Dr. rer. nat. Ellen Gerhardt

 
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  • 2022 Journal Article | Research Paper
    ​ ​Brás, Inês C., Mohammad H. Khani, Dietmar Riedel, Iwan Parfentev, Ellen Gerhardt, Christoph van Riesen, Henning Urlaub, Tim Gollisch, and Tiago F. Outeiro. "Ectosomes and exosomes modulate neuronal spontaneous activity​." ​Journal of Proteomics ​269 (2022): ​104721​. ​https://doi.org/10.1016/j.jprot.2022.104721.
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  • 2022 Journal Article | Research Paper | 
    ​ ​Torres-Garcia, Laura, Joana M. P. Domingues, Edoardo Brandi, Caroline Haikal, Janitha M. Mudannayake, Inês C. Brás, Ellen Gerhardt et al. "Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation​." ​Scientific Reports ​12, no. 1 (2022): ​2987​. ​https://doi.org/10.1038/s41598-022-06846-9.
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  • 2022 Journal Article
    ​ ​Brás, Inês C., Mohammad H. Khani, Eftychia Vasili, Wiebke Möbius, Dietmar Riedel, Iwan Parfentev, Ellen Gerhardt et al. "Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity​." ​Journal of Parkinson's Disease (2022): ​1​-26​. ​https://doi.org/10.3233/JPD-223516.
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  • 2020 Journal Article | Overview | 
    ​ ​Brás, Inês Caldeira, Antonio Dominguez‐Meijide, Ellen Gerhardt, David Koss, Diana F. Lázaro, Patrícia I. Santos, Eftychia Vasili, Mary Xylaki, and Tiago Fleming Outeiro. "Synucleinopathies: Where we are and where we need to go​." ​Journal of Neurochemistry ​153, no. 4 (2020): ​433​-454​. ​https://doi.org/10.1111/jnc.14965.
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  • 2019 Journal Article | Overview
    ​ ​Outeiro, Tiago Fleming, Kirsten Harvey, Antonio Dominguez-Meijide, and Ellen Gerhardt. "LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders?​." ​Biochemical Society Transactions ​47, no. 3 (2019): ​827​-838​. ​https://doi.org/10.1042/BST20180466.
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  • 2019 Journal Article
    ​ ​Brasil, Aline de Araújo, Mariana Dias Castela de Carvalho, Ellen Gerhardt, Daniela Dias Queiroz, Marcos Dias Pereira, Tiago Fleming Outeiro, and Elis Cristina Araujo Eleutherio. "Characterization of the activity, aggregation, and toxicity of heterodimers of WT and ALS-associated mutant Sod1​." ​Proceedings of the National Academy of Sciences of the United States of America ​116, no. 51 (2019): ​25991​-26000​. ​https://doi.org/10.1073/pnas.1902483116.
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  • 2017 Journal Article
    ​ ​Marciniak, Elodie, Antoine Leboucher, Emilie Caron, Tariq Ahmed, Anne Tailleux, Julie Dumont, Tarik Issad et al. "Tau deletion promotes brain insulin resistance​." ​Journal of Experimental Medicine ​214, no. 8 (2017): ​2257​-2269​. ​https://doi.org/10.1084/jem.20161731.
    Details  DOI 
  • 2017 Journal Article
    ​ ​Paiva, Isabel, Raquel Pinho, Maria Angeliki Pavlou, Magali Hennion, Pauline Wales, Anna-Lena Schütz, Ashish Rajput et al. "Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage​." ​Human Molecular Genetics ​26, no. 12 (2017): ​2231​-2246​. ​https://doi.org/10.1093/hmg/ddx114.
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  • 2017 Journal Article | 
    ​ ​Brasil, Aline A., Rayne S. S. Magalhães, Mariana D. C. De Carvalho, Isabel Paiva, Ellen Gerhardt, Marcos D. Pereira, Tiago F. Outeiro, and Elis C. A. Eleutherio. "Implications of fALS Mutations on Sod1 Function and Oligomerization in Cell Models​." ​Molecular Neurobiology ​55, no. 6 (2017): ​5269​-5281​. ​https://doi.org/10.1007/s12035-017-0755-4.
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  • 2016 Journal Article
    ​ ​Guerreiro, P. S., E. Gerhardt, T. L. Da Fonseca, M. Bähr, T. F. Outeiro, and Katrin Eckermann. "LRRK2 Promotes Tau Accumulation, Aggregation and Release​." ​Molecular Neurobiology ​53, no. 5 (2016): ​3124​-3135​. ​https://doi.org/10.1007/s12035-015-9209-z.
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  • 2016 Journal Article
    ​ ​Tenreiro, Sandra, Rita Rosado-Ramos, Ellen Gerhardt, Filippo Favretto, Filipa Magalhães, Blagovesta Popova, Stefan Becker, Markus Zweckstetter, Gerhard H. Braus, and Tiago Fleming Outeiro. "Yeast reveals similar molecular mechanisms underlying alpha- and beta-synuclein toxicity​." ​Human Molecular Genetics ​25, no. 2 (2016): ​275​-290​. ​https://doi.org/10.1093/hmg/ddv470.
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  • 2014 Journal Article | Research Paper | 
    ​ ​Lazaro, Diana F., Eva F. Rodrigues, Ramona Langohr, Hedieh Shahpasandzadeh, Thales Ribeiro, Patricia Guerreiro, Ellen Gerhardt et al. "Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation​." ​PLoS Genetics ​10 (2014): ​e1004741​. ​https://doi.org/10.1371/journal.pgen.1004741.
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  • 2002 Journal Article | Research Paper
    ​ ​Straten, G, C. Schmeer, A. Kretz, Ellen Gerhardt, S. Kugler, Joerg B. Schulz, C. Gravel, Mathias Bähr, and Stefan Isenmann. "Potential synergistic protection of retinal ganglion cells from axotomy-induced apoptosis by adenoviral administration of glial cell line-derived neurotrophic factor and X-chromosome-linked inhibitor of apoptosis​." ​Neurobiology of Disease ​11, no. 1 (2002): ​123​-133​. ​https://doi.org/10.1006/nbdi.2002.0543.
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  • 2001 Journal Article | Research Paper
    ​ ​Gerhardt, Ellen, S. Kugler, Marcel Leist, C. Beier, L. Berliocchi, C. Volbracht, M Weller, Mathias Bähr, P. Nicotera, and Joerg B. Schulz. "Cascade of caspase activation in potassium-deprived cerebellar granule neurons: Targets for treatment with peptide and protein inhibitors of apoptosis​." ​Molecular and Cellular Neuroscience ​17, no. 4 (2001): ​717​-731​. ​https://doi.org/10.1006/mcne.2001.0962.
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  • 2001 Journal Article | Research Paper
    ​ ​Kügler, S., L. Meyn, H. Holzmüller, E. Gerhardt, S. Isenmann, J. B. Schulz, and M. Bähr. "Neuron-specific expression of therapeutic proteins: Evaluation of different cellular promoters in recombinant adenoviral vectors​." ​Molecular and Cellular Neuroscience ​17, no. 1 (2001): ​78​-96​. ​https://doi.org/10.1006/mcne.2000.0929.
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  • 2000 Journal Article | Research Paper
    ​ ​Eberhardt, O., Rainer V. Coelln, S. Kugler, J. Lindenau, S Rathke-Hartlieb, Ellen Gerhardt, S. Haid et al. "Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease​." ​The Journal of Neuroscience ​20, no. 24 (2000): ​9126​-9134​. ​https://doi.org/10.1523/JNEUROSCI.20-24-09126.2000.
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