Prof. Dr. Heike Bickeböller

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  • 2021 | Journal Article
    ​ ​Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model​
    Hung, R. J.; Warkentin, M. T.; Brhane, Y.; Chatterjee, N.; Christiani, D. C.; Landi, M. T. & Caporaso, N. E. et al.​ (2021) 
    Cancer Research, 81(6) pp. 1607​-1615​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-20-1237 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization​
    Zhou, W.; Liu, G.; Hung, R. J.; Haycock, P. C.; Aldrich, M. C.; Andrew, A. S. & Arnold, S. M. et al.​ (2020) 
    International Journal of Cancer, 148(5) pp. 1077​-1086​.​ DOI: https://doi.org/10.1002/ijc.33292 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Genome‐wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk​
    Dai, J.; Huang, M.; Amos, C. I.; Hung, R. J.; Tardon, A.; Andrew, A. & Chen, C. et al.​ (2020) 
    International Journal of Cancer, 146(10) pp. 2855​-2864​.​ DOI: https://doi.org/10.1002/ijc.32698 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma​
    Qin, N.; Li, Y.; Wang, C.; Zhu, M.; Dai, J.; Hong, T. & Albanes, D. et al.​ (2020) 
    Frontiers of Medicine,.​ DOI: https://doi.org/10.1007/s11684-020-0779-4 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Association Analysis of Driver Gene–Related Genetic Variants Identified Novel Lung Cancer Susceptibility Loci with 20,871 Lung Cancer Cases and 15,971 Controls​
    Wang, Y.; Gorlova, O. Y.; Gorlov, I. P.; Zhu, M.; Dai, J.; Albanes, D. & Lam, S. et al.​ (2020) 
    Cancer Epidemiology Biomarkers & Prevention, 29(7) pp. 1423​-1429​.​ DOI: https://doi.org/10.1158/1055-9965.EPI-19-1085 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility​
    Kachuri, L.; Johansson, M.; Rashkin, S. R.; Graff, R. E.; Bossé, Y.; Manem, V. & Caporaso, N. E. et al.​ (2020) 
    Nature Communications, 11(1).​ DOI: https://doi.org/10.1038/s41467-019-13855-2 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Transcriptome-wide association study reveals candidate causal genes for lung cancer​
    Bossé, Y.; Li, Z.; Xia, J.; Manem, V.; Carreras-Torres, R.; Gabriel, A. & Gaudreault, N. et al.​ (2019) 
    International Journal of Cancer,.​ DOI: https://doi.org/10.1002/ijc.32771 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article
    ​ ​Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis​
    Zhu, Y.; Wei, Y.; Zhang, R.; Dong, X.; Shen, S.; Zhao, Y. & Bai, J. et al.​ (2019) 
    Cancer Epidemiology, Biomarkers & Prevention, 28(5) pp. 935​-942​.​ DOI: https://doi.org/10.1158/1055-9965.EPI-18-0356 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers​
    Kachuri, L.; Saarela, O.; Bojesen, S. E.; Davey Smith, G.; Liu, G.; Landi, M. T. & Caporaso, N. E et al.​ (2018) 
    International Journal of Epidemiology, 48(3) pp. 751​-766​.​ DOI: https://doi.org/10.1093/ije/dyy140 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners​
    Rosenberger, A. ; Hung, R. J.; Christiani, D. C.; Caporaso, N. E.; Liu, G.; Bojesen, S. E. & Le Marchand, L. et al.​ (2018) 
    International Archives of Occupational and Environmental Health, 91(8) pp. 937​-950​.​ DOI: https://doi.org/10.1007/s00420-018-1334-3 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity​
    Ferreiro-Iglesias, A.; Lesseur, C.; McKay, J.; Hung, R. J.; Han, Y.; Zong, X. & Christiani, D. et al.​ (2018) 
    Nature Communications, 9(1).​ DOI: https://doi.org/10.1038/s41467-018-05890-2 
    ​Details  DOI 
  • 2017 | Conference Paper
    ​ ​Abstract 2292: Lung function and lung cancer risk: a Mendelian randomization study of UK Biobank cohort and the International Lung Cancer Consortium​
    Kachuri, L.; Johansson, M.; Brennan, P.; Haycock, P.; Liu, G.; Landi, M. T. & Christiani, D. C. et al.​ (2017)
    pp. 2292​-2292. ​Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC​
    American Association for Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2017-2292 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population​
    Li, Y.; Xiao, X.; Han, Y.; Gorlova, O.; Qian, D.; Leighl, N. & Johansen, J. S et al.​ (2017) 
    Carcinogenesis, 39(3) pp. 336​-346​.​ DOI: https://doi.org/10.1093/carcin/bgx113 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study.​
    Carreras-Torres, R.; Johansson, M.; Haycock, P. C.; Wade, K. H.; Relton, C. L.; Martin, R. M. & Davey Smith, G. et al.​ (2017) 
    PloS one, 12(6) art. e0177875​.​ DOI: https://doi.org/10.1371/journal.pone.0177875 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Susceptibility Loci of CNOT6 in the General mRNA Degradation Pathway and Lung Cancer Risk-A Re-Analysis of Eight GWASs​
    Zhou, F.; Wang, Y.; Liu, H.; Ready, N.; Han, Y.; Hung, R. J. & Brhane, Y. et al.​ (2017) 
    Molecular Carcinogenesis, 56(4) pp. 1227​-1238​.​ DOI: https://doi.org/10.1002/mc.22585 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls (vol 132, pg 579, 2013)​
    Brenner, D. R.; Brennan, P. C.; Boffetta, P.; Amos, C. I.; Spitz, M. R.; Chen, C. & Goodman, G. et al.​ (2016) 
    Human Genetics, 135(8).​ DOI: https://doi.org/10.1007/s00439-016-1692-4 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls​
    Brenner, D. R.; Brennan, P. C.; Boffetta, P.; Amos, C. I.; Spitz, M. R.; Chen, C. & Goodman, G. et al.​ (2013) 
    Human Genetics, 132(5) pp. 579​-589​.​ DOI: https://doi.org/10.1007/s00439-013-1270-y 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | 
    ​ ​Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls​
    Timofeeva, M. N.; Hung, R. J.; Rafnar, T.; Christiani, D. C.; Field, J. K.; Bickeboeller, H.   & Risch, A. et al.​ (2012) 
    Human Molecular Genetics, 21(22) pp. 4980​-4995​.​ DOI: https://doi.org/10.1093/hmg/dds334 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Conference Abstract
    ​ ​A comprehensive genome-wide association study of lung cancer​
    Landi, M.; Chatterjee, N.; Yu, K.; Jacobs, K.; Bergen, A. W.; Goldin, L. R. & Goldstein, A. M. et al.​ (2009)
    Cancer Research, 69 
    Philadelphia​: Amer Assoc Cancer Research.
    ​Details  WoS 
  • 2009 | Journal Article
    ​ ​A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma​
    Landi, M. T.; Chatterjee, N.; Yu, K.; Goldin, L. R.; Goldstein, A. M.; Rotunno, M. & Mirabello, L. et al.​ (2009) 
    The American Journal of Human Genetics, 85(5) pp. 679​-691​.​ DOI: https://doi.org/10.1016/j.ajhg.2009.09.012 
    ​Details  DOI  PMID  PMC  WoS 

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