Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes
2020 | journal article; research paper. A publication with affiliation to the University of Göttingen.
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Details
- Authors
- Kleinsorge, Mandy; Cyganek, Lukas
- Abstract
- The generation of homogeneous populations of subtype-specific cardiomyocytes derived from human induced pluripotent stem cells (hiPSCs) is crucial in cardiovascular disease modeling as well as in drug discovery and cardiotoxicity screenings. This protocol describes a simple, robust, and efficient monolayer-based differentiation of hiPSCs into defined atrial and ventricular cardiomyocytes. For complete details on the use and execution of this protocol, please refer to Cyganek et al., 2018.
- Issue Date
- 2020
- Journal
- STAR Protocols
- Project
- SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz
SFB 1002 | C04: Fibroblasten-Kardiomyozyten Interaktion im gesunden und erkrankten Herzen: Mechanismen und therapeutische Interventionen bei Kardiofibroblastopathien
SFB 1002 | S01: In vivo und in vitro Krankheitsmodelle - Working Group
- RG Cyganek (Stem Cell Unit)
- eISSN
- 2666-1667
- Language
- English
