Prof. Dr. Björn Chapuy

 
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  • 2020 Journal Article | Research Paper | 
    ​ ​Low serum albumin is an independent risk factor in elderly patients with aggressive B‐cell lymphoma: Results from prospective trials of the German High‐Grade Non‐Hodgkin's Lymphoma Study Group​
    Høhloch, K. ; Ziepert, M.; Trümper, L. ; Buske, C.; Held, G.; Poeschel, V. & Chapuy, B.  et al.​ (2020) 
    eJHaem1(1) pp. 181​-187​.​ DOI: https://doi.org/10.1002/jha2.61 
    Details  DOI 
  • 2016 Journal Article | Research Paper
    ​ ​Modified BEAM with triple autologous stem cell transplantation for patients with relapsed aggressive non-Hodgkin lymphoma​
    Hohloch, K.; Zeynalova, S.; Chapuy, B. ; Pfreundschuh, M.; Loeffler, M.; Ziepert, M. & Feller, A. C. et al.​ (2016) 
    Annals of Hematology95(7) pp. 1121​-1128​.​ DOI: https://doi.org/10.1007/s00277-016-2671-5 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Research Paper
    ​ ​Nuclear Trapping through Inhibition of Exosomal Export by Indomethacin Increases Cytostatic Efficacy of Doxorubicin and Pixantrone​
    Koch, R.; Aung, T.; Vogel, D.; Chapuy, B. ; Wenzel, D.; Becker, S. & Sinzig, U. et al.​ (2016) 
    Clinical Cancer Research22(2) pp. 395​-404​.​ DOI: https://doi.org/10.1158/1078-0432.CCR-15-0577 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Research Paper
    ​ ​Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease​
    Chapuy, B. ; Cheng, H.; Watahiki, A.; Ducar, M. D.; Tan, Y.; Chen, L. & Roemer, M. G. M. et al.​ (2016) 
    Blood127(18) pp. 2203​-2213​.​ DOI: https://doi.org/10.1182/blood-2015-09-672352 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Conference Abstract
    ​ ​SFRP4-Mediated Inhibition of Canonical Wnt-Signaling in DLBCL​
    Koch, R. & Chapuy, B. ​ (2015)
    Blood126(23) ​57th Annual Meeting of the American-Society-of-Hematology​, Orlando, FL.
    Washington​: Amer Soc Hematology.
    Details  WoS 
  • 2015 Conference Abstract
    ​ ​Diffuse Large B-Cell Lymphoma Patient-Derived Xenograft Models Capture Molecular and Biologic Heterogeneity and Inform Therapy​
    Chapuy, B. ; Cheng, H.; Watahiki, A.; Ducar, M. D.; Gusenleitner, D.; Chen, L. & Roemer, M. G. M. et al.​ (2015)
    Blood126(23) ​57th Annual Meeting of the American-Society-of-Hematology​, Orlando, FL.
    Washington​: Amer Soc Hematology.
    Details  WoS 
  • 2015 Conference Abstract
    ​ ​Comprehensive Analyses of Genetic Features Identify Coordinate Signatures in Diffuse Large B-Cell Lymphoma​
    Chapuy, B. ; Dunford, A. J.; Stewart, C.; Kamburov, A.; Kim, J.; Roemer, M. G. M. & Ziepert, M. et al.​ (2015)
    Blood126(23) ​57th Annual Meeting of the American-Society-of-Hematology​, Orlando, FL.
    Washington​: Amer Soc Hematology.
    Details  WoS 
  • 2014 Journal Article | Research Paper
    ​ ​Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma​
    Koch, R.; Demant, M.; Aung, T.; Diering, N.; Cicholas, A.; Chapuy, B.   & Wenzel, D. et al.​ (2014) 
    Blood123(14) pp. 2189​-2198​.​ DOI: https://doi.org/10.1182/blood-2013-08-523886 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper | 
    ​ ​Intracellular ATP-Binding Cassette Transporter A3 is Expressed in Lung Cancer Cells and Modulates Susceptibility to Cisplatin and Paclitaxel​
    Overbeck, T. R.; Hupfeld, T.; Krause, D.; Waldmann-Beushausen, R.; Chapuy, B. ; Guedenzoph, B. & Aung, T. et al.​ (2013) 
    Oncology84(6) pp. 362​-370​.​ DOI: https://doi.org/10.1159/000348884 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article | Research Paper
    ​ ​Tyrosinekinase inhibition facilitates cooperation of transcription factor SALL4 and ABC transporter A3 towards intrinsic CML cell drug resistance​
    Hupfeld, T.; Chapuy, B. ; Schrader, V.; Beutler, M.; Veltkamp, C.; Koch, R. & Cameron, S. et al.​ (2013) 
    British Journal of Haematology161(2) pp. 204​-213​.​ DOI: https://doi.org/10.1111/bjh.12246 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Conference Abstract
    ​ ​The role of vesicular transport in reduced susceptibility of lymphoma cells for humoral immunotherapy​
    Aung, T.; Chapuy, B. ; Vogel, D.; Kiecke, C.; Koch, R.; Wenzel, D. & Oppermann, M. et al.​ (2012)
    Onkologie35 
    Basel​: Karger.
    Details  WoS 
  • 2011 Conference Abstract
    ​ ​Homeostasis of lymphoma side population cells in aggressive B-cell lymphoma​
    Koch, R.; Diering, N.; Lahmann, M.; Demant, M.; Aung, T.; Chapuy, B.   & Becker, S. et al.​ (2011)
    Onkologie34 
    Basel​: Karger.
    Details  WoS 
  • 2011 Conference Abstract
    ​ ​Exosomal shielding of B-cell lymphoma from humoral immunotherapy​
    Thiha, A.; Vogel, D.; Chapuy, B. ; Wenzel, D.; Oppermann, M.; Koch, R. & Hupfeld, T. et al.​ (2011)
    Onkologie34 
    Basel​: Karger.
    Details  WoS 
  • 2011 Conference Abstract
    ​ ​Tyrosinekinase-inhibition modulates ABC transporter A3 mediated susceptibility mechanisms in CML cells involving transcription factor SALL4​
    Hupfeld, T.; Schrader, V.; Chapuy, B. ; Truemper, L. H. & Wulf, G. G.​ (2011)
    Onkologie34 
    Basel​: Karger.
    Details  WoS 
  • 2011 Journal Article | Research Paper
    ​ ​Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3​
    Aung, T.; Chapuy, B. ; Vogel, D.; Wenzel, D.; Oppermann, M.; Lahmann, M. & Weinhage, T. et al.​ (2011) 
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA108(37) pp. 15336​-15341​.​ DOI: https://doi.org/10.1073/pnas.1102855108 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper
    ​ ​Multikinase inhibitor sorafenib exerts cytocidal efficacy against Non-Hodgkin lymphomas associated with inhibition of MAPK14 and AKT phosphorylation​
    Chapuy, B. ; Schuelper, N. ; Panse, M.; Dohm, A. ; Hand, E.; Schroers, R. & Truemper, L. H. et al.​ (2011) 
    British Journal of Haematology152(4) pp. 401​-412​.​ DOI: https://doi.org/10.1111/j.1365-2141.2010.08526.x 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Conference Abstract
    ​ ​Impact of imatinib on expression and function of intracellular ABC transporter A3 in chronic myeloid leukemia cells and susceptibility to this drug​
    Hupfeld, T.; Chapuy, B. ; Schrader, V.; Truemper, L. H. & Wulf, G. G.​ (2010)
    Onkologie33 
    Basel​: Karger.
    Details  WoS 
  • 2010 Conference Abstract
    ​ ​Putative tumor stem cells of SP phenotype in aggressive B-cell lymphoma​
    Diering, N. ; Aung, T.; Chapuy, B. ; Koch, R.; Becker, S.; Krause, D. & Truemper, L. H. et al.​ (2010)
    Onkologie33 
    Basel​: Karger.
    Details  WoS 
  • 2009 Journal Article | 
    ​ ​A rare cause of sudden cardiac arrest: primary cardiac lymphoma​
    Dellas, C. ; Chapuy, B. ; Schweyer, S.; Hasenfuß, G.   & Huenlich, M. ​ (2009) 
    Clinical Research in Cardiology98(8) pp. 509​-511​.​ DOI: https://doi.org/10.1007/s00392-009-0034-0 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | Research Paper
    ​ ​Characterization of HLA-DR-restricted T-cell epitopes derived from human proteinase 3​
    Piesche, M.; Hildebrandt, Y.; Chapuy, B. ; Wulf, G. G. ; Truemper, L. H.   & Schroers, R.​ (2009) 
    Vaccine27(34) pp. 4718​-4723​.​ DOI: https://doi.org/10.1016/j.vaccine.2009.05.010 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | Research Paper | 
    ​ ​ABC transporter A3 facilitates lysosomal sequestration of imatinib and modulates susceptibility of chronic myeloid leukemia cell lines to this drug​
    Chapuy, B. ; Panse, M.; Radunski, U.; Koch, R.; Wenzel, D.; lnagaki, N. & Haase, D. et al.​ (2009) 
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL94(11) pp. 1528​-1536​.​ DOI: https://doi.org/10.3324/haematol.2009.008631 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Conference Abstract
    ​ ​Expression of intracellular ABC transporter A3 in aggressive non-Hodgkin lymphoma​
    Chapuy, B. ; Corsham, S.; Klapper, W.; Ziepert, M.; Truemper, L. H. & Wulf, G.​ (2008)
    Annals of Oncology19 pp. 199​-200. ​10th International Conference on Malignant Lymphoma​, Lugano, SWITZERLAND.
    Oxford​: Oxford Univ Press.
    Details  WoS 
  • 2008 Conference Abstract
    ​ ​NK cells cytotoxicity: inhibition by inappropriate HLA class I and overcoming hyporesponsiveness​
    Hasenkamp, J.; Borgerding, A.; Chapuy, B. ; Jung, W.; Wulf, G.; Truemper, L. H. & Glass, B.​ (2008)
    Bone Marrow Transplantation41 ​34th Annual Meeting of the European-Group-for-Blood-and-Marrow-Transplantation/24nd Meeting of the EBMT-Nurses-Group/7th Meeting of the EBMT-Data-Management-Group​, Florence, ITALY.
    London​: Nature Publishing Group.
    Details  WoS 
  • 2008 Conference Abstract
    ​ ​SEQUENTIAL FISH-ANALYSES OF CIRCULATING CD34+-CELLS IN MDS - A SUITABLE METHOD FOR CYTOGENETIC MONITORING UNDER S-AZACYTIDINE OR LENALIDOMIDE​
    Braulke, F.; Steffens, R.; Schuetze, C.; Plischke, K.; Chapuy, B.   & Haase, D.​ (2008)
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL93 pp. 286​-287. ​13th Congress of the European-Hematology-Association​, Copenhagen, DENMARK.
    Pavia​: Ferrata Storti Foundation.
    Details  WoS 
  • 2008 Journal Article | Research Paper | 
    ​ ​Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration​
    Chapuy, B. ; Koch, R.; Radunski, U.; Corsham, S.; Cheong, N.; Inagaki, N. & Ban, N. et al.​ (2008) 
    Leukemia22(8) pp. 1576​-1586​.​ DOI: https://doi.org/10.1038/leu.2008.103 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | Research Paper
    ​ ​AP-1 and AP-3 mediate sorting of melanosomal and lysosomal membrane proteins into distinct post-Golgi trafficking pathways​
    Chapuy, B. ; Tikkanen, R.; Muehlhausen, C.; Wenzel, D.; von Figura, K. & Hoening, S.​ (2008) 
    Traffic9(7) pp. 1157​-1172​.​ DOI: https://doi.org/10.1111/j.1600-0854.2008.00745.x 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Conference Abstract
    ​ ​The intracellular ABC transporterA3 contributes to imatinib resistance of CML cells by subcellular sequestration​
    Chapuy, B. ; Albrecht, M.; Radunski, U.; Koch, R.; Haase, D.; Truemper, L. H. & Wulf, G. G.​ (2007)
    Blood110(11) ​49th Annual Meeting of the American-Society-of-Hematology​, Atlanta, GA.
    Washington​: Amer Soc Hematology.
    Details  WoS 
  • 2007 Conference Abstract
    ​ ​A distal single nueleotide polymorphism disrupts development-dependent long-range transcriptional regulation of the PU.1 gene through the chromatin-remodeling protein SATB1 in acute myeloid leukemia​
    Steidl, U.; Steidl, C.; Ebralidze, A.; Chapuy, B. ; Han, H.-J.; Will, B. & Rosenbauer, F. et al.​ (2007)
    Blood110(11) ​49th Annual Meeting of the American-Society-of-Hematology​, Atlanta, GA.
    Washington​: Amer Soc Hematology.
    Details  WoS 
  • 2007 Conference Abstract
    ​ ​Incidence of allo-reactive NK cells after allogeneic haematopoietic stem cell transplantation​
    Hasenkamp, J.; Missal, I.; Borgerding, A.; Falk, C. S.; Wommelsdorf, T.; Dingeldein, S. & Chapuy, B.  et al.​ (2007)
    Bone Marrow Transplantation39 ​33rd Annual Meeting of the European-Group-for-Blood-and-Marrow-Transplantation​, Lyon, FRANCE.
    London​: Nature Publishing Group.
    Details  WoS 
  • 2007 Journal Article | Research Paper
    ​ ​Identification of a promiscuous HLA DR-restricted T-cell epitope derived from the inhibitor of apoptosis protein survivin​
    Piesche, M.; Hildebrandt, Y.; Zettl, F.; Chapuy, B. ; Schmitz, M.; Wulf, G. & Truemper, L. H. et al.​ (2007) 
    Human Immunology68(7) pp. 572​-576​.​ DOI: https://doi.org/10.1016/j.humimm.2007.03.007 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article
    ​ ​A distal single nucleotide polymorphism alters long-range reguiavon of the PU-1 gene in acute myeloid leukemia​
    Steidl, U.; Steidl, C.; Ebralidze, A.; Chapuy, B. ; Han, H.-J.; Will, B. & Rosenbauer, F. et al.​ (2007) 
    Journal of Clinical Investigation117(9) pp. 2611​-2620​.​ DOI: https://doi.org/10.1172/JCI30525 
    Details  DOI  PMID  PMC  WoS 
  • 2007 Journal Article | Research Paper
    ​ ​Asymptomatic 32 year old female smoker with persistent polyclonal lymphocytosis​
    Chapuy, B. ; Wulf, G.; Tessen, H. W.; Griesinger, F.; Truemper, L. H. & Schroers, R.​ (2007) 
    Der Internist48(3) pp. 314​-318​.​ DOI: https://doi.org/10.1007/s00108-007-1800-6 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article | Research Paper
    ​ ​CD45 monoclonal antibody-mediated cytolysis of human NK and T lymphoma cells​
    Wulf, G. G.; Boehnke, A.; Chapuy, B. ; Glass, B.; Hemmerlein, B.; Schroers, R. & Brenner, M. K. et al.​ (2006) 
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL91(7) pp. 886​-894​.​
    Details  PMID  PMC  WoS 
  • 2006 Conference Abstract
    ​ ​Hematopoietic and endothelial progenitor cells from mouse adult testis derived stem cell lines.​
    Schreiter, J.; Guan, K.; Nayemia, K.; Chapuy, B. ; Truemper, L. H.; Hasenfuß, G.   & Engel, W. et al.​ (2006)
    Blood108(11) , Orlando, FL.
    Washington​: Amer Soc Hematology.
    Details  WoS 
  • 2006 Conference Abstract
    ​ ​Sweet-like bullous skin infiltrations in a chronic myeloic leucemia patient treated with tyrosine kinase inhibitors​
    Kaune, K. M.; Chapuy, B. ; Steidl, C.; Ressel, A.; Baesecke, J.; Glass, B. & Neumann, C. et al.​ (2006)
    Experimental Dermatology15(3) pp. 220​-221. ​33rd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF)​, Aachen, GERMANY.
    Oxford​: Blackwell Publishing.
    Details  WoS 
  • 2006 Conference Abstract
    ​ ​Sweet-like bullous skin infiltrations in a CML patient treated with tyrosine kinase inhibitors​
    Kaune, K. M.; Baumgart, M.; Gesk, S.; Chapuy, B. ; Baesecke, J.; GlaB, B. & Siebert, R. et al.​ (2006)
    Journal of Investigative Dermatology126 ​36th Annual Meeting of the European-Society-of-Dermatology-Research (ESDR)​, Paris, FRANCE.
    New york​: Nature Publishing Group.
    Details  WoS 
  • 2006 Conference Abstract
    ​ ​ABCA3 expression in AML blast cells: Association with poor disease outcome and intracellular drug sequestration.​
    Chapuy, B. ; Radunski, U.; Corsham, S.; Koch, R.; Cheong, N.; Inagaki, N. & Griesinger, F. et al.​ (2006)
    Blood108(11) ​48th Annual Meeting of the American-Society-of-Hematology​, Orlando, FL.
    Washington​: Amer Soc Hematology.
    Details  WoS 
  • 2006 Conference Abstract
    ​ ​Allo-reactive NK cells after HLA-matched allogeneic hematopoietic stem cell transplantation.​
    Hasenkamp, J.; Borgerding, A.; Chapuy, B. ; Wulf, G.; Missal, I.; Jung, W. & Truemper, L. H. et al.​ (2006)
    Blood108(11) ​48th Annual Meeting of the American-Society-of-Hematology​, Orlando, FL.
    Washington​: Amer Soc Hematology.
    Details  WoS 
  • 2006 Conference Abstract
    ​ ​Response to re-treatment with rituximab plus salvage-chemotherapy in refractory or relapsed aggressive Non-Hodgkin's lymphoma.​
    Borgerding, A.; Hasenkamp, J.; Chapuy, B. ; Truemper, L. H.; Wulf, G. & Glass, B.​ (2006)
    Blood108(11) pp. 262B​-263B. ​48th Annual Meeting of the American-Society-of-Hematology​, Orlando, FL.
    Washington​: Amer Soc Hematology.
    Details  WoS 
  • 2006 Journal Article | Research Paper
    ​ ​Mesenchymal stem cells from bone marrow. Phenotype, aspects of biology, and clinical perspectives​
    Wulf, G. G.; Chapuy, B.   & Truemper, L. H.​ (2006) 
    MEDIZINISCHE KLINIK101(5) pp. 408​-413​.​ DOI: https://doi.org/10.1007/s00063-006-1052-6 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article | Research Paper
    ​ ​Reduced intensity conditioning and allogeneic stem cell transplantation after salvage therapy integrating alemtuzumab for patients with relapsed peripheral T-cell non-Hodgkin's lymphoma​
    Wulf, G. G. ; Hasenkamp, J. ; Jung, W.; Chapuy, B. ; Truemper, L. H. & Glass, B.​ (2005) 
    Bone Marrow Transplantation36(3) pp. 271​-273​.​ DOI: https://doi.org/10.1038/sj.bmt.1705036 
    Details  DOI  PMID  PMC  WoS 

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