Prof. Dr. Stephan Elmar Lehnart

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  • 2022 | Journal Article
    ​ ​Dysferlin facilitates the de novo biogenesis of tubular membranes in hypertrophic remodelling​
    Paulke, N.; Amlaz, S.; Fleischhacker, C.; Kohl, T.; Kownatzki-Danger, D.; Hasenfuss, G.   & Lehnart, S.  et al.​ (2022) 
    European Heart Journal, 43(Suppl. 2).​ DOI: https://doi.org/10.1093/eurheartj/ehac544.2944 
    ​Details  DOI 
  • 2022 | Journal Article | Discussion
    ​ ​New Insights into the Proteolytic Regulation of the Structural Protein Junctophilin-2 by Calpain​
    Weninger, G. & Lehnart, S. E. ​ (2022) 
    Journal of Cellular Signaling, 3(4).​ DOI: https://doi.org/10.33696/Signaling.3.081 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes​
    Brandenburg, S. ; Pawlowitz, J.; Steckmeister, V.; Subramanian, H.; Uhlenkamp, D.; Scardigli, M. & Mushtaq, M. et al.​ (2022) 
    Journal of Molecular and Cellular Cardiology, 165 pp. 141​-157​.​ DOI: https://doi.org/10.1016/j.yjmcc.2022.01.003 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Overview
    ​ ​The Role of Junctophilin Proteins in Cellular Function​
    Lehnart, S. E.   & Wehrens, X. H. T.​ (2022) 
    Physiological Reviews,.​ DOI: https://doi.org/10.1152/physrev.00024.2021 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Editorial Contribution (Editorial, Introduction, Epilogue) | 
    ​ ​Editorial: Cardiac optogenetics: Using light to observe and excite the heart​
    Bruegmann, T. ; Smith, G. L. & Lehnart, S. E. ​ (2022) 
    Frontiers in Physiology, 13 art. 1031062​.​ DOI: https://doi.org/10.3389/fphys.2022.1031062 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | 
    ​ ​Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis​
    Brandenburg, S. ; Drews, L.; Schönberger, H.-L.; Jacob, C. F.; Paulke, N. J.; Beuthner, B. E. & Topci, R. et al.​ (2022) 
    Journal of Molecular and Cellular Cardiology, 173 pp. 1​-15​.​ DOI: https://doi.org/10.1016/j.yjmcc.2022.08.363 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes​
    Weninger, G.; Pochechueva, T.; El Chami, D.; Luo, X.; Kohl, T. ; Brandenburg, S.   & Urlaub, H.  et al.​ (2022) 
    Scientific Reports, 12(1).​ DOI: https://doi.org/10.1038/s41598-022-14320-9 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool​
    Wegener, J. W.; Wagdi, A.; Wagner, E.; Katschinski, D. M.; Hasenfuß, G. ; Brügmann, T.   & Lehnart, S. E. ​ (2021) 
    Frontiers in Physiology, 12.​ DOI: https://doi.org/10.3389/fphys.2021.777770 
    ​Details  DOI  PMID  PMC 
  • 2021 | Book Chapter
    ​ ​Management of Metadata Types in Basic Cardiological Research​
    Kusch, H. ; Kossen, R. ; Suhr, M.; Freckmann, L.; Weber, L.; Henke, C.& Lehmann, C. et al.​ (2021)
    In:​Röhrig, Rainer; Beißbarth, Tim; König, Jochem; Ose, Claudia; Rauch, Geraldine; Sax, Ulrich; Schreiweis, Björn, et al.​ (Eds.), German Medical Data Sciences 2021: Digital Medicine: Recognize – Understand – Heal pp. 59​-68.  DOI: https://doi.org/10.3233/SHTI210542 
    ​Details  DOI  PMID  PMC 
  • 2021 | Preprint
    ​ ​Analyzing cross-talk between superimposed signals: Vector norm dependent hidden Markov models and applications​
    Vanegas, L. J.; Eltzner, B.; Rudolf, D. ; Dura, M.; Lehnart, S. E.  & Munk, A. ​ (2021). DOI: https://doi.org/10.48550/arXiv.2103.06071 
    ​Details  DOI  arXiv 
  • 2021 | Journal Article | Overview | 
    ​ ​Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review​
    Müllenbroich, M. C.; Kelly, A.; Acker, C.; Bub, G.; Brügmann, T. ; Di Bona, A. & Entcheva, E. et al.​ (2021) 
    Frontiers in Physiology, 12.​ DOI: https://doi.org/10.3389/fphys.2021.769586 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​CaMKII inhibition has dual effects on spontaneous Ca 2+ release and Ca 2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation​
    Sadredini, M.; Haugsten Hansen, M.; Frisk, M.; Louch, W. E.; Lehnart, S. E. ; Sjaastad, I. & Korseberg Stokke, M.​ (2021) 
    American Journal of Physiology-Heart and Circulatory Physiology, 321(2) pp. H446​-H460​.​ DOI: https://doi.org/10.1152/ajpheart.00011.2021 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper
    ​ ​Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes​
    Peper, J.; Kownatzki-Danger, D.; Weninger, G.; Seibertz, F.; Pronto, J. R. D.; Sutanto, H. & Pacheu-Grau, D. et al.​ (2021) 
    Circulation Research, 128(6).​ DOI: https://doi.org/10.1161/CIRCRESAHA.119.316547 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1​
    Sadredini, M.; Manotheepan, R.; Lehnart, S. E. ; Anderson, M. E.; Sjaastad, I. & Stokke, M. K.​ (2021) 
    Physiological Reports, 9(18) art. e15030​.​ DOI: https://doi.org/10.14814/phy2.15030 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper
    ​ ​14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban​
    Menzel, J. ; Kownatzki-Danger, D.; Tokar, S.; Ballone, A.; Unthan-Fechner, K.; Kilisch, M.   & Lenz, C.  et al.​ (2020) 
    Science Signaling, 13(647) pp. eaaz1436​.​ DOI: https://doi.org/10.1126/scisignal.aaz1436 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper
    ​ ​Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation​
    Alsina, K. M.; Hulsurkar, M.; Brandenburg, S. ; Kownatzki-Danger, D.; Lenz, C. ; Urlaub, H.   & Abu-Taha, I. et al.​ (2019) 
    Circulation, 140(8) pp. 681​-693​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.119.039642 
    ​Details  DOI  PMID  PMC 

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Project:  EXC 2067: Multiscale Bioimaging

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