Prof. Dr. Wolfram-Hubertus Zimmermann

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  • 2022 | Journal Article | Research Paper
    ​ ​Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissues​
    Santos, G. L.; DeGrave, A. N.; Rehman, A.; Al Disi, S.; Xhaxho, K.; Schröder, H. & Bao, G. et al.​ (2022) 
    Biomaterials Advances, 139 art. 213041​.​ DOI: https://doi.org/10.1016/j.bioadv.2022.213041 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Modulating the Biomechanical Properties of Engineered Connective Tissues by Chitosan-Coated Multiwall Carbon Nanotubes​
    Kittana, N.; Assali, M.; Zimmermann, W.-H. ; Liaw, N. ; Santos, G. L. ; Rehman, A. & Lutz, S. ​ (2021) 
    International Journal of Nanomedicine, Volume 16 pp. 989​-1000​.​ DOI: https://doi.org/10.2147/IJN.S289107 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper
    ​ ​Fibroblast Derived Human Engineered Connective Tissue for Screening Applications​
    Santos, G. L.; Meyer, T. ; Tiburcy, M. ; DeGrave, A.; Zimmermann, W.-H.   & Lutz, S. ​ (2021) 
    Journal of Visualized Experiments,(174).​ DOI: https://doi.org/10.3791/62700 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article
    ​ ​Mechanistic role of the CREB-regulated transcription coactivator 1 in cardiac hypertrophy​
    Morhenn, K.; Quentin, T.; Wichmann, H.; Steinmetz, M. ; Prondzynski, M.; Söhren, K.-D. & Christ, T. et al.​ (2019) 
    Journal of Molecular and Cellular Cardiology, 127 pp. 31​-43​.​ DOI: https://doi.org/10.1016/j.yjmcc.2018.12.001 
    ​Details  DOI 
  • 2019 | Journal Article | Research Paper | 
    ​ ​Inhibition of Rho-associated kinases suppresses cardiac myofibroblast function in engineered connective and heart muscle tissues​
    Santos, G. L. ; Hartmann, S.; Zimmermann, W.-H. ; Ridley, A. & Lutz, S. ​ (2019) 
    Journal of Molecular and Cellular Cardiology, 134 pp. 13​-28​.​ DOI: https://doi.org/10.1016/j.yjmcc.2019.06.015 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper
    ​ ​Sex-specific regulation of collagen I and III expression by 17β-Estradiol in cardiac fibroblasts: role of estrogen receptors​
    Dworatzek, E.; Mahmoodzadeh, S.; Schriever, C.; Kusumoto, K.; Kramer, L.; Santos, G.   & Fliegner, D. et al.​ (2018) 
    Cardiovascular Research, 115(2) pp. 315​-327​.​ DOI: https://doi.org/10.1093/cvr/cvy185 
    ​Details  DOI 
  • 2015 | Journal Article | Research Paper | 
    ​ ​RhoA Ambivalently Controls Prominent Myofibroblast Characteritics by Involving Distinct Signaling Routes​
    Jatho, A. ; Hartmann, S.; Kittana, N.; Muegge, F.; Wuertz, C. M. ; Tiburcy, M.   & Zimmermann, W.-H.  et al.​ (2015) 
    PLoS ONE, 10(10) art. e0137519​.​ DOI: https://doi.org/10.1371/journal.pone.0137519 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​p63RhoGEF regulates auto- and paracrine signaling in cardiac fibroblasts​
    Ongherth, A.; Pasch, S.; Wuertz, C. M. ; Nowak, K.; Kittana, N.; Weis, C. A. & Jatho, A.  et al.​ (2015) 
    Journal of Molecular and Cellular Cardiology, 88 pp. 39​-54​.​ DOI: https://doi.org/10.1016/j.yjmcc.2015.09.009 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways​
    Vettel, C. ; Lämmle, S.; Ewens, S.; Cervirgen, C.; Emmons, J.; Ongherth, A. & Dewenter, M.  et al.​ (2014) 
    American Journal of Physiology - Heart and Circulatory Physiology, 306(8) pp. H1246​-H1252​.​ DOI: https://doi.org/10.1152/ajpheart.00852.2013 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Research Paper
    ​ ​Phosphodiesterase-2 Is Up-Regulated in Human Failing Hearts and Blunts β-Adrenergic Responses in Cardiomyocytes​
    Mehel, H.; Emons, J.; Vettel, C. ; Wittköpper, K.; Seppelt, D.; Dewenter, M.   & Lutz, S.  et al.​ (2013) 
    Journal of the American College of Cardiology, 62(17) pp. 1596​-1606​.​ DOI: https://doi.org/10.1016/j.jacc.2013.05.057 
    ​Details  DOI  PMID  PMC  WoS 

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