Dr. med. Dr. rer. nat. Lena-Christin Conradi

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  • 2023 | Journal Article | 
    ​ ​Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution​
    Fleischer, J. R.; Schmitt, A. M.; Haas, G.; Xu, X.; Zeisberg, E. M.; Bohnenberger, H. & Küffer, S. et al.​ (2023) 
    Molecular Cancer, 22(1) art. 17​.​ DOI: https://doi.org/10.1186/s12943-023-01713-1 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Comparing Apparent Diffusion Coefficient and FNCLCC Grading to Improve Pretreatment Grading of Soft Tissue Sarcoma—A Translational Feasibility Study on Fusion Imaging​
    Hettler, M.; Kitz, J. ; Hosseini, A. S. A. ; Guhlich, M.; Panahi, B.; Ernst, J.   & Conradi, L.-C.  et al.​ (2022) 
    Cancers, 14(17) pp. 4331​.​ DOI: https://doi.org/10.3390/cancers14174331 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Late-stage stitching enabled by manganese-catalyzed C─H activation: Peptide ligation and access to cyclopeptides​
    Kaplaneris, N.; Kaltenhӓuser, F.; Sirvinskaite, G.; Fan, S.; De Oliveira, T.; Conradi, L.-C.   & Ackermann, L. ​ (2021) 
    Science Advances, 7(9) pp. eabe6202​.​ DOI: https://doi.org/10.1126/sciadv.abe6202 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo​
    De Oliveira, T.; Goldhardt, T.; Edelmann, M.; Rogge, T. ; Rauch, K. ; Kyuchukov, N. D. & Menck, K.  et al.​ (2021) 
    Cancers, 13(5) pp. 1011​.​ DOI: https://doi.org/10.3390/cancers13051011 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​NOTCH Activation via gp130/STAT3 Signaling Confers Resistance to Chemoradiotherapy​
    Koerdel, K.; Spitzner, M. ; Meyer, T. ; Engels, N.; Krause, F.; Gaedcke, J.   & Conradi, L.-C.  et al.​ (2021) 
    Cancers, 13(3) pp. 455​.​ DOI: https://doi.org/10.3390/cancers13030455 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates​
    Goveia, J.; Rohlenova, K.; Taverna, F.; Treps, L.; Conradi, L.-C. ; Pircher, A. & Geldhof, V. et al.​ (2020) 
    Cancer Cell, 37(1) pp. 21​-36.e13​.​ DOI: https://doi.org/10.1016/j.ccell.2019.12.001 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis​
    Rohlenova, K.; Goveia, J.; García-Caballero, M.; Subramanian, A.; Kalucka, J.; Treps, L. & Falkenberg, K. D. et al.​ (2020) 
    Cell Metabolism, 31(4) pp. 862​-877.e14​.​ DOI: https://doi.org/10.1016/j.cmet.2020.03.009 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​EndoDB: a database of endothelial cell transcriptomics data​
    Khan, S.; Taverna, F.; Rohlenova, K.; Treps, L.; Geldhof, V.; de Rooij, L. & Sokol, L. et al.​ (2018) 
    Nucleic Acids Research, 47(D1) pp. D736​-D744​.​ DOI: https://doi.org/10.1093/nar/gky997 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion​
    Schulz-Heddergott, R. ; Stark, N. ; Edmunds, S. J. ; Li, J.; Conradi, L.-C. ; Bohnenberger, H.   & Ceteci, F. et al.​ (2018) 
    Cancer Cell, 34(2) pp. 298​-314.e7​.​ DOI: https://doi.org/10.1016/j.ccell.2018.07.004 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Simultaneous inhibition of IGF1R and EGFR enhances the efficacy of standard treatment for colorectal cancer by the impairment of DNA repair and the induction of cell death​
    Oberthür, R.; Seemann, H. ; Gehrig, J. ; Rave-Fränk, M. ; Bremmer, F. ; Halpape, R.   & Conradi, L.-C.  et al.​ (2017) 
    Cancer Letters, 407 pp. 93​-105​.​ DOI: https://doi.org/10.1016/j.canlet.2017.08.009 
    ​Details  DOI 
  • 2016 | Conference Abstract
    ​ ​The prognostic role of the host immune response in rectal cancer patients treated with neoadjuvant chemoradiation.​
    Sprenger, T. ; Wirtz, R. M; Pektas, S.; Bohnenberger, H. ; Kauffels, A. ; Conradi, L.-C.   & Homayounfar, K.  et al.​ (2016)
    34(4) pp. 575​-575. ​Gastrointestinal Cancers Symposium​, San Francisco, CA.
    Alexandria​: Amer Soc Clinical Oncology. DOI: https://doi.org/10.1200/jco.2016.34.4_suppl.575 
    ​Details  DOI  WoS 
  • 2016 | Journal Article
    ​ ​Stage-Dependent Frequency of Lymph Node Metastases in Patients With Rectal Carcinoma After Preoperative Chemoradiation: Results from the CAO/ARO/AIO-94 Trial and From a Comparative Prospective Evaluation With Extensive Pathological Workup​
    Sprenger, T. ; Rothe, H.; Conradi, L.-C. ; Beissbarth, T. ; Kauffels, A. ; Kitz, J.   & Homayounfar, K.  et al.​ (2016) 
    Diseases of the Colon & Rectum, 59(5) pp. 377​-385​.​ DOI: https://doi.org/10.1097/DCR.0000000000000570 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper | 
    ​ ​STED Super-Resolution Microscopy of Clinical Paraffin-Embedded Human Rectal Cancer Tissue​
    Ilgen, P. ; Stoldt, S. ; Conradi, L.-C. ; Wurm, C. A. ; Rüschoff, J. ; Ghadimi, B. M.   & Liersch, T.  et al.​ (2014) 
    PLOS ONE, 9(7) art. e101563​.​ DOI: https://doi.org/10.1371/journal.pone.0101563 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | 
    ​ ​Metastatic recurrence after complete resection of colorectal liver metastases: impact of surgery and chemotherapy on survival​
    Homayounfar, K. ; Bleckmann, A. ; Conradi, L.-C. ; Sprenger, T.; Lorf, T.; Niessner, M.   & Sahlmann, C.-O.  et al.​ (2013) 
    International Journal of Colorectal Disease, 28(7) pp. 1009​-1017​.​ DOI: https://doi.org/10.1007/s00384-013-1648-2 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | 
    ​ ​Bilobar spreading of colorectal liver metastases does not significantly affect survival after R0 resection in the era of interdisciplinary multimodal treatment​
    Homayounfar, K. ; Bleckmann, A. ; Conradi, L.-C. ; Sprenger, T.; Beißbarth, T. ; Lorf, T.   & Niessner, M.  et al.​ (2012) 
    International Journal of Colorectal Disease, 27(10) pp. 1359​-1367​.​ DOI: https://doi.org/10.1007/s00384-012-1455-1 
    ​Details  DOI  PMID  PMC  WoS 

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