluss von Frailty auf das neurologische Outcome und die Mortalität nach mechanischer Thrombektomie bei Schlaganfällen​. ​ 33. Jahreskongress der Deutschen Gesellschaft für Geriatrie; ​2021-09-02​ - 2021-09-04​; ​​virtuell. ​Zeitschrift für Gerontologie und Geriatrie. ​2021;​54​(Suppl. 1):S58​. ​
    ​Details  WoS 
  • 2021 | Journal Article
    ​ ​Haupt M, Bähr M, Doeppner TR. ​Lithium beyond psychiatric indications: the reincarnation of a new old drug​. ​​Neural Regeneration Research. ​2021;​16​(12):​​2383​. ​doi:10.4103/1673-5374.313015. 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Kottlarz I, Berg S, Toscano-Tejeida D, Steinmann I, Bähr M, Luther S, et al. ​Extracting Robust Biomarkers From Multichannel EEG Time Series Using Nonlinear Dimensionality Reduction Applied to Ordinal Pattern Statistics and Spectral Quantities​. ​​Frontiers in Physiology. ​2021;​11​. ​doi:10.3389/fphys.2020.614565. 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Bähr M. ​Über die systemmedizinische Analyse zur personalisierten Neurologie​. ​​Der Nervenarzt. ​2021;​92​(10):​​975​-976​. ​doi:10.1007/s00115-021-01177-y. 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Zheng X, Hermann DM, Bähr M, Doeppner TR. ​The role of small extracellular vesicles in cerebral and myocardial ischemia-Molecular signals, treatment targets, and future clinical translation​. ​​Stem Cells. ​2021;​39​(4):​​403​-413​. ​doi:10.1002/stem.3329. 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Zhang L, Wei W, Ai X, Kilic E, Hermann DM, Venkataramani V, et al. ​Extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-β/Smad2/3 pathway​. ​​Cell Death & Disease. ​2021;​12​(11). ​doi:10.1038/s41419-021-04363-7. 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Schnieder M, Bähr M, Kirsch M, Maier I, Behme D, Riedel CH, et al. ​Analysis of Frailty in Geriatric Patients as a Prognostic Factor in Endovascular Treated Patients with Large Vessel Occlusion Strokes​. ​​Journal of Clinical Medicine. ​2021;​10​(10):​​2171​. ​doi:10.3390/jcm10102171. 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Liman J, Wolff von Gudenberg A, Baehr M, Paulus W, Neef NE, Sommer M. ​Enlarged Area of Mesencephalic Iron Deposits in Adults Who Stutter​. ​​Frontiers in Human Neuroscience. ​2021;​15​. ​doi:10.3389/fnhum.2021.639269. 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Janssen L, Ai X, Zheng X, Wei W, Caglayan AB, Kilic E, et al. ​Inhibition of Fatty Acid Synthesis Aggravates Brain Injury, Reduces Blood-Brain Barrier Integrity and Impairs Neurological Recovery in a Murine Stroke Model​. ​​Frontiers in Cellular Neuroscience. ​2021;​15​. ​doi:10.3389/fncel.2021.733973. 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Maier IL, Schramm K, Bähr M, Behme D, Psychogios, Marios-Nikos, Liman J. ​Predictive Factors for the Need of Tracheostomy in Patients With Large Vessel Occlusion Stroke Being Treated With Mechanical Thrombectomy​. ​​Frontiers in Neurology. ​2021;​12​. ​doi:10.3389/fneur.2021.728624. 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Maass F, von Gottberg P, Franz J, Stadelmann C, Bähr M, Weber MS. ​Case Report: Findings Suggestive of Paraclinical Progressive Multifocal Leukoencephalopathy and Lung Cancer-Derived Brain Metastases in an MS Patient Treated With Fingolimod​. ​​Frontiers in Neurology. ​2021;​12​. ​doi:10.3389/fneur.2021.561158. 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Ribas VT, Vahsen BF, Tatenhorst L, Estrada V, Dambeck V, Almeida RA, et al. ​AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo​. ​​Cell Death & Disease. ​2021;​12​(2). ​doi:10.1038/s41419-021-03503-3. 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Maier IL, Leha A, Badr M, Allam I, Bähr M, Jamous A, et al. ​Inhouse Bridging Thrombolysis Is Associated With Improved Functional Outcome in Patients With Large Vessel Occlusion Stroke: Findings From the German Stroke Registry​. ​​Frontiers in Neurology. ​2021;​12​. ​doi:10.3389/fneur.2021.649108. 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Tatenhorst L, Caldi Gomes L, Zhang S, Parvaz M, Carboni E, Roser A, et al. ​Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrils​. ​​Journal of Neurochemistry. ​2021;​159​(3):​​554​-573​. ​doi:10.1111/jnc.15461. 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Saal KA, Warth Pérez Arias C, Roser A, Christoph Koch J, Bähr M, Rizzoli SO, et al. ​Rho‐kinase inhibition by fasudil modulates pre‐synaptic vesicle dynamics​. ​​Journal of Neurochemistry. ​2021;:​​n/a​-n/a​. ​doi:10.1111/jnc.15274. 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | 
    ​ ​Eisenberg HJ, Malinova V, Mielke D, Bähr M, Göricke MB, van Riesen C. ​ADCY5‐Induced Dyskinetic Storm Rescued with Pallidal Deep Brain Stimulation in a 46‐Year‐Old Man​. ​​Movement Disorders Clinical Practice. ​2020;:​​n/a​-n/a​. ​doi:10.1002/mdc3.13076. 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Haupt M, Zheng X, Kuang Y, Lieschke S, Janssen L, Bosche B, et al. ​Lithium modulates miR ‐1906 levels of mesenchymal stem cell‐derived extracellular vesicles contributing to poststroke neuroprotection by toll‐like receptor 4 regulation​. ​​STEM CELLS Translational Medicine. ​2020;​10​(3):​​357​-373​. ​doi:10.1002/sctm.20-0086. 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Maass F, Michalke B, Willkommen D, Schulte C, Tönges L, Boerger M, et al. ​Selenium speciation analysis in the cerebrospinal fluid of patients with Parkinson’s disease​. ​​Journal of Trace Elements in Medicine and Biology. ​2020;​57​:​​126412​. ​doi:10.1016/j.jtemb.2019.126412. 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Maass F, Michalke B, Willkommen D, Leha A, Schulte C, Tönges L, et al. ​Elemental fingerprint: Reassessment of a cerebrospinal fluid biomarker for Parkinson's disease​. ​​Neurobiology of Disease. ​2020;​134​:​​104677​. ​doi:10.1016/j.nbd.2019.104677. 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Maier IL, Hofer S, Eggert E, Schregel K, Psychogios, Marios-Nikos, Frahm J, et al. ​T1 Mapping Quantifies Spinal Cord Compression in Patients With Various Degrees of Cervical Spinal Canal Stenosis​. ​​Frontiers in Neurology. ​2020;​11​. ​doi:10.3389/fneur.2020.574604. 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Vahsen BF, Ribas VT, Sundermeyer J, Boecker A, Dambeck V, Lenz C, et al. ​Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing​. ​​Cell Death and Differentiation. ​2020;​27​(10):​​2810​-2827​. ​doi:10.1038/s41418-020-0543-y. 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Koch JC, Kuttler J, Maass F, Lengenfeld T, Zielke E, Bähr M, et al. ​Compassionate Use of the ROCK Inhibitor Fasudil in Three Patients With Amyotrophic Lateral Sclerosis​. ​​Frontiers in Neurology. ​2020;​11​. ​doi:10.3389/fneur.2020.00173. 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Kuang Y, Zheng X, Zhang L, Ai X, Venkataramani V, Kilic E, et al. ​Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25​. ​​Journal of Extracellular Vesicles. ​2020;​10​(1). ​doi:10.1002/jev2.12024. 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Ettelt P, Maier I, Schnieder M, Bähr M, Behme D, Psychogios, Marios-Nikos, et al. ​Bridging therapy is associated with improved cognitive function after large vessel occlusion stroke – an analysis of the German Stroke Registry​. ​​Neurological Research and Practice. ​2020;​2​(1). ​doi:10.1186/s42466-020-00079-9. 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Müller SJ, Khadhraoui E, Allam I, Argyriou L, Hehr U, Liman J, et al. ​CARASIL with coronary artery disease and distinct cerebral microhemorrhage: A case report and literature review​. ​​Clinical and Translational Neuroscience. ​2020;​4​(1):​​1​-5​. ​doi:10.1177/2514183X20914182. 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Maass F, Rikker S, Dambeck V, Warth C, Tatenhorst L, Csoti I, et al. ​Increased alpha-synuclein tear fluid levels in patients with Parkinson’s disease​. ​​Scientific Reports. ​2020;​10​(1). ​doi:10.1038/s41598-020-65503-1. 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Miloserdov K, Schmidt-Samoa C, Williams K, Weinrich CA, Kagan I, Bürk K, et al. ​Aberrant functional connectivity of resting state networks related to misperceptions and intra-individual variability in Parkinson‘s disease​. ​​NeuroImage: Clinical. ​2020;​25​:​​102076​. ​doi:10.1016/j.nicl.2019.102076. 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Lieschke S, Zechmeister B, Haupt M, Zheng X, Jin F, Hein K, et al. ​CCL11 Differentially Affects Post-Stroke Brain Injury and Neuroregeneration in Mice Depending on Age​. ​​Cells. ​2020;​9​(1):​​66​. ​doi:10.3390/cells9010066. 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Zheng X, Zhang L, Kuang Y, Venkataramani V, Jin F, Hein K, et al. ​Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice​. ​​Translational Stroke Research. ​2020;​12​(1):​​185​-203​. ​doi:10.1007/s12975-020-00814-z. 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Raina A, Leite K, Guerin S, Mahajani SU, Chakrabarti KS, Voll D, et al. ​Dopamine promotes the neurodegenerative potential of β‐synuclein​. ​​Journal of Neurochemistry. ​2020;​156​(5):​​674​-691​. ​doi:10.1111/jnc.15134. 
    ​Details  DOI  PMID  PMC 

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