Prof. Dr. Holger Stark

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  • 2021 | Journal Article | 
    ​ ​Structural insights into how Prp5 proofreads the pre-mRNA branch site​
    Zhang, Z.; Rigo, N.; Dybkov, O.; Fourmann, J.-B.; Will, C. L.; Kumar, V. & Urlaub, H.  et al.​ (2021) 
    Nature, 596(7871) pp. 296​-300​.​ DOI: https://doi.org/10.1038/s41586-021-03789-5 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome​
    Bertram, K.; El Ayoubi, L.; Dybkov, O.; Agafonov, D. E.; Will, C. L.; Hartmuth, K. & Urlaub, H.  et al.​ (2020) 
    Molecular Cell, 80(1) pp. 127​-139.e6​.​ DOI: https://doi.org/10.1016/j.molcel.2020.09.012 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Molecular architecture of the human 17S U2 snRNP​
    Zhang, Z.; Will, C. L.; Bertram, K.; Dybkov, O.; Hartmuth, K.; Agafonov, D. E. & Hofele, R. et al.​ (2020) 
    Nature, 583(7815) pp. 310​-313​.​ DOI: https://doi.org/10.1038/s41586-020-2344-3 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex​
    Haselbach, D.; Komarov, I.; Agafonov, D. E.; Hartmuth, K.; Graf, B.; Dybkov, O. & Urlaub, H.  et al.​ (2018) 
    Cell, 172(3) pp. 454​-464.e11​.​ DOI: https://doi.org/10.1016/j.cell.2018.01.010 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Protein-Cross-Linking zur Aufklärung von komplexen Strukturen​
    Dybkov, O.; Stützer, A.; Bertram, K.; Kastner, B.; Stark, H. ; Lührmann, R.   & Urlaub, H. ​ (2018) 
    BIOspektrum, 24(3) pp. 278​-282​.​ DOI: https://doi.org/10.1007/s12268-018-0909-6 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation​
    Bertram, K.; Agafonov, D. E.; Dybkov, O.; Haselbach, D.; Leelaram, M. N.; Will, C. L. & Urlaub, H.  et al.​ (2017) 
    Cell, 170(4) pp. 701​-713.e11​.​ DOI: https://doi.org/10.1016/j.cell.2017.07.011 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Cryo-EM structure of a human spliceosome activated for step 2 of splicing​
    Bertram, K.; Agafonov, D. E.; Liu, W.-T.; Dybkov, O.; Will, C. L.; Hartmuth, K. & Urlaub, H.  et al.​ (2017) 
    Nature, 542(7641) pp. 318​.​ DOI: https://doi.org/10.1038/nature21079 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Molecular architecture of the human U4/U6.U5 tri-snRNP​
    Agafonov, D. E.; Kastner, B.; Dybkov, O.; Hofele, R. V.; Liu, W.-T.; Urlaub, H.   & Lührmann, R.  et al.​ (2016) 
    Science, 351(6280) pp. 1416​-1420​.​ DOI: https://doi.org/10.1126/science.aad2085 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Molecular architecture of the Saccharomyces cerevisiae activated spliceosome​
    Rauhut, R.; Fabrizio, P.; Dybkov, O.; Hartmuth, K.; Pena, V.; Chari, A. & Kumar, V. et al.​ (2016) 
    Science, 353(6306) pp. 1399​-1405​.​ DOI: https://doi.org/10.1126/science.aag1906 
    ​Details  DOI  PMID  PMC  WoS 

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