Dr. rer. nat. Laura Cecilia Zelarayán

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  • 2021 | Journal Article | Research Paper | 
    ​ ​Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression​
    Schoger, E.; Zimmermann, W.-H. ; Cyganek, L.   & Zelarayán, L. C. ​ (2021) 
    Stem Cell Research, 55 art. S1873506121003202​.​ DOI: https://doi.org/10.1016/j.scr.2021.102473 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation​
    Schoger, E.; Zimmermann, W.-H. ; Cyganek, L.   & Zelarayán, L. C. ​ (2021) 
    Stem Cell Research, 56 art. S1873506121003652​.​ DOI: https://doi.org/10.1016/j.scr.2021.102518 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper
    ​ ​Inhibition of Prolyl-Hydroxylase Domain Enzymes Protects From Reoxygenation Injury in Engineered Human Myocardium​
    Levent, E. ; Noack, C. ; Zelarayán, L. C. ; Katschinski, D. M. ; Zimmermann, W.-H.   & Tiburcy, M. ​ (2020) 
    Circulation, 142(17) pp. 1694​-1696​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.119.044471 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper
    ​ ​CRISPR-Mediated Activation of Endogenous Gene Expression in the Postnatal Heart​
    Schoger, E.; Carroll, K. J.; Iyer, L. M. ; McAnally, J. R.; Tan, W.; Liu, N. & Noack, C.  et al.​ (2020) 
    Circulation Research, 126(1) pp. 6​-24​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.118.314522 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper | 
    ​ ​Agonistic and antagonistic roles of fibroblasts and cardiomyocytes on viscoelastic stiffening of engineered human myocardium​
    Schlick, S. F. ; Spreckelsen, F.; Tiburcy, M. ; Iyer, L. M. ; Meyer, T. ; Zelarayan, L. C.   & Luther, S.  et al.​ (2019) 
    Progress in Biophysics and Molecular Biology, 144 pp. 51​-60​.​ DOI: https://doi.org/10.1016/j.pbiomolbio.2018.11.011 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Research Paper | 
    ​ ​KLF15-Wnt–Dependent Cardiac Reprogramming Up-Regulates SHISA3 in the Mammalian Heart​
    Noack, C. ; Iyer, L. M. ; Liaw, N. Y. ; Schoger, E.; Khadjeh, S. ; Wagner, E.   & Woelfer, M. et al.​ (2019) 
    Journal of the American College of Cardiology, 74(14) pp. 1804​-1819​.​ DOI: https://doi.org/10.1016/j.jacc.2019.07.076 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | Research Paper | 
    ​ ​Generation of a KLF15 homozygous knockout human embryonic stem cell line using paired CRISPR/Cas9n, and human cardiomyocytes derivation​
    Noack, C. ; Haupt, L. P. ; Zimmermann, W.-H. ; Streckfuss-Bömeke, K.   & Zelarayán, L. C. ​ (2017) 
    Stem Cell Research, 23 pp. 127​-131​.​ DOI: https://doi.org/10.1016/j.scr.2017.07.007 
    ​Details  DOI  PMID  PMC 
  • 2014 | Journal Article | Research Paper | 
    ​ ​Erythropoietin Responsive Cardiomyogenic Cells Contribute to Heart Repair Post Myocardial Infarction​
    Zafiriou, M. P. ; Noack, C. ; Unsoeld, B. W.; Didie, M. ; Pavlova, E.; Fischer, H. J.   & Reichardt, H. M.  et al.​ (2014) 
    STEM CELLS, 32(9) pp. 2480​-2491​.​ DOI: https://doi.org/10.1002/stem.1741 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Research Paper | 
    ​ ​The Four and a Half LIM-Domain 2 Controls Early Cardiac Cell Commitment and Expansion Via Regulating β-Catenin-Dependent Transcription​
    Renger, A.; Zafiriou, M.-P. ; Noack, C. ; Pavlova, E.; Becker, A. ; Sharkova, K. & Bergmann, M. W. et al.​ (2013) 
    Stem Cells, 31(5) pp. 928​-940​.​ DOI: https://doi.org/10.1002/stem.1332 
    ​Details  DOI  PMID  PMC  WoS 

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Project:  SFB 1002 | C04: Fibroblasten-Kardiomyozyten Interaktion im gesunden und erkrankten Herzen: Mechanismen und therapeutische Interventionen bei Kardiofibroblastopathien

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