UProC: tools for ultra-fast protein domain classification
2015 | journal article. A publication with affiliation to the University of Göttingen.
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Details
- Authors
- Meinicke, Peter
- Abstract
- Motivation: With rapidly increasing volumes of biological sequence data the functional analysis of new sequences in terms of similarities to known protein families challenges classical bioinformatics. Results: The ultrafast protein classification (UProC) toolbox implements a novel algorithm ('Mosaic Matching') for large-scale sequence analysis. UProC is by three orders of magnitude faster than profile-based methods and in a metagenome simulation study achieved up to 80% higher sensitivity on unassembled 100 bp reads.
- Issue Date
- 2015
- Status
- published
- Publisher
- Oxford Univ Press
- Journal
- Bioinformatics
- ISSN
- 1460-2059; 1367-4803
- Sponsor
- German Research Foundation (DFG) [ME 3138]