Dr. Wiebke Möbius

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  • 2022 Journal Article | Research Paper | 
    ​ ​Heo D, Ling JP, Molina-Castro GC, Langseth AJ, Waisman A, Nave, Klaus-Armin, et al. ​Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43​. ​​eLife. ​2022;​11​. ​doi:10.7554/eLife.75230. 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper
    ​ ​Edgar JM, McGowan E, Chapple KJ, Möbius W, Lemgruber L, Insall RH, et al. ​Río‐Hortega's drawings revisited with fluorescent protein defines a cytoplasm‐filled channel system of CNS myelin​. ​​Journal of Anatomy. ​2021;​239​(6):​​1241​-1255​. ​doi:10.1111/joa.13577. 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Eichel MA, Gargareta, Vasiliki-Ilya, D’Este E, Fledrich R, Kungl T, Buscham TJ, et al. ​CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves​. ​​Nature Communications. ​2020;​11​(1). ​doi:10.1038/s41467-020-18172-7. 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Moore S, Meschkat M, Ruhwedel T, Trevisiol A, Tzvetanova ID, Battefeld A, et al. ​A role of oligodendrocytes in information processing​. ​​Nature Communications. ​2020;​11​(1). ​doi:10.1038/s41467-020-19152-7. 
    Details  DOI 
  • 2020 Journal Article | Research Paper | 
    ​ ​Trevisiol A, Kusch K, Steyer AM, Gregor I, Nardis C, Winkler U, et al. ​Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia​. ​​PLoS Biology. ​2020;​18​(11):​​e3000943​. ​doi:10.1371/journal.pbio.3000943. 
    Details  DOI 
  • 2020 Journal Article | Research Paper
    ​ ​Berghoff SA, Spieth L, Sun T, Hosang L, Schlaphoff L, Depp C, et al. ​Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis​. ​​Nature Neuroscience. ​2020;​24​(1):​​47​-60​. ​doi:10.1038/s41593-020-00757-6. 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper | 
    ​ ​Steyer AM, Ruhwedel T, Nardis C, Werner HB, Nave, Klaus-Armin, Möbius W. ​Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy​. ​​Journal of Structural Biology. ​2020;​210​(2):​​107492​. ​doi:10.1016/j.jsb.2020.107492. 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | 
    ​ ​Stumpf SK, Berghoff SA, Trevisiol A, Spieth L, Düking T, Schneider LV, et al. ​Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease​. ​​Acta Neuropathologica. ​2019;​138​(1):​​147​-161​. ​doi:10.1007/s00401-019-01985-2. 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | 
    ​ ​Erwig MS, Patzig J, Steyer AM, Dibaj P, Heilmann M, Heilmann I, et al. ​Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin​. ​​eLife. ​2019;​8​. ​doi:10.7554/eLife.43888. 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Weil, Marie-Theres, Heibeck S, Töpperwien M, tom Dieck S, Ruhwedel T, Salditt T, et al. ​Axonal Ensheathment in the Nervous System of Lamprey: Implications for the Evolution of Myelinating Glia​. ​​The Journal of Neuroscience. ​2018;​38​(29):​​6586​-6596​. ​doi:10.1523/JNEUROSCI.1034-18.2018. 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | 
    ​ ​Fledrich R, Abdelaal T, Rasch L, Bansal V, Schütza V, Brügger B, et al. ​Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy​. ​​Nature Communications. ​2018;​9​(1). ​doi:10.1038/s41467-018-05420-0. 
    Details  DOI 
  • 2018 Journal Article | Research Paper | 
    ​ ​Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, et al. ​Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity​. ​​eLife. ​2018;​7​. ​doi:10.7554/eLife.36428. 
    Details  DOI  PMID  PMC 
  • 2017 Conference Abstract
    ​ ​Kusch K, Uecker M, Liepold T, Möbius W, Werner HB, Valerius O, et al. ​SIRT2 as a genetic modifier of axonal degeneration in white matter tracts​. ​ 13th European Meeting on Glial Cells in Health and Disease; ​Edinburgh, Scotland. ​Glia. ​2017;​65​
    Details  WoS 
  • 2016 Journal Article | 
    ​ ​Poggi G, Boretius S, Möbius W, Moschny N, Baudewig J, Ruhwedel T, et al. ​Cortical network dysfunction caused by a subtle defect of myelination​. ​​Glia. ​2016;​64​(11):​​2025​-2040​. ​doi:10.1002/glia.23039. 
    Details  DOI 
  • 2016 Journal Article | Research Paper
    ​ ​Saab AS, Tzvetavona ID, Trevisiol A, Baltan S, Dibaj P, Kusch K, et al. ​Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism​. ​​Neuron. ​2016;​91​(1):​​119​-132​. ​doi:10.1016/j.neuron.2016.05.016. 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper
    ​ ​Werner HB, Kraemer-Albers, Eva-Maria, Strenzke N, Saher G, Tenzer S, Ohno-Iwashita Y, et al. ​A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system​. ​​Glia. ​2013;​61​(4):​​567​-586​. ​doi:10.1002/glia.22456. 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article | 
    ​ ​Fünfschilling U, Supplie LM, Mahad D, Boretius S, Saab AS, Edgar J, et al. ​Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity​. ​​Nature. ​2012;​485​(7397):​​517​-521​. ​doi:10.1038/nature11007. 
    Details  DOI 
  • 2007 Journal Article
    ​ ​Meyer zu Hörste G, Prukop T, Liebetanz D, Möbius W, Nave, Klaus-Armin, Sereda MW. ​Antiprogesterone therapy uncouples axonal loss from demyelination in a transgenic rat model of CMT1A neuropathy​. ​​Annals of Neurology. ​2007;​61​(1):​​61​-72​. ​doi:10.1002/ana.21026. 
    Details  DOI  WoS 

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