Prof. Dr. Tim Beißbarth

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  • 2022 | Journal Article | Research Paper | 
    ​ ​High-Throughput Profiling of Colorectal Cancer Liver Metastases Reveals Intra- and Inter-Patient Heterogeneity in the EGFR and WNT Pathways Associated with Clinical Outcome​
    Menck, K.; Wlochowitz, D.; Wachter, A.; Conradi, L.-C.; Wolff, A.; Scheel, A. H. & Korf, U. et al.​ (2022) 
    Cancers, 14(9).​ DOI: https://doi.org/10.3390/cancers14092084 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Measurement invariance of six language versions of the post-traumatic stress disorder checklist for DSM-5 in civilians after traumatic brain injury​
    Bockhop, F.; Zeldovich, M.; Cunitz, K.; Van Praag, D.; van der Vlegel, M.; Beißbarth, T.   & Hagmayer, Y. et al.​ (2022) 
    Scientific Reports, 12(1).​ DOI: https://doi.org/10.1038/s41598-022-20170-2 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper
    ​ ​Master Regulators Associated with Poor Prognosis in Glioblastoma Multiforme​
    Kalya, M.; Beißbarth, T.   & Kel, A. E.​ (2021) 
    Biochemistry (Moscow). Supplemental Series B, Biomedical Chemistry, 15(4) pp. 263​-273​.​ DOI: https://doi.org/10.1134/S1990750821040077 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​A prediction-based method to estimate student learning outcome: Impact of response rate and gender differences on evaluation results​
    Grebener, B.-L.; Barth, J.; Anders, S. ; Beißbarth, T.   & Raupach, T. ​ (2021) 
    Medical Teacher, pp. 1​-12​.​ DOI: https://doi.org/10.1080/0142159X.2020.1867714 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo​
    De Oliveira, T.; Goldhardt, T.; Edelmann, M.; Rogge, T. ; Rauch, K. ; Kyuchukov, N. D. & Menck, K.  et al.​ (2021) 
    Cancers, 13(5) pp. 1011​.​ DOI: https://doi.org/10.3390/cancers13051011 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Coordinated regulation of WNT/β-catenin, c-Met, and integrin signalling pathways by miR-193b controls triple negative breast cancer metastatic traits​
    Giacomelli, C.; Jung, J.; Wachter, A.; Ibing, S.; Will, R.; Uhlmann, S. & Mannsperger, H. et al.​ (2021) 
    BMC Cancer, 21(1) art. 1296​.​ DOI: https://doi.org/10.1186/s12885-021-08955-6 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​NOTCH Activation via gp130/STAT3 Signaling Confers Resistance to Chemoradiotherapy​
    Koerdel, K.; Spitzner, M. ; Meyer, T. ; Engels, N.; Krause, F.; Gaedcke, J.   & Conradi, L.-C.  et al.​ (2021) 
    Cancers, 13(3) pp. 455​.​ DOI: https://doi.org/10.3390/cancers13030455 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Effect of the Lymphocyte Activation Gene 3 Polymorphism rs951818 on Mortality and Disease Progression in Patients with Sepsis—A Prospective Genetic Association Study​
    Mewes, C.; Alexander, T.; Büttner, B.; Hinz, J.; Alpert, A.; Popov, A.-F. & Beißbarth, T.  et al.​ (2021) 
    Journal of Clinical Medicine, 10(22) pp. 5302​.​ DOI: https://doi.org/10.3390/jcm10225302 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Text mining-based word representations for biomedical data analysis and protein-protein interaction networks in machine learning tasks​
    Alachram, H.; Chereda, H.; Beißbarth, T. ; Wingender, E.   & Stegmaier, P.​ (2021) 
    PLoS One, 16(10) art. e0258623​.​ DOI: https://doi.org/10.1371/journal.pone.0258623 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​IGFBP2 Is a Potential Master Regulator Driving the Dysregulated Gene Network Responsible for Short Survival in Glioblastoma Multiforme​
    Kalya, M.; Kel, A.; Wlochowitz, D.; Wingender, E.   & Beißbarth, T. ​ (2021) 
    Frontiers in Genetics, 12 art. 670240​.​ DOI: https://doi.org/10.3389/fgene.2021.670240 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Antibody signatures in patients with histopathologically defined multiple sclerosis patterns​
    Stork, L.; Ellenberger, D.; Ruprecht, K.; Reindl, M.; Beißbarth, T. ; Friede, T. & Kümpfel, T. et al.​ (2020) 
    Acta Neuropathologica, 139(3) pp. 547​-564​.​ DOI: https://doi.org/10.1007/s00401-019-02120-x 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article
    ​ ​Clinical application of genomic high-throughput data: Infrastructural, ethical, legal and psychosocial aspects​
    Umbach, N.; Beißbarth, T. ; Bleckmann, A.; Duttge, G.; Flatau, L.; König, A. & Kuhn, J. et al.​ (2020) 
    European Neuropsychopharmacology, 31 pp. 1​-15​.​ DOI: https://doi.org/10.1016/j.euroneuro.2019.09.008 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article
    ​ ​Intensified Histopathological Work-Up after Pancreatic Head Resection Reveals Relevant Prognostic Markers​
    Dusch, N.; Oldani, M.; Steffen, T.; Kitz, J. ; Koenig, U.; Azizian, A.   & König, A. et al.​ (2020) 
    Digestion, pp. 1​-9​.​ DOI: https://doi.org/10.1159/000504648 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article
    ​ ​Molecular Characterization of Different Histopathological Growth Patterns in Colorectal Cancer Liver Metastases​
    Haas, G.; De Oliveira, T.; Wachter, A.; Menck, K.; Bohnenberger, H.; Edelmann, M. & Goldhardt, T. et al.​ (2020) 
    European Journal of Surgical Oncology, 46(2) art. e77​.​ DOI: https://doi.org/10.1016/j.ejso.2019.11.175 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​The long-term influence of hospital and surgeon volume on local control and survival in the randomized German Rectal Cancer Trial CAO/ARO/AIO-94​
    Sprenger, T. ; Beißbarth, T. ; Sauer, R.; Tschmelitsch, J.; Fietkau, R.; Hohenberger, W. & Staib, L. et al.​ (2020) 
    Surgical Oncology, 35 pp. 200​-205​.​ DOI: https://doi.org/10.1016/j.suronc.2020.08.021 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Impact of pre-OP independence in patients with limited brain metastases on long-term survival​
    Bleckmann, A. ; Kirchner, B.; Nietert, M. ; Peeck, M.; Balkenhol, M.; Egert, D. & Rohde, T. V. et al.​ (2020) 
    BMC Cancer, 20(1).​ DOI: https://doi.org/10.1186/s12885-020-07459-z 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Discriminating malignant and benign clinical T1 renal masses on computed tomography​
    Uhlig, J.; Biggemann, L.; Nietert, M. M. ; Beißbarth, T. ; Lotz, J. ; Kim, H. S. & Trojan, L.  et al.​ (2020) 
    Medicine, 99(16) pp. e19725​.​ DOI: https://doi.org/10.1097/MD.0000000000019725 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​TIM-3 Genetic Variants Are Associated with Altered Clinical Outcome and Susceptibility to Gram-Positive Infections in Patients with Sepsis​
    Mewes, C.; Alexander, T.; Büttner, B. ; Hinz, J. ; Alpert, A.; Popov, A.-F. & Ghadimi, M.  et al.​ (2020) 
    International Journal of Molecular Sciences, 21(21) pp. 8318​.​ DOI: https://doi.org/10.3390/ijms21218318 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Constructing temporal regulatory cascades in the context of development and cell differentiation​
    Daou, R.; Beißbarth, T. ; Wingender, E. ; Gültas, M. & Haubrock, M. ​ (2020) 
    PLoS One, 15(4) pp. e0231326​.​ DOI: https://doi.org/10.1371/journal.pone.0231326 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Favorable 90-Day Mortality in Obese Caucasian Patients with Septic Shock According to the Sepsis-3 Definition​
    Mewes, C.; Böhnke, C.; Alexander, T.; Popov, A.-F.; Beißbarth, T. ; Büttner, B. & Hinz, J. et al.​ (2019) 
    Journal of Clinical Medicine, 9(1) pp. 46​.​ DOI: https://doi.org/10.3390/jcm9010046 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​The prognostic capacities of CBP and p300 in locally advanced rectal cancer​
    Rühlmann, F.; Windhof-Jaidhauser, I. M.; Menze, C.; Beißbarth, T. ; Bohnenberger, H.; Ghadimi, M. & Dango, S.​ (2019) 
    World Journal of Surgical Oncology, 17(1) pp. 224​.​ DOI: https://doi.org/10.1186/s12957-019-1764-8 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Combined targeting of HER-2 and HER-3 represents a promising therapeutic strategy in colorectal cancer​
    Conradi, L.-C.; Spitzner, M.; Metzger, A.-L.; Kisly, M.; Middel, P.; Bohnenberger, H. & Gaedcke, J. et al.​ (2019) 
    BMC Cancer, 19(1) pp. 880​.​ DOI: https://doi.org/10.1186/s12885-019-6051-0 
    ​Details  DOI  PMID  PMC 
  • 2019 | Book Chapter
    ​ ​Reconstruction of Different Modes of WNT Dependent Protein Networks from Time Series Protein Quantification​
    Sitte, M.; Menck, K.; Wachter, A.; Reinz, E.; Korf, U.; Wiemann, S.& Bleckmann, A. et al.​ (2019)
    In: Reconstruction of Different Modes of WNT Dependent Protein Networks from Time Series Protein Quantification pp. 175​-180.  DOI: https://doi.org/10.3233/SHTI190823 
    ​Details  DOI  PMID  PMC 
  • 2019 | Book Chapter
    ​ ​Utilizing Molecular Network Information via Graph Convolutional Neural Networks to Predict Metastatic Event in Breast Cancer​
    Chereda, H.; Bleckmann, A.; Kramer, F.; Leha, A.& Beißbarth, T. ​ (2019)
    In: Utilizing Molecular Network Information via Graph Convolutional Neural Networks to Predict Metastatic Event in Breast Cancer pp. 181​-186.  DOI: https://doi.org/10.3233/SHTI190824 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | Erratum
    ​ ​Correction: A comparative study of RNA-Seq and microarray data analysis on the two examples of rectal-cancer patients and Burkitt Lymphoma cells​
    Wolff, A.; Bayerlová, M.; Gaedcke, J.; Kube, D. & Beißbarth, T. ​ (2019) 
    PLoS One, 14(10) art. e0224062​.​ DOI: https://doi.org/10.1371/journal.pone.0224062 
    ​Details  DOI  PMID  PMC 
  • 2019 | Book Chapter
    ​ ​Molecular diagnosis and therapy prediction using biomarkers in the era of next-generation sequencing​
    Perera-Bel, J.  & Beißbarth, T. ​ (2019)
    In:​Duttge, Gunnar; Sax, Ulrich; Schweda, Mark; Umbach, Nadine​ (Eds.), Next-generation medicine : ethische, rechtliche und technologische Fragen genomischer Hochdurchsatzdaten in der klinischen Praxis pp. 11​-19. ​Tübingen: ​Mohr Siebeck.
    ​Details 
  • 2019 | Report
    ​ ​Molekulare Mechanismen in Malignen Lymphomen - Demonstrator der personalisierten Medizin: ​Teil B / WP2, 4, 5, 6 : Schlussbericht : Laufzeit des Vorhabens: 01.03.2015-31.12.2018​
    Beißbarth, T.  & Kube, D. ​ (2019)
    ​Details 
  • 2019 | Book Chapter
    ​ ​Bioinformatic Methods and Resources for Biomarker Discovery, Validation, Development, and Integration​
    Perera-Bel, J.; Leha, A.& Beißbarth, T. ​ (2019)
    In: Predictive Biomarkers in Oncology pp. 149​-164.  DOI: https://doi.org/10.1007/978-3-319-95228-4_11 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​OC-0499 Neutrophilia as prognostic factor for outcome in the CAO/ARO/AIO-04 phase 3 rectal cancer trial​
    Diefenhardt, M.; Hofheinz, R.; Arnold, D.; Müller von den Grün, J.; Liersch, T. ; Ströbel, P.   & Grabenbauer, G. et al.​ (2019) 
    Radiotherapy and Oncology, 133 pp. S256​-S257​.​ DOI: https://doi.org/10.1016/S0167-8140(19)30919-3 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Lack of an Association between the Functional Polymorphism TREM-1 rs2234237 and the Clinical Course of Sepsis among Critically Ill Caucasian Patients-A Monocentric Prospective Genetic Association Study​
    Runzheimer, J.; Mewes, C.; Büttner, B. ; Hinz, J. M. ; Popov, A.-F.; Ghadimi, M. B.   & Kristof, K. et al.​ (2019) 
    Journal of Clinical Medicine, 8(3) art. 301​.​ DOI: https://doi.org/10.3390/jcm8030301 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​CTLA-4 Genetic Variants Predict Survival in Patients with Sepsis​
    Mewes, C.; Büttner, B. ; Hinz, J. M. ; Alpert, A.; Popov, A.-F.; Ghadimi, M. B.   & Beißbarth, T.  et al.​ (2019) 
    Journal of Clinical Medicine, 8(1) art. 70​.​ DOI: https://doi.org/10.3390/jcm8010070 
    ​Details  DOI  PMID  PMC 
  • 2019 | Conference Paper | 
    ​ ​Mapping Cellular Microenvironments: Proximity Labeling and Complexome Profiling​
    Beißbarth, T. ; Bohrer, R.; Feussner, K.; Jahn, O. ; Schmitt, K.; Valerius, O. & Asif, A. R. et al.​ (2019)
    Cells, 8(10) p. 1192. ​Seventh Symposium of the Göttingen Proteomics Forum​, Göttingen.
    MDPI. DOI: https://doi.org/10.3390/cells8101192 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article
    ​ ​Leukocytosis and neutrophilia as independent prognostic immunological biomarkers for clinical outcome in the CAO/ARO/AIO-04 randomized phase 3 rectal cancer trial​
    Diefenhardt, M.; Hofheinz, R.-D.; Martin, D.; Beißbarth, T. ; Arnold, D.; Hartmann, A. & von der Grün, J. et al.​ (2019) 
    International Journal of Cancer, 145(8) pp. 2282​-2291​.​ DOI: https://doi.org/10.1002/ijc.32274 
    ​Details  DOI  PMID  PMC 
  • 2018 | Report
    ​ ​KMU-innovativ-13: Validierung eines cfDNA – basierten diagnostischen Tests zur frühzeitigen Erkennung von Transplantatschädigungen bei Nierentransplantationen: ​Teilprojekt 2 : Schlussbericht (Teilprojekt 2) für das Projekt : Projektlaufzeit: 01.02.2015 bis 31.01.2018 (bis 31.03.2018 nach Verlängerung)​
    Oellerich, M.; Beißbarth, T. ; Friede, T. ; Kramer, F. ; Ellenberger, D.  & Asendorf, T. ​ (2018)
    ​Details 
  • 2018 | Journal Article
    ​ ​FGFR3 mRNA overexpression defines a subset of oligometastatic colorectal cancers with worse prognosis​
    Fromme, J. E.; Schmitz, K.; Wachter, A.; Grzelinski, M.; Zielinski, D.; Koppel, C. & Conradi, L.-C. et al.​ (2018) 
    Oncotarget, 9(63) pp. 32204​-32218​.​ DOI: https://doi.org/10.18632/oncotarget.25941 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFRmut NSCLC in diagnosis, follow-up and treatment​
    Lüke, F.; Blazquez, R.; Yamaci, R. F.; Lu, X.; Pregler, B.; Hannus, S. & Menhart, K. et al.​ (2018) 
    Oncotarget, 9(27) pp. 18844-18857​.​ DOI: https://doi.org/10.18632/oncotarget.24787 
    ​Details  DOI  PMID  PMC 
  • 2018 | Book Chapter
    ​ ​Using RNA-Seq Data for the Detection of a Panel of Clinically Relevant Mutations​
    Wolff, A. ; Perera-Bel, J. ; Schildhaus, H.-U. ; Homayounfar, K. ; Schatlo, B. ; Bleckmann, A.  & Beißbarth, T. ​ (2018)
    In: German Medical Data Sciences: A Learning Healthcare System pp. 217​-221. 
    ​Details 
  • 2018 | Journal Article
    ​ ​The influence of hospital and surgeon volume on survival and local control in rectal cancer: Long-term results of the CAO/ARO/AIO-94 trial.​
    Sprenger, T. ; Beissbarth, T. ; Sauer, R.; Fokas, E.; Hohenberger, W.; Liersch, T.   & Rödel, C. et al.​ (2018) 
    Journal of Clinical Oncology, 36(4, Suppl.) pp. 738​-738​.​ DOI: https://doi.org/10.1200/JCO.2018.36.4_suppl.738 
    ​Details  DOI 
  • 2018 | Conference Proceedings
    ​ ​German medical data sciences: ​a learning healthcare system : proceedings of the 63rd annual meeting of the German Association of Medical Informatics, Biometry and Epidemiology (gmds e.V.) 2018 in Osnabrück, Germany -- GMDS 2018​
    Hübner, U.; Sax, U. ; Prokosch, H.-U.; Breil, B.; Binder, H.; Zapf, A.& Strahwald, B. et al.​ (Eds.) (2018)
    63rd Annual Meeting of the German Association of Medical Informatics, Biometry and Epidemiology​, Osnabrück.
    Amsterdam​: IOS Press.
    ​Details 
  • 2018 | Journal Article | 
    ​ ​Anaemia requiring red blood cell transfusion is associated with unfavourable 90-day survival in surgical patients with sepsis​
    Kristof, K.; Büttner, B. ; Grimm, A.; Mewes, C.; Schmack, B.; Popov, A.-F. & Ghadimi, M. B.  et al.​ (2018) 
    BMC Research Notes, 11(1) art. 879​.​ DOI: https://doi.org/10.1186/s13104-018-3988-z 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Whither systems medicine?​
    Apweiler, R.; Beißbarth, T. ; Berthold, M. R.; Blüthgen, N.; Burmeister, Y.; Dammann, O. & Deutsch, A. et al.​ (2018) 
    Experimental & Molecular Medicine, 50(3) art. e453​.​ DOI: https://doi.org/10.1038/emm.2017.290 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Association of Plane of Total Mesorectal Excision With Prognosis of Rectal Cancer: Secondary Analysis of the CAO/ARO/AIO-04 Phase 3 Randomized Clinical Trial​
    Kitz, J.; Fokas, E.; Beißbarth, T. ; Ströbel, P.; Wittekind, C.; Hartmann, A. & Rüschoff, J. et al.​ (2018) 
    JAMA Surgery, 153(8) art. e181607​.​ DOI: https://doi.org/10.1001/jamasurg.2018.1607 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​The CTLA-4 rs231775 GG genotype is associated with favorable 90-day survival in Caucasian patients with sepsis​
    Mewes, C.; Büttner, B. ; Hinz, J. M. ; Alpert, A.; Popov, A.-F.; Ghadimi, M. B.   & Beißbarth, T.  et al.​ (2018) 
    Scientific Reports, 8(1).​ DOI: https://doi.org/10.1038/s41598-018-33246-9 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper
    ​ ​Integrative omics - from data to biology​
    Dihazi, H.; Asif, A. R; Beißbarth, T. ; Bohrer, R.; Feussner, K.; Feussner, I. & Jahn, O.  et al.​ (2018) 
    Expert Review of Proteomics, 15(6) pp. 463​-466​.​ DOI: https://doi.org/10.1080/14789450.2018.1476143 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Differences in the Reponses to Apheresis Therapy of Patients With 3 Histopathologically Classified Immunopathological Patterns of Multiple Sclerosis​
    Stork, L.; Ellenberger, D. ; Beißbarth, T. ; Friede, T. ; Lucchinetti, C. F.; Brück, W.   & Metz, I. ​ (2018) 
    JAMA Neurology, 75(4) pp. 428​-435​.​ DOI: https://doi.org/10.1001/jamaneurol.2017.4842 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​TGFβ1 regulates HGF-induced cell migration and hepatocyte growth factor receptor MET expression via C-ets-1 and miR-128-3p in basal-like breast cancer​
    Breunig, C.; Erdem, N.; Bott, A.; Greiwe, J. F; Reinz, E.; Bernhardt, S. & Giacomelli, C. et al.​ (2018) 
    Molecular Oncology, 12(9) pp. 1447​-1463​.​ DOI: https://doi.org/10.1002/1878-0261.12355 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Effects of repeated long-term psychosocial stress and acute cannabinoid exposure on mouse corticostriatal circuitries: Implications for neuropsychiatric disorders​
    Tomas-Roig, J.; Piscitelli, F.; Gil, V.; Quintana, E.; Ramió-Torrentà, L. L; Del Río, J. A. & Moore, T. P. et al.​ (2018) 
    CNS Neuroscience & Therapeutics, 24(6) pp. 528​-538​.​ DOI: https://doi.org/10.1111/cns.12810 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​A comparative study of RNA-Seq and microarray data analysis on the two examples of rectal-cancer patients and Burkitt Lymphoma cells.​
    Wolff, A. ; Bayerlová, M. ; Gaedcke, J. ; Kube, D.   & Beißbarth, T. ​ (2018) 
    PLOS ONE, 13(5) art. e0197162​.​ DOI: https://doi.org/10.1371/journal.pone.0197162 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Long-term prognostic impact of surgical complications in the German Rectal Cancer Trial CAO/ARO/AIO-94​
    Sprenger, T.; Beißbarth, T. ; Sauer, R.; Tschmelitsch, J.; Fietkau, R.; Liersch, T. & Hohenberger, W. et al.​ (2018) 
    British Journal of Surgery, 105(11) pp. 1510​-1518​.​ DOI: https://doi.org/10.1002/bjs.10877 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​From somatic variants towards precision oncology: Evidence-driven reporting of treatment options in molecular tumor boards​
    Perera-Bel, J. ; Hutter, B.; Heining, C.; Bleckmann, A. ; Fröhlich, M.; Fröhling, S. & Glimm, H. et al.​ (2018) 
    Genome Medicine, 10(1) pp. 18​.​ DOI: https://doi.org/10.1186/s13073-018-0529-2 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Novel Breast Imaging and Machine Learning: Predicting Breast Lesion Malignancy at Cone-Beam CT Using Machine Learning Techniques​
    Uhlig, J.; Uhlig, A.; Kunze, M.; Fischer, U.; Lotz, J. ; Wienbeck, S.   & Beißbarth, T. ​ (2018) 
    American Journal of Roentgenology, 211(2) pp. W123​-W131​.​ DOI: https://doi.org/10.2214/AJR.17.19298 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​Acute and Long-Term Hemodynamic Effects of MitraClip Implantation on a Preexisting Secondary Right Heart Failure​
    Hünlich, M. ; Lubos, E.; Beuthner, B. E.; Puls, M. ; Bleckmann, A. ; Beißbarth, T.   & Tichelbäcker, T.  et al.​ (2018) 
    BioMed Research International, 2018 art. 7973165​.​ DOI: https://doi.org/10.1155/2018/6817832 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Colorectal cancer susceptibility loci as predictive markers of rectal cancer prognosis after surgery​
    Hu, Y.; Gaedcke, J.; Emons, G.; Beißbarth, T. ; Grade, M.; Jo, P. & Yeager, M. et al.​ (2018) 
    Genes Chromosomes and Cancer, 57(3) pp. 140​-149​.​ DOI: https://doi.org/10.1002/gcc.22512 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​PI3K: A master regulator of brain metastasis-promoting macrophages/microglia​
    Blazquez, R.; Wlochowitz, D.; Wolff, A.; Seitz, S.; Wachter, A.; Perera-Bel, J. & Bleckmann, A. et al.​ (2018) 
    Glia, 66(11) pp. 2438​-2455​.​ DOI: https://doi.org/10.1002/glia.23485 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis​
    Bohnenberger, H.; Kaderali, L.; Ströbel, P.; Yepes, D.; Plessmann, U.; Dharia, N. V & Yao, S. et al.​ (2018) 
    EMBO Molecular Medicine, 10(9).​ DOI: https://doi.org/10.15252/emmm.201708428 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | 
    ​ ​The FER rs4957796 TT genotype is associated with unfavorable 90-day survival in Caucasian patients with severe ARDS due to pneumonia.​
    Hinz, J. M. ; Büttner, B. ; Kriesel, F.; Steinau, M.; Popov, A.-F.; Ghadimi, M. B.   & Beißbarth, T.  et al.​ (2017) 
    Scientific reports, 7(1) art. 9887​.​ DOI: https://doi.org/10.1038/s41598-017-08540-7 
    ​Details  DOI  PMID  PMC 
  • 2017 | Report
    ​ ​Analyse molekularer Marker und Pathways in Krebszellen und deren Microenvironment, welche Schicksal und Lokalisation von Tumormetastasen bestimmen: ​Schlussbericht : Laufzeit des Vorhabens: 01.02.2013-31.12.2016​
    Beißbarth, T. ​ (2017)
    ​Details 
  • 2017 | Journal Article
    ​ ​The Use of Genomic Information In Medical Practice: A Survey on People’s Knowledge, Expectations, And Fears​
    Flatau, L.; Umbach, N.; Sax, U. ; Beißbarth, T. ; Duttge, G.; Schweda, M. & Schulze, T.​ (2017) 
    European Neuropsychopharmacology, 27 art. S369​.​ DOI: https://doi.org/10.1016/j.euroneuro.2016.09.396 
    ​Details  DOI 
  • 2017 | Conference Paper
    ​ ​Proteomic differentiation of pulmonary cancer with squamous cell histology​
    Bohnenberger, H.; Yepes, D.; Merkelbach-Bruse, S.; Emmert, A.; Lois, A.-M.; Yao, S. & Sitte, M. et al.​ (2017)
    ​Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC pp. 4640​-4640. ​Annual Meeting of the American Association for Cancer Research 2017​, Washington, DC. DOI: https://doi.org/10.1158/1538-7445.AM2017-4640 
    ​Details  DOI 
  • 2017 | Journal Article | Research Paper
    ​ ​The utilization of multidiciplinary tumor boards (MDT) in clinical routine: Results of a health care research study focusing on patients with metastatic colorectal cancer​
    Homayounfar, K.; Lowes, M.; Kleiss, M.; Lueck, R.; Detken, S.; Nietert, M.   & Beißbarth, T.  et al.​ (2017) 
    Journal of Clinical Oncology, 35(4, Suppl.) pp. 805​-805​.​ DOI: https://doi.org/10.1200/JCO.2017.35.4_suppl.805 
    ​Details  DOI 
  • 2017 | Conference Paper
    ​ ​Molekulare Konsensus-Subtypisierung für das kolorektale Karzinom in Leber- und Hirnmetastasen​
    Conradi, L.; Wachter, A.; Bayerlova, M.; Schildhaus, H.; Stanek, K.; Ghadimi, M. & Proescholdt, M. et al.​ (2017)
    Zeitschrift für Gastroenterologie, 55(8) pp. e57​-e299. ​Forschungsforum 5: Dünndarm und Dickdarm, Proktologie; Kolonkarzinom – Therapie und Biomarker​, Barcelona. DOI: https://doi.org/10.1055/s-0037-1604858 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​The prognostic impact of surgical complications after combined modality treatment of rectal cancer: Long-term results of the CAO/ARO/AIO-94 trial​
    Sprenger, T. ; Fietkau, R.; Raab, H.-R.; Hohenberger, W.; Liersch, T. ; Rödel, C. & Ghadimi, M.  et al.​ (2017) 
    Journal of Clinical Oncology, 35(4, Suppl.) pp. 670​-670​.​ DOI: https://doi.org/10.1200/JCO.2017.35.4_suppl.670 
    ​Details  DOI 
  • 2017 | Journal Article | Research Paper | 
    ​ ​Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy​
    Jo, P. ; Azizian, A. ; Salendo, J. ; Kramer, F. ; Bernhardt, M. ; Wolff, H. A.   & Gruber, J. et al.​ (2017) 
    International Journal of Molecular Sciences, 18(6) art. 1140​.​ DOI: https://doi.org/10.3390/ijms18061140 
    ​Details  DOI  WoS 
  • 2017 | Journal Article | 
    ​ ​Proteomic profiling of breast cancer metabolism identifies SHMT2 and ASCT2 as prognostic factors​
    Bernhardt, S.; Bayerlová, M. ; Vetter, M.; Wachter, A. ; Mitra, D.; Hanf, V.   & Lantzsch, T. et al.​ (2017) 
    Breast Cancer Research, 19(1) art. 112​.​ DOI: https://doi.org/10.1186/s13058-017-0905-7 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​WNT5A: a motility-promoting factor in Hodgkin lymphoma​
    Linke, F. ; Zaunig, S. ; Nietert, M. M. ; Bonin, F. von ; Lutz, S. ; Dullin, C.   & Janovská, P. et al.​ (2017) 
    Oncogene, 36(1) pp. 13​-23​.​ DOI: https://doi.org/10.1038/onc.2016.183 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | 
    ​ ​The utilization of multidisciplinary tumor boards (MDT) in clinical routine: results of a health care research study focusing on patients with metastasized colorectal cancer​
    Lowes, M.; Kleiss, M.; Lueck, R.; Detken, S.; König, A. O. ; Nietert, M. M.   & Beißbarth, T.  et al.​ (2017) 
    International Journal of Colorectal Disease, 32(10) pp. 1463​-1469​.​ DOI: https://doi.org/10.1007/s00384-017-2871-z 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Biomarkers predict outcome in Charcot-Marie-Tooth disease 1A​
    Fledrich, R.; Mannil, M.; Leha, A.; Ehbrecht, C.; Solari, A.; Pelayo-Negro, A. L & Berciano, J. et al.​ (2017) 
    Journal of Neurology, Neurosurgery & Psychiatry, 88(11) pp. 941​-952​.​ DOI: https://doi.org/10.1136/jnnp-2017-315721 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Relevance of surgery in patients with non-variceal upper gastrointestinal bleeding​
    Dango, S. ; Beißbarth, T. ; Weiss, E. ; Hosseini, A. S. A. ; Raddatz, D. ; Ellenrieder, V.   & Lotz, J.  et al.​ (2017) 
    Langenbeck s Archives of Surgery, 402(3) pp. 509​-519​.​ DOI: https://doi.org/10.1007/s00423-017-1552-2 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​The adaptation of colorectal cancer cells when forming metastases in the liver: expression of associated genes and pathways in a mouse model​
    Bocuk, D. ; Wolff, A. ; Krause, P. ; Salinas, G. ; Bleckmann, A. ; Hackl, C. & Beißbarth, T.  et al.​ (2017) 
    BMC Cancer, 17 pp. 342​.​ DOI: https://doi.org/10.1186/s12885-017-3342-1 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | 
    ​ ​Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia​
    Mohr, S.; Döbele, C. ; Comoglio, F.; Berg, T.; Beck, J.; Bohnenberger, H.   & Alexe, G. et al.​ (2017) 
    Cancer Cell, 31(4) pp. 549​-+​.​ DOI: https://doi.org/10.1016/j.ccell.2017.03.001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​Ror2 Signaling and Its Relevance in Breast Cancer Progression.​
    Bayerlová, M. ; Menck, K. ; Klemm, F. ; Wolff, A. ; Pukrop, T. ; Binder, C.   & Beißbarth, T.  et al.​ (2017) 
    Frontiers in Oncology, 7 art. 135​.​ DOI: https://doi.org/10.3389/fonc.2017.00135 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling​
    Emons, G. ; Spitzner, M. ; Reineke, S. ; Möller, J.; Auslander, N.; Kramer, F.   & Hu, Y. et al.​ (2017) 
    Molecular Cancer Research, 15(11) pp. 1481​-1490​.​ DOI: https://doi.org/10.1158/1541-7786.MCR-17-0205 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Repeated Adjuvant Anti-CEA Radioimmunotherapy After Resection of Colorectal Liver Metastases: Safety, Feasibility, and Long-Term Efficacy Results of a Prospective Phase 2 Study​
    Sahlmann, C.-O. ; Homayounfar, K. ; Niessner, M. ; Dyczkowski, J.; Conradi, L.-C. ; Braulke, F.   & Meller, B.  et al.​ (2017) 
    Cancer, 123(4) pp. 638​-649​.​ DOI: https://doi.org/10.1002/cncr.30390 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Book Chapter
    ​ ​Working with Ontologies​
    Kramer, F.  & Beißbarth, T. ​ (2017)
    In: Working with Ontologies pp. 123​-135.  DOI: https://doi.org/10.1007/978-1-4939-6622-6_6 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | Research Paper
    ​ ​Microenvironmental interactions between endothelial and lymphoma cells: a role for the canonical WNT pathway in Hodgkin lymphoma​
    Linke, F.; Harenberg, M.; Nietert, M. M. ; Zaunig, S.; Bonin, F. von ; Arlt, A.   & Szczepanowski, M. et al.​ (2017) 
    Leukemia, 31(2) pp. 361​-372​.​ DOI: https://doi.org/10.1038/leu.2016.232 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​The Prognostic Value of Tyrosine Kinase SRC Expression in Locally Advanced Rectal Cancer​
    Rühlmann, F. ; Nietert, M. M. ; Sprenger, T. ; Wolff, H. A. ; Homayounfar, K. ; Middel, P. & Bohnenberger, H.  et al.​ (2017) 
    Journal of Cancer, 8(7) pp. 1229​-1237​.​ DOI: https://doi.org/10.7150/jca.16980 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Conference Abstract
    ​ ​Apheresis therapy in multiple sclerosis patients with histopathologically classified immunopathological patterns​
    Stork, L.; Ellenberger, D. ; Beißbarth, T. ; Friede, T. ; Lucchinetti, C.; Brück, W.   & Metz, I. ​ (2016)
    Multiple Sclerosis Journal, 22 , London, ENGLAND.
    London​: Sage Publications Ltd.
    ​Details  WoS 
  • 2016 | Conference Paper
    ​ ​A validatable data management solution for multi-center research consortia: research data management with openBIS​
    Knopp, C.; Bauer, C. R. K. D. ; Baum, B. ; Löhnhardt, B.; Nietert, M. M. ; Beißbarth, T.   & Sax, U. ​ (2016)
    ​Conference: HEC 2016 - Health-Exploring Complexity: An Interdisciplinairy Systems Approach​, München.
    ​Details 
  • 2016 | Journal Article
    ​ ​Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling By Suppression of Mir-146a in Acute Myeloid Leukemia​
    Mohr, S.; Doebele, C.; Berg, T.; Comoglio, F.; Beck, J.; Alexe, G. & Corso, J. et al.​ (2016) 
    Blood, 128(22) pp. 1533​-1533​.​ DOI: https://doi.org/10.1182/blood.V128.22.1533.1533 
    ​Details  DOI 
  • 2016 | Conference Abstract
    ​ ​Repeated anti-CEA radioimmunotherapy (RIT) with 131I-Labetuzumab after complete resection of colorectal liver metastases - safety, feasibility and long-term efficacy results of a prospective phase-II-study​
    Homayounfar, K. ; Sahlmann, C.-O. ; Niessner, M. ; Dyczkowski, J.; Conradi, L.-C. ; Braulke, F.   & Meller, B.  et al.​ (2016)
    Oncology Research and Treatment, 39 
    Basel​: Karger.
    ​Details  WoS 
  • 2016 | Conference Abstract
    ​ ​Neoadjuvant therapy in rectal cancer - challenges of biobanking tumor biopsies taken prior to treatment​
    Jo, P. ; Gusky, L.; Nietert, M. M. ; Kitz, J. ; Conradi, L.-C. ; Müller-Dornieden, A. & Schueler, P. et al.​ (2016)
    Oncology Research and Treatment, 39 
    Basel​: Karger.
    ​Details  WoS 
  • 2016 | Journal Article | 
    ​ ​Decoding Cellular Dynamics in Epidermal Growth Factor Signaling Using a New Pathway-Based Integration Approach for Proteomics and Transcriptomics Data​
    Wachter, A.   & Beißbarth, T. ​ (2016) 
    FRONTIERS IN GENETICS, 6 art. 351​.​ DOI: https://doi.org/10.3389/fgene.2015.00351 
    ​Details  DOI  WoS 
  • 2016 | Book Chapter
    ​ ​Reconstruction of Protein Networks Using Reverse-Phase Protein Array Data​
    von der Heyde, S.; Sonntag, J.; Kramer, F.; Bender, C.; Korf, U.& Beißbarth, T. ​ (2016)
    In: Statistical Analysis in Proteomics pp. 227​-246.  DOI: https://doi.org/10.1007/978-1-4939-3106-4_15 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article
    ​ ​Stage-Dependent Frequency of Lymph Node Metastases in Patients With Rectal Carcinoma After Preoperative Chemoradiation: Results from the CAO/ARO/AIO-94 Trial and From a Comparative Prospective Evaluation With Extensive Pathological Workup​
    Sprenger, T. ; Rothe, H.; Conradi, L.-C. ; Beissbarth, T. ; Kauffels, A. ; Kitz, J.   & Homayounfar, K.  et al.​ (2016) 
    Diseases of the Colon & Rectum, 59(5) pp. 377​-385​.​ DOI: https://doi.org/10.1097/DCR.0000000000000570 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​A simulation framework for correlated count data of features subsets in high-throughput sequencing or proteomics experiments​
    Kruppa, J.; Kramer, F. ; Beißbarth, T.   & Jung, K. ​ (2016) 
    Statistical Applications in Genetics and Molecular Biology, 15(5) pp. 401​-414​.​ DOI: https://doi.org/10.1515/sagmb-2015-0082 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies​
    Jo, P. ; Nietert, M. M. ; Gusky, L.; Kitz, J. ; Conradi, L.-C. ; Müller-Dornieden, A. & Schueler, P. et al.​ (2016) 
    Scientific Reports, 6 art. 35589​.​ DOI: https://doi.org/10.1038/srep35589 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​The putative oncogene CEP72 inhibits the mitotic function of BRCA1 and induces chromosomal instability​
    Lueddecke, S.; Ertych, N. ; Stenzinger, A.; Weichert, W.; Beißbarth, T. ; Dyczkowski, J. & Gaedcke, J.  et al.​ (2016) 
    Oncogene, 35(18) pp. 2398​-2406​.​ DOI: https://doi.org/10.1038/onc.2015.290 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Lymph nodemetastases in ypT1/2 rectal cancer after neoadjuvant chemoradiotherapy. The Achilles heel of organ-preserving operative procedures?​
    Sprenger, T. ; Rothe, H.; Beißbarth, T. ; Conradi, L.-C. ; Kauffels, A. ; Homayounfar, K.   & Behnes, C.-L.  et al.​ (2016) 
    Der Chirurg, 87(7) pp. 593​-601​.​ DOI: https://doi.org/10.1007/s00104-016-0170-9 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Social defeat leads to changes in the endocannabinoid system: An overexpression of calreticulin and motor impairment in mice​
    Tomas-Roig, J.; Piscitelli, F.; Gil, V.; del Río, J. A.; Moore, T. P.; Agbemenyah, H. Y.   & Salinas-Riester, G.  et al.​ (2016) 
    Behavioural Brain Research, 303 pp. 34​-43​.​ DOI: https://doi.org/10.1016/j.bbr.2016.01.036 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​beta-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases​
    Bleckmann, A. ; Conradi, L.-C. ; Menck, K. ; Schmick, N. A.; Schubert, A.; Rietkoetter, E. & Arackal, J. et al.​ (2016) 
    Clinical & Experimental Metastasis, 33(4) pp. 309​-323​.​ DOI: https://doi.org/10.1007/s10585-016-9780-3 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Computational Identification of Key Regulators in Two Different Colorectal Cancer Cell Lines​
    Wlochowitz, D.; Haubrock, M. ; Arackal, J.; Bleckmann, A. ; Wolff, A. ; Beißbarth, T.   & Wingender, E.  et al.​ (2016) 
    Frontiers in Genetics, 7 art. 42​.​ DOI: https://doi.org/10.3389/fgene.2016.00042 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Prognostic value of CXCL12 and CXCR4 in inoperable head and neck squamous cell carcinoma​
    Rave-Fränk, M. ; Tehrany, N.; Kitz, J. ; Leu, M.; Weber, H. E.; Burfeind, P.   & Schliephake, H.  et al.​ (2016) 
    Strahlentherapie und Onkologie, 192(1) pp. 47​-54​.​ DOI: https://doi.org/10.1007/s00066-015-0892-5 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis​
    Metz, I. ; Beißbarth, T. ; Ellenberger, D. ; Pache, F.; Stork, L.; Ringelstein, M. & Aktas, O. et al.​ (2016) 
    Neurology: Neuroimmunology & Neuroinflammation, 3(2) art. e204​.​ DOI: https://doi.org/10.1212/NXI.0000000000000204 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​Analysis of Reverse Phase Protein Array Data: From Experimental Design towards Targeted Biomarker Discovery​
    Wachter, A.; Bernhardt, S.; Beißbarth, T.   & Korf, U.​ (2015) 
    Microarrays, 4(4) pp. 520​-539​.​ DOI: https://doi.org/10.3390/microarrays4040520 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair.​
    Srinivas, U. S.; Dyczkowski, J.; Beißbarth, T. ; Gaedcke, J. ; Mansour, W. Y.; Borgmann, K. & Dobbelstein, M. ​ (2015) 
    Oncotarget, 6(14) pp. 12574​-12586​.​ DOI: https://doi.org/10.18632/oncotarget.3728 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article
    ​ ​Elucidation of B cell receptor signaling in Burkitt’s lymphoma reveals novel signaling nodes with potential therapeutic relevance​
    Oellerich, T.; Corso, J.; Beck, J.; Doebele, C.; Wachter, A.; Lenz, C. & Bohnenberger, H. et al.​ (2015) 
    Clinical Lymphoma, Myeloma & Leukemia, 15 pp. S226​-S227​.​ DOI: https://doi.org/10.1016/j.clml.2015.04.106 
    ​Details  DOI 
  • 2015 | Conference Paper
    ​ ​Automated characterization of cell tracks and classification by using their position coordinates and velocity components​
    Islam, S.; Nietert, M. M. ; Haberl, M.; Friede, T.   & Beißbarth, T. ​ (2015)
    ​Computational Models in Biology and Medicine​, Leipzig.
    ​Details 
  • 2015 | Journal Article
    ​ ​HER-2 as a potential target for rectal cancer treatment: Positivity rate in patients of the CAO/ARO/AIO-94 and -04 trial​
    Conradi, L.-C.; Storch, M.; Nagelmeier, I.; Styczen, H.; Wolff, H. A.; Gaedcke, J. & Sprenger, T. et al.​ (2015) 
    Journal of Clinical Oncology, 33(3, Suppl.) pp. 585​-585​.​ DOI: https://doi.org/10.1200/jco.2015.33.3_suppl.585 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​Expression of genes and pathways associated with colorectal liver metastases in an orthotopic and syngeneic mouse model​
    Bocuk, D.; Wolff, A.; König, S.; Beißbarth, T.   & Krause, P.​ (2015) 
    Zeitschrift für Gastroenterologie, 53(12).​ DOI: https://doi.org/10.1055/s-0035-1568067 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​Mouse models of colorectal and mammary cancer liver metastases and microenvironmental interplay with tumor-associated macrophages (TAMs)​
    Bocuk, D.; Krause, P.; Niebert, S.; Pukrop, T.; Beißbarth, T. ; Ghadimi, M. & Koenig, S.​ (2015) 
    Zeitschrift für Gastroenterologie, 53(1).​ DOI: https://doi.org/10.1055/s-0034-1397186 
    ​Details  DOI 
  • 2015 | Conference Abstract
    ​ ​THE B CELL RECEPTOR SIGNALING OUTPUT IN BURKITT'S LYMPHOMA IS GENOTYPE-SPECIFIC AND IMPACTS SENSITIVITY TOWARDS BCR SIGNALING INHIBITORS​
    Oellerich, T.; Corso, J.; Beck, J.; Pan, K.-T.; Döbele, C. ; Wachter, A.   & Lenz, C.  et al.​ (2015)
    Haematologica, 100 , Vienna, AUSTRIA.
    Pavia​: Ferrata Storti Foundation.
    ​Details  WoS 
  • 2015 | Conference Abstract
    ​ ​Elucidation of B cell receptor signaling in Burkitt's lymphoma reveals novel signaling nodes with potential therapeutic relevance​
    Oellerich, T.; Corso, J.; Beck, J.; Döbele, C. ; Wachter, A. ; Lenz, C.   & Bohnenberger, H.  et al.​ (2015)
    Clinical Lymphoma Myeloma & Leukemia, 15 pp. S226​-S227. 
    Dallas​: Cig Media Group, Lp.
    ​Details  WoS 
  • 2015 | Conference Abstract
    ​ ​Heterogeneity of colorectal cancer liver metastasis - analysis of WNT pathway patterns via High-throughput and bioinformatics profiling​
    Bleckmann, A. ; Wachter, A. ; Conradi, L.-C. ; Wolff, A. ; Hoppenau, C.; Korf, U. & Schildhaus, H.-U.  et al.​ (2015)
    Oncology Research and Treatment, 38 
    Basel​: Karger.
    ​Details  WoS 
  • 2015 | Journal Article
    ​ ​HER-2 and HER-3 expression in liver metastases of patients with colorectal cancer​
    Styczen, H.; Nagelmeier, I.; Beißbarth, T. ; Nietert, M. M. ; Homayounfar, K. ; Sprenger, T.   & Boczek, U. et al.​ (2015) 
    Oncotarget, 6(17) pp. 15065​-15076​.​
    ​Details  PMID  PMC  WoS 
  • 2015 | Conference Abstract
    ​ ​Elucidation of B cell receptor signaling in Burkitt's lymphoma reveals novel signaling nodes with potential therapeutic relevance​
    Döbele, C. ; Corso, J.; Cremer, A.; Muench, S.; Beck, J.; Lenz, C.   & Bohnenberger, H.  et al.​ (2015)
    Cancer Research, 75 , Philadelphia, PA.
    Philadelphia​: Amer Assoc Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2015-50 
    ​Details  DOI  WoS 
  • 2015 | Journal Article
    ​ ​pwOmics: an R package for pathway-based integration of time-series omics data using public database knowledge​
    Wachter, A.   & Beißbarth, T. ​ (2015) 
    Bioinformatics, 31(18) pp. 3072​-3074​.​ DOI: https://doi.org/10.1093/bioinformatics/btv323 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair​
    Wu, Y.; Lee, S.-H.; Williamson, E. A.; Reinert, B. L.; Cho, J. H.; Xia, F. & Jaiswal, A. S. et al.​ (2015) 
    PLoS Genetics, 11(12) art. e1005675​.​ DOI: https://doi.org/10.1371/journal.pgen.1005675 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Genetic Polymorphisms in Endothelin-1 as Predictors for Long-Term Survival and the Cardiac Index in Patients Undergoing On-Pump Cardiac Surgery​
    Mansur, A. ; Steinau, M.; Popov, A.-F.; Milenovic, S.; Bireta, C. ; Weymann, A. & Schotola, H. et al.​ (2015) 
    PLoS ONE, 10(6) art. e0131155​.​ DOI: https://doi.org/10.1371/journal.pone.0131155 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Primary bacteraemia is associated with a higher mortality risk compared with pulmonary and intra-abdominal infections in patients with sepsis: a prospective observational cohort study​
    Mansur, A. ; Klee, Y.; Popov, A.-F.; Erlenwein, J. ; Ghadimi, M. B. ; Beißbarth, T.   & Bauer, M.  et al.​ (2015) 
    BMJ Open, 5(1) art. e006616​.​ DOI: https://doi.org/10.1136/bmjopen-2014-006616 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Comparative study on gene set and pathway topology-based enrichment methods​
    Bayerlová, M. ; Jung, K. ; Kramer, F. ; Klemm, F. ; Bleckmann, A.   & Beißbarth, T. ​ (2015) 
    BMC Bioinformatics, 16 art. 334​.​ DOI: https://doi.org/10.1186/s12859-015-0751-5 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Integrated miRNA and mRNA profiling of tumor-educated macrophages identifies prognostic subgroups in estrogen receptor-positive breast cancer​
    Bleckmann, A. ; Leha, A. ; Artrnann, S.; Menck, K. ; Salinas-Riester, G. ; Binder, C.   & Pukrop, T.  et al.​ (2015) 
    Molecular Oncology, 9(1) pp. 155​-166​.​ DOI: https://doi.org/10.1016/j.molonc.2014.07.023 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​mRNA Profiling Reveals Determinants of Trastuzumab Efficiency in HER2-Positive Breast Cancer​
    Heyde, S. von der ; Wagner, S.; Czerny, A.; Nietert, M. M. ; Ludewig, F. ; Salinas-Riester, G.   & Arlt, D. et al.​ (2015) 
    PLoS ONE, 10(2) art. UNSP e0117818​.​ DOI: https://doi.org/10.1371/journal.pone.0117818 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​The CD14 rs2569190 TT Genotype Is Associated with an Improved 30-Day Survival in Patients with Sepsis: A Prospective Observational Cohort Study​
    Mansur, A. ; Liese, B.; Steinau, M.; Ghadimi, M. B. ; Bergmann, I. ; Tzvetkov, M. V.   & Popov, A.-F. et al.​ (2015) 
    PLoS ONE, 10(5) art. e0127761​.​ DOI: https://doi.org/10.1371/journal.pone.0127761 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​MicroRNA-101 Suppresses Tumor Cell Proliferation by Acting as an Endogenous Proteasome Inhibitor via Targeting the Proteasome Assembly Factor POMP​
    Zhang, X.; Schulz, R.; Edmunds, S. ; Krueger, E.; Markert, E.; Gaedcke, J.   & Cormet-Boyaka, E. et al.​ (2015) 
    Molecular Cell, 59(2) pp. 243​-257​.​ DOI: https://doi.org/10.1016/j.molcel.2015.05.036 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Chronic kidney disease is associated with a higher 90-day mortality than other chronic medical conditions in patients with sepsis​
    Mansur, A. ; Mulwande, E.; Steinau, M.; Bergmann, I. ; Popov, A.-F.; Ghadimi, M. B.   & Beißbarth, T.  et al.​ (2015) 
    Scientific Reports, 5 art. 10539​.​ DOI: https://doi.org/10.1038/srep10539 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Automated 3D-2D registration of X-ray microcomputed tomography with histological sections for dental implants in bone using chamfer matching and simulated annealing​
    Becker, K.; Stauber, M.; Schwarz, F. & Beißbarth, T. ​ (2015) 
    Computerized Medical Imaging and Graphics, 44 pp. 62​-68​.​ DOI: https://doi.org/10.1016/j.compmedimag.2015.04.005 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Impact of statin therapy on mortality in patients with sepsis-associated acute respiratory distress syndrome (ARDS) depends on ARDS severity: a prospective observational cohort study​
    Mansur, A. ; Steinau, M.; Popov, A.-F.; Ghadimi, M. B. ; Beißbarth, T. ; Bauer, M.   & Hinz, J. M. ​ (2015) 
    BMC Medicine, 13 art. 128​.​ DOI: https://doi.org/10.1186/s12916-015-0368-6 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​A global microRNA screen identifies regulators of the ErbB receptor signaling network​
    Bischoff, A.; Bayerlová, M. ; Strotbek, M.; Schmid, S.; Beißbarth, T.   & Olayioye, M. A.​ (2015) 
    Cell Communication and Signaling, 13(5) art. 5​.​ DOI: https://doi.org/10.1186/s12964-015-0084-z 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​High-grade acute organ toxicity and p16(INK4A) expression as positive prognostic factors in primary radio(chemo)therapy for patients with head and neck squamous cell carcinoma​
    Tehrany, N.; Kitz, J. ; Rave-Fränk, M. ; Lorenzen, S.; Li, L. I.; Küffer, S.   & Hess, C. F.  et al.​ (2015) 
    Strahlentherapie und Onkologie, 191(7) pp. 566​-572​.​ DOI: https://doi.org/10.1007/s00066-014-0801-3 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Newly Constructed Network Models of Different WNT Signaling Cascades Applied to Breast Cancer Expression Data​
    Bayerlová, M. ; Klemm, F. ; Kramer, F. ; Pukrop, T. ; Beißbarth, T.   & Bleckmann, A. ​ (2015) 
    PLoS ONE, 10(12) art. e0144014​.​ DOI: https://doi.org/10.1371/journal.pone.0144014 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Perioperative Blood Glucose Levels < 150 mg/dL are Associated With Improved 5-Year Survival in Patients Undergoing On-Pump Cardiac Surgery A Prospective, Observational Cohort Study​
    Mansur, A. ; Popov, A.-F.; Ameen, A. H.; Bergmann, I. ; Brandes, I. F. ; Beißbarth, T.   & Bauer, M.  et al.​ (2015) 
    Medicine, 94(45) art. e2035​.​ DOI: https://doi.org/10.1097/MD.0000000000002035 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Preoperative Prediction of Lymph Node Status by Circulating Mir-18b and Mir-20a During Chemoradiotherapy in Patients with Rectal Cancer​
    Azizian, A. ; Kramer, F. ; Jo, P. ; Wolff, H. A. ; Beißbarth, T. ; Skarupke, R. & Bernhardt, M.  et al.​ (2015) 
    World Journal of Surgery, 39(9) pp. 2329​-2335​.​ DOI: https://doi.org/10.1007/s00268-015-3083-8 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Conference Paper
    ​ ​Abstract 247: A functional genomics and a systems biology approach identify POMP as a potential therapeutic target for colorectal cancer​
    Camps, J.; Hummon, A. H.; Emons, G.; Kramer, F.; Pitt, J. J.; Grade, M. & Nguyen, Q. T. et al.​ (2014)
    pp. 247​-247. ​Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC​
    American Association for Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM10-247 
    ​Details  DOI 
  • 2014 | Journal Article
    ​ ​HER2 and HER3 expression in hepatic metastases of colorectal cancer: New targets for specific treatment approaches?​
    Conradi, L.-C.; Styczen, H.; Sprenger, T.; Wolff, H. A.; Middel, P.; Nagelmeier, I. & Rüschoff, J. et al.​ (2014) 
    Journal of Clinical Oncology, 32(3_suppl) pp. 567​-567​.​
    ​Details  WoS 
  • 2014 | Conference Paper
    ​ ​Abstract 5640: KRAS and BRAF in rectal cancer treated with preoperative chemoradiotherapy​
    Gaedcke, J.; Grade, M.; Jung, K.; Wolff, H. A.; Beissbarth, T. ; Becker, H. & Ried, T. et al.​ (2014)
    pp. 5640​-5640. ​Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC​
    American Association for Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM10-5640 
    ​Details  DOI 
  • 2014 | Journal Article
    ​ ​Residual rectal cancer after preoperative radiochemotherapy (ypT1-2): An indication for local excision instead of radical surgery?​
    Sprenger, T.; Rothe, H.; Conradi, L.-C.; Homayounfar, K.; Beissbarth, T. ; Ghadimi, B. M. & Liersch, T.​ (2014) 
    Journal of Clinical Oncology, 32(3_suppl) pp. 546​-546​.​ DOI: https://doi.org/10.1200/jco.2014.32.3_suppl.546 
    ​Details  DOI 
  • 2014 | Conference Abstract
    ​ ​The prognostic role of tumor regression grading after preoperative chemoradiotherapy for locally advanced rectal carcinoma revisited: 11-year median follow-up results of the CAO/ARO/AIO-94 trial​
    Fokas, E.; Liersch, T. ; Fietkau, R.; Hohenberger, W.; Beißbarth, T. ; Hess, C. & Becker, H. et al.​ (2014)
    Strahlentherapie und Onkologie, 190 ​20th Annual Congress of the German-Society-for-Radiation-Oncology​, Dusseldorf, GERMANY.
    Munich​: Urban & Vogel.
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Effects of 5-FU dose monitoring under neoadjuvant radiochemotherapy for locally advanced rectal cancer​
    Quack, H.; Stanek, K.; Wolff, H. A. ; Dröge, L. H.; Binder, L.; Bleckmann, A.   & Nietert, M. M.  et al.​ (2014)
    Oncology Research and Treatment, 37 
    Basel​: Karger.
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​SRC expression in locally advanced rectal cancer-before and after neoadjuvant chemoradiotherapy​
    Ruehlmann, F. ; Nietert, M. M. ; Sprenger, T. ; Wolff, H. A. ; Homayounfar, K. ; Ghadimi, M. B.   & Beißbarth, T.  et al.​ (2014)
    Oncology Research and Treatment, 37 
    Basel​: Karger.
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​TNF-alpha stimulation enhances ROS-dependent cell migration via NF-kappa B activation in liver cells​
    Kastl, L.; Sven, S.; Beißbarth, T. ; Becker, C.-M.; Krammer, P. H. & Guelow, K.​ (2014)
    Free Radical Biology and Medicine, 75 
    New york​: Elsevier Science Inc. DOI: https://doi.org/10.1016/j.freeradbiomed.2014.10.765 
    ​Details  DOI  WoS 
  • 2014 | Conference Abstract
    ​ ​Residual rectal cancer after preoperative radiochemotherapy (ypT1-2): An indication for local excision instead of radical surgery?​
    Sprenger, T. ; Rothe, H.; Conradi, L.-C. ; Homayounfar, K. ; Beißbarth, T. ; Ghadimi, M. B.   & Liersch, T. ​ (2014)
    Journal of Clinical Oncology, 32(3) ​Gastrointestinal Cancers Symposium​, San Francisco, CA.
    Alexandria​: Amer Soc Clinical Oncology.
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Targeting STAT3 in vitro and in vivo reveals a novel therapeutic strategy to sensitize colorectal cancer cells to chemoradiotherapy​
    Spitzner, M. ; Roesler, B.; Bielfeld, C.; Herzberg, C.; Emons, G. ; Gaedcke, J.   & Rave-Fränk, M.  et al.​ (2014)
    Cancer Research, 74(19) ​105th Annual Meeting of the American-Association-for-Cancer-Research (AACR)​, San Diego, CA.
    Philadelphia​: Amer Assoc Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2014-855 
    ​Details  DOI  WoS 
  • 2014 | Conference Abstract
    ​ ​Cytokinesis-block micronucleus cytome assay for in vivo and in vitro lymphocyte radiosensitivity in patients undergoing radiochemotherapy for locally advanced rectal cancer​
    Dröge, L. H.; Hennies, S.; Beißbarth, T. ; Lorenzen, S.; Conradi, L.-C. ; Quack, H. & Ghadimi, M. B.  et al.​ (2014)
    Strahlentherapie und Onkologie, 190 ​20th Annual Congress of the German-Society-for-Radiation-Oncology​, Dusseldorf, GERMANY.
    Munich​: Urban & Vogel.
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Targeting STAT3 as a therapeutic strategy to sensitize colorectal cancer to chemoradiotherapy​
    Grade, M. ; Spitzner, M. ; Roesler, B.; Bielfeld, C.; Gaedcke, J. ; Wolff, H. A.   & Beißbarth, T.  et al.​ (2014)
    Oncology Research and Treatment, 37 
    Basel​: Karger.
    ​Details  WoS 
  • 2014 | Conference Abstract
    ​ ​Wnt/beta-catenin signaling mediates resistance of colorectal cancer cells to chemoradiotherapy​
    Emons, G. ; Spitzner, M. ; Reineke, S. ; Möller, J.; Kendziorra, E.; Beißbarth, T.   & Rave-Fränk, M.  et al.​ (2014)
    Cancer Research, 74(19) , San Diego, CA.
    Philadelphia​: Amer Assoc Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2014-3946 
    ​Details  DOI  WoS 
  • 2014 | Journal Article | 
    ​ ​Reverse phase protein array based tumor profiling identifies a biomarker signature for risk classification of hormone receptor-positive breast cancer​
    Sonntag, J.; Bender, C.; Soons, Z.; Heyde, S. von der ; König, R.; Wiemann, S. & Sinn, H.-P. et al.​ (2014) 
    Translational Proteomics, 2 pp. 52​-59​.​ DOI: https://doi.org/10.1016/j.trprot.2014.02.001 
    ​Details  DOI 
  • 2014 | Journal Article | 
    ​ ​Boolean ErbB network reconstructions and perturbation simulations reveal individual drug response in different breast cancer cell lines​
    Heyde, S. von der ; Bender, C.; Henjes, F.; Sonntag, J.; Korf, U. & Beißbarth, T. ​ (2014) 
    BMC Systems Biology, 8 art. 75​.​ DOI: https://doi.org/10.1186/1752-0509-8-75 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​R-based software for the integration of pathway data into bioinformatic algorithms.​
    Kramer, F. ; Bayerlová, M.   & Beißbarth, T. ​ (2014) 
    Biology, 3(1) pp. 85​-100​.​ DOI: https://doi.org/10.3390/biology3010085 
    ​Details  DOI  PMID  PMC 
  • 2014 | Journal Article
    ​ ​Superior vena cava syndrome caused by a malignant tumor: a retrospective single-center analysis of 124 cases​
    Høhloch, K. ; Bertram, N.; Trümper, L. H. ; Beißbarth, T.   & Griesinger, F.​ (2014) 
    Journal of Cancer Research and Clinical Oncology, 140(12) pp. 2129​-2134​.​ DOI: https://doi.org/10.1007/s00432-014-1764-6 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​Impact of frailty on short- and long-term morbidity and mortality after transcatheter aortic valve implantation: risk assessment by Katz Index of activities of daily living​
    Puls, M. ; Sobisiak, B.; Bleckmann, A. ; Jacobshagen, C. ; Danner, B. C. ; Huenlich, M.   & Beißbarth, T.  et al.​ (2014) 
    EuroIntervention, 10(5) pp. 609​-619​.​ DOI: https://doi.org/10.4244/EIJY14M08_03 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo​
    Spitzner, M. ; Roesler, B.; Bielfeld, C.; Emons, G. ; Gaedcke, J. ; Wolff, H. A.   & Rave-Fränk, M.  et al.​ (2014) 
    International Journal of Cancer, 134(4) pp. 997​-1007​.​ DOI: https://doi.org/10.1002/ijc.28429 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Adaption of the global test idea to proteomics data with missing values​
    Jung, K. ; Dihazi, H. ; Bibi, A.; Dihazi, G. H.   & Beißbarth, T. ​ (2014) 
    Bioinformatics, 30(10) pp. 1424​-1430​.​ DOI: https://doi.org/10.1093/bioinformatics/btu062 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Tumor Regression Grading After Preoperative Chemoradiotherapy for Locally Advanced Rectal Carcinoma Revisited: Updated Results of the CAO/ARO/AIO-94 Trial​
    Fokas, E.; Liersch, T. ; Fietkau, R.; Hohenberger, W.; Beißbarth, T. ; Hess, C. F.   & Becker, H. et al.​ (2014) 
    Journal of Clinical Oncology, 32(15) pp. 1554​-1562​.​ DOI: https://doi.org/10.1200/JCO.2013.54.3769 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Selected items from the Charcot-Marie-Tooth (CMT) Neuropathy Score and secondary clinical outcome measures serve as sensitive clinical markers of disease severity in CMT1A patients​
    Mannil, M. ; Solari, A.; Leha, A. ; Pelayo-Negro, A. L.; Berciano, J.; Schlotter-Weigel, B. & Walter, M. C. et al.​ (2014) 
    Neuromuscular Disorders, 24(11) pp. 1003​-1017​.​ DOI: https://doi.org/10.1016/j.nmd.2014.06.431 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​Identification of a DNA methylation signature to predict disease-free survival in locally advanced rectal cancer​
    Gaedcke, J.; Leha, A.; Claus, R.; Weichenhan, D.; Jung, K.; Kitz, J. & Grade, M. et al.​ (2014) 
    Oncotarget, 5(18) pp. 8123​-8135​.​ DOI: https://doi.org/10.18632/oncotarget.2347 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Wnt/beta-catenin signaling integrates patterning and metabolism of the insect growth zone​
    Oberhofer, G.; Grossmann, D.; Siemanowski, J. L.; Beißbarth, T.   & Bucher, G. ​ (2014) 
    Development, 141(24) pp. 4740​-4750​.​ DOI: https://doi.org/10.1242/dev.112797 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​Dynamics of mRNA and polysomal abundance in early 3T3-L1 adipogenesis​
    Heyde, S. von der ; Fromm-Dornieden, C.; Salinas-Riester, G. ; Beißbarth, T.   & Baumgartner, B. G.​ (2014) 
    BMC Genomics, 15 art. 381​.​ DOI: https://doi.org/10.1186/1471-2164-15-381 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​TNF-alpha mediates mitochondrial uncoupling and enhances ROS-dependent cell migration via NF-kappa B activation in liver cells​
    Kastl, L.; Sauer, S. W.; Ruppert, T.; Beißbarth, T. ; Becker, M. S.; Suess, D. & Krammer, P. H. et al.​ (2014) 
    FEBS Letters, 588(1) pp. 175​-183​.​ DOI: https://doi.org/10.1016/j.febslet.2013.11.033 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​Failure of acute procedural success predicts adverse outcome after percutaneous edge-to-edge mitral valve repair with MitraClip​
    Puls, M. ; Tichelbäcker, T. ; Bleckmann, A. ; Huenlich, M. ; von der Ehe, K.; Beuthner, B. E. & Rueter, K. et al.​ (2014) 
    EuroIntervention, 9(12) pp. 1407​-1417​.​ DOI: https://doi.org/10.4244/EIJV9I12A238 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​RPPanalyzer Toolbox: An improved R package for analysis of reverse phase protein array data​
    Heyde, S. von der ; Sonntag, J.; Kaschek, D.; Bender, C.; Bues, J.; Wachter, A.   & Timmer, J. et al.​ (2014) 
    BioTechniques, 57(3) pp. 125​-135​.​ DOI: https://doi.org/10.2144/000114205 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib​
    Landmann, H.; Proia, D. A.; He, S.; Ogden, F. L.; Kramer, F.-J. ; Beißbarth, T.   & Grade, M.  et al.​ (2014) 
    Cell Death and Disease, 5 art. e1411​.​ DOI: https://doi.org/10.1038/cddis.2014.378 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​The regulatory toll-like receptor 4 genetic polymorphism rs11536889 is associated with renal, coagulation and hepatic organ failure in sepsis patients​
    Mansur, A. ; von Gruben, L.; Popov, A.-F.; Steinau, M.; Bergmann, I. ; Ross, D. & Ghadimi, M. B.  et al.​ (2014) 
    Journal of Translational Medicine, 12 art. 177​.​ DOI: https://doi.org/10.1186/1479-5876-12-177 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Ninety-Day Survival Rate of Patients With Sepsis Relates to Programmed Cell Death 1 Genetic Polymorphism rs11568821​
    Mansur, A.; Hinz, J.; Hillebrecht, B.; Bergmann, I.; Popov, A. F.; Ghadimi, M. & Bauer, M. et al.​ (2014) 
    Journal of Investigative Medicine, 62(3) pp. 638​-643​.​ DOI: https://doi.org/10.2310/JIM.0000000000000059 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Association of CD133 expression levels with the k-ras mutation status in rectal cancers before and after preoperative radiochemotherapy.​
    Sprenger, T.; Gaedcke, J.; Conradi, L.-C.; Jo, P.; Jung, K.; Beissbarth, T.   & Homayounfar, K. et al.​ (2013) 
    Journal of Clinical Oncology, 31(4_suppl) pp. 400​-400​.​ DOI: https://doi.org/10.1200/jco.2013.31.4_suppl.400 
    ​Details  DOI 
  • 2013 | Conference Proceedings
    ​ ​German Conference on Bioinformatics 2013​
    Beißbarth, T. ; Kollmar, M. ; Leha, A. ; Morgenstern, B. ; Schultz, A.-K.; Waack, S.  & Wingender, E. ​ (Eds.) (2013)
    German Conference on Bioinformatics 2013​, Göttingen.
    ​Details 
  • 2013 | Journal Article
    ​ ​Klinische Bedeutung unterschiedlicher KRAS-Mutationen im Rektumkarzinom​
    Jo, P.; Jung, K.; Kaulfuß, S.; Salendo, J.; Beißbarth, T. ; Spitzner, M. & Wolff, H. et al.​ (2013) 
    Zeitschrift für Gastroenterologie, 51(8).​ DOI: https://doi.org/10.1055/s-0033-1353032 
    ​Details  DOI 
  • 2013 | Conference Paper
    ​ ​Utilization of ordinal response structures in classification with high-dimensional expression data​
    Leha, A. ; Jung, K.   & Beißbarth, T. ​ (2013)
    ​German Conference on Bioinformatics 2013 pp. 9​-100. , Dagstuhl. DOI: https://doi.org/10.4230/OASIcs.GCB.2013.90 
    ​Details  DOI 
  • 2013 | Report
    ​ ​Identifizierung neuer therapeutischer Strategien für Brustkrebs durch datengetriebene Modellierung der Tumorprogression: ​Abschlussbericht des BreastSys-Verbunds ; Laufzeit des Vorhabens: 01.02.2009 - 31.01.2013​
    Beißbarth, T. ​ (2013)
    ​Details 
  • 2013 | Journal Article
    ​ ​Deciphering The Molecular Impact Of Myc Overexpression On B Cell Receptor Signaling and Its Implications For Burkitt Lymphoma Treatment​
    Oellerich, T.; Corso, J.; Lemeer, S.; Schütz, E.; Beck, J.; Lorenzen, S. & Beißbarth, T.  et al.​ (2013) 
    Blood, 122(21) pp. 3018​-3018​.​ DOI: https://doi.org/10.1182/blood.V122.21.3018.3018 
    ​Details  DOI 
  • 2013 | Conference Paper
    ​ ​Targeting STAT3in vitroandin vivoreveals a novel therapeutic strategy to sensitize colorectal cancer cells to chemoradiotherapy​
    Spitzner, M.; Roesler, B.; Bielfeld, C.; Herzberg, C.; Emons, G.; Gaedcke, J. & Rave-Fränk, M. et al.​ (2013)
    Cancer Research, 73(8, Suppl.) pp. 68​-68. ​104th Annual Meeting of the American-Association-for-Cancer-Research (AACR)​, Washington, DC. DOI: https://doi.org/10.1158/1538-7445.AM2013-68 
    ​Details  DOI 
  • 2013 | Journal Article
    ​ ​Lymph Node Metastases in Rectal Cancer After Preoperative Radiochemotherapy Impact of Intramesorectal Distribution and Residual Micrometastatic Involvement​
    Sprenger, T. ; Rothe, H.; Becker, H.; Beißbarth, T. ; Homayounfar, K. ; Gauss, K. & Kitz, J.  et al.​ (2013) 
    American Journal of Surgical Pathology, 37(8) pp. 1283​-1289​.​
    ​Details  PMID  PMC  WoS 
  • 2013 | Conference Abstract
    ​ ​Protein biomarker signature for risk classification of hormone receptor positive breast cancer identified by reverse phase protein array based tumor profiling​
    Sonntag, J.; Bender, C.; Aulmann, S.; Heyde, S. von der ; Burwinkel, B.; Wiemann, S. & Beißbarth, T.  et al.​ (2013)
    European Journal of Cancer, 49 ​European Cancer Congress 2013 - 17th ECCO / 38th ESMO / 32nd ESTRO​, Amsterdam, NETHERLANDS.
    Oxford​: Elsevier Sci Ltd.
    ​Details  WoS 
  • 2013 | Conference Abstract
    ​ ​Identification of prognostic miRNAs in breast cancer through profiling of tumor educated macrophages​
    Bleckmann, A. ; Leha, A. ; Artmann, S.; Menck, K. ; Binder, C. ; Pukrop, T.   & Beißbarth, T.  et al.​ (2013)
    Onkologie, 36 
    Basel​: Karger.
    ​Details  WoS 
  • 2013 | Conference Abstract
    ​ ​HER-2 and HER-3 expression in locally advanced rectal cancer and metachronous metastases: new targets for treatment approaches?​
    Conradi, L.-C. ; Styczen, H.; Sprenger, T. ; Wolff, H. A. ; Middel, P.; Nagelmeier, I. & Rüschoff, J. R.  et al.​ (2013)
    Onkologie, 36 
    Basel​: Karger.
    ​Details  WoS 
  • 2013 | Conference Abstract
    ​ ​5-FU dose monitoring under neoadjuvant radiochemotherapy and adjuvant chemotherapy for locally advanced rectal cancer​
    Conradi, L.-C. ; Quack, H.; Sprenger, T. ; Wolff, H. A. ; Binder, L.; Ghadimi, M. B.   & Homayounfar, K.  et al.​ (2013)
    Onkologie, 36 
    Basel​: Karger.
    ​Details  WoS 
  • 2013 | Conference Abstract
    ​ ​Gender influences acute Toxicity during Chemoradiotherapy in Patients with Rectal cancer: Long-term results of the CAO/ARO/AIO 94 Trial​
    Wolff, H. A. ; Conradi, L.-C. ; Beißbarth, T. ; Leha, A. ; Hohenberger, W.; Merkel, S. & Fietkau, R. et al.​ (2013)
    Strahlentherapie und Onkologie, 189 ​19th Annual Congress of the German-Society-for-Radiation-Oncology​, Berlin, GERMANY.
    Munich​: Urban & Vogel.
    ​Details  WoS 
  • 2013 | Conference Abstract
    ​ ​Context of persistent DNA Damage (Micronuclei) and Late Side Effects after Multimodal Radiochemotherapy in Patients with locally advanced Rectal cancer​
    Droege, L. H.; Hennies, S.; Beißbarth, T. ; Conradi, L.-C. ; Helms, C.; Hess, C. F.   & Rave-Fränk, M.  et al.​ (2013)
    Strahlentherapie und Onkologie, 189 ​19th Annual Congress of the German-Society-for-Radiation-Oncology​, Berlin, GERMANY.
    Munich​: Urban & Vogel.
    ​Details  WoS 
  • 2013 | Journal Article
    ​ ​Lymph Node Metastases in Rectal Cancer After Preoperative Radiochemotherapy​
    Sprenger, T.; Rothe, H.; Becker, H.; Beissbarth, T. ; Homayounfar, K.; Gauss, K. & Kitz, J. et al.​ (2013) 
    American Journal of Surgical Pathology, 37(8) pp. 1283​-1289​.​ DOI: https://doi.org/10.1097/PAS.0b013e3182886ced 
    ​Details  DOI 
  • 2013 | Conference Abstract
    ​ ​Association of CD133 expression levels with the k-ras mutation status in rectal cancers before and after preoperative radiochemotherapy​
    Sprenger, T. ; Gaedcke, J. ; Conradi, L.-C. ; Jo, P. ; Jung, K. ; Beißbarth, T.   & Homayounfar, K.  et al.​ (2013)
    Journal of Clinical Oncology, 31(4) ​Gastrointestinal Cancers Symposium of the American-Society-of-Clinical-Oncology (ASCO)​, San Francisco, CA.
    Alexandria​: Amer Soc Clinical Oncology.
    ​Details  WoS 
  • 2013 | Journal Article
    ​ ​Enrichment of CD133-expressing cells in rectal cancers treated with preoperative radiochemotherapy is an independent marker for metastasis and survival​
    Sprenger, T. ; Conradi, L.-C. ; Beißbarth, T. ; Ermert, H.; Homayounfar, K. ; Middel, P. & Rüschoff, J. R.  et al.​ (2013) 
    Cancer, 119(1) pp. 26​-35​.​ DOI: https://doi.org/10.1002/cncr.27703 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Estimating Learning Outcomes From Pre- and Posttest Student Self-Assessments: A Longitudinal Study​
    Schiekirka, S.; Reinhardt, D.; Beißbarth, T. ; Anders, S. ; Pukrop, T.   & Raupach, T. ​ (2013) 
    Academic Medicine, 88(3) pp. 369​-375​.​ DOI: https://doi.org/10.1097/ACM.0b013e318280a6f6 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​rBiopaxParser-an R package to parse, modify and visualize BioPAX data​
    Kramer, F. ; Bayerlová, M. ; Klemm, F. ; Bleckmann, A.   & Beißbarth, T. ​ (2013) 
    Bioinformatics, 29(4) pp. 520​-522​.​ DOI: https://doi.org/10.1093/bioinformatics/bts710 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Inactivation of Patched1 in Mice Leads to Development of Gastrointestinal Stromal-Like Tumors That Express Pdgfr alpha but Not Kit​
    Pelczar, P.; Zibat, A.; van Dop, W. A.; Heijmans, J.; Bleckmann, A. ; Gruber, W. & Nitzki, F. et al.​ (2013) 
    Gastroenterology, 144(1) pp. 134​-U256​.​ DOI: https://doi.org/10.1053/j.gastro.2012.09.061 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/beta-Catenin Pathway in Colorectal Cancer​
    Camps, J.; Pitt, J. J.; Emons, G. ; Hummon, A. B.; Case, C. M.; Grade, M.   & Jones, T. L. et al.​ (2013) 
    Cancer Research, 73(6) pp. 2003​-2013​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-12-3159 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Conference Paper
    ​ ​Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a,-224,-132 and let7g​
    Salendo, J. ; Spitzner, M. ; Kramer, F. ; Zhang, X.; Jo, P. ; Wolff, H. A.   & Kitz, J.  et al.​ (2013)
    Radiotherapy and Oncology, 108(3) pp. 451​-457. ​13th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology​, Ermatingen, SWITZERLAND.
    Clare​: Elsevier Ireland Ltd. DOI: https://doi.org/10.1016/j.radonc.2013.06.032 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | 
    ​ ​Gender affects acute organ toxicity during radiochemotherapy for rectal cancer: Long-term results of the German CAO/ARO/AIO-94 phase III trial​
    Wolff, H. A. ; Conradi, L.-C. ; Beißbarth, T. ; Leha, A. ; Hohenberger, W.; Merkel, S. & Fietkau, R. et al.​ (2013) 
    Radiotherapy and Oncology, 108(1) pp. 48​-54​.​ DOI: https://doi.org/10.1016/j.radonc.2013.05.009 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Frequency of HER-2 Positivity in Rectal Cancer and Prognosis​
    Conradi, L.-C. ; Styczen, H.; Sprenger, T. ; Wolff, H. A. ; Roedel, C.; Nietert, M. M.   & Homayounfar, K.  et al.​ (2013) 
    American Journal of Surgical Pathology, 37(4) pp. 522​-531​.​ DOI: https://doi.org/10.1097/PAS.0b013e318272ff4d 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Preoperative Chemoradiation Therapy With Capecitabine/Oxaliplatin and Cetuximab in Rectal Cancer: Long-Term Results of a Prospective Phase 1/2 Study​
    Fokas, E.; Conradi, L.-C. ; Weiss, C.; Sprenger, T. ; Middel, P.; Rau, T. & Dellas, K. et al.​ (2013) 
    International Journal of Radiation Oncology*Biology*Physics, 87(5) pp. 992​-999​.​ DOI: https://doi.org/10.1016/j.ijrobp.2013.09.011 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | 
    ​ ​Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear beta-catenin in cerebral metastasis of lung adenocarcinomas​
    Bleckmann, A. ; Siam, L.; Klemm, F. ; Rietkoetter, E.; Wegner, C. ; Kramer, F.-J.   & Beißbarth, T.  et al.​ (2013) 
    Clinical & Experimental Metastasis, 30(4) pp. 471​-482​.​ DOI: https://doi.org/10.1007/s10585-012-9552-7 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Connecting high-dimensional mRNA and miRNA expression data for binary medical classification problems​
    Fuchs, M.; Beißbarth, T. ; Wingender, E.   & Jung, K. ​ (2013) 
    Computer Methods and Programs in Biomedicine, 111(3) pp. 592​-601​.​ DOI: https://doi.org/10.1016/j.cmpb.2013.05.013 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​847 Identification of a Biomarker Signature to Predict the Need for Chemotherapy in Patients With Hormone Receptor Positive Breast Cancer​
    Korf, U.; Sonntag, J.; Bender, C.; Wiemann, S.; Aulmann, S.; Sinn, P. & Burwinkel, B. et al.​ (2012) 
    European Journal of Cancer, 48 pp. S203​-S204​.​ DOI: https://doi.org/10.1016/S0959-8049(12)71480-6 
    ​Details  DOI 
  • 2012 | Journal Article
    ​ ​STAT3 is a potential molecular target to sensitize colorectal cancer cells to chemoradiotherapy​
    Grade, M.; Spitzner, M.; Roesler, B.; Bielfeld, C.; Emons, G.; Gaedcke, J. & Rave-Fränk, M. et al.​ (2012) 
    Zeitschrift für Gastroenterologie, 50(8).​ DOI: https://doi.org/10.1055/s-0032-1324029 
    ​Details  DOI 
  • 2012 | Journal Article
    ​ ​Association of the expression of CD133 in locally advanced rectal cancer with tumor regression and survival after neoadjuvant radiochemotherapy​
    Sprenger, T.; Conradi, L.; Beißbarth, T. ; Rüschoff, J.; Ghadimi, B. M.; Rödel, C. & Becker, H. et al.​ (2012) 
    Journal of Clinical Oncology, 30(4, Suppl.) pp. 479​-479​.​ DOI: https://doi.org/10.1200/jco.2012.30.4_suppl.479 
    ​Details  DOI 
  • 2012 | Journal Article
    ​ ​HER2/neu expression in locally advanced rectal cancer cUICC II/III and its correlation with long-term prognosis​
    Conradi, L.-C.; Styczen, H.; Sprenger, T.; Becker, H.; Ghadimi, M. B.; Beißbarth, T.   & Middel, P. et al.​ (2012) 
    Journal of Clinical Oncology, 30(4, Suppl.) pp. 493​-493​.​ DOI: https://doi.org/10.1200/jco.2012.30.4_suppl.493 
    ​Details  DOI 
  • 2012 | Conference Abstract
    ​ ​Identification of new translationally regulated genes in early Adipogenesis​
    Fromm-Dornieden, C.; Heyde, S. von der ; Lytovchenko, O. ; Salinas-Riester, G. ; Brenig, B. B. ; Beißbarth, T.   & Baumgartner, B. G.​ (2012)
    Wiener klinische Wochenschrift, 124(17-18) pp. 660​-661. 
    Wien​: Springer.
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​Preoperative vs. postoperative chemoradiotherapy for locally advanced rectal cancer: Results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years​
    Sauer, R.; Liersch, T. ; Merkel, S.; Fietkau, R.; Hohenberger, W.; Hess, C. F.   & Becker, H. et al.​ (2012)
    Strahlentherapie und Onkologie, 188 ​18th Annual Congress of the German-Society-for-Radiation-Oncology​, Wiesbaden, GERMANY.
    Munich​: Urban & Vogel.
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​Clinical significance and prognostic impact of CD133 expression in rectal cancer treated with preoperative radiochemotherapy​
    Sprenger, T. ; Conradi, L.-C. ; Beißbarth, T. ; Homayounfar, K. ; Rüschoff, J. R. ; Roedel, C. & Ghadimi, M. B.  et al.​ (2012)
    Journal of Clinical Oncology, 30(15) ​48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO)​, Chicago, IL.
    Alexandria​: Amer Soc Clinical Oncology.
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​Analyzing breast-cancer gene expression data using a newly developed graph-based WNT model in breast cancer​
    Bleckmann, A. ; Bayerlova, M. ; Kramer, F.-J. ; Klemm, F. ; Binder, C. ; Pukrop, T.   & Beißbarth, T. ​ (2012)
    Onkologie, 35 
    Basel​: Karger.
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​Cetuximab, capecitabine, oxaliplatin, and radiotherapy as preoperative triple treatment for rectal cancer (CET-CAPOX-RT-Phase-I/II Study): Influence on long-term survival and relevance of biomarkers​
    Liersch, T. ; Conradi, L.-C. ; Sprenger, T. ; Middel, P.; Suelberg, H.; Roedel, F. & Rüschoff, J. R.  et al.​ (2012)
    Journal of Clinical Oncology, 30(15) ​48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO)​, Chicago, IL.
    Alexandria​: Amer Soc Clinical Oncology.
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​HER-2 in locally advanced rectal cancer (cUICC II/III): positivity rate and prognostic value​
    Conradi, L.-C. ; Styczen, H.; Sprenger, T. ; Wolff, H. A. ; Homayounfar, K. ; Becker, H. & Ghadimi, M. B.  et al.​ (2012)
    British Journal of Surgery, 99 ​99th Annual Congress of the Swiss-Society-of-Surgery​, Davos, SWITZERLAND.
    Malden​: Wiley-blackwell.
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​HER2 status in locally advanced rectal cancer and metachronous metastases: Opportunity for a new therapeutic approach?​
    Conradi, L.-C. ; Styczen, H.; Sprenger, T. ; Homayounfar, K. ; Wolff, H. A. ; Bleckmann, A.   & Rüschoff, J. R.  et al.​ (2012)
    Journal of Clinical Oncology, 30(15) , Chicago, IL.
    Alexandria​: Amer Soc Clinical Oncology.
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​Identification of a Biomarker Signature to Predict the Need for Chemotherapy in Patients With Hormone Receptor Positive Breast Cancer​
    Korf, U.; Sonntag, J.; Bender, C.; Wiemann, S.; Aulmann, S.; Sinn, P. & Burwinkel, B. et al.​ (2012)
    European Journal of Cancer, 48 pp. S203​-S204. ​22nd Biennial Congress of the European-Association-for-Cancer-Research​, Barcelona, SPAIN.
    Oxford​: Elsevier Sci Ltd.
    ​Details  WoS 
  • 2012 | Conference Abstract
    ​ ​Stat3 is a potential molecular target for chemoradiosensitization of colorectal cancer cells​
    Spitzner, M. ; Roesler, B.; Bielfeld, C.; Gaedcke, J. ; Rave-Fränk, M. ; Beißbarth, T.   & Ried, T. et al.​ (2012)
    Cancer Research, 72 
    Philadelphia​: Amer Assoc Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2012-3446 
    ​Details  DOI  WoS 
  • 2012 | Conference Abstract
    ​ ​The Wnt transcription factor TCF4 mediates resistance of colorectal cancer cells to (chemo-) radiotherapy in a beta-catenin independent manner​
    Grade, M. ; Eimer, C. ; Emons, G. ; Kendziorra, E.; Spitzner, M. ; Gaedcke, J.   & Wolff, H. A.  et al.​ (2012)
    Cancer Research, 72 
    Philadelphia​: Amer Assoc Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2012-5729 
    ​Details  DOI  WoS 
  • 2012 | Journal Article | 
    ​ ​Implementierung und Erprobung eines Lernziel-basierten Evaluationssystems im Studium der Humanmedizin​
    Raupach, T. ; Schiekirka, S.; Münscher, C.; Beißbarth, T. ; Himmel, W. ; Burckhardt, G. & Pukrop, T. ​ (2012) 
    GMS Zeitschrift für medizinische Ausbildung, 29(3) art. 14​.​
    ​Details 
  • 2012 | Journal Article
    ​ ​CpG island methylator phenotype infers a poor disease-free survival in locally advanced rectal cancer​
    Jo, P. ; Jung, K. ; Grade, M. ; Conradi, L.-C. ; Wolff, H. A. ; Kitz, J.   & Becker, H. et al.​ (2012) 
    Surgery, 151(4) pp. 564​-570​.​ DOI: https://doi.org/10.1016/j.surg.2011.08.013 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | Research Paper | 
    ​ ​Piloting an outcome-based programme evaluation tool in undergraduate medical education​
    Raupach, T.; Schiekirka, S.; Münscher, C.; Beißbarth, T. ; Himmel, W. ; Burckhardt, G. & Pukrop, T.​ (2012) 
    GMS Zeitschrift für medizinische Ausbildung, 29(3) art. Doc44​.​ DOI: https://doi.org/10.3205/zma000814 
    ​Details  DOI  PMID  PMC 
  • 2012 | Journal Article | 
    ​ ​Detection of Simultaneous Group Effects in MicroRNA Expression and Related Target Gene Sets​
    Artmann, S.; Jung, K. ; Bleckmann, A.   & Beißbarth, T. ​ (2012) 
    PLoS ONE, 7(6) art. e38365​.​ DOI: https://doi.org/10.1371/journal.pone.0038365 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | 
    ​ ​Extrinsic and intrinsic regulation of DOR/TP53INP2 expression in mice: effects of dietary fat content, tissue type and sex in adipose and muscle tissues​
    Fromm-Dornieden, C.; Lytovchenko, O. ; Heyde, S. von der ; Behnke, N.; Hogl, S.; Berghoff, J. & Koepper, F. et al.​ (2012) 
    Nutrition & Metabolism, 9 art. 86​.​ DOI: https://doi.org/10.1186/1743-7075-9-86 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​The Histone H2B Monoubiquitination Regulatory Pathway Is Required for Differentiation of Multipotent Stem Cells​
    Karpiuk, O.; Najafova, Z. ; Kramer, F. ; Hennion, M. ; Galonska, C.; Koenig, A. & Snaidero, N. et al.​ (2012) 
    Molecular Cell, 46(5) pp. 705​-713​.​ DOI: https://doi.org/10.1016/j.molcel.2012.05.022 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​German medical students lack knowledge of how to treat smoking and problem drinking​
    Strobel, L.; Schneider, N. K.; Krampe, H. ; Beißbarth, T. ; Pukrop, T. ; Anders, S.   & West, R. et al.​ (2012) 
    Addiction, 107(10) pp. 1878​-1882​.​ DOI: https://doi.org/10.1111/j.1360-0443.2012.03907.x 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | 
    ​ ​Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs​
    Henjes, F.; Bender, C.; Heyde, S. von der ; Braun, L.; Mannsperger, H. A.; Schmidt, C. & Wiemann, S. et al.​ (2012) 
    Oncogenesis, 1 art. UNSP e16​.​ DOI: https://doi.org/10.1038/oncsis.2012.16 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​Preoperative Versus Postoperative Chemoradiotherapy for Locally Advanced Rectal Cancer: Results of the German CAO/ARO/AIO-94 Randomized Phase III Trial After a Median Follow-Up of 11 Years​
    Sauer, R.; Liersch, T. ; Merkel, S.; Fietkau, R.; Hohenberger, W.; Hess, C. F.   & Becker, H. et al.​ (2012) 
    Journal of Clinical Oncology, 30(16) pp. 1926​-1933​.​ DOI: https://doi.org/10.1200/JCO.2011.40.1836 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | 
    ​ ​Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells​
    Hummon, A. B.; Pitt, J. J.; Camps, J.; Emons, G. ; Skube, S. B.; Huppi, K. & Jones, T. L. et al.​ (2012) 
    Molecular Cancer, 11 art. 1​.​ DOI: https://doi.org/10.1186/1476-4598-11-1 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | 
    ​ ​Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells​
    Fromm-Dornieden, C.; Heyde, S. von der ; Lytovchenko, O. ; Salinas-Riester, G. ; Brenig, B. B. ; Beißbarth, T.   & Baumgartner, B. G.​ (2012) 
    BMC Molecular Biology, 13 art. 9​.​ DOI: https://doi.org/10.1186/1471-2199-13-9 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | 
    ​ ​Cohesin is required for expression of the estrogen receptor-alpha (ESR1) gene​
    Prenzel, T.; Kramer, F. ; Bedi, U.; Nagarajan, S. ; Beißbarth, T.   & Johnsen, S. A. ​ (2012) 
    Epigenetics & Chromatin, 5 art. 13​.​ DOI: https://doi.org/10.1186/1756-8935-5-13 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | 
    ​ ​Bilobar spreading of colorectal liver metastases does not significantly affect survival after R0 resection in the era of interdisciplinary multimodal treatment​
    Homayounfar, K. ; Bleckmann, A. ; Conradi, L.-C. ; Sprenger, T.; Beißbarth, T. ; Lorf, T.   & Niessner, M.  et al.​ (2012) 
    International Journal of Colorectal Disease, 27(10) pp. 1359​-1367​.​ DOI: https://doi.org/10.1007/s00384-012-1455-1 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | Letter Note | 
    ​ ​A new analysis approach of epidermal growth factor receptor pathway activation patterns provides insights into cetuximab resistance mechanisms in head and neck cancer​
    Heyde, S. von der   & Beißbarth, T. ​ (2012) 
    BMC Medicine, 10 art. 43​.​ DOI: https://doi.org/10.1186/1741-7015-10-43 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | 
    ​ ​Effects of pulmonary acid aspiration on the lungs and extra-pulmonary organs: a randomized study in pigs​
    Heuer, J. F.; Sauter, P. A.; Pelosi, P.; Herrmann, P. ; Brück, W. ; Perske, C.   & Schoendube, F. et al.​ (2012) 
    CRITICAL CARE, 16(2) art. R35​.​ DOI: https://doi.org/10.1186/cc11214 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​The Rectal Cancer microRNAome - microRNA Expression in Rectal Cancer and Matched Normal Mucosa​
    Gaedcke, J. ; Grade, M. ; Camps, J.; Sokilde, R.; Kaczkowski, B.; Schetter, A. J. & Difilippantonio, M. J. et al.​ (2012) 
    Clinical Cancer Research, 18(18) pp. 4919​-4930​.​ DOI: https://doi.org/10.1158/1078-0432.CCR-12-0016 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | 
    ​ ​Effects of High-frequency Oscillatory Ventilation on Systemic and Cerebral Hemodynamics and Tissue Oxygenation: An Experimental Study in Pigs​
    Heuer, J. F.; Sauter, P. A.; Barwing, J.; Herrmann, P. ; Crozier, T. A.; Bleckmann, A.   & Beißbarth, T.  et al.​ (2012) 
    Neurocritical Care, 17(2) pp. 281​-292​.​ DOI: https://doi.org/10.1007/s12028-011-9566-z 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​Acute Toxicity of Radiochemotherapy in Rectal Cancer Patients: A Risk Particularly for Carriers of the TGFB1 Pro25 variant​
    Schirmer, M. A. ; Mergler, C. P. N.; Rave-Fränk, M. ; Herrmann, M. K. A.; Hennies, S.; Gaedcke, J.   & Conradi, L.-C.  et al.​ (2012) 
    International Journal of Radiation Oncology*Biology*Physics, 83(1) pp. 149​-157​.​ DOI: https://doi.org/10.1016/j.ijrobp.2011.05.063 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Spatiotemporal regulation of multiple overlapping sense and novel natural antisense transcripts at the Nrgn and Camk2n1 gene loci during mouse cerebral corticogenesis​
    Ling, K.-H.; Hewitt, C. A; Beißbarth, T. ; Hyde, L.; Cheah, P.-S.; Smyth, G. K & Tan, S.-S. et al.​ (2011) 
    Cerebral Cortex, 21(3) pp. 683​-697​.​ DOI: https://doi.org/10.1093/cercor/bhq141 
    ​Details  DOI  PMID  PMC 
  • 2011 | Journal Article
    ​ ​6126 POSTER Thymidylate Synthase as Biomarker in Rectal Cancer Patients After 5-FU-based Radiochemotherapy – Evaluation of the Prognostic Capacity in Pre-treatment Biopsies and Resected Adenocarcinoma​
    Conradi, L.; Bleckmann, A.; Sprenger, T.; Schirmer, M.; Homayounfar, K.; Wolff, H. & Becker, H. et al.​ (2011) 
    European Journal of Cancer, 47 pp. S430​.​ DOI: https://doi.org/10.1016/S0959-8049(11)71771-3 
    ​Details  DOI 
  • 2011 | Journal Article
    ​ ​6130 POSTER Survivin Expression in Rectal Cancer During Preoperative Radiochemotherapy and Its Impact on Metastasis and Patients' Survival​
    Sprenger, T.; Rödel, F.; Beissbarth, T. ; Conradi, L.; Yildirim, M.; Ghadimi, B. & Becker, H. et al.​ (2011) 
    European Journal of Cancer, 47 pp. S431​.​ DOI: https://doi.org/10.1016/S0959-8049(11)71775-0 
    ​Details  DOI 
  • 2011 | Journal Article
    ​ ​Biomarker study in rectal cancer patients after 5FU-based radiochemotherapy: Evaluation of the prognostic capacity of thymidylate synthase in pretreatment biopsies and resected adenocarcinoma.​
    Conradi, L.; Bleckmann, A.; Schirmer, M.; Sprenger, T.; Homayounfar, K.; Wolff, H. A. & Becker, H. et al.​ (2011) 
    Journal of Clinical Oncology, 29(4_suppl) pp. 435​-435​.​ DOI: https://doi.org/10.1200/jco.2011.29.4_suppl.435 
    ​Details  DOI 
  • 2011 | Journal Article
    ​ ​Association of survivin expression following neoadjuvant radiochemotherapy in rectal cancer with distant metastases and survival.​
    Sprenger, T.; Rödel, F.; Beissbarth, T. ; Conradi, L.; Homayounfar, K.; Ghadimi, B. M. & Yildrim, M. et al.​ (2011) 
    Journal of Clinical Oncology, 29(4_suppl) pp. 483​-483​.​ DOI: https://doi.org/10.1200/jco.2011.29.4_suppl.483 
    ​Details  DOI 
  • 2011 | Report
    ​ ​The Emacs Org-mode: Reproducible Research and Beyond​
    Leha, A.  & Beißbarth, T. ​ (2011)
    ​Details 
  • 2011 | Conference Abstract
    ​ ​Management of early Adipogenesis through Translational Control​
    Fromm-Dornieden, C.; Lytovchenko, O. ; Salinas-Riester, G. ; Heyde, S. von der ; Beißbarth, T. ; Brenig, B. B.   & Baumgartner, B. G.​ (2011)
    Wiener klinische Wochenschrift, 123 
    Wien​: Springer.
    ​Details  WoS 
  • 2011 | Conference Abstract
    ​ ​Silencing of TCF7L2 sensitizes Wnt/beta-catenin signaling-dependent colorectal cancer cells to radiation​
    Kendziorra, E.; Ahlborn, K.; Spitzner, M. ; Rave-Fränk, M. ; Gaedcke, J. ; Emons, G.   & Kramer, F.  et al.​ (2011)
    Cancer Research, 71 
    Philadelphia​: Amer Assoc Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2011-2490 
    ​Details  DOI  WoS 
  • 2011 | Conference Abstract
    ​ ​Identification of potential relevant pathways and genes for resistance to chemoradiotherapy in colorectal cancer cells​
    Grade, M. ; Spitzner, M. ; Emons, G. ; Kramer, F. ; Gaedcke, J. ; Rave-Fränk, M.   & Scharf, J.-G. et al.​ (2011)
    Cancer Research, 71 
    Philadelphia​: Amer Assoc Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2011-2508 
    ​Details  DOI  WoS 
  • 2011 | Conference Abstract
    ​ ​Thymidylate Synthase as Biomarker in Rectal Cancer Patients After 5-FU-based Radiochemotherapy - Evaluation of the Prognostic Capacity in Pre-treatment Biopsies and Resected Adenocarcinoma​
    Conradi, L.-C. ; Bleckmann, A. ; Sprenger, T. ; Schirmer, M. A. ; Homayounfar, K. ; Wolff, H. A.   & Becker, H. et al.​ (2011)
    European Journal of Cancer, 47 ​European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care​, Stockholm, SWEDEN.
    Oxford​: Elsevier Sci Ltd.
    ​Details  WoS 
  • 2011 | Conference Abstract
    ​ ​Biomarker study in rectal cancer patients after 5FU-based radiochemotherapy: Evaluation of the prognostic capacity of thymidylate synthase in pretreatment biopsies and resected adenocarcinoma.​
    Conradi, L.-C. ; Bleckmann, A. ; Schirmer, M. A. ; Sprenger, T. ; Homayounfar, K. ; Wolff, H. A.   & Becker, H. et al.​ (2011)
    Journal of Clinical Oncology, 29(4) 
    Alexandria​: Amer Soc Clinical Oncology.
    ​Details  PMID  PMC  WoS 
  • 2011 | Conference Abstract
    ​ ​Association of survivin expression following neoadjuvant radiochemotherapy in rectal cancer with distant metastases and survival.​
    Sprenger, T. ; Roedel, F.; Beißbarth, T. ; Conradi, L.-C. ; Homayounfar, K. ; Ghadimi, M. B.   & Yildrim, M. et al.​ (2011)
    Journal of Clinical Oncology, 29(4) 
    Alexandria​: Amer Soc Clinical Oncology.
    ​Details  PMID  PMC  WoS 
  • 2011 | Conference Abstract
    ​ ​Survivin Expression in Rectal Cancer During Preoperative Radiochemotherapy and Its Impact on Metastasis and Patients' Survival​
    Sprenger, T. ; Roedel, F.; Beißbarth, T. ; Conradi, L.-C. ; Yildirim, M.; Ghadimi, M. B.   & Becker, H. et al.​ (2011)
    European Journal of Cancer, 47 ​European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care​, Stockholm, SWEDEN.
    Oxford​: Elsevier Sci Ltd.
    ​Details  WoS 
  • 2011 | Conference Abstract
    ​ ​TGFB1 Pro25 allele as a risk marker for higher-grade acute Organ toxicity (CTC >= Grad2) during neoadjuvant Chemoradiotherapy in patients with locally advanced Rectal cancer (UICC Stage II/III)​
    Christiansen, H.; Schirmer, M. A. ; Mergler, C. P. N.; Rave-Fränk, M. ; Hennies, S.; Gaedcke, J.   & Conradi, L.-C.  et al.​ (2011)
    Strahlentherapie und Onkologie, 187 , Wiesbaden, GERMANY.
    Munich​: Urban & Vogel.
    ​Details  WoS 
  • 2011 | Conference Abstract
    ​ ​A lack of down-regulation of survivin after neoadjuvant Chemoradiotherapy for Rectal cancer with distant metastasis and Reduced survival rate linked​
    Roedel, F.; Sprenger, T. ; Beißbarth, T. ; Conradi, L.-C. ; Rothe, H.; Homayonfaur, K. & Wolff, H. A.  et al.​ (2011)
    Strahlentherapie und Onkologie, 187 ​17th Annual Meeting of the German-Society-for-Radiation-Oncology​, Wiesbaden, GERMANY.
    Munich​: Urban & Vogel.
    ​Details  WoS 
  • 2011 | Journal Article | 
    ​ ​Graph based fusion of miRNA and mRNA expression data improves clinical outcome prediction in prostate cancer​
    Gade, S.; Porzelius, C.; Faelth, M.; Brase, J. C.; Wuttig, D.; Kuner, R. & Binder, H. et al.​ (2011) 
    BMC Bioinformatics, 12 art. 488​.​ DOI: https://doi.org/10.1186/1471-2105-12-488 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Estrogen-Dependent Gene Transcription in Human Breast Cancer Cells Relies upon Proteasome-Dependent Monoubiquitination of Histone H2B​
    Prenzel, T.; Begus-Nahrmann, Y.; Kramer, F. ; Hennion, M. ; Hsu, C.; Gorsler, T. & Hintermair, C. et al.​ (2011) 
    Cancer Research, 71(17) pp. 5739​-5753​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-11-1896 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Leveraging external knowledge on molecular interactions in classification methods for risk prediction of patients​
    Porzelius, C.; Johannes, M.; Binder, H. & Beißbarth, T. ​ (2011) 
    Biometrical Journal, 53(2) pp. 190​-201​.​ DOI: https://doi.org/10.1002/bimj.201000155 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​Reporting FDR analogous confidence intervals for the log fold change of differentially expressed genes​
    Jung, K. ; Friede, T.   & Beißbarth, T. ​ (2011) 
    BMC Bioinformatics, 12 art. 288​.​ DOI: https://doi.org/10.1186/1471-2105-12-288 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​Failure of Downregulation of Survivin Following Neoadjuvant Radiochemotherapy in Rectal Cancer Is Associated with Distant Metastases and Shortened Survival​
    Sprenger, T. ; Roedel, F.; Beißbarth, T. ; Conradi, L.-C. ; Rothe, H.; Homayounfar, K.   & Wolff, H. A.  et al.​ (2011) 
    Clinical Cancer Research, 17(6) pp. 1623​-1631​.​ DOI: https://doi.org/10.1158/1078-0432.CCR-10-2592 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Comparison of global tests for functional gene sets in two-group designs and selection of potentially effect-causing genes​
    Jung, K. ; Becker, B.; Brunner, E.   & Beißbarth, T. ​ (2011) 
    Bioinformatics, 27(10) pp. 1377​-1383​.​ DOI: https://doi.org/10.1093/bioinformatics/btr152 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Towards outcome-based programme evaluation: Using student comparative self-assessments to determine teaching effectiveness​
    Raupach, T. ; Muenscher, C.; Beißbarth, T. ; Burckhardt, G. & Pukrop, T. ​ (2011) 
    Medical Teacher, 33(8) pp. E446​-E453​.​ DOI: https://doi.org/10.3109/0142159X.2011.586751 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​beta-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis​
    Klemm, F. ; Bleckmann, A. ; Siam, L.; Chuang, H.-N.; Rietkoetter, E.; Behme, D.   & Schulz, M. et al.​ (2011) 
    Carcinogenesis, 32(3) pp. 434​-442​.​ DOI: https://doi.org/10.1093/carcin/bgq269 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​Sequential interim analyses of survival data in DNA microarray experiments​
    Leha, A. ; Beißbarth, T.   & Jung, K. ​ (2011) 
    BMC Bioinformatics, 12 art. 127​.​ DOI: https://doi.org/10.1186/1471-2105-12-127 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​TMPRSS2-ERG- specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-beta signaling​
    Brase, J. C.; Johannes, M.; Mannsperger, H. A.; Faelth, M.; Metzger, J.; Kacprzyk, L. A. & Andrasiuk, T. et al.​ (2011) 
    BMC Cancer, 11 art. 507​.​ DOI: https://doi.org/10.1186/1471-2407-11-507 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy​
    Kendziorra, E.; Ahlborn, K.; Spitzner, M. ; Rave-Fränk, M. ; Emons, G. ; Gaedcke, J.   & Kramer, F.  et al.​ (2011) 
    Carcinogenesis, 32(12) pp. 1824​-1831​.​ DOI: https://doi.org/10.1093/carcin/bgr222 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​Thymidylate Synthase as a Prognostic Biomarker for Locally Advanced Rectal Cancer after multimodal Treatment​
    Conradi, L.-C. ; Bleckmann, A. ; Schirmer, M. A. ; Sprenger, T. ; Jo, P. ; Homayounfar, K.   & Wolff, H. A.  et al.​ (2011) 
    Annals of Surgical Oncology, 18(9) pp. 2442​-2452​.​ DOI: https://doi.org/10.1245/s10434-011-1608-4 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​pathClass: an R-package for integration of pathway knowledge into support vector machines for biomarker discovery​
    Johannes, M.; Froehlich, H.; Sueltmann, H. & Beißbarth, T. ​ (2011) 
    Bioinformatics, 27(10) pp. 1442​-1443​.​ DOI: https://doi.org/10.1093/bioinformatics/btr157 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | 
    ​ ​Inferring signalling networks from longitudinal data using sampling based approaches in the R-package 'ddepn'​
    Bender, C.; vd Heyde, S.; Henjes, F.; Wiemann, S.; Korf, U. & Beißbarth, T. ​ (2011) 
    BMC Bioinformatics, 12 art. 291​.​ DOI: https://doi.org/10.1186/1471-2105-12-291 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Gender-Specific Acute Organ Toxicity during Intensified Preoperative Radiochemotherapy for Rectal Cancer​
    Wolff, H. A. ; Conradi, L.-C. ; Schirmer, M. A. ; Beißbarth, T. ; Sprenger, T. ; Rave-Fränk, M.   & Hennies, S. et al.​ (2011) 
    The Oncologist, 16(5) pp. 621​-631​.​ DOI: https://doi.org/10.1634/theoncologist.2010-0414 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Circulating miRNAs are correlated with tumor progression in prostate cancer​
    Brase, J. C.; Johannes, M.; Schlomm, T.; Faelth, M.; Haese, A.; Steuber, T. & Beißbarth, T.  et al.​ (2011) 
    International Journal of Cancer, 128(3) pp. 608​-616​.​ DOI: https://doi.org/10.1002/ijc.25376 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets​
    Grade, M. ; Hummon, A. B.; Camps, J.; Emons, G. ; Spitzner, M. ; Gaedcke, J.   & Hoermann, P. et al.​ (2011) 
    International Journal of Cancer, 128(5) pp. 1069​-1079​.​ DOI: https://doi.org/10.1002/ijc.25453 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease​
    Tye-Din, J. A; Stewart, J. A; Dromey, J. A; Beißbarth, T. ; van Heel, D. A; Tatham, A. & Henderson, K. et al.​ (2010) 
    Science Translational Medicine, 2(41) pp. 41ra51​-41ra51​.​ DOI: https://doi.org/10.1126/scitranslmed.3001012 
    ​Details  DOI  PMID  PMC 
  • 2010 | Journal Article
    ​ ​A serial analysis of gene expression profile of the Alzheimer's disease Tg2576 mouse model​
    George, A. J; Gordon, L.; Beißbarth, T. ; Koukoulas, I.; Holsinger, R M D.; Perreau, V. & Cappai, R. et al.​ (2010) 
    Neurotoxicity Research, 17(4) pp. 360​-379​.​ DOI: https://doi.org/10.1007/s12640-009-9112-3 
    ​Details  DOI  PMID  PMC 
  • 2010 | Journal Article
    ​ ​SAGE analysis of genes differentially expressed in presymptomatic TgSOD1G93A transgenic mice identified cellular processes involved in early stage of ALS pathology​
    Guipponi, M.; Li, Q.-X.; Hyde, L.; Beißbarth, T. ; Smyth, G. K; Masters, C. L & Scott, H. S​ (2010) 
    Journal of Molecular Neuroscience, 41(1) pp. 172​-182​.​ DOI: https://doi.org/10.1007/s12031-009-9317-1 
    ​Details  DOI  PMID  PMC 
  • 2010 | Conference Abstract
    ​ ​Survivin: A potential predictive and prognostic marker in multimodal rectal cancer therapy.​
    Sprenger, T.; Rodel, F.; Rothe, H.; Beissbarth, T. ; Conradi, L.; Ghadimi, B. M. & Becker, H. et al.​ (2010)
    Journal of Clinical Oncology, 28(15_suppl) pp. e14115​-e14115. 
    Alexandria​: Amer Soc Clinical Oncology. DOI: https://doi.org/10.1200/jco.2010.28.15_suppl.e14115 
    ​Details  DOI  WoS 
  • 2010 | Conference Abstract
    ​ ​A COMBINED FUNCTIONAL AND SYSTEMS BIOLOGY APPROACH IDENTIFIES COLORECTAL CANCER GENES AS NOVEL POTENTIAL THERAPEUTIC TARGETS​
    Grade, M. ; Hummon, A. B.; Camps, J.; Emons, G.; Spitzner, M. ; Gaedcke, J.   & Hoermann, P. et al.​ (2010)
    Cellular Oncology, 32(3) pp. 164​-165. ​Congress of the International-Society-for-Cellular-Oncology​, Dresden, GERMANY.
    Amsterdam​: Ios Press.
    ​Details  WoS 
  • 2010 | Conference Abstract
    ​ ​The effect of KRAS mutations on the rectal cancer transcriptome: clinical implications​
    Gaedcke, J. ; Grade, M. ; Jung, K. ; Camps, J.; Jo, P. ; Becker, H. & Beißbarth, T.  et al.​ (2010)
    EJC SUPPLEMENTS, 8(7) ​22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics​, Berlin, GERMANY.
    Oxford​: Pergamon-elsevier Science Ltd. DOI: https://doi.org/10.1016/S1359-6349(10)71892-9 
    ​Details  DOI  WoS 
  • 2010 | Conference Abstract
    ​ ​RNAi-MEDIATED SILENCING OF TCF7L2 SENSITIZES COLORECTAL CANCER CELLS TO RADIATION​
    Kendziorra, E.; Spitzner, M. ; Emons, G.; Ahlborn, K.; Gaedcke, J. ; Rave-Fränk, M.   & Beißbarth, T.  et al.​ (2010)
    Cellular Oncology, 32(3) pp. 229​-230. ​Congress of the International-Society-for-Cellular-Oncology​, Dresden, GERMANY.
    Amsterdam​: Ios Press.
    ​Details  WoS 
  • 2010 | Conference Abstract
    ​ ​Detection and molecular characterization of circulating tumour cells in blood of breast cancer patients​
    Wagner, S.; Schneeweiss, A.; Wiemann, S.; Beißbarth, T.   & Arlt, D.​ (2010)
    Onkologie, 33 
    Basel​: Karger.
    ​Details  WoS 
  • 2010 | Conference Abstract
    ​ ​Quantitative analysis of ERBB signal transduction networks in breast cancer cell lines​
    Korf, U.; Henjes, F.; Mannsperger, H. A.; Schmidt, C.; Bender, C.; Joeker, A. & Wiemann, S. et al.​ (2010)
    Onkologie, 33 
    Basel​: Karger.
    ​Details  WoS 
  • 2010 | Journal Article
    ​ ​Integration of pathway knowledge into a reweighted recursive feature elimination approach for risk stratification of cancer patients​
    Johannes, M.; Brase, J. C.; Froehlich, H.; Gade, S.; Gehrmann, M.; Faelth, M. & Sueltmann, H. et al.​ (2010) 
    Bioinformatics, 26(17) pp. 2136​-2144​.​ DOI: https://doi.org/10.1093/bioinformatics/btq345 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​Preoperative Chemoradiotherapy Does Not Necessarily Reduce Lymph Node Retrieval in Rectal Cancer Specimens-Results from a Prospective Evaluation with Extensive Pathological Work-up​
    Sprenger, T. ; Rothe, H.; Homayounfar, K. ; Beißbarth, T. ; Ghadimi, M. B. ; Becker, H. & Liersch, T. ​ (2010) 
    Journal of Gastrointestinal Surgery, 14(1) pp. 96​-103​.​ DOI: https://doi.org/10.1007/s11605-009-1057-6 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​Impact of RNA degradation on gene expression profiling​
    Opitz, L. ; Salinas-Riester, G. ; Grade, M. ; Jung, K. ; Jo, P. ; Emons, G.   & Ghadimi, M. B.  et al.​ (2010) 
    BMC Medical Genomics, 3 art. 36​.​ DOI: https://doi.org/10.1186/1755-8794-3-36 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​A new sensitivity-preferred strategy to build prediction rules for therapy response of cancer patients using gene expression data​
    Jung, K. ; Grade, M. ; Gaedcke, J. ; Jo, P. ; Opitz, L. ; Becker, H. & Ghadimi, M. B.  et al.​ (2010) 
    Computer Methods and Programs in Biomedicine, 100(2) pp. 132​-139​.​ DOI: https://doi.org/10.1016/j.cmpb.2010.03.016 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​QuantProReloaded: quantitative analysis of microspot immunoassays​
    Joecker, A.; Sonntag, J.; Henjes, F.; Goetschel, F.; Tresch, A.; Beißbarth, T.   & Wiemann, S. et al.​ (2010) 
    Bioinformatics, 26(19) pp. 2480​-2481​.​ DOI: https://doi.org/10.1093/bioinformatics/btq443 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​Mutated KRAS Results in Overexpression of DUSP4, a MAP-Kinase Phosphatase, and SMYD3, a Histone Methyltransferase, in Rectal Carcinomas​
    Gaedcke, J. ; Grade, M. ; Jung, K. ; Camps, J.; Jo, P. ; Emons, G.   & Gehoff, A. et al.​ (2010) 
    Genes Chromosomes and Cancer, 49(11) pp. 1024​-1034​.​ DOI: https://doi.org/10.1002/gcc.20811 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy​
    Gaedcke, J. ; Grade, M. ; Jung, K. ; Schirmer, M. A. ; Jo, P. ; Obermeyer, C. & Wolff, H. A.  et al.​ (2010) 
    Radiotherapy and Oncology, 94(1) pp. 76​-81​.​ DOI: https://doi.org/10.1016/j.radonc.2009.10.001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​A GENE EXPRESSION SIGNATURE FOR CHEMORADIOSENSITIVITY OF COLORECTAL CANCER CELLS​
    Spitzner, M. ; Emons, G. ; Kramer, F. ; Gaedcke, J. ; Rave-Fränk, M. ; Scharf, J.-G. & Burfeind, P.  et al.​ (2010) 
    International Journal of Radiation Oncology*Biology*Physics, 78(4) pp. 1184​-1192​.​ DOI: https://doi.org/10.1016/j.ijrobp.2010.06.023 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification​
    Brase, J. C.; Mannsperger, H. A.; Froehlich, H.; Gade, S.; Schmidt, C. D. ; Wiemann, S. & Beißbarth, T.  et al.​ (2010) 
    Proteome Science, 8 art. 36​.​ DOI: https://doi.org/10.1186/1477-5956-8-36 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Conference Paper | 
    ​ ​Dynamic deterministic effects propagation networks: learning signalling pathways from longitudinal protein array data​
    Bender, C.; Henjes, F.; Froehlich, H.; Wiemann, S.; Korf, U. & Beißbarth, T. ​ (2010)
    Bioinformatics, 26(18) pp. i596​-i602. , Ghent, BELGIUM.
    Oxford​: Oxford Univ Press. DOI: https://doi.org/10.1093/bioinformatics/btq385 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​RPPanalyzer: Analysis of reverse-phase protein array data​
    Mannsperger, H. A.; Gade, S.; Henjes, F.; Beißbarth, T.   & Korf, U.​ (2010) 
    Bioinformatics, 26(17) pp. 2202​-2203​.​ DOI: https://doi.org/10.1093/bioinformatics/btq347 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article
    ​ ​Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer​
    Calabrò, A.; Beißbarth, T. ; Kuner, R.; Stojanov, M.; Benner, A.; Asslaber, M. & Ploner, F. et al.​ (2009) 
    Breast Cancer Research and Treatment, 116(1) pp. 69​-77​.​ DOI: https://doi.org/10.1007/s10549-008-0105-3 
    ​Details  DOI  PMID  PMC 
  • 2009 | Journal Article
    ​ ​Nested effects models for learning signaling networks from perturbation data​
    Fröhlich, H.; Tresch, A. & Beißbarth, T. ​ (2009) 
    Biometrical Journal, 51(2) pp. 304​-323​.​ DOI: https://doi.org/10.1002/bimj.200800185 
    ​Details  DOI  PMID  PMC 
  • 2009 | Journal Article | 
    ​ ​Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance.​
    Sahin, Ö.; Fröhlich, H.; Löbke, C.; Korf, U.; Burmester, S.; Majety, M. & Mattern, J. et al.​ (2009) 
    BMC systems biology, 3 pp. 20​.​ DOI: https://doi.org/10.1186/1752-0509-3-1 
    ​Details  DOI  PMID  PMC 
  • 2009 | Journal Article
    ​ ​Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling​
    Ling, K.-H.; Hewitt, C. A; Beißbarth, T. ; Hyde, L.; Banerjee, K.; Cheah, P.-S. & Cannon, P. Z et al.​ (2009) 
    Genome Biology, 10(10) pp. R104​.​ DOI: https://doi.org/10.1186/gb-2009-10-10-r104 
    ​Details  DOI  PMID  PMC 
  • 2009 | Journal Article | 
    ​ ​Deterministic Effects Propagation Networks for reconstructing protein signaling networks from multiple interventions​
    Froehlich, H.; Sahin, O.; Arlt, D.; Bender, C. & Beißbarth, T. ​ (2009) 
    BMC Bioinformatics, 10 art. 322​.​ DOI: https://doi.org/10.1186/1471-2105-10-322 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article
    ​ ​Relapse-free survival in breast cancer patients is associated with a gene expression signature characteristic for inflammatory breast cancer​
    Van Laere, S.; Beißbarth, T. ; Van der Auwera, I.; Van den Eynden, G.; Trinh, X. B.; Elst, H. & Van Hummelen, P. et al.​ (2008) 
    Clinical Cancer Research, 14(22) pp. 7452​-7460​.​ DOI: https://doi.org/10.1158/1078-0432.CCR-08-1077 
    ​Details  DOI  PMID  PMC 
  • 2008 | Journal Article
    ​ ​Estimating large-scale signaling networks through nested effect models with intervention effects from microarray data​
    Fröhlich, H.; Fellmann, M.; Sültmann, H.; Poustka, A. & Beißbarth, T. ​ (2008) 
    Bioinformatics, 24(22) pp. 2650​-2656​.​ DOI: https://doi.org/10.1093/bioinformatics/btm634 
    ​Details  DOI  PMID  PMC 
  • 2008 | Journal Article
    ​ ​Analyzing gene perturbation screens with nested effects models in R and bioconductor​
    Fröhlich, H.; Beißbarth, T. ; Tresch, A.; Kostka, D.; Jacob, J.; Spang, R. & Markowetz, F.​ (2008) 
    Bioinformatics, 24(21) pp. 2549​-2550​.​ DOI: https://doi.org/10.1093/bioinformatics/btn446 
    ​Details  DOI  PMID  PMC 
  • 2008 | Journal Article
    ​ ​Quantitative protein microarrays for time-resolved measurements of protein phosphorylation​
    Korf, U.; Derdak, S.; Tresch, A.; Henjes, F.; Schumacher, S.; Schmidt, C. & Hahn, B. et al.​ (2008) 
    Proteomics, 8(21) pp. 4603​-4612​.​ DOI: https://doi.org/10.1002/pmic.200800112 
    ​Details  DOI  PMID  PMC 
  • 2008 | Journal Article
    ​ ​Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas​
    Westermann, F.; Muth, D.; Benner, A.; Bauer, T.; Henrich, K.-O.; Oberthuer, A. & Brors, B. et al.​ (2008) 
    Genome Biology, 9(10) pp. R150​.​ DOI: https://doi.org/10.1186/gb-2008-9-10-r150 
    ​Details  DOI  PMID  PMC 
  • 2008 | Journal Article
    ​ ​Predicting pathway membership via domain signatures​
    Fröhlich, H.; Fellmann, M.; Sültmann, H.; Poustka, A. & Beißbarth, T. ​ (2008) 
    Bioinformatics, 24(19) pp. 2137​-2142​.​ DOI: https://doi.org/10.1093/bioinformatics/btn403 
    ​Details  DOI  PMID  PMC 
  • 2008 | Journal Article | 
    ​ ​Integrative analysis of RUNX1 downstream pathways and target genes​
    Michaud, J.; Simpson, K. M; Escher, R.; Buchet-Poyau, K.; Beißbarth, T. ; Carmichael, C. & Ritchie, M. E et al.​ (2008) 
    BMC Genomics, 9(1) pp. 363​.​ DOI: https://doi.org/10.1186/1471-2164-9-363 
    ​Details  DOI  PMID  PMC 
  • 2008 | Journal Article | 
    ​ ​Extending pathways based on gene lists using InterPro domain signatures​
    Hahne, F.; Mehrle, A.; Arlt, D.; Poustka, A.; Wiemann, S. & Beißbarth, T. ​ (2008) 
    BMC Bioinformatics, 9(1) pp. 3​.​ DOI: https://doi.org/10.1186/1471-2105-9-3 
    ​Details  DOI  PMID  PMC 
  • 2008 | Conference Paper
    ​ ​Extending pathways with inferred regulatory interactions from microarray data and protein domain signatures​
    Bender, C.; Fröhlich, H.; Johannes, M. & Beißbarth, T. ​ (2008)
    ​Critical Assessment of Microarray Data Analysis​
    ​Details 
  • 2008 | Journal Article
    ​ ​System-biology for answer of bio-medicinal questions: Metastases and resistance for cancer​
    Arlt, D.; Sahin, Z.; Korf, U.; Loebke, C.; Fröhlich, H.; Sültmann, H. & Beißbarth, T.  et al.​ (2008) 
    Onkologie (Basel), 31 pp. 14​-14​.​
    ​Details 
  • 2008 | Journal Article
    ​ ​A structural investigation into the basis of celiac disease​
    Broughton, S.; Reid, H.; Henderson, K.; Mannering, S.; Chen, Z.; Tye-Din, J. & Beißbarth, T.  et al.​ (2008) 
    Acta Crystallographica. Section A, Foundations and Advances, 64(a1) pp. C232​-C232​.​ DOI: https://doi.org/10.1107/S0108767308092556 
    ​Details  DOI 
  • 2008 | Book Chapter
    ​ ​Antibody microarrays as an experimental platform for the analysis of signal transduction networks​
    Korf, U.; Henjes, F.; Schmidt, C.; Tresch, A.; Mannsperger, H.; Löbke, C.& Beißbarth, T.  et al.​ (2008)
    In: Protein – Protein Interaction pp. 153​-175.  DOI: https://doi.org/10.1007/10_2008_101 
    ​Details  DOI  PMID  PMC 
  • 2007 | Journal Article
    ​ ​Discrimination of direct and indirect interactions in a network of regulatory effects​
    Tresch, A.; Beißbarth, T. ; Sültmann, H.; Kuner, R.; Poustka, A. & Buness, A.​ (2007) 
    Journal of Computational Biology, 14(9) pp. 1217​-1228​.​ DOI: https://doi.org/10.1089/cmb.2007.0085 
    ​Details  DOI  PMID  PMC 
  • 2007 | Journal Article | 
    ​ ​Large scale statistical inference of signaling pathways from RNAi and microarray data​
    Froehlich, H.; Fellmann, M.; Sueltmann, H.; Poustka, A. & Beißbarth, T. ​ (2007) 
    BMC Bioinformatics, 8(1) pp. 386​.​ DOI: https://doi.org/10.1186/1471-2105-8-386 
    ​Details  DOI  PMID  PMC 
  • 2007 | Journal Article
    ​ ​A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease​
    Henderson, K. N; Tye-Din, J. A; Reid, H. H; Chen, Z.; Borg, N. A; Beißbarth, T.   & Tatham, A. et al.​ (2007) 
    Immunity, 27(1) pp. 23​-34​.​ DOI: https://doi.org/10.1016/j.immuni.2007.05.015 
    ​Details  DOI  PMID  PMC 
  • 2007 | Journal Article | 
    ​ ​GOSim: an R-package for computation of information theoretic GO similarities between terms and gene products​
    Fröhlich, H.; Speer, N.; Poustka, A. & Beißbarth, T. ​ (2007) 
    BMC Bioinformatics, 8(1) pp. 166​.​ DOI: https://doi.org/10.1186/1471-2105-8-166 
    ​Details  DOI  PMID  PMC 
  • 2006 | Journal Article
    ​ ​Nedd4-WW domain-binding protein 5 (Ndfip1) is associated with neuronal survival after acute cortical brain injury​
    Sang, Q.; Kim, M. H; Kumar, S.; Bye, N.; Morganti-Kossman, M. C; Gunnersen, J. & Fuller, S. et al.​ (2006) 
    The Journal of Neuroscience, 26(27) pp. 7234​-7244​.​ DOI: https://doi.org/10.1523/JNEUROSCI.1398-06.2006 
    ​Details  DOI  PMID  PMC 
  • 2006 | Conference Paper
    ​ ​Modeling breast cell cycle regulation overcoming drug resistance​
    Arlt, D.; Sahin, O.; Korf, U.; Loebke, C.; Beißbarth, T. ; Hahne, F. & Wiemann, S. et al.​ (2006)
    ​Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society pp. 40​-43. ​Annual International Conference of the IEEE Engineering in Medicine and Biology Society​ DOI: https://doi.org/10.1109/IEMBS.2006.259761 
    ​Details  DOI  PMID  PMC 
  • 2006 | Journal Article
    ​ ​O2-04-07: A Serial Analysis of Gene Expression (SAGE) profile of the Alzheimer's disease TG2576 mouse model​
    George, A. J.; Gordon, L.; Beißbarth, T. ; Koukoulas, I.; Holsinger, R. D.; Perreau, V. & Cappai, R. et al.​ (2006) 
    Alzheimer's & Dementia: The journal of the Alzheimer's Association, 2 pp. S39​-S39​.​ DOI: https://doi.org/10.1016/j.jalz.2006.05.135 
    ​Details  DOI 
  • 2006 | Book Chapter
    ​ ​Interpreting experimental results using gene ontologies​
    Beißbarth, T. ​ (2006)
    In: DNA Microarrays, Part B: Databases and Statistics pp. 340​-352.  DOI: https://doi.org/10.1016/S0076-6879(06)11018-6 
    ​Details  DOI  PMID  PMC 
  • 2005 | Journal Article
    ​ ​A systematic approach for comprehensive T-cell epitope discovery using peptide libraries​
    Beißbarth, T. ; Tye-Din, J. A; Smyth, G. K; Speed, T. P & Anderson, R. P​ (2005) 
    Bioinformatics, 21(Suppl. 1) pp. i29​-i37​.​ DOI: https://doi.org/10.1093/bioinformatics/bti1013 
    ​Details  DOI  PMID  PMC 
  • 2005 | Report
    ​ ​Microarray Analysis of Neurosphere Cells Treated Chromatin Modifying Agents​
    Ruau, D.; Kirchhof, N.; Beißbarth, T. ; Kirsch, R. D.; Schmittwolf, C.; Vingron, M.& Müller, A. M. et al.​ (2005)
    ​Details 
  • 2005 | Report
    ​ ​Recommendations for experimental design of standard experiments​
    Lawerenz, C.; Beißbarth, T. ; Mannsmann, U.& Brors, B.​ (2005)
    ​Details 
  • 2005 | Conference Paper
    ​ ​Comprehensive T-cell epitope characterization in Hla-Dq8 celiac disease​
    Tye-Din, J.; van Heel, D.; Beißbarth, T.   & Anderson, R. P​ (2005)
    Gastroenterology, 128 ​Digestive Disease Week and the 106th Annual Meeting of the American Gastroenterological Association​, Chicago, Illinois.
    ​Details 
  • 2005 | Conference Paper
    ​ ​A comprehensive bioinformatic and functional screen of wheat gluten T-cell epitopes in Hla-Dq2 celiac disease in vivo​
    Tye-Din, J.; Beißbarth, T.   & Anderson, R. P​ (2005)
    Gastroenterology, 128 ​Digestive Disease Week and the 106th Annual Meeting of the American Gastroenterological Association​, Chicago, Illinois.
    ​Details 
  • 2004 | Journal Article
    ​ ​A comparative analysis of transcribed genes in the mouse hypothalamus and neocortex reveals chromosomal clustering​
    Boon, W.-M.; Beißbarth, T. ; Hyde, L.; Smyth, G.; Gunnersen, J.; Denton, D. A & Scott, H. et al.​ (2004) 
    Proceedings of the National Academy of Sciences of the United States of America, 101(41) pp. 14972​-14977​.​ DOI: https://doi.org/10.1073/pnas.0406296101 
    ​Details  DOI  PMID  PMC 
  • 2004 | Journal Article
    ​ ​Statistical modeling of sequencing errors in SAGE libraries​
    Beißbarth, T. ; Hyde, L.; Smyth, G. K; Job, C.; Boon, W.-M.; Tan, S.-S. & Scott, H. S et al.​ (2004) 
    Bioinformatics, 20(Suppl. 1) pp. i31-9​-i39​.​ DOI: https://doi.org/10.1093/bioinformatics/bth924 
    ​Details  DOI  PMID  PMC 
  • 2004 | Journal Article
    ​ ​GOstat: find statistically overrepresented Gene Ontologies within a group of genes​
    Beißbarth, T.   & Speed, T. P​ (2004) 
    Bioinformatics, 20(9) pp. 1464​-1465​.​ DOI: https://doi.org/10.1093/bioinformatics/bth088 
    ​Details  DOI  PMID  PMC 
  • 2004 | Journal Article
    ​ ​cDNA arrays analyses in an animal model for psychosis-related traits​
    Hartmann, A.; Giegling, I.; Beißbarth, T. ; Dames, P. & Rujescu, D.​ (2004) 
    Pharmacopsychiatry, 36(5) pp. 36​-108​.​ DOI: https://doi.org/10.1055/s-2003-825359 
    ​Details  DOI 
  • 2003 | Journal Article
    ​ ​Analysis of CREM-dependent gene expression during mouse spermatogenesis​
    Beißbarth, T. ; Borisevich, I.; Hörlein, A.; Kenzelmann, M.; Hergenhahn, M.; Klewe-Nebenius, A. & Klären, R. et al.​ (2003) 
    Molecular and Cellular Endocrinology, 212(1-2) pp. 29​-39​.​ DOI: https://doi.org/10.1016/j.mce.2003.09.023 
    ​Details  DOI  PMID  PMC 
  • 2002 | Journal Article
    ​ ​Monitoring the switch from housekeeping to pathogen defense metabolism in Arabidopsis thaliana using cDNA arrays​
    Scheideler, M.; Schlaich, N. L.; Fellenberg, K.; Beißbarth, T. ; Hauser, N. C.; Vingron, M. & Slusarenko, A. J et al.​ (2002) 
    The Journal of Biological Chemistry, 277(12) pp. 10555​-10561​.​ DOI: https://doi.org/10.1074/jbc.M104863200 
    ​Details  DOI  PMID  PMC 
  • 2002 | Journal Article
    ​ ​Monitoring the switch from housekeeping to pathogen defense metabolism​
    Scheideler, M.; Schlaich, N. L.; Fellenberg, K.; Beißbarth, T. ; Hauser, N. C.; Vingron, M. & Slusarenko, A. et al.​ (2002) 
    The Journal of Biological Chemistry, 277 pp. 10556​-10561​.​
    ​Details 
  • 2001 | Thesis | Doctoral Thesis
    ​ ​Analysis of transcription factor CREM dependent gene expression during mouse spermatogenesis​
    Beißbarth, T. ​ (2001)
    Universität Heidelberg. 
    Heidelberg​
    ​Details 
  • 2000 | Journal Article
    ​ ​Processing and quality control of DNA array hybridization data​
    Beißbarth, T. ; Fellenberg, K.; Brors, B.; Arribas-Prat, R.; Boer, J.; Hauser, N C & Scheideler, M. et al.​ (2000) 
    Bioinformatics, 16(11) pp. 1014​-1022​.​ DOI: https://doi.org/10.1093/bioinformatics/16.11.1014 
    ​Details  DOI  PMID  PMC 
  • 2000 | Journal Article
    ​ ​Increased efficiency of folding and peptide loading of mutant MHC class I molecules​
    Beißbarth, T. ; Sun, J.; Kavathas, P. B. & Ortmann, B.​ (2000) 
    European Journal of Immunology, 30(4) pp. 1203​-1213​.​ DOI: https://doi.org/10.1002/(SICI)1521-4141(200004)30:4<1203::AID-IMMU1203>3.0.CO;2-L 
    ​Details  DOI 
  • 2000 | Journal Article
    ​ ​GeneNest: automated generation and visualization of gene indices​
    Haas, S. A; Beissbarth, T. ; Rivals, E.; Krause, A. & Vingron, M.​ (2000) 
    Trends in Genetics, 16(11) pp. 521​-523​.​ DOI: https://doi.org/10.1016/S0168-9525(00)02116-8 
    ​Details  DOI  PMID  PMC 

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