Dirk Matthes

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  • 2022 | Journal Article | 
    ​ ​Antonschmidt, Leif, et al. "The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils​." ​Nature Communications, vol. 13, no. 1, ​2022, , ​doi: 10.1038/s41467-022-32797-w. 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Matthes, Dirk, et al. "Resolving the Atomistic Modes of Anle138b Inhibitory Action on Peptide Oligomer Formation​." ​ASC Chemical Neuroscience, vol. 8, no. 12, ​2017, pp. 2791​-2808​, ​doi: 10.1021/acschemneuro.7b00325. 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article
    ​ ​Matthes, Dirk, et al. "Global and Local Conformational Heterogeniety Governs the Pre-Nucleation Phase in Amyloidogenic Self-Assembly​." ​Biophysical Journal, vol. 110, no. 3, ​2016, p. 402a​, ​doi: 10.1016/j.bpj.2015.11.2170. 
    ​Details  DOI 
  • 2016 | Journal Article | 
    ​ ​Matthes, Dirk, et al. "An Atomistic View of Amyloidogenic Self-assembly: Structure and Dynamics of Heterogeneous Conformational States in the Pre-nucleation Phase​." ​Scientific Reports, vol. 6, no. 1, ​2016, , ​doi: 10.1038/srep33156. 
    ​Details  DOI 
  • 2014 | Journal Article | 
    ​ ​Matthes, Dirk, et al. "Spontaneous Aggregation of the Insulin-Derived Steric Zipper Peptide VEALYL Results in Different Aggregation Forms with Common Features​." ​Journal of Molecular Biology, vol. 426, no. 2, ​2014, pp. 362​-376​, ​doi: 10.1016/j.jmb.2013.10.020. 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​Matthes, Dirk, Vytautas Gapsys, and Bert L. de Groot. "Driving Forces and Structural Determinants of Steric Zipper Peptide Oligomer Formation Elucidated by Atomistic Simulations​." ​Journal of Molecular Biology, vol. 421, no. 2-3, ​2012, pp. 390​-416​, ​doi: 10.1016/j.jmb.2012.02.004. 
    ​Details  DOI 
  • 2011 | Journal Article
    ​ ​Matthes, Dirk, et al. "Mapping the Conformational Dynamics and Pathways of Spontaneous Steric Zipper Peptide Oligomerization​." ​PLoS One, vol. 6, no. 5, ​2011, p. e19129​, ​doi: 10.1371/journal.pone.0019129. 
    ​Details  DOI 
  • 2010 | Journal Article
    ​ ​Matthes, Dirk, and Bert L. de Groot. "The Spontaneous Aggregation of Steric Zipper Peptides Studied by Molecular Dynamics Simulations​." ​Biophysical Journal, vol. 98, no. 3, ​2010, p. 650a​, ​doi: 10.1016/j.bpj.2009.12.3561. 
    ​Details  DOI 
  • 2009 | Journal Article
    ​ ​Haas, Jürgen, et al. "Inside Cover: Primary Steps of pH‐Dependent Insulin Aggregation Kinetics are Governed by Conformational Flexibility (ChemBioChem 11/2009)​." ​ChemBioChem, vol. 10, no. 11, ​2009, p. 1742​, ​doi: 10.1002/cbic.200990042. 
    ​Details  DOI 
  • 2009 | Journal Article
    ​ ​Haas, Jürgen, et al. "Primary Steps of pH-Dependent Insulin Aggregation Kinetics are Governed by Conformational Flexibility​." ​ChemBioChem, vol. 10, no. 11, ​2009, pp. 1816​-1822​, ​doi: 10.1002/cbic.200900266. 
    ​Details  DOI 
  • 2009 | Journal Article
    ​ ​Matthes, Dirk, and Bert L. de Groot. "Secondary Structure Propensities in Peptide Folding Simulations: A Systematic Comparison of Molecular Mechanics Interaction Schemes​." ​Biophysical Journal, vol. 97, no. 2, ​2009, pp. 599​-608​, ​doi: 10.1016/j.bpj.2009.04.061. 
    ​Details  DOI 

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