Prof. Dr. Elisabeth Zeisberg

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  • 2023 | Journal Article | 
    ​ ​Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis​
    Kanwischer, L.; Xu, X.; Saifuddin, A. B.; Maamari, S.; Tan, X.; Alnour, F. & Tampe, B. et al.​ (2023) 
    Clinical Epigenetics, 15(1) art. 149​.​ DOI: https://doi.org/10.1186/s13148-023-01561-2 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper | 
    ​ ​CRISPR/Cas Derivatives as Novel Gene Modulating Tools: Possibilities and In Vivo Applications​
    Xu, X.; Hulshoff, M. S.; Tan, X.; Zeisberg, M.   & Zeisberg, E. M. ​ (2020) 
    International Journal of Molecular Sciences, 21(9) pp. 3038​.​ DOI: https://doi.org/10.3390/ijms21093038 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper
    ​ ​Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1​
    Wilhelmi, T.; Xu, X.; Tan, X.; Hulshoff, M. S.; Maamari, S.; Sossalla, S.   & Zeisberg, M.  et al.​ (2020) 
    Theranostics, 10(9) pp. 3905​-3924​.​ DOI: https://doi.org/10.7150/thno.38640 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper | 
    ​ ​High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis​
    Xu, X.; Tan, X.; Tampe, B. ; Wilhelmi, T.; Hulshoff, M. S.; Saito, S. & Moser, T.  et al.​ (2018) 
    Nature Communications, 9(1) art. 3509​.​ DOI: https://doi.org/10.1038/s41467-018-05766-5 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article
    ​ ​Hypoxia-induced endothelial-mesenchymal transition is associated with RASAL1 promoter hypermethylation in human coronary endothelial cells​
    Xu, X.; Tan, X.; Hulshoff, M. S.; Wilhelmi, T.; Zeisberg, M.   & Zeisberg, E. M. ​ (2016) 
    FEBS Letters, 590(8) pp. 1222​-1233​.​ DOI: https://doi.org/10.1002/1873-3468.12158 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper | 
    ​ ​DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition​
    Tan, X.; Xu, X.; Zeisberg, M.   & Zeisberg, E. M. ​ (2016) 
    PLoS ONE, 11(1) art. e0147816​.​ DOI: https://doi.org/10.1371/journal.pone.0147816 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper
    ​ ​High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation​
    Tan, X.; Xu, X.; Zeisberg, E. M.   & Zeisberg, M. ​ (2016) 
    Biochemical and Biophysical Research Communications, 472(3) pp. 459​-464​.​ DOI: https://doi.org/10.1016/j.bbrc.2016.01.077 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Snail Is a Direct Target of Hypoxia-inducible Factor 1 alpha (HIF1 alpha) in Hypoxia-induced Endothelial to Mesenchymal Transition of Human Coronary Endothelial Cells​
    Xu, X.; Tan, X.; Tampe, B. ; Sanchez, E.; Zeisberg, M.   & Zeisberg, E. M. ​ (2015) 
    Journal of Biological Chemistry, 290(27) pp. 16653​-16664​.​ DOI: https://doi.org/10.1074/jbc.M115.636944 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis​
    Xu, X.; Tan, X.; Tampe, B. ; Nyamsuren, G.; Liu, X.; Maier, L. S.   & Sossalla, S.  et al.​ (2015) 
    Cardiovascular Research, 105(3) pp. 279​-291​.​ DOI: https://doi.org/10.1093/cvr/cvv015 
    ​Details  DOI  PMID  PMC  WoS 

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