Prof. Dr. Wolfram-Hubertus Zimmermann

 
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  • 2023 Preprint
    ​ ​LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome​
    Busley, A. V.; Gutiérrez-Gutiérrez, Ó.; Hammer, E.; Steinegger, M.; Böhmer, L.; Schroeder, H.& Kleinsorge, M. et al.​ (2023). DOI: https://doi.org/10.1101/2023.01.10.523203 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Somatic mosaicism in STAG2-associated cohesinopathies: Expansion of the genotypic and phenotypic spectrum​
    Schmidt, J. ; Dreha-Kulaczewski, S. ; Zafeiriou, M. P. ; Schreiber, M.-K.; Wilken, B.; Funke, R. & Neuhofer, C. M. et al.​ (2022) 
    Frontiers in Cell and Developmental Biology10.​ DOI: https://doi.org/10.3389/fcell.2022.1025332 
    Details  DOI  PMID  PMC 
  • 2022 Journal Article | Research Paper
    ​ ​Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissues​
    Santos, G. L.; DeGrave, A. N.; Rehman, A.; Al Disi, S.; Xhaxho, K.; Schröder, H. & Bao, G. et al.​ (2022) 
    Biomaterials Advances139 art. 213041​.​ DOI: https://doi.org/10.1016/j.bioadv.2022.213041 
    Details  DOI  PMID  PMC 
  • 2022 Journal Article | Research Paper | 
    ​ ​Impact of Immunosuppressive Drugs on Fibroblasts: An In Vitro Study​
    Wagner, G.; Sievers, L.; Tiburcy, M. ; Zimmermann, W.-H. ; Kollmar, O. ; Schmalz, G. & Ziebolz, D.​ (2022) 
    Journal of Clinical Medicine11(11).​ DOI: https://doi.org/10.3390/jcm11113107 
    Details  DOI 
  • 2022 Journal Article | Research Paper
    ​ ​Transmural myocardial repair with engineered heart muscle in a rat model of heterotopic heart transplantation - A proof-of-concept study​
    Jebran, A.-F.; Tiburcy, M.; Biermann, D.; Balfanz, P.; Didié, M.; Karikkineth, B. C. & Schöndube, F. et al.​ (2022) 
    Journal of Molecular and Cellular Cardiology,.​ DOI: https://doi.org/10.1016/j.yjmcc.2022.03.013 
    Details  DOI  PMID  PMC 
  • 2022 Journal Article | Research Paper
    ​ ​Modulatorische Einheiten bei Herzinsuffizienz​
    Hasenfuß, G. P. ; Kaul, A.; Lehnart, S. E. ; Linke, W. A. ; Zelarayan, L. C.   & Zimmermann, W.-H. ​ (2022) 
    Der Kardiologe16(2) pp. 109​-114​.​ DOI: https://doi.org/10.1007/s12181-022-00540-w 
    Details  DOI 
  • 2022 Journal Article | Overview
    ​ ​Remote control of the heart and beyond​
    Zimmermann, W.-H. ​ (2022) 
    Science376(6596) pp. 917​-918​.​ DOI: https://doi.org/10.1126/science.abq0605 
    Details  DOI  PMID  PMC 
  • 2022 Preprint
    ​ ​Dystrophin is a mechanical tension modulator​
    Hofemeier, A. D.; Muenker, T. M.; Herkenrath, F.; Ristau, M.; Brandt, M.; Shahriyari, M.& Tiburcy, M. et al.​ (2022). DOI: https://doi.org/10.1101/2022.12.23.521750 
    Details  DOI 
  • 2021 Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
    ​ ​Editorial commentary: Challenges to heart repair with pluripotent stem cell-derived cardiomyocytes​
    Zimmermann, W.-H. ​ (2021) 
    Trends in Cardiovascular Medicine31(2) pp. 91​-92​.​ DOI: https://doi.org/10.1016/j.tcm.2020.03.006 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper
    ​ ​Modulating the Biomechanical Properties of Engineered Connective Tissues by Chitosan-Coated Multiwall Carbon Nanotubes [Corrigendum]​
    Kittana, N.; Assali, M.; Zimmermann, W.-H. ; Liaw, N.; Santos, G. L.; Rehman, A. & Lutz, S.​ (2021) 
    International Journal of NanomedicineVolume 16 pp. 6427​-6428​.​ DOI: https://doi.org/10.2147/IJN.S339659 
    Details  DOI 
  • 2021 Preprint
    ​ ​Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity​
    Shahriyari, M.; Islam, M. R.; Sakib, M. S.; Rika, A.; Krüger, D.; Kaurani, L.& Anandakumar, H. et al.​ (2021). DOI: https://doi.org/10.1101/2021.07.12.452030 
    Details  DOI 
  • 2021 Journal Article
    ​ ​Basic and Translational Research in Cardiac Repair and Regeneration​
    Zhang, J.; Bolli, R.; Garry, D. J.; Marbán, E.; Menasché, P.; Zimmermann, W.-H.   & Kamp, T. J. et al.​ (2021) 
    Journal of the American College of Cardiology78(21) pp. 2092​-2105​.​ DOI: https://doi.org/10.1016/j.jacc.2021.09.019 
    Details  DOI 
  • 2021 Journal Article
    ​ ​Regenerative potential of epicardium-derived extracellular vesicles mediated by conserved miRNA transfer​
    del Campo, C. V.; Liaw, N. Y.; Gunadasa-Rohling, M.; Matthaei, M.; Braga, L.; Kennedy, T. & Salinas, G. et al.​ (2021) 
    Cardiovascular Research118(2) pp. 597​-611​.​ DOI: https://doi.org/10.1093/cvr/cvab054 
    Details  DOI 
  • 2021 Journal Article
    ​ ​Abstract MP217: Nuclease-deficient Cas9 Transcription Factors Restore Krueppel-like Factor 15 Expression In Stressed Mouse And Human Cardiomyocytes​
    Schoger, E.; Rosa, K.; Rocha, C.; Jassyk, M.; Doroudgar, S.; Mueller, O. & Cyganek, L.  et al.​ (2021) 
    Circulation Research129(Suppl_1).​ DOI: https://doi.org/10.1161/res.129.suppl_1.MP217 
    Details  DOI 
  • 2021 Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
    ​ ​Multiscale Strategy to Resolve Stroma–Cardiac Fibroblast Interactions​
    Zimmermann, W.-H. ​ (2021) 
    Circulation Research128(1) pp. 39​-41​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.120.318494 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​Modulating the Biomechanical Properties of Engineered Connective Tissues by Chitosan-Coated Multiwall Carbon Nanotubes​
    Kittana, N.; Assali, M.; Zimmermann, W.-H. ; Liaw, N. ; Santos, G. L. ; Rehman, A. & Lutz, S. ​ (2021) 
    International Journal of NanomedicineVolume 16 pp. 989​-1000​.​ DOI: https://doi.org/10.2147/IJN.S289107 
    Details  DOI 
  • 2021 Journal Article | 
    ​ ​Cell programming to protect the ischemic heart and limb​
    Brittan, M. & Zimmermann, W.-H. ​ (2021) 
    Molecular Therapy,.​ DOI: https://doi.org/10.1016/j.ymthe.2021.09.007 
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  • 2021 Journal Article | Research Paper
    ​ ​Fibroblast Derived Human Engineered Connective Tissue for Screening Applications​
    Santos, G. L.; Meyer, T. ; Tiburcy, M. ; DeGrave, A.; Zimmermann, W.-H.   & Lutz, S. ​ (2021) 
    Journal of Visualized Experiments,(174).​ DOI: https://doi.org/10.3791/62700 
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  • 2021 Journal Article | Research Paper | 
    ​ ​Chalcone‐Supported Cardiac Mesoderm Induction in Human Pluripotent Stem Cells for Heart Muscle Engineering​
    Raad, F. S. ; Khan, T. A. ; Esser, T. U.; Hudson, J. E. ; Seth, B. I.; Fujita, B.   & Gandamala, R. et al.​ (2021) 
    ChemMedChem16(21) art. cmdc.202100222​.​ DOI: https://doi.org/10.1002/cmdc.202100222 
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  • 2021 Journal Article | Research Paper
    ​ ​Organs-on-chip models for cardiovascular drug development​
    Zimmermann, W.-H. ​ (2021) 
    Cardiovascular Research117(12) pp. e164​-e165​.​ DOI: https://doi.org/10.1093/cvr/cvab229 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​A microRNA signature that correlates with cognition and is a target against cognitive decline​
    Islam, M. R.; Kaurani, L.; Berulava, T.; Heilbronner, U.; Budde, M.; Centeno, T. P. & Elerdashvili, V. et al.​ (2021) 
    EMBO Molecular Medicine13(11).​ DOI: https://doi.org/10.15252/emmm.202013659 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression​
    Schoger, E.; Zimmermann, W.-H. ; Cyganek, L.   & Zelarayán, L. C. ​ (2021) 
    Stem Cell Research55 art. S1873506121003202​.​ DOI: https://doi.org/10.1016/j.scr.2021.102473 
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  • 2021 Journal Article | Research Paper | 
    ​ ​Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation​
    Schoger, E.; Zimmermann, W.-H. ; Cyganek, L.   & Zelarayán, L. C. ​ (2021) 
    Stem Cell Research56 art. S1873506121003652​.​ DOI: https://doi.org/10.1016/j.scr.2021.102518 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Overview
    ​ ​Tissue engineered heart repair from preclinical models to first-in-patient studies​
    Zimmermann, W.-H. ​ (2020) 
    Current Opinion in Physiology14 pp. 70​-77​.​ DOI: https://doi.org/10.1016/j.cophys.2020.02.001 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Cardiovascular molecular mechanisms of disease with COVID-19​
    Foo, R.; Wang, Y.; Zimmermann, W.-H. ; Backs, J. & Wang, D. W.​ (2020) 
    Journal of Molecular and Cellular Cardiology141 pp. 107​.​ DOI: https://doi.org/10.1016/j.yjmcc.2020.04.010 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​Non-Human Primate iPSC Generation, Cultivation, and Cardiac Differentiation under Chemically Defined Conditions​
    Stauske, M.; Rodriguez Polo, I.; Haas, W.; Knorr, D. Y.; Borchert, T. ; Streckfuss-Bömeke, K.   & Dressel, R.  et al.​ (2020) 
    Cells9(6) pp. 1349​.​ DOI: https://doi.org/10.3390/cells9061349 
    Details  DOI 
  • 2020 Journal Article | Research Paper
    ​ ​19th Annual Meeting of the Safety Pharmacology Society: regulatory and safety perspectives for advanced therapy medicinal products (cellular and gene therapy products)​
    Cavero, I.; Seimetz, D.; Koziel, D.; Zimmermann, W.-H.   & Holzgrefe, H. H.​ (2020) 
    Expert Opinion on Drug Safety19(5) pp. 553​-558​.​ DOI: https://doi.org/10.1080/14740338.2020.1741546 
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  • 2020 Journal Article | Research Paper | 
    ​ ​Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation​
    Schoger, E.; Argyriou, L.; Zimmermann, W.-H. ; Cyganek, L.   & Zelarayán, L. C. ​ (2020) 
    Stem Cell Research48 pp. 101944​.​ DOI: https://doi.org/10.1016/j.scr.2020.101944 
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  • 2020 Journal Article | Research Paper | 
    ​ ​Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice​
    Zheng, X.; Zhang, L.; Kuang, Y.; Venkataramani, V. ; Jin, F.; Hein, K. & Zafeiriou, M. P.  et al.​ (2020) 
    Translational Stroke Research12(1) pp. 185​-203​.​ DOI: https://doi.org/10.1007/s12975-020-00814-z 
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  • 2020 Journal Article | Research Paper | 
    ​ ​Generation of Engineered Human Myocardium in a Multi-well Format​
    Tiburcy, M. ; Meyer, T. ; Liaw, N. Y. & Zimmermann, W.-H. ​ (2020) 
    STAR Protocols1(1) art. 100032​.​ DOI: https://doi.org/10.1016/j.xpro.2020.100032 
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  • 2020 Journal Article | Research Paper | 
    ​ ​Troponin destabilization impairs sarcomere-cytoskeleton interactions in iPSC-derived cardiomyocytes from dilated cardiomyopathy patients​
    Dai, Y.; Amenov, A.; Ignatyeva, N.; Koschinski, A.; Xu, H.; Soong, P. L.   & Tiburcy, M.  et al.​ (2020) 
    Scientific Reports10(1) art. 209​.​ DOI: https://doi.org/10.1038/s41598-019-56597-3 
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  • 2020 Journal Article | Research Paper
    ​ ​Inhibition of Prolyl-Hydroxylase Domain Enzymes Protects From Reoxygenation Injury in Engineered Human Myocardium​
    Levent, E. ; Noack, C. ; Zelarayán, L. C. ; Katschinski, D. M. ; Zimmermann, W.-H.   & Tiburcy, M. ​ (2020) 
    Circulation142(17) pp. 1694​-1696​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.119.044471 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper
    ​ ​Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome–Associated Cardiomyopathy​
    Hanses, U.; Kleinsorge, M.; Roos, L.; Yigit, G. ; Li, Y. ; Barbarics, B. & El-Battrawy, I. et al.​ (2020) 
    Circulation142(11) pp. 1059​-1076​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.119.044794 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper
    ​ ​Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide​
    Montiel, V.; Bella, R.; Michel, L. Y. M.; Esfahani, H.; De Mulder, D.; Robinson, E. L. & Deglasse, J.-P. et al.​ (2020) 
    Science Translational Medicine12(564) art. eaay2176​.​ DOI: https://doi.org/10.1126/scitranslmed.aay2176 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper
    ​ ​CRISPR-Mediated Activation of Endogenous Gene Expression in the Postnatal Heart​
    Schoger, E.; Carroll, K. J.; Iyer, L. M. ; McAnally, J. R.; Tan, W.; Liu, N. & Noack, C.  et al.​ (2020) 
    Circulation Research126(1) pp. 6​-24​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.118.314522 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper | 
    ​ ​Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids​
    Zafeiriou, M.-P. ; Bao, G. ; Hudson, J. ; Halder, R. ; Blenkle, A.; Schreiber, M.-K. & Fischer, A.  et al.​ (2020) 
    Nature Communications11(1).​ DOI: https://doi.org/10.1038/s41467-020-17521-w 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Research Paper | 
    ​ ​X-ray diffraction imaging of cardiac cells and tissue​
    Nicolas, J.-D.; Bernhardt, M.; Schlick, S. F. ; Tiburcy, M. ; Zimmermann, W.-H. ; Khan, A. & Markus, A.  et al.​ (2019) 
    Progress in Biophysics and Molecular Biology144 pp. 151​-165​.​ DOI: https://doi.org/10.1016/j.pbiomolbio.2018.05.012 
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  • 2019 Journal Article
    ​ ​Physics meets medicine - At the heart of active matter​
    Tarantola, M. ; Meyer, T. ; Schmidt, C. F.   & Zimmermann, W.-H. ​ (2019) 
    Progress in Biophysics and Molecular Biology144 pp. 1​-2​.​ DOI: https://doi.org/10.1016/j.pbiomolbio.2019.03.009 
    Details  DOI 
  • 2019 Journal Article
    ​ ​A Cardiac α-Actin (Actc1) Gene Mutation Causes Atrial-Septal Defects Associated with Dilated Cardiomyopathy​
    Frank, D.; Rangrez, A. Y.; Friedrich, C.; Dittmann, S.; Stallmeyer, B.; Yadav, P. & Bernt, A. et al.​ (2019) 
    Journal of the American College of Cardiology73(9) pp. 963​.​ DOI: https://doi.org/10.1016/S0735-1097(19)31570-0 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Mechanistic role of the CREB-regulated transcription coactivator 1 in cardiac hypertrophy​
    Morhenn, K.; Quentin, T.; Wichmann, H.; Steinmetz, M. ; Prondzynski, M.; Söhren, K.-D. & Christ, T. et al.​ (2019) 
    Journal of Molecular and Cellular Cardiology127 pp. 31​-43​.​ DOI: https://doi.org/10.1016/j.yjmcc.2018.12.001 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Cardiac α-Actin ( ACTC1 ) Gene Mutation Causes Atrial-Septal Defects Associated With Late-Onset Dilated Cardiomyopathy​
    Frank, D.; Rangrez, A. Y.; Friedrich, C.; Dittmann, S.; Stallmeyer, B.; Yadav, P. & Bernt, A. et al.​ (2019) 
    Circulation: Genomic and Precision Medicine12(8).​ DOI: https://doi.org/10.1161/CIRCGEN.119.002491 
    Details  DOI 
  • 2019 Journal Article | Overview
    ​ ​ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure​
    Madonna, R.; Van Laake, L. W; Botker, H. E.; Davidson, S. M; De Caterina, R.; Engel, F. B & Eschenhagen, T.  et al.​ (2019) 
    Cardiovascular Research115(3) pp. 488​-500​.​ DOI: https://doi.org/10.1093/cvr/cvz010 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Research Paper | 
    ​ ​Serum of patients with acute myocardial infarction prevents inflammation in iPSC-cardiomyocytes​
    Sattler, K.; El-Battrawy, I.; Zhao, Z.; Schrottenberg, C.; Yücel, G.; Lan, H. & Li, X. et al.​ (2019) 
    Scientific Reports9(1) art. 5651​.​ DOI: https://doi.org/10.1038/s41598-019-42079-z 
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  • 2019 Journal Article | Research Paper | 
    ​ ​Agonistic and antagonistic roles of fibroblasts and cardiomyocytes on viscoelastic stiffening of engineered human myocardium​
    Schlick, S. F. ; Spreckelsen, F.; Tiburcy, M. ; Iyer, L. M. ; Meyer, T. ; Zelarayan, L. C.   & Luther, S.  et al.​ (2019) 
    Progress in Biophysics and Molecular Biology144 pp. 51​-60​.​ DOI: https://doi.org/10.1016/j.pbiomolbio.2018.11.011 
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  • 2019 Journal Article | Research Paper
    ​ ​A cellular model of Brugada syndrome with SCN10A variants using human-induced pluripotent stem cell-derived cardiomyocytes​
    El-Battrawy, I.; Albers, S.; Cyganek, L. ; Zhao, Z.; Lan, H.; Li, X. & Xu, Q. et al.​ (2019) 
    Europace21(9) pp. 1410​-1421​.​ DOI: https://doi.org/10.1093/europace/euz122 
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  • 2019 Journal Article | 
    ​ ​Regeneration competent satellite cell niches in rat engineered skeletal muscle​
    Tiburcy, M. ; Markov, A.; Kraemer, L. K.; Christalla, P.; Rave-Fränk, M. ; Fischer, H. J.   & Reichardt, H. M.  et al.​ (2019) 
    FASEB BioAdvances1(12) pp. 731​-746​.​ DOI: https://doi.org/10.1096/fba.2019-00013 
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  • 2019 Journal Article | 
    ​ ​Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology​
    de Boer, R. A.; De Keulenaer, G.; Bauersachs, J.; Brutsaert, D.; Cleland, J. G.; Diez, J. & Du, X. et al.​ (2019) 
    European Journal of Heart Failure21(3) pp. 272​-285​.​ DOI: https://doi.org/10.1002/ejhf.1406 
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  • 2019 Journal Article | Research Paper | 
    ​ ​KLF15-Wnt–Dependent Cardiac Reprogramming Up-Regulates SHISA3 in the Mammalian Heart​
    Noack, C. ; Iyer, L. M. ; Liaw, N. Y. ; Schoger, E.; Khadjeh, S. ; Wagner, E.   & Woelfer, M. et al.​ (2019) 
    Journal of the American College of Cardiology74(14) pp. 1804​-1819​.​ DOI: https://doi.org/10.1016/j.jacc.2019.07.076 
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  • 2019 Journal Article | Research Paper | 
    ​ ​Inhibition of Rho-associated kinases suppresses cardiac myofibroblast function in engineered connective and heart muscle tissues​
    Santos, G. L. ; Hartmann, S.; Zimmermann, W.-H. ; Ridley, A. & Lutz, S. ​ (2019) 
    Journal of Molecular and Cellular Cardiology134 pp. 13​-28​.​ DOI: https://doi.org/10.1016/j.yjmcc.2019.06.015 
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  • 2019 Journal Article | 
    ​ ​Studying Brugada Syndrome With an SCN1B Variants in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes​
    El-Battrawy, I.; Müller, J.; Zhao, Z.; Cyganek, L. ; Zhong, R.; Zhang, F. & Kleinsorge, M. et al.​ (2019) 
    Frontiers in Cell and Developmental Biology7.​ DOI: https://doi.org/10.3389/fcell.2019.00261 
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  • 2019 Journal Article | Research Paper | 
    ​ ​Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish​
    Burczyk, M. S.; Burkhalter, M. D.; Tena, T. C.; Grisanti, L. A.; Kauk, M.; Matysik, S. & Donow, C. et al.​ (2019) 
    JCI Insight4(20).​ DOI: https://doi.org/10.1172/jci.insight.121971 
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  • 2019 Journal Article | Research Paper
    ​ ​Drug Testing in Human‐Induced Pluripotent Stem Cell–Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1​
    Zhao, Z.; Li, X.; El‐Battrawy, I.; Lan, H.; Zhong, R.; Xu, Q. & Huang, M. et al.​ (2019) 
    Clinical Pharmacology & Therapeutics106(3) pp. 642​-651​.​ DOI: https://doi.org/10.1002/cpt.1449 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Research Paper
    ​ ​Cardiac macrotissues-on-a-plate models for phenotypic drug screens​
    Meyer, T. ; Tiburcy, M.   & Zimmermann, W.-H. ​ (2019) 
    Advanced Drug Delivery Reviews140 pp. 93​-100​.​ DOI: https://doi.org/10.1016/j.addr.2019.03.002 
    Details  DOI  PMID  PMC 
  • 2019 Journal Article | Research Paper | 
    ​ ​Optogenetic Monitoring of the Glutathione Redox State in Engineered Human Myocardium​
    Trautsch, I.; Heta, E.; Soong, P. L. ; Levent, E. ; Nikolaev, V. O. ; Bogeski, I.   & Katschinski, D. M.  et al.​ (2019) 
    Frontiers in Physiology10.​ DOI: https://doi.org/10.3389/fphys.2019.00272 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Modeling heart failure for therapeutic screens in engineered human myocardium​
    Tiburcy, M. ; Meyer, T. ; Long, C.; Olson, E. N. & Zimmermann, W.-H. ​ (2018) 
    Journal of Pharmacological and Toxicological Methods93 pp. 170​.​ DOI: https://doi.org/10.1016/j.vascn.2018.01.549 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Highlighting the Field of Cardiovascular Regenerative Medicine​
    Zimmermann, W.-H. ; Yla-Herttuala, S. & Hajjar, R. J.​ (2018) 
    Molecular Therapy26(7) pp. 1595​.​ DOI: https://doi.org/10.1016/j.ymthe.2018.06.009 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Myocardial tissue engineering strategies for heart repair: current state of the art​
    Fujita, B.   & Zimmermann, W.-H. ​ (2018) 
    Interactive Cardiovascular and Thoracic Surgery,.​ DOI: https://doi.org/10.1093/icvts/ivy208 
    Details  DOI 
  • 2018 Journal Article
    ​ ​IGFBP5 controls human cardiac cell commitment and interferes with cardiomyocyte differentiation​
    Woelfer, M.; Iyer, L.; Chebbock, E.; Khadjeh, S.; Raad, F.; Zimmermann, W.-H.   & Zelarayan, L.​ (2018) 
    Journal of Molecular and Cellular Cardiology120 pp. 47​.​ DOI: https://doi.org/10.1016/j.yjmcc.2018.05.139 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Cardiomyocytes remuscularize the heart​
    Zimmermann, W.-H. ​ (2018) 
    Nature Biotechnology36(7) pp. 592​-593​.​ DOI: https://doi.org/10.1038/nbt.4186 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction​
    Zhao, X.; Chen, H.; Xiao, D.; Yang, H.; Itzhaki, I.; Qin, X. & Chour, T. et al.​ (2018) 
    Stem Cell Reports10(2) pp. 422​-435​.​ DOI: https://doi.org/10.1016/j.stemcr.2018.01.002 
    Details  DOI 
  • 2018 Journal Article
    ​ ​A scale model of the human ventricle​
    Zimmermann, W.-H. ​ (2018) 
    Nature Biomedical Engineering2(12) pp. 888​-889​.​ DOI: https://doi.org/10.1038/s41551-018-0332-9 
    Details  DOI 
  • 2018 Journal Article | Research Paper
    ​ ​Sex-specific regulation of collagen I and III expression by 17β-Estradiol in cardiac fibroblasts: role of estrogen receptors​
    Dworatzek, E.; Mahmoodzadeh, S.; Schriever, C.; Kusumoto, K.; Kramer, L.; Santos, G.   & Fliegner, D. et al.​ (2018) 
    Cardiovascular Research115(2) pp. 315​-327​.​ DOI: https://doi.org/10.1093/cvr/cvy185 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Engineered Nanoparticles Prevent Dilation of Abdominal Aortic Aneurysms​
    Zimmermann, W.-H. ​ (2018) 
    Journal of the American College of Cardiology72(21) pp. 2606​-2608​.​ DOI: https://doi.org/10.1016/j.jacc.2018.08.2187 
    Details  DOI 
  • 2018 Journal Article | Research Paper
    ​ ​Inotropy and chronotropy screens in engineered human myocardium by video-optical analysis in a 48 well format​
    Meyer, T. ; Tiburcy, M. ; Küpper, N.; Blendowske, R. & Zimmermann, W.-H. ​ (2018) 
    Journal of Pharmacological and Toxicological Methods93 pp. 127​-128​.​ DOI: https://doi.org/10.1016/j.vascn.2018.01.429 
    Details  DOI 
  • 2018 Journal Article | Research Paper | 
    ​ ​Deep phenotyping of human induced pluripotent stem cell–derived atrial and ventricular cardiomyocytes​
    Cyganek, L. ; Tiburcy, M. ; Sekeres, K.; Gerstenberg, K.; Bohnenberger, H. ; Lenz, C.   & Henze, S.  et al.​ (2018) 
    JCI Insight3(12) art. e99941​.​ DOI: https://doi.org/10.1172/jci.insight.99941 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy​
    El-Battrawy, I.; Zhao, Z.; Lan, H.; Li, X.; Yücel, G.; Lang, S. & Sattler, K. et al.​ (2018) 
    Circulation: Genomic and Precision Medicine11(3).​ DOI: https://doi.org/10.1161/CIRCGEN.117.001893 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Electrical dysfunctions in human-induced pluripotent stem cell-derived cardiomyocytes from a patient with an arrhythmogenic right ventricular cardiomyopathy​
    El-Battrawy, I.; Zhao, Z.; Lan, H.; Cyganek, L. ; Tombers, C.; Li, X. & Buljubasic, F. et al.​ (2018) 
    Europace20(FI1) pp. f46​-f56​.​ DOI: https://doi.org/10.1093/europace/euy042 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Modeling Short QT Syndrome Using Human‐Induced Pluripotent Stem Cell–Derived Cardiomyocytes​
    El‐Battrawy, I.; Lan, H.; Cyganek, L. ; Zhao, Z.; Li, X.; Buljubasic, F. & Lang, S. et al.​ (2018) 
    Journal of the American Heart Association7(7).​ DOI: https://doi.org/10.1161/JAHA.117.007394 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing​
    Long, C.; Li, H.; Tiburcy, M. ; Rodriguez-Caycedo, C.; Kyrychenko, V.; Zhou, H. & Zhang, Y. et al.​ (2018) 
    Science Advances4(1) art. eaap9004​.​ DOI: https://doi.org/10.1126/sciadv.aap9004 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper | 
    ​ ​Ion Channel Expression and Characterization in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes​
    Zhao, Z.; Lan, H.; El-Battrawy, I.; Li, X.; Buljubasic, F.; Sattler, K. & Yücel, G. et al.​ (2018) 
    Stem Cells International2018 pp. 1​-14​.​ DOI: https://doi.org/10.1155/2018/6067096 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Estradiol protection against toxic effects of catecholamine on electrical properties in human-induced pluripotent stem cell derived cardiomyocytes​
    El-Battrawy, I.; Zhao, Z.; Lan, H.; Schünemann, J.-D.; Sattler, K.; Buljubasic, F. & Patocskai, B. et al.​ (2018) 
    International Journal of Cardiology254 pp. 195​-202​.​ DOI: https://doi.org/10.1016/j.ijcard.2017.11.007 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper
    ​ ​Treatments targeting inotropy​
    Maack, C.; Eschenhagen, T. ; Hamdani, N.; Heinzel, F. R.; Lyon, A. R.; Manstein, D. J. & Metzger, J. et al.​ (2018) 
    European Heart Journal, art. ehy600​.​ DOI: https://doi.org/10.1093/eurheartj/ehy600 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper | 
    ​ ​CD8+-T Cells With Specificity for a Model Antigen in Cardiomyocytes Can Become Activated After Transverse Aortic Constriction but Do Not Accelerate Progression to Heart Failure​
    Gröschel, C.; Sasse, A.; Monecke, S.; Röhrborn, C.; Elsner, L.; Didié, M. & Reupke, V. et al.​ (2018) 
    Frontiers in Immunology9 art. 2665​.​ DOI: https://doi.org/10.3389/fimmu.2018.02665 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | Research Paper
    ​ ​Heat shock protein 47 knockout in fibroblasts causes contractile dysfunction in engineered human myocardium​
    Sur, S.; Noack, C.; Christalla, P.; Tiburcy, M. ; Nagata, K.; Mayr, M. & Zimmermann, W.-H. ​ (2017) 
    European Heart Journal38(suppl_1) art. 5044​.​ DOI: https://doi.org/10.1093/eurheartj/ehx493.5044 
    Details  DOI 
  • 2017 Journal Article | Research Paper
    ​ ​Inducible paracrine release of IGF-1 improves heart muscle thickness and function​
    Soong, P. L. ; Sur, S.; Fujita, B. ; Grishina, E.; Kuzyakova, M.; Tiburcy, M.   & Zimmermann, W. H. ​ (2017) 
    European Heart Journal38(suppl_1) art. P2545​.​ DOI: https://doi.org/10.1093/eurheartj/ehx502.P2545 
    Details  DOI 
  • 2017 Journal Article | Overview
    ​ ​Translating Myocardial Remuscularization​
    Zimmermann, W.-H. ​ (2017) 
    Circulation Research120(2) pp. 278​-281​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.116.310194 
    Details  DOI 
  • 2017 Journal Article | Research Paper
    ​ ​Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair​
    Tiburcy, M. ; Hudson, J. E.; Balfanz, P.; Schlick, S.; Meyer, T. ; Chang Liao, M.-L. & Levent, E. et al.​ (2017) 
    Circulation135(19) pp. 1832​-1847​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.116.024145 
    Details  DOI 
  • 2017 Journal Article | Overview
    ​ ​Myocardial Tissue Engineering for Regenerative Applications​
    Fujita, B.   & Zimmermann, W.-H. ​ (2017) 
    Current Cardiology Reports19(9) art. 78​.​ DOI: https://doi.org/10.1007/s11886-017-0892-4 
    Details  DOI 
  • 2017 Journal Article | Overview
    ​ ​Engineered Heart Repair​
    Fujita, B.   & Zimmermann, W.-H. ​ (2017) 
    Clinical Pharmacology & Therapeutics102(2) pp. 197​-199​.​ DOI: https://doi.org/10.1002/cpt.724 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery​
    Ewart, L.; Dehne, E.-M.; Fabre, K.; Gibbs, S.; Hickman, J.; Hornberg, E. & Ingelman-Sundberg, M. et al.​ (2017) 
    Annual Review of Pharmacology and Toxicology58(1) pp. 65​-82​.​ DOI: https://doi.org/10.1146/annurev-pharmtox-010617-052722 
    Details  DOI 
  • 2017 Journal Article | Overview
    ​ ​Remuscularization of the failing heart​
    Zimmermann, W.-H. ​ (2017) 
    The Journal of Physiology595(12) pp. 3685​-3690​.​ DOI: https://doi.org/10.1113/jp273098 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Inhibition of exosome release by ketotifen enhances sensitivity of cancer cells to doxorubicin​
    Khan, F. M.; Saleh, E.; Alawadhi, H.; Harati, R.; Zimmermann, W.-H.   & El-Awady, R.​ (2017) 
    Cancer Biology & Therapy19(1) pp. 25​-33​.​ DOI: https://doi.org/10.1080/15384047.2017.1394544 
    Details  DOI 
  • 2017 Journal Article | 
    ​ ​Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes​
    Yücel, G.; Zhao, Z.; El-Battrawy, I.; Lan, H.; Lang, S.; Li, X. & Buljubasic, F. et al.​ (2017) 
    Scientific Reports7(1) art. 2935​.​ DOI: https://doi.org/10.1038/s41598-017-03147-4 
    Details  DOI 
  • 2017 Journal Article | Research Paper | 
    ​ ​Immunological Properties of Murine Parthenogenetic Stem Cell-Derived Cardiomyocytes and Engineered Heart Muscle​
    Didié, M. ; Galla, S. ; Muppala, V. ; Dressel, R.   & Zimmermann, W.-H. ​ (2017) 
    Frontiers in Immunology8 art. 955​.​ DOI: https://doi.org/10.3389/fimmu.2017.00955 
    Details  DOI 
  • 2017 Journal Article | Overview | 
    ​ ​Cardiac optogenetics: using light to monitor cardiac physiology​
    Koopman, C. D.; Zimmermann, W. H. ; Knöpfel, T. & de Boer, T. P.​ (2017) 
    Basic Research in Cardiology112(5) art. 56​.​ DOI: https://doi.org/10.1007/s00395-017-0645-y 
    Details  DOI 
  • 2017 Journal Article | Research Paper | 
    ​ ​T helper cells with specificity for an antigen in cardiomyocytes promote pressure overload-induced progression from hypertrophy to heart failure​
    Gröschel, C. ; Sasse, A. ; Röhrborn, C. ; Monecke, S. ; Didié, M. ; Elsner, L.   & Kruse, V.  et al.​ (2017) 
    Scientific Reports7(1) art. 15998​.​ DOI: https://doi.org/10.1038/s41598-017-16147-1 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | Research Paper
    ​ ​Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling​
    Abilez, O. J.; Tzatzalos, E.; Yang, H.; Zhao, M.-T.; Jung, G.; Zöllner, A. M. & Tiburcy, M.  et al.​ (2017) 
    Stem Cells36(2) pp. 265​-277​.​ DOI: https://doi.org/10.1002/stem.2732 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | Research Paper | 
    ​ ​Immunological Properties of Murine Parthenogenetic Stem Cells and Their Differentiation Products​
    Johannsen, H. ; Muppala, V. ; Gröschel, C. ; Monecke, S. ; Elsner, L. ; Didié, M.   & Zimmermann, W.-H.  et al.​ (2017) 
    Frontiers in Immunology8 art. 924​.​ DOI: https://doi.org/10.3389/fimmu.2017.00924 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | Research Paper | 
    ​ ​Generation of a KLF15 homozygous knockout human embryonic stem cell line using paired CRISPR/Cas9n, and human cardiomyocytes derivation​
    Noack, C. ; Haupt, L. P. ; Zimmermann, W.-H. ; Streckfuss-Bömeke, K.   & Zelarayán, L. C. ​ (2017) 
    Stem Cell Research23 pp. 127​-131​.​ DOI: https://doi.org/10.1016/j.scr.2017.07.007 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | Research Paper | 
    ​ ​Catecholamine-Dependent β-Adrenergic Signaling in a Pluripotent Stem Cell Model of Takotsubo Cardiomyopathy​
    Borchert, T. ; Hübscher, D. ; Guessoum, C. I. ; Lam, T. Lam, Tuan-Dinh D.; Ghadri, J. R.; Schellinger, I. N.   & Tiburcy, M.  et al.​ (2017) 
    Journal of the American College of Cardiology70(8) pp. 975​-991​.​ DOI: https://doi.org/10.1016/j.jacc.2017.06.061 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | Research Paper | 
    ​ ​Functional correction of dystrophin actin binding domain mutations by genome editing​
    Kyrychenko, V.; Kyrychenko, S.; Tiburcy, M. ; Shelton, J. M.; Long, C.; Schneider, J. W. & Zimmermann, W.-H.  et al.​ (2017) 
    JCI Insight2(18) art. e95918​.​ DOI: https://doi.org/10.1172/jci.insight.95918 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | Research Paper | 
    ​ ​Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes​
    Streckfuss-Bömeke, K. ; Tiburcy, M. ; Fomin, A.; Luo, X.; Li, W.; Fischer, C. & Özcelik, C. et al.​ (2017) 
    Journal of Molecular and Cellular Cardiology113 pp. 9​-21​.​ DOI: https://doi.org/10.1016/j.yjmcc.2017.09.008 
    Details  DOI  PMID  PMC 
  • 2016 Journal Article
    ​ ​Inotropy and chronotropy screens in engineered human myocardium​
    Meyer, T. ; Tiburcy, M.   & Zimmermann, W.-H. ​ (2016) 
    Journal of Pharmacological and Toxicological Methods81 pp. 373​.​ DOI: https://doi.org/10.1016/j.vascn.2016.02.125 
    Details  DOI 
  • 2016 Journal Article | 
    ​ ​Hyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes​
    El-Battrawy, I.; Lang, S.; Zhao, Z.; Akin, I.; Yücel, G.; Meister, S. & Patocskai, B. et al.​ (2016) 
    PLOS ONE11(11) art. e0166143​.​ DOI: https://doi.org/10.1371/journal.pone.0166143 
    Details  DOI 
  • 2016 Journal Article | 
    ​ ​Computational Detection of Stage-Specific Transcription Factor Clusters during Heart Development​
    Zeidler, S. ; Meckbach, C. ; Tacke, R.; Raad, F. S. ; Roa, A.; Uchida, S. & Zimmermann, W.-H.  et al.​ (2016) 
    Frontiers in Genetics7 art. 33​.​ DOI: https://doi.org/10.3389/fgene.2016.00033 
    Details  DOI 
  • 2016 Journal Article | 
    ​ ​All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class​
    Castillo-Gómez, E.; Oliveira, B. ; Tapken, D.; Bertrand, S.; Klein-Schmidt, C.; Pan, H. & Zafeiriou, M.-P.  et al.​ (2016) 
    Molecular Psychiatry22(12) pp. 1776​-1784​.​ DOI: https://doi.org/10.1038/mp.2016.125 
    Details  DOI 
  • 2016 Journal Article | Research Paper
    ​ ​Distilling complexity to advance cardiac tissue engineering​
    Ogle, B. M.; Bursac, N.; Domian, I.; Huang, N. F.; Menasche, P.; Murry, C. E. & Pruitt, B. et al.​ (2016) 
    Science Translational Medicine8(342) art. 342ps13​.​ DOI: https://doi.org/10.1126/scitranslmed.aad2304 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue)
    ​ ​Strip and Dress the Human Heart​
    Zimmermann, W.-H. ​ (2016) 
    Circulation Research118(1) pp. 12​-13​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.115.307938 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Overview
    ​ ​Mechanical stimulation in the engineering of heart muscle​
    Liaw, N. Y.   & Zimmermann, W.-H. ​ (2016) 
    Advanced Drug Delivery Reviews96 pp. 156​-160​.​ DOI: https://doi.org/10.1016/j.addr.2015.09.001 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Erratum | 
    ​ ​Erratum to: Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by Injury​
    Ott, C.; Martens, H.; Hassouna, I.; Oliveira, B.; Erck, C.; Zafeiriou, M.-P. & Peteri, U.-K. et al.​ (2015) 
    Molecular Medicine21(1) pp. 816​-816​.​ DOI: https://doi.org/10.2119/molmed.2015.00192.erratum 
    Details  DOI 
  • 2015 Journal Article | Research Paper | 
    ​ ​Widespread expression of erythropoietin receptor in brain and its induction by injury​
    Ott, C. ; Martens, H.; Hassouna, I. ; Oliveira, B. ; Erck, C.; Zafiriou, M. P.   & Peteri, U.-K.  et al.​ (2015) 
    Molecular Medicine21(1) pp. 803​-815​.​ DOI: https://doi.org/10.2119/molmed.2015.00192 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | Research Paper
    ​ ​Sensing Cardiac Electrical Activity With a Cardiac Myocyte-Targeted Optogenetic Voltage Indicator​
    Chang Liao, M.-L.; Boer, T. P. de; Mutoh, H.; Raad, N.; Richter, C. ; Wagner, E.   & Downie, B. R. et al.​ (2015) 
    Circulation Research117(5) pp. 401​-412​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.117.306143 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​RhoA Ambivalently Controls Prominent Myofibroblast Characteritics by Involving Distinct Signaling Routes​
    Jatho, A. ; Hartmann, S.; Kittana, N.; Muegge, F.; Wuertz, C. M. ; Tiburcy, M.   & Zimmermann, W.-H.  et al.​ (2015) 
    PLoS ONE10(10) art. e0137519​.​ DOI: https://doi.org/10.1371/journal.pone.0137519 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper
    ​ ​Physiologic force-frequency response in engineered heart muscle by electromechanical stimulation​
    Godier-Furnemont, A. F. G.; Tiburcy, M. ; Wagner, E. ; Dewenter, M. ; Laemmle, S.; El-Armouche, A.   & Lehnart, S. E.  et al.​ (2015) 
    Biomaterials60 pp. 82​-91​.​ DOI: https://doi.org/10.1016/j.biomaterials.2015.03.055 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper
    ​ ​S100A1 DNA-based Inotropic Therapy Protects Against Proarrhythmogenic Ryanodine Receptor 2 Dysfunction​
    Ritterhoff, J.; Voelkers, M.; Seitz, A.; Spaich, K.; Gao, E.; Peppel, K. & Pleger, S. T. et al.​ (2015) 
    Molecular Therapy23(8) pp. 1320​-1330​.​ DOI: https://doi.org/10.1038/mt.2015.93 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function​
    Sharma, P.; Abbasi, C.; Lazic, S.; Teng, A. C. T.; Wang, D.; Dubois, N. & Ignatchenko, V. et al.​ (2015) 
    Nature Communications6 art. 8391​.​ DOI: https://doi.org/10.1038/ncomms9391 
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  • 2015 Journal Article | Letter Note
    ​ ​New Biologics for the Modulation of Post-Infarct Remodeling Matricryptins​
    Zimmermann, W.-H. ​ (2015) 
    Journal of the American College of Cardiology66(12) pp. 1375​-1377​.​ DOI: https://doi.org/10.1016/j.jacc.2015.07.039 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper
    ​ ​Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model​
    Riegler, J.; Tiburcy, M. ; Ebert, A. ; Tzatzalos, E.; Raaz, U. ; Abilez, O. J. & Shen, Q. et al.​ (2015) 
    Circulation Research117(8) pp. 720​-730​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.115.306985 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper
    ​ ​p63RhoGEF regulates auto- and paracrine signaling in cardiac fibroblasts​
    Ongherth, A.; Pasch, S.; Wuertz, C. M. ; Nowak, K.; Kittana, N.; Weis, C. A. & Jatho, A.  et al.​ (2015) 
    Journal of Molecular and Cellular Cardiology88 pp. 39​-54​.​ DOI: https://doi.org/10.1016/j.yjmcc.2015.09.009 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Cardiac Engraftment of Genetically-Selected Parthenogenetic Stem Cell-Derived Cardiomyocytes​
    Yang, T.; Rubart, M.; Soonpaa, M. H.; Didie, M. ; Christalla, P.; Zimmermann, W.-H.   & Field, L. J.​ (2015) 
    PLoS ONE10(6) art. e0131511​.​ DOI: https://doi.org/10.1371/journal.pone.0131511 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper
    ​ ​Individualized stem cell therapy​
    Zimmermann, W.-H. ​ (2014) 
    Herz39(2) pp. 201​-205​.​ DOI: https://doi.org/10.1007/s00059-014-4073-6 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | Research Paper | 
    ​ ​Lights on for HIF-1 alpha: Genetically Enhanced Mouse Cardiomyocytes for Heart Tissue Imaging​
    Hesse, A. R.; Levent, E. ; Zieseniss, A. ; Tiburcy, M. ; Zimmermann, W.-H.   & Katschinski, D. M. ​ (2014) 
    Cellular Physiology and Biochemistry34(2) pp. 455​-462​.​ DOI: https://doi.org/10.1159/000363014 
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  • 2014 Journal Article | Research Paper
    ​ ​PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways​
    Vettel, C. ; Lämmle, S.; Ewens, S.; Cervirgen, C.; Emmons, J.; Ongherth, A. & Dewenter, M.  et al.​ (2014) 
    American Journal of Physiology - Heart and Circulatory Physiology306(8) pp. H1246​-H1252​.​ DOI: https://doi.org/10.1152/ajpheart.00852.2013 
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  • 2014 Journal Article | Research Paper | 
    ​ ​Erythropoietin Responsive Cardiomyogenic Cells Contribute to Heart Repair Post Myocardial Infarction​
    Zafiriou, M. P. ; Noack, C. ; Unsoeld, B. W.; Didie, M. ; Pavlova, E.; Fischer, H. J.   & Reichardt, H. M.  et al.​ (2014) 
    STEM CELLS32(9) pp. 2480​-2491​.​ DOI: https://doi.org/10.1002/stem.1741 
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  • 2014 Journal Article | Research Paper | 
    ​ ​miR-133a Enhances the Protective Capacity of Cardiac Progenitors Cells after Myocardial Infarction​
    Izarra, A.; Moscoso, I.; Levent, E. ; Canon, S.; Cerrada, I.; Diez-Juan, A. & Blanca, V. et al.​ (2014) 
    Stem Cell Reports3(6) pp. 1029​-1042​.​ DOI: https://doi.org/10.1016/j.stemcr.2014.10.010 
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  • 2014 Journal Article | Overview
    ​ ​Modeling myocardial growth and hypertrophy in engineered heart muscle​
    Tiburcy, M.   & Zimmermann, W.-H. ​ (2014) 
    Trends in Cardiovascular Medicine24(1) pp. 7​-13​.​ DOI: https://doi.org/10.1016/j.tcm.2013.05.003 
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  • 2013 Journal Article
    ​ ​Myocardial Tissue Engineering and Heart Muscle Repair​
    Chandapillai Karikkineth, B. & Zimmermann, W.-H. ​ (2013) 
    Current Pharmaceutical Biotechnology14(1) pp. 4​-11​.​ DOI: https://doi.org/10.2174/138920113804805322 
    Details  DOI 
  • 2013 Journal Article | Overview | 
    ​ ​Biomechanical regulation of in vitro cardiogenesis for tissue-engineered heart repair​
    Zimmermann, W.-H. ​ (2013) 
    Stem Cell Research & Therapy4 art. 137​.​ DOI: https://doi.org/10.1186/scrt348 
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  • 2013 Journal Article | Research Paper | 
    ​ ​Enhanced Ca2+ influx through cardiac L-type Ca2+ channels maintains the systolic Ca2+ transient in early cardiac atrophy induced by mechanical unloading​
    Schwoerer, A. P.; Neef, S.; Broichhausen, I.; Jacubeit, J.; Tiburcy, M. ; Wagner, M. & Biermann, D. et al.​ (2013) 
    Pflügers Archiv - European Journal of Physiology465(12) pp. 1763​-1773​.​ DOI: https://doi.org/10.1007/s00424-013-1316-y 
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  • 2013 Journal Article | Research Paper | 
    ​ ​The Four and a Half LIM-Domain 2 Controls Early Cardiac Cell Commitment and Expansion Via Regulating β-Catenin-Dependent Transcription​
    Renger, A.; Zafiriou, M.-P. ; Noack, C. ; Pavlova, E.; Becker, A. ; Sharkova, K. & Bergmann, M. W. et al.​ (2013) 
    Stem Cells31(5) pp. 928​-940​.​ DOI: https://doi.org/10.1002/stem.1332 
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  • 2013 Journal Article | Research Paper
    ​ ​Parthenogenetic stem cells for tissue-engineered heart repair​
    Didie, M. ; Christalla, P.; Rubart, M.; Muppala, V. ; Doeker, S.; Unsoeld, B. W. & El-Armouche, A.  et al.​ (2013) 
    Journal of Clinical Investigation123(3) pp. 1285​-1298​.​ DOI: https://doi.org/10.1172/JCI66854 
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  • 2013 Journal Article | Research Paper
    ​ ​Preservation of left ventricular function and morphology in volume-loaded versus volume-unloaded heterotopic heart transplants​
    Didie, M. ; Biermann, D.; Buchert, R.; Hess, A.; Wittkoepper, K.; Christalla, P. & Doeker, S. et al.​ (2013) 
    American Journal of Physiology - Heart and Circulatory Physiology305(4) pp. H533​-H541​.​ DOI: https://doi.org/10.1152/ajpheart.00218.2013 
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  • 2013 Journal Article | Research Paper
    ​ ​Phosphodiesterase-2 Is Up-Regulated in Human Failing Hearts and Blunts β-Adrenergic Responses in Cardiomyocytes​
    Mehel, H.; Emons, J.; Vettel, C. ; Wittköpper, K.; Seppelt, D.; Dewenter, M.   & Lutz, S.  et al.​ (2013) 
    Journal of the American College of Cardiology62(17) pp. 1596​-1606​.​ DOI: https://doi.org/10.1016/j.jacc.2013.05.057 
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  • 2013 Journal Article | Research Paper
    ​ ​Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts​
    Streckfuss-Boemeke, K. ; Wolf, F.; Azizian, A. ; Stauske, M.; Tiburcy, M. ; Wagner, S.   & Huebscher, D.  et al.​ (2013) 
    European heart journal34(33) pp. 2618​-2629​.​ DOI: https://doi.org/10.1093/eurheartj/ehs203 
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  • 2013 Journal Article | Research Paper
    ​ ​Extracellular Matrix Secretion by Cardiac Fibroblasts: ​Role of MicroRNA-29b and MicroRNA-30c​
    Abonnenc, M.; Nabeebaccus, A. A.; Mayr, U.; Barallobre-Barreiro, J.; Dong, X.; Cuello, F. & Sur, S. et al.​ (2013) 
    Circulation Research113(10) pp. 1138​-1147​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.113.302400 
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  • 2013 Journal Article | Overview
    ​ ​Patching the Heart Cardiac Repair From Within and Outside​
    Ye, L.; Zimmermann, W.-H. ; Garry, D. J. & Zhang, J.​ (2013) 
    Circulation Research113(7) pp. 922​-932​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.113.300216 
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  • 2012 Journal Article
    ​ ​Cardiac Differentiation of Human Embryonic Stem Cells and their Assembly into Engineered Heart Muscle​
    Soong, P. L. ; Tiburcy, M.   & Zimmermann, W.-H. ​ (2012) 
    Current Protocols in Cell Biology,.​ DOI: https://doi.org/10.1002/0471143030.cb2308s55 
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  • 2012 Journal Article | Research Paper | 
    ​ ​The Cardiogenic Niche as a Fundamental Building Block of Engineered Myocardium​
    Christalla, P.; Hudson, J. E.   & Zimmermann, W.-H. ​ (2012) 
    Cells Tissues Organs195(1-2) pp. 82​-93​.​ DOI: https://doi.org/10.1159/000331407 
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  • 2012 Journal Article | Research Paper | 
    ​ ​Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data​
    Fredersdorf, S.; Thumann, C.; Zimmermann, W.-H. ; Vetter, R.; Graf, T.; Luchner, A. & Riegger, G. A. J. et al.​ (2012) 
    Cardiovascular Diabetology11 art. 57​.​ DOI: https://doi.org/10.1186/1475-2840-11-57 
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  • 2012 Journal Article | Research Paper | 
    ​ ​Krueppel-like factor 15 regulates Wnt/ss-catenin transcription and controls cardiac progenitor cell fate in the postnatal heart​
    Noack, C. ; Zafiriou, M.-P. ; Schaeffer, H.-J.; Renger, A.; Pavlova, E.; Dietz, R. & Zimmermann, W.-H.  et al.​ (2012) 
    EMBO Molecular Medicine4(9) pp. 992​-1007​.​ DOI: https://doi.org/10.1002/emmm.201101043 
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  • 2012 Journal Article | Research Paper | 
    ​ ​Impact of AT2 Receptor Deficiency on Postnatal Cardiovascular Development​
    Biermann, D.; Heilmann, A.; Didie, M. ; Schlossarek, S.; Wahab, A.; Grimm, M.   & Roemer, M. et al.​ (2012) 
    PLoS ONE7(10) art. e47916​.​ DOI: https://doi.org/10.1371/journal.pone.0047916 
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  • 2012 Journal Article | Research Paper
    ​ ​Targeted disruption of Hspa4 gene leads to cardiac hypertrophy and fibrosis​
    Mohamed, B. A. ; Barakat, A. Z.; Zimmermann, W.-H. ; Bittner, R. E.; Muehlfeld, C.; Huenlich, M.   & Engel, W. et al.​ (2012) 
    Journal of Molecular and Cellular Cardiology53(4) pp. 459​-468​.​ DOI: https://doi.org/10.1016/j.yjmcc.2012.07.014 
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  • 2011 Journal Article
    ​ ​Cardiac tissue engineering: a clinical perspective​
    Zimmermann, W.-H. ; Tiburcy, M.   & Eschenhagen, T. ​ (2011) 
    Future Cardiology3(4) pp. 435​-445​.​ DOI: https://doi.org/10.2217/14796678.3.4.435 
    Details  DOI 
  • 2011 Journal Article | Research Paper
    ​ ​Engineering bioartificial tracheal tissue using hybrid fibroblast-mesenchymal stem cell cultures in collagen hydrogels​
    Naito, H.; Tojo, T.; Kimura, M.; Dohi, Y.; Zimmermann, W.-H. ; Eschenhagen, T.   & Taniguchi, S.​ (2011) 
    Interactive CardioVascular and Thoracic Surgery12(2) pp. 156​-161​.​ DOI: https://doi.org/10.1510/icvts.2010.253559 
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  • 2011 Journal Article | Research Paper | 
    ​ ​Extracellular Signal-Regulated Kinases 1 and 2 Regulate the Balance Between Eccentric and Concentric Cardiac Growth​
    Kehat, I.; Davis, J.; Tiburcy, M. ; Accornero, F.; Saba-El-Leil, M. K.; Maillet, M. & York, A. J. et al.​ (2011) 
    Circulation Research108(2) pp. 176​-U57​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.110.231514 
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  • 2011 Journal Article | Research Paper
    ​ ​Disruption of Platelet-Derived Growth Factor-Dependent Phosphatidylinositol 3-Kinase and Phospholipase C gamma 1 Activity Abolishes Vascular Smooth Muscle Cell Proliferation and Migration and Attenuates Neointima Formation In Vivo​
    Caglayan, E.; van Tol, M.-J.; Leppaenen, O.; Gerhardt, F.; Mustafov, L.; ten Freyhaus, H. & Kappert, K. et al.​ (2011) 
    Journal of the American College of Cardiology57(25) pp. 2527​-2538​.​ DOI: https://doi.org/10.1016/j.jacc.2011.02.037 
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  • 2011 Journal Article | Research Paper | 
    ​ ​Transforming Growth Factor beta(1) Oppositely Regulates the Hypertrophic and Contractile Response to beta-Adrenergic Stimulation in the Heart​
    Huntgeburth, M.; Tiemann, K.; Shahverdyan, R.; Schlueter, K.-D.; Schreckenberg, R.; Gross, M.-L. & Moedersheim, S. et al.​ (2011) 
    PLoS ONE6(11) art. e26628​.​ DOI: https://doi.org/10.1371/journal.pone.0026628 
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  • 2011 Journal Article | Research Paper | 
    ​ ​Diastolic dysfunction and arrhythmias caused by overexpression of CaMKII delta(C) can be reversed by inhibition of late Na+ current​
    Sossalla, S. ; Maurer, U.; Schotola, H.; Hartmann, N. H. ; Didie, M. ; Zimmermann, W.-H.   & Jacobshagen, C.  et al.​ (2011) 
    Basic Research in Cardiology106(2) pp. 263​-272​.​ DOI: https://doi.org/10.1007/s00395-010-0136-x 
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  • 2011 Journal Article | Research Paper
    ​ ​Telethonin Deficiency Is Associated With Maladaptation to Biomechanical Stress in the Mammalian Heart​
    Knöll, R.; Linke, W. A. ; Zou, P.; Miocic, S.; Kostin, S.; Buyandelger, B. & Ku, C.-H. et al.​ (2011) 
    Circulation Research109(7) pp. 758​-U153​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.111.245787 
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  • 2011 Journal Article | Research Paper | 
    ​ ​Terminal Differentiation, Advanced Organotypic Maturation, and Modeling of Hypertrophic Growth in Engineered Heart Tissue​
    Tiburcy, M. ; Didie, M. ; Boy, O.; Christalla, P.; Doeker, S.; Naito, H. & Karikkineth, B. C. et al.​ (2011) 
    Circulation Research109(10) pp. 1105​-U46​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.111.251843 
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  • 2011 Journal Article | Research Paper
    ​ ​Human Engineered Heart Tissue as a Versatile Tool in Basic Research and Preclinical Toxicology​
    Schaaf, S.; Shibamiya, A.; Mewe, M.; Eder, A.; Stoehr, A.; Hirt, M. N. & Rau, T. et al.​ (2011) 
    PLoS ONE6(10) art. e26397​.​ DOI: https://doi.org/10.1371/journal.pone.0026397 
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  • 2011 Journal Article | Research Paper
    ​ ​The Effect of Mesenchymal Stem Cell Osteoblastic Differentiation on the Mechanical Properties of Engineered Bone-Like Tissue​
    Naito, H.; Dohi, Y.; Zimmermann, W.-H. ; Tojo, T.; Takasawa, S.; Eschenhagen, T.   & Taniguchi, S.​ (2011) 
    Tissue Engineering Part A17(17-18) pp. 2321​-2329​.​ DOI: https://doi.org/10.1089/ten.tea.2011.0099 
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  • 2011 Journal Article | Letter Note
    ​ ​Tuning Wnt-signaling to enhance cardiomyogenesis in human embryonic and induced pluripotent stem cells​
    Hudson, J. E.   & Zimmermann, W.-H. ​ (2011) 
    Journal of Molecular and Cellular Cardiology51(3) pp. 277​-279​.​ DOI: https://doi.org/10.1016/j.yjmcc.2011.06.011 
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  • 2010 Journal Article | Research Paper | 
    ​ ​Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation​
    Rudolph, V.; Andrié, R. P.; Rudolph, T. K.; Friedrichs, K.; Klinke, A.; Hirsch-Hoffmann, B. & Schwoerer, A. P. et al.​ (2010) 
    Nature Medicine16(4) pp. 470​-474​.​ DOI: https://doi.org/10.1038/nm.2124 
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  • 2010 Journal Article | Research Paper
    ​ ​PDGF-BB protects cardiomyocytes from apoptosis and improves contractile function of engineered heart tissue​
    van Tol, M.-J.; Karikkineth, B. C.; Naito, H.; Tiburcy, M. ; Didie, M. ; Nose, M. & Rosenkranz, S. et al.​ (2010) 
    Journal of Molecular and Cellular Cardiology48(6) pp. 1316​-1323​.​ DOI: https://doi.org/10.1016/j.yjmcc.2010.03.008 
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  • 2010 Journal Article | Research Paper
    ​ ​A Common MLP (Muscle LIM Protein) Variant Is Associated With Cardiomyopathy​
    Knöll, R.; Kostin, S.; Klede, S.; Savvatis, K.; Klinge, L. ; Stehle, I. & Gunkel, S. et al.​ (2010) 
    Circulation Research106(4) pp. 695​-704​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.109.206243 
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  • 2010 Journal Article | Research Paper | 
    ​ ​Common MicroRNA Signatures in Cardiac Hypertrophic and Atrophic Remodeling Induced by Changes in Hemodynamic Load​
    El-Armouche, A. ; Schwoerer, A. P.; Neuber, C.; Emmons, J.; Biermann, D.; Christalla, T. & Grundhoff, A. et al.​ (2010) 
    PLoS ONE5(12) art. e14263​.​ DOI: https://doi.org/10.1371/journal.pone.0014263 
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  • 2010 Journal Article | Research Paper
    ​ ​Skin Repair Using a Porcine Collagen I/III Membrane-Vascularization and Epithelization Properties​
    Wehrhan, F.; Nkenke, E.; Melnychenko, I.; Amann, K.; Schlegel, K. A.; Goerlach, C. & Zimmermann, W.-H.  et al.​ (2010) 
    Dermatologic Surgery36(6) pp. 919​-930​.​ DOI: https://doi.org/10.1111/j.1524-4725.2010.01569.x 
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  • 2009 Journal Article | Research Paper
    ​ ​405: Cytokine Enhancement with HGF or VEGF in the Infarct Border Zone Is Key to Attenuating the Negative Remodelling after Myocardial Infarction​
    Schrepfer, S.; Deuse, T.; Peter, C.; Stein, B.; Reichenspurner, H.; Zimmermann, W.-H.   & Eschenhagen, T. et al.​ (2009) 
    The Journal of Heart and Lung Transplantation28(2) pp. S206​.​ DOI: https://doi.org/10.1016/j.healun.2008.11.412 
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  • 2008 Journal Article | Research Paper
    ​ ​Postnatal Isl1+ progeny can be purified and cultivated from Isl1-Cre/R26-YFP mice​
    Friedrich, F.; Tiburcy, M. ; Zimmermann, W.-H. ; Carrier, L. & Eschenhagen, T.​ (2008) 
    Journal of Molecular and Cellular Cardiology44(4) pp. 810​-811​.​ DOI: https://doi.org/10.1016/j.yjmcc.2008.02.237 
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  • 2008 Journal Article | Research Paper
    ​ ​Heart tissue from embryonic stem cells​
    Zimmermann, W.-H. ​ (2008) 
    Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz51(9) pp. 1021​-1025​.​ DOI: https://doi.org/10.1007/s00103-008-0630-6 
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  • 2008 Journal Article | Research Paper
    ​ ​Thyroid hormone regulates developmental titin isoform transitions via the phosphatidylinositol-3-kinase/AKT pathway​
    Krueger, M. ; Sachse, C.; Zimmermann, W.-H. ; Eschenhagen, T. ; Klede, S. & Linke, W. A. ​ (2008) 
    Circulation Research102(4) pp. 439​-447​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.107.162719 
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  • 2008 Journal Article | Research Paper
    ​ ​Real-time myocardial contrast echocardiography for assessing perfusion and function in healthy and infarcted Wistar rats​
    Wasmeier, G. H.; Zimmermann, W.-H. ; Schineis, N.; Melnychenko, I.; Voigt, J.-U.; Eschenhagen, T.   & Flachskampf, F. A. et al.​ (2008) 
    Ultrasound in Medicine & Biology34(1) pp. 47​-55​.​ DOI: https://doi.org/10.1016/j.ultrasmedbio.2007.06.027 
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  • 2008 Journal Article | 
    ​ ​TISSUE ENGINEERING Polymers flex their muscles​
    Zimmermann, W.-H. ​ (2008) 
    Nature Materials7(12) pp. 932​-933​.​ DOI: https://doi.org/10.1038/nmat2328 
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  • 2008 Journal Article | Research Paper
    ​ ​Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy​
    El-Armouche, A. ; Wittkoepper, K.; Degenhardt, F.; Weinberger, F.; Didie, M. ; Melnychenko, I. & Grimm, M.  et al.​ (2008) 
    Cardiovascular Research80(3) pp. 396​-406​.​ DOI: https://doi.org/10.1093/cvr/cvn208 
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  • 2007 Journal Article
    ​ ​Embryonic Stem Cells for Cardiac Muscle Engineering​
    Zimmermann, W.-H.   & Eschenhagen, T. ​ (2007) 
    Trends in Cardiovascular Medicine17(4) pp. 134​-140​.​ DOI: https://doi.org/10.1016/j.tcm.2007.02.007 
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  • 2007 Journal Article | Research Paper
    ​ ​Adenovirus-delivered short hairpin RNA targeting contractile function in reconstituted heart PKC alpha improves tissue​
    El-Armouche, A. ; Singh, J.; Naito, H.; Wittkoepper, K.; Didie, M. ; Laatsch, A. & Zimmermann, W.-H.  et al.​ (2007) 
    Journal of Molecular and Cellular Cardiology43(3) pp. 371​-376​.​ DOI: https://doi.org/10.1016/j.yjmcc.2007.05.021 
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  • 2007 Journal Article | Research Paper
    ​ ​Reproducibility of transthoracic echocardiography in small animals using clinical equipment​
    Wasmeier, G. H.; Melnychenko, I.; Voigt, J.-U.; Zimmermann, W.-H. ; Eschenhagen, T. ; Schineis, N. & Reulbach, U. et al.​ (2007) 
    Coronary Artery Disease18(4) pp. 283​-291​.​ DOI: https://doi.org/10.1097/MCA.0b013e3280d5a7e3 
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  • 2006 Journal Article | Research Paper
    ​ ​Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts​
    Zimmermann, W.-H. ; Melnychenko, I.; Wasmeier, G. H.; Didie, M. ; Naito, H.; Nixdorff, U. & Hess, A. et al.​ (2006) 
    Nature Medicine12(4) pp. 452​-458​.​ DOI: https://doi.org/10.1038/nm1394 
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  • 2006 Journal Article | Letter Note
    ​ ​Electrical coupling of cardiac myocyte cell sheets to the heart​
    Eschenhagen, T. ; Zimmermann, W.-H.   & Kleber, A. G.​ (2006) 
    Circulation Research98(5) pp. 573​-575​.​ DOI: https://doi.org/10.1161/01.RES.0000215627.13049.5d 
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  • 2006 Journal Article | Research Paper
    ​ ​Alterations of the preproenkephalin system in cardiac hypertrophy and its role in atrioventricular conduction​
    Weil, J.; Zolk, O.; Griepentrog, J.; Wenzel, U.; Zimmermann, W.-H.   & Eschenhagen, T. ​ (2006) 
    Cardiovascular Research69(2) pp. 412​-422​.​ DOI: https://doi.org/10.1016/j.cardiores.2005.10.016 
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  • 2005 Journal Article | Research Paper
    ​ ​Endothelin-1 and isoprenaline co-stimulation causes contractile failure which is partially reversed by MEK inhibition​
    Münzel, F.; Muhlhauser, U.; Zimmermann, W.-H. ; Didie, M. ; Schneiderbanger, K.; Schubert, P. & Engmann, S. et al.​ (2005) 
    Cardiovascular Research68(3) pp. 464​-474​.​ DOI: https://doi.org/10.1016/j.cardiores.2005.06.020 
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  • 2005 Journal Article | Research Paper
    ​ ​Systematic evaluation of anti-apoptotic growth factor signaling in vascular smooth muscle cells - Only phosphatidylinositol 3 '-kinase is important​
    van Tol, M.-J.; Caglayan, E.; Zimmermann, W.-H. ; Baumer, A. T. & Rosenkranz, S.​ (2005) 
    Journal of biological chemistry280(14) pp. 14168​-14176​.​ DOI: https://doi.org/10.1074/jbc.M413310200 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article | Letter Note
    ​ ​Questioning the relevance of circulating cardiac progenitor cells in cardiac regeneration​
    Zimmermann, W.-H.   & Eschenhagen, T. ​ (2005) 
    Cardiovascular Research68(3) pp. 344​-346​.​ DOI: https://doi.org/10.1016/j.cardiores.2005.09.010 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article | Research Paper
    ​ ​Key role of myosin light chain (MLC) kinase-mediated MLC2a phosphorylation in the alpha(1)-adrenergic positive inotropic effect in human atrium​
    Grimm, M. ; Haas, P.; Willipinski-Stapelfeldt, B.; Zimmermann, W.-H. ; Rau, T.; Pantel, K . & Weyand, M. et al.​ (2005) 
    Cardiovascular Research65(1) pp. 211​-220​.​ DOI: https://doi.org/10.1016/j.cardiores.2004.09.019 
    Details  DOI  PMID  PMC  WoS 
  • 2004 Journal Article | Research Paper
    ​ ​S100A1 gene transfer: a strategy to strengthen engineered cardiac grafts​
    Remppis, A.; Pleger, S. T.; Most, P.; Lindenkamp, J.; Ehlermann, P.; Schweda, C. & Löffler, E. et al.​ (2004) 
    The Journal of Gene Medicine6(4) pp. 387​-394​.​ DOI: https://doi.org/10.1002/jgm.513 
    Details  DOI 
  • 2004 Journal Article | Research Paper
    ​ ​Engineered heart tissue for regeneration of diseased hearts​
    Zimmermann, W.-H. ; Melnychenko, I. & Eschenhagen, T. ​ (2004) 
    Biomaterials25(9) pp. 1639​-1647​.​ DOI: https://doi.org/10.1016/S0142-9612(03)00521-0 
    Details  DOI  PMID  PMC  WoS 
  • 2003 Journal Article
    ​ ​Heme oxygenase-1 and its reaction product, carbon monoxide, prevent inflammation-related apoptotic liver damage in mice​
    Sass, G.; Soares, M. C. P.; Yamashita, K.; Seyfried, S.; Zimmermann, W.-H. ; Eschenhagen, T.   & Kaczmarek, E. et al.​ (2003) 
    Hepatology38(4) pp. 909​-918​.​ DOI: https://doi.org/10.1002/hep.1840380417 
    Details  DOI 
  • 2003 Journal Article | Letter Note
    ​ ​Tissue engineering of aortic heart valves​
    Zimmermann, W.-H.   & Eschenhagen, T. ​ (2003) 
    Cardiovascular Research60(3) pp. 460​-462​.​ DOI: https://doi.org/10.1016/j.cardiores.2003.10.007 
    Details  DOI  PMID  PMC  WoS 
  • 2003 Journal Article | Research Paper
    ​ ​24-h Langendorff-perfused neonatal rat heart used to study the impact of adenoviral gene transfer​
    Wiechert, S.; El-Armouche, A. ; Rau, T.; Zimmermann, W.-H.   & Eschenhagen, T. ​ (2003) 
    American Journal of Physiology - Heart and Circulatory Physiology285(2) pp. H907​-H914​.​ DOI: https://doi.org/10.1152/ajpheart.00856.2002 
    Details  DOI  PMID  PMC  WoS 
  • 2003 Journal Article
    ​ ​Evidence for protein phosphatase inhibitor-1 playing an amplifier role in β-adrenergic signaling in cardiac myocytes​
    El-Armouche, A. ; Rau, T.; Zolk, O.; Ditz, D.; Pamminger, T.; Zimmermann, W.-H.   & Jäckel, E.  et al.​ (2003) 
    The FASEB Journal17(3) pp. 437​-439​.​ DOI: https://doi.org/10.1096/fj.02-0057fje 
    Details  DOI  PMID  PMC 
  • 2002 Journal Article | Research Paper
    ​ ​Cardiac Grafting of Engineered Heart Tissue in Syngenic Rats​
    Zimmermann, W.-H. ; Didié, M.; Wasmeier, G. H.; Nixdorff, U.; Hess, A.; Melnychenko, I. & Boy, O. et al.​ (2002) 
    Circulation106(12_suppl_1).​ DOI: https://doi.org/10.1161/01.cir.0000032876.55215.10 
    Details  DOI 
  • 2002 Journal Article
    ​ ​3D engineered heart tissue for replacement therapy​
    Eschenhagen, T. ; Didié, M. ; Münzel, F.; Schubert, P.; Schneiderbanger, K. & Zimmermann, W.-H. ​ (2002) 
    Basic Research in Cardiology97 pp. I146​-I152​.​ DOI: https://doi.org/10.1007/s003950200043 
    Details  DOI 
  • 2002 Journal Article | Research Paper
    ​ ​Tissue engineering of a differentiated cardiac muscle construct​
    Zimmermann, W.-H. ; Schneiderbanger, K.; Schubert, P.; Didié, M. ; Münzel, F.; Heubach, J. & Kostin, S. et al.​ (2002) 
    Circulation Research90(2) pp. 223​-230​.​ DOI: https://doi.org/10.1161/hh0202.103644 
    Details  DOI  PMID  PMC  WoS 
  • 2002 Journal Article | Research Paper
    ​ ​Cardiac tissue engineering​
    Eschenhagen, T. ; Didie, M. ; Heubach, J.; Ravens, U. & Zimmermann, W.-H. ​ (2002) 
    Transplant Immunology9(2-4) art. PII S0966-3274(02)00011-4​.​ DOI: https://doi.org/10.1016/S0966-3274(02)00011-4 
    Details  DOI  PMID  PMC  WoS 
  • 2000 Journal Article | Research Paper
    ​ ​Three-dimensional engineered heart tissue from neonatal rat cardiac myocytes​
    Zimmermann, W. H. ; Fink, C.; Kralisch, D.; Remmers, U.; Weil, J. & Eschenhagen, T. ​ (2000) 
    Biotechnology and Bioengineering68(1) pp. 106​-114​.​ DOI: https://doi.org/10.1002/(SICI)1097-0290(20000405)68:1<106::AID-BIT13>3.0.CO;2-3 
    Details  DOI  WoS 
  • 1997 Journal Article | Research Paper
    ​ ​Three-dimensional reconstitution of embryonic cardiomyocytes in a collagen matrix: a new heart muscle model system​
    Eschenhagen, T. ; Fink, C.; Remmers, U.; Scholz, H.; Wattchow, J.; Weil, J. & Zimmermann, W.-H.  et al.​ (1997) 
    The FASEB journal11(8) pp. 683​-694​.​ DOI: https://doi.org/10.1096/fasebj.11.8.9240969 
    Details  DOI  PMID  PMC  WoS 

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