Prof. Dr. Mathias Bähr

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  • 2012 | Journal Article | Research Paper
    ​ ​Doeppner TR, Ewert TAS, Tönges L, Herz J, Zechariah A, Elali A, et al. ​Transduction of Neural Precursor Cells with TAT-Heat Shock Protein 70 Chaperone: Therapeutic Potential Against Ischemic Stroke after Intrastriatal and Systemic Transplantation​. ​​STEM CELLS. ​2012;​30​(6):​​1297​-1310​. ​doi:10.1002/stem.1098. 
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  • 2010 | Journal Article | Research Paper
    ​ ​Doeppner TR, El Aanbouri M, Dietz GPH, Weise J, Schwarting S, Bähr M. ​Transplantation of TAT-Bcl-x(L)-transduced neural precursor cells: Long-term neuroprotection after stroke​. ​​Neurobiology of Disease. ​2010;​40​(1):​​265​-276​. ​doi:10.1016/j.nbd.2010.05.033. 
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  • 2010 | Journal Article | Research Paper
    ​ ​Doeppner TR, Dietz GPH, Weise J, Bähr M. ​Protection of hippocampal neurogenesis by TAT-Bcl-x(L) after cerebral ischemia in mice​. ​​Experimental Neurology. ​2010;​223​(2):​​548​-556​. ​doi:10.1016/j.expneurol.2010.02.001. 
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  • 2009 | Journal Article | Research Paper
    ​ ​Nagel F, Bähr M, Dietz GPH. ​Tyrosine hydroxylase-positive amacrine interneurons in the mouse retina are resistant against the application of various parkinsonian toxins​. ​​Brain Research Bulletin. ​2009;​79​(5):​​303​-309​. ​doi:10.1016/j.brainresbull.2009.04.010 10.1016/j.brainresbull.2009.04.010. 
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  • 2009 | Journal Article | Research Paper
    ​ ​Doeppner TR, Nagel F, Dietz GPH, Weise J, Tönges L, Schwarting S, et al. ​TAT-Hsp70-mediated neuroprotection and increased survival of neuronal precursor cells after focal cerebral ischemia in mice​. ​​Journal of Cerebral Blood Flow & Metabolism. ​2009;​29​(6):​​1187​-1196​. ​doi:10.1038/jcbfm.2009.44. 
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  • 2009 | Journal Article
    ​ ​Doeppner TR, Dietz GPH, El Aanbouri M, Gerber J, Witte OW, Bähr M, et al. ​TAT-Bcl-X-L improves survival of neuronal precursor cells in the lesioned striatum after focal cerebral ischemia​. ​​Neurobiology of Disease. ​2009;​34​(1):​​87​-94​. ​doi:10.1016/j.nbd.2008.12.013. 
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  • 2009 | Journal Article | Research Paper
    ​ ​Bermel C, Tönges L, Planchamp V, Gillardon F, Weishaupt JH, Dietz GPH, et al. ​Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells​. ​​Molecular and Cellular Neuroscience. ​2009;​42​(4):​​427​-437​. ​doi:10.1016/j.mcn.2009.09.005. 
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  • 2008 | Journal Article
    ​ ​Nagel F, Dohm CP, Bähr M, Wouters FS, Dietz GP. ​Quantitative evaluation of chaperone activity and neuroprotection by different preparations of a cell-penetrating Hsp70​. ​​Journal of Neuroscience Methods. ​2008;​171​(2):​​226​-232​. ​doi:10.1016/j.jneumeth.2008.03.008. 
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  • 2008 | Journal Article | Research Paper
    ​ ​Shi H, Patschan D, Dietz GPH, Bähr M, Plotkin M, Goligorsky MS. ​Glial cell line-derived neurotrophic growth factor increases motility and survival of cultured mesenchymal stem cells and ameliorates acute kidney injury​. ​​AJP: Renal Physiology. ​2008;​294​(1):​​F229​-F235​. ​doi:10.1152/ajprenal.00386.2007. 
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  • 2008 | Journal Article | Research Paper
    ​ ​Dietz GPH, Stockhausen (née Peters) KV, Dietz B, Falkenburger BH, Valbuena P, Opazo F, et al. ​Membrane-permeable Bcl-x(L) prevents MPTP-induced dopaminergic neuronal loss in the substantia nigra​. ​​Journal of Neurochemistry. ​2008;​104​(3):​​757​-765​. ​doi:10.1111/j.1471-4159.2007.05028.x. 
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  • 2008 | Journal Article | Research Paper
    ​ ​Nagel F, Falkenburger BH, Tönges L, Kowsky S, Pöppelmeyer C, Schulz JB, et al. ​Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease​. ​​Journal of Neurochemistry. ​2008;​105​(3):​​853​-864​. ​doi:10.1111/j.1471-4159.2007.05204.x. 
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  • 2007 | Book Chapter
    ​ ​Dietz GPH, Bähr M. ​Synthesis of Cell-Penetrating Peptides and Their Application in Neurobiology​. ​In: Borsello T​, editor. ​Neuroprotection Methods and Protocols. ​Totowa, NJ: ​Humana Press; ​2007. p. 181​-198​. ​(Methods in Molecular Biology; vol. 399). doi:10.1007/978-1-59745-504-6_13. 
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  • 2007 | Journal Article | Research Paper
    ​ ​Dietz GPH, Dietz B, Bähr M. ​Bcl-X-L protects cerebellar granule neurons against the late phase, but not against the early phase of glutamate-induced cell death​. ​​Brain Research. ​2007;​1164​:​​136​-141​. ​doi:10.1016/j.brainres.2007.06.025. 
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  • 2007 | Journal Article | Research Paper
    ​ ​Peroni D, Negro A, Bähr M, Dietz GPH. ​Intracellular delivery of Neuroglobin using HIV-1 TAT protein transduction domain fails to protect against oxygen and glucose deprivation​. ​​Neuroscience Letters. ​2007;​421​(2):​​110​-114​. ​doi:10.1016/j.neulet.2007.05.046. 
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  • 2007 | Journal Article | Research Paper | 
    ​ ​Meuer K, Suppanz IE, Lingor P, Planchamp V, Göricke B, Fichtner L, et al. ​Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis​. ​​Cell Death and Differentiation. ​2007;​14​(4):​​651​-661​. ​doi:10.1038/sj.cdd.4402087. 
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  • 2006 | Journal Article | Research Paper
    ​ ​Dietz GPH, Valbuena PC, Dietz B, Meuer K, Müller P, Weishaupt JH, et al. ​Application of a blood-brain-barrier-penetrating form of GDNF in a mouse model for Parkinson's disease​. ​​Brain Research. ​2006;​1082​(1):​​61​-66​. ​doi:10.1016/j.brainres.2006.01.083. 
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  • 2006 | Journal Article | Research Paper
    ​ ​Hotchkiss RS, Mcconnell KW, Bullok K, Davis CG, Chang KC, Schwulst SJ, et al. ​TAT-BH4 and TAT-Bcl-x(L) peptides protect against sepsis-induced lymphocyte apoptosis in vivo​. ​​The journal of immunology. ​2006;​176​(9):​​5471​-5477​. ​doi:10.4049/jimmunol.176.9.5471. 
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  • 2006 | Journal Article | Research Paper
    ​ ​Meuer K, Pitzer C, Teismann P, Krüger C, Göricke B, Laage R, et al. ​Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson's disease​. ​​Journal of Neurochemistry. ​2006;​97​(3):​​675​-686​. ​doi:10.1111/j.1471-4159.2006.03727.x. 
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  • 2006 | Journal Article | Research Paper
    ​ ​Tönges L, Lingor P, Egle R, Dietz GPH, Fahr A, Bähr M. ​Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons​. ​​RNA. ​2006;​12​(7):​​1431​-1438​. ​doi:10.1261/rna.2252206. 
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  • 2006 | Journal Article | Research Paper
    ​ ​Dietz GPH, Dietz B, Bähr M. ​Bcl-XL increases axonal numbers but not axonal elongation from rat retinal explants​. ​​Brain Research Bulletin. ​2006;​70​(2):​​117​-123​. ​doi:10.1016/j.brainresbull.2006.03.022. 
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  • 2006 | Journal Article | Research Paper
    ​ ​Guegan C, Braudeau J, Couriaud C, Dietz GPH, Lacombe P, Bähr M, et al. ​PTD-XIAP protects against cerebral ischemia by anti-apoptotic and transcriptional regulatory mechanisms​. ​​Neurobiology of Disease. ​2006;​22​(1):​​177​-186​. ​doi:10.1016/j.nbd.2005.10.014. 
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  • 2005 | Journal Article | Research Paper
    ​ ​Dietz GPH, Schott M, Labes M, Bähr M. ​Expression of the protein inhibitor of nitric oxide synthase in the adult rat retina before and after optic nerve lesion​. ​​Molecular Brain Research. ​2005;​136​(1-2):​​118​-124​. ​doi:10.1016/j.molbrainres.2005.01.011. 
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  • 2005 | Journal Article | Research Paper
    ​ ​Diem R, Taheri N, Dietz GPH, Kuhnert AV, Maier K, Sattler M, et al. ​HIV-tat-mediated BCl-X-L delivery protects retinal ganglion cells during experimental autoimmune optic neuritis​. ​​Neurobiology of Disease. ​2005;​20​(2):​​218​-226​. ​doi:10.1016/j.nbd.2005.03.003. 
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  • 2005 | Journal Article | Research Paper
    ​ ​Dietz GPH, Bähr M. ​Peptide-enhanced cellular internalization of proteins in neuroscience​. ​​Brain Research Bulletin. ​2005;​68​(1-2):​​103​-114​. ​doi:10.1016/j.brainresbull.2005.08.015. 
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  • 2005 | Journal Article | Research Paper | 
    ​ ​Pizzi M, Sarnico I, Boroni F, Benarese M, Steimberg N, Mazzoleni G, et al. ​NF-kappa B factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity​. ​​Cell Death and Differentiation. ​2005;​12​(7):​​761​-772​. ​doi:10.1038/sj.cdd.4401598 10.1038/sj.cdd.4401742. 
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  • 2005 | Journal Article | Research Paper
    ​ ​Ebert S, Dietz GPH, Mitchell TJ, Michel U, Bähr M, Nau R. ​Limited protection of TAT-Bcl-X-L against pneumolysin-induced neuronal cell death​. ​​Neuroscience Letters. ​2005;​384​(3):​​349​-353​. ​doi:10.1016/j.neulet.2005.05.027. 
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  • 2004 | Journal Article | Research Paper | 
    ​ ​Kilic U, Kilic E, Dietz GPH, Bähr M. ​The TAT Protein Transduction Domain Enhances the Neuroprotective Effect of Glial-Cell-Line-Derived Neurotrophic Factor after Optic Nerve Transection​. ​​Neurodegenerative Diseases. ​2004;​1​(1):​​44​-49​. ​doi:10.1159/000076669. 
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  • 2004 | Review
    ​ ​Dietz GPH, Bähr M. ​Delivery of bioactive molecules into the cell: The Trojan horse approach​ [book review]. ​​Molecular and Cellular Neuroscience. ​2004;​27​(2):​​85​-131​. ​doi:10.1016/j.mcn.2004.03.005. 
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  • 2003 | Journal Article | Research Paper
    ​ ​Kilic U, Kilic E, Dietz GPH, Bähr M. ​Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice​. ​​Stroke. ​2003;​34​(5):​​1304​-1310​. ​doi:10.1161/01.STR.0000066869.45310.50. 
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  • 2002 | Journal Article | Research Paper
    ​ ​Kilic E, Dietz GPH, Hermann DM, Bähr M. ​Intravenous TAT-Bcl-XL is protective after middle cerebral artery occlusion in mice​. ​​Annals of Neurology. ​2002;​52​(5):​​617​-622​. ​doi:10.1002/ana.10356. 
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  • 2002 | Journal Article | Research Paper
    ​ ​Dietz GPH, Kilic E, Bähr M. ​Inhibition of neuronal apoptosis in vitro and in vivo using TAT-Mediated protein transduction​. ​​Molecular and Cellular Neuroscience. ​2002;​21​(1):​​29​-37​. ​doi:10.1006/mcne.2002.1165. 
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