Biometrical Journal

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  • 2023 Journal Article
    ​ ​Friedrich, Sarah, and Tim Friede. "On the role of benchmarking data sets and simulations in method comparison studies​." ​Biometrical Journal (2023): ​2200212​. ​https://doi.org/10.1002/bimj.202200212.
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  • 2023 Journal Article
    ​ ​Friede, Tim. "Confidence intervals for discrete data in clinical research by VivekPradhan, Ashis K.Gangopadhyay, Sandeep M.Menon, CynthiaBasu, TathagataBanerjee.Boca Raton, FL: Chapman & Hall/CRC Press. 2022. 240 pages. ISBN: 9781138048980 (hbk). ISBN 9781315169859 (ebk). List price: £99.99​." ​Biometrical Journal (2023): ​2300026​. ​https://doi.org/10.1002/bimj.202300026.
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  • 2023 Journal Article
    ​ ​Gera, Roland G., and Tim Friede. "Blinded sample size recalculation in multiple composite population designs with normal data and baseline adjustments​." ​Biometrical Journal (2023): ​2000326​. ​https://doi.org/10.1002/bimj.202000326.
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  • 2023 Journal Article
    ​ ​Lado‐Baleato, Óscar, Carmen Cadarso‐Suárez, Thomas Kneib, and Francisco Gude. "Multivariate reference and tolerance regions based on conditional transformation models: Application to glycemic markers​." ​Biometrical Journal (2023): ​2200229​. ​https://doi.org/10.1002/bimj.202200229.
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  • 2022 Journal Article | 
    ​ ​Placzek, Marius, and Tim Friede. "Blinded sample size recalculation in adaptive enrichment designs​." ​Biometrical Journal ​65, no. 2 (2022): ​bimj.202000345​. ​https://doi.org/10.1002/bimj.202000345.
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  • 2022 Journal Article
    ​ ​Richter, Jakob, Tim Friede, and Jörg Rahnenführer. "Improving adaptive seamless designs through Bayesian optimization​." ​Biometrical Journal (2022): . ​https://doi.org/10.1002/bimj.202000389.
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  • 2022 Journal Article
    ​ ​Graf, Ricarda, Marina Zeldovich, and Sarah Friedrich. "Comparing linear discriminant analysis and supervised learning algorithms for binary classification—A method comparison study​." ​Biometrical Journal (2022): ​bimj.202200098​. ​https://doi.org/10.1002/bimj.202200098.
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  • 2022 Journal Article
    ​ ​Melis, Guadalupe Gómez, and Thomas Kneib. "In memory of Carmen María Cadarso Suárez (1960–2022)​." ​Biometrical Journal ​64, no. 7 (2022): ​1159​-1160​. ​https://doi.org/10.1002/bimj.202270075.
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  • 2021 Journal Article
    ​ ​Spiegel, Elmar, Thomas Kneib, Petra von Gablenz, and Fabian Otto‐Sobotka. "Generalized expectile regression with flexible response function​." ​Biometrical Journal (2021): . ​https://doi.org/10.1002/bimj.202000203.
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  • 2021 Journal Article
    ​ ​Kropf, Siegfried, Kai Antweiler, and Ekkehard Glimm. "Use of multivariate distance measures for high‐dimensional data in tests for difference, superiority, equivalence and non‐inferiority​." ​Biometrical Journal (2021): . ​https://doi.org/10.1002/bimj.202000367.
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  • 2021 Journal Article | 
    ​ ​Röver, Christian, and Tim Friede. "Bounds for the weight of external data in shrinkage estimation​." ​Biometrical Journal ​63, no. 5 (2021): ​1131​-1143​. ​https://doi.org/10.1002/bimj.202000227.
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  • 2021 Journal Article | 
    ​ ​Beyersmann, Jan, Tim Friede, and Claudia Schmoor. "Design aspects of COVID‐19 treatment trials: Improving probability and time of favorable events​." ​Biometrical Journal ​64, no. 3 (2021): ​440​-460​. ​https://doi.org/10.1002/bimj.202000359.
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  • 2020 Journal Article
    ​ ​Friede, Tim, Nigel Stallard, and Nicholas Parsons. "Adaptive seamless clinical trials using early outcomes for treatment or subgroup selection: Methods, simulation model and their implementation in R​." ​Biometrical Journal ​62, no. 5 (2020): ​1264​-1283​. ​https://doi.org/10.1002/bimj.201900020.
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  • 2020 Journal Article
    ​ ​Stegherr, Regina, Jan Beyersmann, Valentine Jehl, Kaspar Rufibach, Friedhelm Leverkus, Claudia Schmoor, and Tim Friede. "Survival analysis for AdVerse events with VarYing follow‐up times (SAVVY): Rationale and statistical concept of a meta‐analytic study​." ​Biometrical Journal ​63, no. 3 (2020): ​650​-670​. ​https://doi.org/10.1002/bimj.201900347.
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  • 2020 Journal Article
    ​ ​Ellenberger, David, Berthold Lausen, and Tim Friede. "Exact change point detection with improved power in small‐sample binomial sequences​." ​Biometrical Journal ​63, no. 3 (2020): ​558​-574​. ​https://doi.org/10.1002/bimj.201900273.
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  • 2020 Journal Article | 
    ​ ​Harden, Markus, and Tim Friede. "Sample size recalculation in multicenter randomized controlled clinical trials based on noncomparative data​." ​Biometrical Journal ​62, no. 5 (2020): ​1284​-1299​. ​https://doi.org/10.1002/bimj.201900138.
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  • 2019 Journal Article | 
    ​ ​Konietschke, Frank, Tim Friede, and Markus Pauly. "Semi‐parametric analysis of overdispersed count and metric data with varying follow‐up times: Asymptotic theory and small sample approximations​." ​Biometrical Journal ​61, no. 3 (2019): ​616​-629​. ​https://doi.org/10.1002/bimj.201800027.
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  • 2018 Journal Article | 
    ​ ​Röver, Christian, and Tim Friede. "Contribution to the discussion of "When should meta-analysis avoid making hidden normality assumptions?": A Bayesian perspective.​." ​Biometrical Journal (2018): . ​https://doi.org/10.1002/bimj.201800179.
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  • 2017 Journal Article | 
    ​ ​Friede, Tim, Christian Röver, Simon Wandel, and Beat Neuenschwander. "Meta-analysis of two studies in the presence of heterogeneity with applications in rare diseases.​." ​Biometrical journal. Biometrische Zeitschrift ​59, no. 4 (2017): ​658​-671​. ​https://doi.org/10.1002/bimj.201500236.
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  • 2017 Journal Article
    ​ ​Ursino, Moreno, Sarah Zohar, Frederike Lentz, Corinne Alberti, Tim Friede, Nigel Stallard, and Emmanuelle Comets. "Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations​." ​Biometrical Journal ​59, no. 4 (2017): ​804​-825​. ​https://doi.org/10.1002/bimj.201600084.
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  • 2017 Journal Article
    ​ ​Taylor-Robinson, David, Tania Pressler, Matthias Schmid, Andreas Mayr, Elisabeth Waldmann, Nadja Klein, and Thomas Kneib. "Boosting joint models for longitudinal and time-to-event data​." ​Biometrical Journal ​59, no. 6 (2017): ​1104-1121​-1121​. ​https://doi.org/10.1002/bimj.201600158.
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  • 2017 Journal Article
    ​ ​Wegscheider, Karl, and Tim Friede. "Do we consent to rules of consent and confidentiality?​." ​Biometrical Journal ​59, no. 2 (2017): ​235​-239​. ​https://doi.org/10.1002/bimj.201600150.
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  • 2017 Journal Article | 
    ​ ​Kunz, Cornelia Ursula, Nigel Stallard, Nicholas Parsons, Susan Todd, and Tim Friede. "Blinded versus unblinded estimation of a correlation coefficient to inform interim design adaptations​." ​Biometrical Journal ​59, no. 2 (2017): ​344​-357​. ​https://doi.org/10.1002/bimj.201500233.
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  • 2017 Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
    ​ ​Cadarso Suárez, Carmen, Nadja Klein, Thomas Kneib, Geert Molenberghs, and Dimitris Rizopoulos. "Editorial "Joint modeling of longitudinal and time-to-event data and beyond"​." ​Biometrical Journal ​59, no. 6 (2017): ​1101​-1103​. ​https://doi.org/10.1002/bimj.201700180.
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  • 2017 Journal Article
    ​ ​Duarte, Elisa, Bruno de Sousa, Carmen Cadarso-Suárez, Nadja Klein, Thomas Kneib, and Vítor Rodrigues. "Studying the relationship between a woman's reproductive lifespan and age at menarche using a Bayesian multivariate structured additive distributional regression model​." ​Biometrical journal. Biometrische Zeitschrift ​59, no. 6 (2017): ​1232​-1246​. ​https://doi.org/10.1002/bimj.201600245.
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  • 2016 Journal Article | 
    ​ ​Roever, Christian, Stefan Andreas, and Tim Friede. "Evidence synthesis for count distributions based on heterogeneous and incomplete aggregated data​." ​Biometrical Journal ​58, no. 1 (2016): ​170​-185​. ​https://doi.org/10.1002/bimj.201300288.
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  • 2016 Journal Article
    ​ ​Pauly, Markus, Thomas Asendorf, and Frank Konietschke. "Permutation-based inference for the AUC: A unified approach for continuous and discontinuous data​." ​Biometrical Journal ​58, no. 6 (2016): ​1319​-1337​. ​https://doi.org/10.1002/bimj.201500105.
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  • 2015 Journal Article
    ​ ​Michelot, Théo, Roland Langrock, Thomas Kneib, and Ruth King. "Maximum penalized likelihood estimation in semiparametric mark-recapture-recovery models​." ​Biometrical Journal ​58, no. 1 (2015): ​222​-239​. ​https://doi.org/10.1002/bimj.201400222.
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  • 2015 Review
    ​ ​Kneib, Thomas. "Applied Statistical Inference: Likelihood and Bayes. L.Held and D.Sabanés Bové (2014). Heidelberg: Springer. 376 pages, ISBN: 3642378862​," review of Applied Statistical Inference: Likelihood and Bayes. ​Biometrical Journal ​57​, no. 2​ (2015): ​362​-363​. ​https://doi.org/10.1002/bimj.201400209.
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  • 2014 Journal Article
    ​ ​Telschow, Fabian J. E., Stephan Huckemann, and Michael Pierrynowski. "Asymptotics for Object Descriptors​." ​Biometrical Journal ​56, no. 5 (2014): ​781​-785​. ​https://doi.org/10.1002/bimj.201300206.
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  • 2014 Journal Article
    ​ ​Duarte, Elisa, Bruno de Sousa, Carmen Cadarso-Suarez, Vitor Rodrigues, and Thomas Kneib. "Structured additive regression modeling of age of menarche and menopause in a breast cancer screening program​." ​Biometrical Journal ​56, no. 3 (2014): ​416​-427​. ​https://doi.org/10.1002/bimj.201200260.
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  • 2013 Journal Article
    ​ ​Hillmann, Julia, Thomas Kneib, Lena Koepcke, León M. Juárez Paz, and Jutta Kretzberg. "Bivariate cumulative probit model for the comparison of neuronal encoding hypotheses​." ​Biometrical Journal ​56, no. 1 (2013): ​23​-43​. ​https://doi.org/10.1002/bimj.201200161.
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  • 2013 Journal Article
    ​ ​Wenzel, Daniela, and Antonia Zapf. "Difference of two dependent sensitivities and specificities: Comparison of various approaches​." ​Biometrical Journal ​55, no. 5 (2013): ​705​-718​. ​https://doi.org/10.1002/bimj.201200186.
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  • 2013 Journal Article
    ​ ​Manitz, Juliane, and Michael Hoehle. "Bayesian outbreak detection algorithm for monitoring reported cases of campylobacteriosis in Germany​." ​Biometrical Journal ​55, no. 4 (2013): ​509​-526​. ​https://doi.org/10.1002/bimj.201200141.
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  • 2013 Journal Article
    ​ ​Schneider, Simon, Heinz Schmidli, and Tim Friede. "Blinded and unblinded internal pilot study designs for clinical trials with count data​." ​Biometrical Journal ​55, no. 4 (2013): ​617​-633​. ​https://doi.org/10.1002/bimj.201200189.
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  • 2012 Journal Article
    ​ ​Brunner, Edgar, Arne C. Bathke, and Marius Placzek. "Estimation of Box's e for low- and high-dimensional repeated measures designs with unequal covariance matrices​." ​Biometrical Journal ​54, no. 3 (2012): ​301​-316​. ​https://doi.org/10.1002/bimj.201100160.
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  • 2011 Journal Article
    ​ ​Porzelius, Christine, Marc Johannes, Harald Binder, and Tim Beißbarth. "Leveraging external knowledge on molecular interactions in classification methods for risk prediction of patients​." ​Biometrical Journal ​53, no. 2 (2011): ​190​-201​. ​https://doi.org/10.1002/bimj.201000155.
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  • 2009 Journal Article
    ​ ​Fröhlich, Holger, Achim Tresch, and Tim Beißbarth. "Nested effects models for learning signaling networks from perturbation data​." ​Biometrical Journal ​51, no. 2 (2009): ​304​-323​. ​https://doi.org/10.1002/bimj.200800185.
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  • 2009 Conference Paper
    ​ ​Bathke, Arne C., S. W. Harrar, and Mohiuddin Ahmad. "Some contributions to the analysis of multivariate data​." ​Biometrical Journal ​51​, ​no. 2 (2009): ​285​-303. https://doi.org/10.1002/bimj.200800196.
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  • 2007 Journal Article
    ​ ​Gillet, Elizabeth M.. "Qualified estimation of two measures of diversity within populations​." ​Biometrical Journal ​49, no. 2 (2007): ​272​-285​. ​https://doi.org/10.1002/bimj.200510303.
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  • 2005 Conference Paper
    ​ ​Freitag, G.. "Methods for assessing noninferiority with censored data​." ​Biometrical Journal ​47​, ​no. 1 (2005): ​88​-98. https://doi.org/10.1002/bimj.200410083.
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  • 2005 Journal Article | Letter Note
    ​ ​Munk, Axel, and H. J. Trampisch. "Therapeutic equivalence - Clinical issues and statistical methodology in noninferiority trials​." ​Biometrical Journal ​47, no. 1 (2005): ​7​-9​. ​https://doi.org/10.1002/bimj.200410093.
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  • 2005 Conference Paper
    ​ ​Lange, S., and G. Freitag. "Choice of delta: Requirements and reality - Results of a systematic review​." ​Biometrical Journal ​47​, ​no. 1 (2005): ​12​-27. https://doi.org/10.1002/bimj.200410085.
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  • 2004 Journal Article
    ​ ​Foraita, Ronja, Iris Pigeot, and Stephan Klasen. "P1.03: Revealing different structural components of malnutrition in Benin and Bangladesh by graphical chain models​." ​Biometrical Journal ​46, no. S1 (2004): ​97​-97​. ​https://doi.org/10.1002/bimj.200490152.
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  • 2004 Journal Article
    ​ ​Kneib, Thomas. "Penalized structured additive regression for space-time data​." ​Biometrical Journal ​46, no. S1 (2004): ​1​-1​. ​https://doi.org/10.1002/bimj.200490310.
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  • 2003 Journal Article
    ​ ​Gregorius, H. R., Elizabeth M. Gillet, and Martin Ziehe. "Measuring differences of trait distributions between populations​." ​Biometrical Journal ​45, no. 8 (2003): ​959​-973​. ​https://doi.org/10.1002/bimj.200390063.
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  • 2002 Journal Article
    ​ ​Munzel, U., and E. Brunner. "An exact paired rank test​." ​Biometrical Journal ​44, no. 5 (2002): ​584​-593​. ​https://doi.org/10.1002/1521-4036(200207)44:5<584::AID-BIMJ584>3.0.CO;2-9.
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  • 2000 Journal Article
    ​ ​Brunner, E., and U. Munzel. "The nonparametric Behrens-Fisher problem: Asymptotic theory and a small-sample approximation​." ​Biometrical Journal ​42, no. 1 (2000): ​17​-25​. ​https://doi.org/10.1002/(SICI)1521-4036(200001)42:1<17::AID-BIMJ17>3.0.CO;2-U.
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  • 2000 Journal Article
    ​ ​Munzel, U., and E. Brunner. "Nonparametric tests in the unbalanced multivariate one-way design​." ​Biometrical Journal ​42, no. 7 (2000): ​837​-854​. ​https://doi.org/10.1002/1521-4036(200011)42:7<837::AID-BIMJ837>3.0.CO;2-S.
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  • 2000 Journal Article
    ​ ​Brunner, E., and Frank Langer. "Nonparametric analysis of ordered categorical data in designs with longitudinal observations and small sample sizes​." ​Biometrical Journal ​42, no. 6 (2000): ​663​-675​. ​https://doi.org/10.1002/1521-4036(200010)42:6<663::AID-BIMJ663>3.0.CO;2-7.
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  • 2000 Journal Article | Research Paper
    ​ ​Munk, Axel, J. T. G. Hwang, and L. D. Brown. "Testing average equivalence - Finding a compromise between theory and practice​." ​Biometrical Journal ​42, no. 5 (2000): ​531​-551​. ​https://doi.org/10.1002/1521-4036(200009)42:5<531::AID-BIMJ531>3.0.CO;2-6.
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  • 1987 Journal Article
    ​ ​Heun, M., and H.-R. Gregorius. "A theoretical model for estimating linkage in F_2 populations with distorted single gene segregation​." ​Biometrical Journal ​29 (1987): ​397​-406​. ​
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  • 1984 Journal Article
    ​ ​Gregorius, H.-R.. "A Unique Genetic Distance​." ​Biometrical Journal ​26, no. 1 (1984): ​13​-18​. ​https://doi.org/10.1002/bimj.4710260103.
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  • 1979 Journal Article
    ​ ​Gregorius, H.-R.. "The Sensitivity of the Stationary Age Class Distribution o Changes in the Life History Components​." ​Biometrical Journal ​21, no. 6 (1979): ​565​-577​. ​https://doi.org/10.1002/bimj.4710210606.
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  • 1975 Journal Article
    ​ ​Gregorius, H.-R.. "Die Varianz der relativen Allelhäufigkeit in einer Population konstanter endlicher Größe​." ​Biometrical Journal ​17, no. 2 (1975): ​105​-116​. ​https://doi.org/10.1002/bimj.19750170206.
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