Prof. Dr. Mikael Simons

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  • 2022 Journal Article | Research Paper
    ​ ​A fluorescence microscopy-based protocol for volumetric measurement of lysolecithin lesion-associated de- and re-myelination in mouse brain​
    Bosch-Queralt, M.; Tiwari, V.; Damkou, A.; Vaculčiaková, L.; Alexopoulos, I. & Simons, M. ​ (2022) 
    STAR Protocols3(1) art. 101141​.​ DOI: https://doi.org/10.1016/j.xpro.2022.101141 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper
    ​ ​Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery​
    Penkert, H.; Bertrand, A.; Tiwari, V.; Breimann, S.; Müller, S. A.; Jordan, P. M. & Gerl, M. J. et al.​ (2021) 
    Cell Reports37(4) art. 109898​.​ DOI: https://doi.org/10.1016/j.celrep.2021.109898 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper
    ​ ​Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination​
    Bosch-Queralt, M.; Cantuti-Castelvetri, L. ; Damkou, A.; Schifferer, M. ; Schlepckow, K.; Alexopoulos, I. & Lütjohann, D. et al.​ (2021) 
    Nature Metabolism3(2) pp. 211​-227​.​ DOI: https://doi.org/10.1038/s42255-021-00341-7 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper
    ​ ​TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination​
    Gouna, G.; Klose, C.; Bosch-Queralt, M.; Liu, L.; Gokce, O. ; Schifferer, M.   & Cantuti-Castelvetri, L.  et al.​ (2021) 
    Journal of Experimental Medicine218(10).​ DOI: https://doi.org/10.1084/jem.20210227 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article
    ​ ​Defective cholesterol clearance limits remyelination in the aged central nervous system​
    Cantuti-Castelvetri, L.; Fitzner, D.; Bosch-Queralt, M.; Weil, M.-T.; Su, M.; Sen, P. & Ruhwedel, T. et al.​ (2018) 
    Science359(6376) pp. 684​-688​.​ DOI: https://doi.org/10.1126/science.aan4183 
    Details  DOI 

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