Franc Llorens

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  • 2021 | Journal Article
    ​ ​Creus-Muncunill, Jordi, Anna Guisado-Corcoll, Veronica Venturi, Lorena Pantano, Georgia Escaramís, Marta García de Herreros, Maria Solaguren-Beascoa et al. "Huntington’s disease brain-derived small RNAs recapitulate associated neuropathology in mice​." ​Acta Neuropathologica ​141, no. 4 (2021): ​565​-584​. ​https://doi.org/10.1007/s00401-021-02272-9.
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Podlesniy, Petar, Franc Llorens, Margalida Puigròs, Nuria Serra, Diego Sepúlveda-Falla, Christian Schmidt, Peter Hermann, Inga Zerr, and Ramon Trullas. "Cerebrospinal Fluid Mitochondrial DNA in Rapid and Slow Progressive Forms of Alzheimer’s Disease​." ​International Journal of Molecular Sciences ​21, no. 17 (2020): ​6298​. ​https://doi.org/10.3390/ijms21176298.
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Llorens, Franc, Peter Hermann, Anna Villar-Piqué, Daniela Diaz-Lucena, Katarina Nägga, Oskar Hansson, Isabel Santana et al. "Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia​." ​Nature Communications ​11, no. 1 (2020): . ​https://doi.org/10.1038/s41467-020-14373-2.
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Zerr, Inga, Maria Cramm, Susana Margarida da Silva Correia, Saima Zafar, Anna Villar-Piqué, Franc Llorens, and Matthias Schmitz. "Optimization of the Real-Time Quaking-Induced Conversion Assay for Prion Disease Diagnosis​." ​Frontiers in Bioengineering and Biotechnology ​8 (2020): . ​https://doi.org/10.3389/fbioe.2020.586890.
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Andrés-Benito, Pol, Mònica Povedano, Raúl Domínguez, Carla Marco, Maria J. Colomina, Óscar López-Pérez, Isabel Santana et al. "Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral Sclerosis​." ​International Journal of Molecular Sciences ​21, no. 22 (2020): ​8680​. ​https://doi.org/10.3390/ijms21228680.
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Llorens, Franc, Anna Villar-Piqué, Peter Hermann, Matthias Schmitz, Olga Calero, Christiane Stehmann, Shannon Sarros et al. "Diagnostic Accuracy of Prion Disease Biomarkers in Iatrogenic Creutzfeldt-Jakob Disease​." ​Biomolecules ​10, no. 2 (2020): ​290​. ​https://doi.org/10.3390/biom10020290.
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Candelise, Niccolo, Matthias Schmitz, Katrin Thüne, Maria Cramm, Alberto Rabano, Saima Zafar, Erik Stoops et al. "Effect of the micro-environment on α-synuclein conversion and implication in seeded conversion assays​." ​Translational Neurodegeneration ​9, no. 1 (2020): . ​https://doi.org/10.1186/s40035-019-0181-9.
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Lidón, Laia, Laura Urrea, Franc Llorens, Vanessa Gil, Ignacio Alvarez, Monica Diez-Fairen, Miguel Aguilar et al. "Disease-Specific Changes in Reelin Protein and mRNA in Neurodegenerative Diseases​." ​Cells ​9, no. 5 (2020): ​1252​. ​https://doi.org/10.3390/cells9051252.
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Arora, Amandeep Singh, Saima Zafar, Umair Latif, Franc Llorens, Sabine Mihm, Prateek Kumar, Waqas Tahir et al. "The role of cellular prion protein in lipid metabolism in the liver​." ​Prion ​14, no. 1 (2020): ​95​-108​. ​https://doi.org/10.1080/19336896.2020.1729074.
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Minikel, Eric Vallabh, Eric Kuhn, Alexandra R. Cocco, Sonia M. Vallabh, Christina R. Hartigan, Andrew G. Reidenbach, Jiri G. Safar et al. "Domain-specific Quantification of Prion Protein in Cerebrospinal Fluid by Targeted Mass Spectrometry​." ​Molecular & Cellular Proteomics ​18, no. 12 (2019): ​2388​-2400​. ​https://doi.org/10.1074/mcp.RA119.001702.
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Thüne, Katrin, Matthias Schmitz, Anna Villar-Piqué, Hermann Clemens Altmeppen, Markus Schlomm, Saima Zafar, Markus Glatzel, Franc Llorens, and Inga Zerr. "The cellular prion protein and its derived fragments in human prion diseases and their role as potential biomarkers​." ​Expert review of molecular diagnostics ​19, no. 11 (2019): ​1007​-1018​. ​https://doi.org/10.1080/14737159.2019.1667231.
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Vallabh, Sonia M., Chloe K. Nobuhara, Franc Llorens, Inga Zerr, Piero Parchi, Sabina Capellari, Eric Kuhn et al. "Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development​." ​Proceedings of the National Academy of Sciences ​116, no. 16 (2019): ​7793​-7798​. ​https://doi.org/10.1073/pnas.1901947116.
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Schmitz, Matthias, Niccolo Candelise, Eirini Kanata, Franc Llorens, Katrin Thüne, Anna Villar-Piqué, Susana Margarida da Silva Correia et al. "Validation of Poly(Propylene Imine) Glycodendrimers Towards Their Anti-prion Conversion Efficiency​." ​Molecular Neurobiology ​57, no. 4 (2019): ​1863​-1874​. ​https://doi.org/10.1007/s12035-019-01837-w.
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Zerr, Inga, Anna Villar-Piqué, Vanda Edit Schmitz, Anna Poleggi, Maurizio Pocchiari, Raquel Sánchez-Valle, Miguel Calero et al. "Evaluation of Human Cerebrospinal Fluid Malate Dehydrogenase 1 as a Marker in Genetic Prion Disease Patients​." ​Biomolecules ​9, no. 12 (2019): ​800​. ​https://doi.org/10.3390/biom9120800.
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Villar-Piqué, Anna, Matthias Schmitz, Peter Hermann, Stefan Goebel, Timothy Bunck, Daniela Varges, Isidre Ferrer, Joachim Riggert, Franc Llorens, and Inga Zerr. "Plasma YKL-40 in the spectrum of neurodegenerative dementia​." ​Journal of Neuroinflammation ​16, no. 1 (2019): ​145​. ​https://doi.org/10.1186/s12974-019-1531-3.
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Schmitz, Matthias, Anna Villar-Piqué, Franc Llorens, Karin Gmitterová, Peter Hermann, Daniela Varges, Saima Zafar et al. "Cerebrospinal Fluid Total and Phosphorylated α-Synuclein in Patients with Creutzfeldt–Jakob Disease and Synucleinopathy​." ​Molecular Neurobiology ​56, no. 5 (2018): ​3476​-3483​. ​https://doi.org/10.1007/s12035-018-1313-4.
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Villar-Piqué, Anna, Matthias Schmitz, Niccolò Candelise, Salvador Ventura, Franc Llorens, and Inga Zerr. "Molecular and Clinical Aspects of Protein Aggregation Assays in Neurodegenerative Diseases​." ​Molecular Neurobiology ​55, no. 9 (2018): ​7588​-7605​. ​https://doi.org/10.1007/s12035-018-0926-y.
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Gmitterová, Karin, Joanna Gawinecka, Franc Llorens, Daniela Varges, Peter Valkovič, and Inga Zerr. "Cerebrospinal fluid markers analysis in the differential diagnosis of dementia with Lewy bodies and Parkinson’s disease dementia​." ​European Archives of Psychiatry and Clinical Neuroscience ​270, no. 4 (2018): ​461​-470​. ​https://doi.org/10.1007/s00406-018-0928-9.
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Llorens, Franc, Niels Kruse, André Karch, Matthias Schmitz, Saima Zafar, Nadine Gotzmann, Ting Sun et al. "Validation of α-Synuclein as a CSF Biomarker for Sporadic Creutzfeldt-Jakob Disease​." ​Molecular Neurobiology ​55, no. 3 (2018): ​2249​-2257​. ​https://doi.org/10.1007/s12035-017-0479-5.
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Llorens, Franc, Katrin Thüne, Eulàlia Martí, Eirini Kanata, Dimitra Dafou, Daniela Díaz-Lucena, Ana Vivancos et al. "Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis​." ​PLOS Pathogens ​14, no. 1 (2018): ​e1006802​. ​https://doi.org/10.1371/journal.ppat.1006802.
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Llorens, Franc, Niels Kruse, Matthias Schmitz, Nadine Gotzmann, Ewa Golanska, Katrin Thüne, Orgeta Zejneli et al. "Evaluation of α-synuclein as a novel cerebrospinal fluid biomarker in different forms of prion diseases​." ​Alzheimer's & Dementia: The Journal of the Alzheimer's Association ​13, no. 6 (2017): ​710​-719​. ​https://doi.org/10.1016/j.jalz.2016.09.013.
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | 
    ​ ​Llorens, Franc, Andre Fischer, Katrin Thüne, Beata Sikorska, Matthias Schmitz, Waqas Tahir, Natalia Fernández-Borges et al. "Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease​." ​Acta Neuropathologica Communication ​5, no. 35 (2017): ​1​-20​. ​https://doi.org/10.1186/s40478-017-0431-y.
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Llorens, Franc, Juan-José Zarranz, Andre Fischer, Inga Zerr, and Isidro Ferrer. "Fatal Familial Insomnia: Clinical Aspects and Molecular Alterations​." ​Current Neurology and Neuroscience Reports ​17, no. 4 (2017): . ​https://doi.org/10.1007/s11910-017-0743-0.
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Llorens, Franc, Matthias Schmitz, Tobias Knipper, Christian Schmidt, Peter Lange, André Fischer, Peter Hermann, and Inga Zerr. "Cerebrospinal Fluid Biomarkers of Alzheimer's Disease Show Different but Partially Overlapping Profile Compared to Vascular Dementia​." ​Frontiers in aging neuroscience ​9 (2017): ​289​. ​https://doi.org/10.3389/fnagi.2017.00289.
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article
    ​ ​Frau-Méndez, Margalida A., Iván Fernández-Vega, Belén Ansoleaga, Rosa Blanco Tech, Margarita Carmona Tech, Jose Antonio del Rio, Inga Zerr, Franc Llorens, Juan José Zarranz, and Isidro Ferrer. "Fatal familial insomnia: mitochondrial and protein synthesis machinery decline in the mediodorsal thalamus​." ​Brain Pathology ​27, no. 1 (2016): ​95​-106​. ​https://doi.org/10.1111/bpa.12408.
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Tahir, Waqas, Saima Zafar, Franc Llorens, Amandeep Singh Arora, Katrin Thüne, Matthias Schmitz, Nadine Gotzmann et al. "Molecular Alterations in the Cerebellum of Sporadic Creutzfeldt–Jakob Disease Subtypes with DJ-1 as a Key Regulator of Oxidative Stress​." ​Molecular Neurobiology ​55, no. 1 (2016): ​517​-537​. ​https://doi.org/10.1007/s12035-016-0294-4.
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Mata, Agata, Laura Urrea, Silvia Vilches, Franc Llorens, Katrin Thüne, Juan-Carlos Espinosa, Olivier Andréoletti et al. "Reelin Expression in Creutzfeldt-Jakob Disease and Experimental Models of Transmissible Spongiform Encephalopathies​." ​Molecular Neurobiology ​54, no. 8 (2016): ​6412​-6425​. ​https://doi.org/10.1007/s12035-016-0177-8.
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Schmitz, Matthias, Kathrin Dittmar, Franc Llorens, Ellen Gelpi, Isidre Ferrer, Walter J. Schulz-Schaeffer, and Inga Zerr. "Hereditary Human Prion Diseases: an Update​." ​Molecular Neurobiology ​54, no. 6 (2016): ​4138​-4149​. ​https://doi.org/10.1007/s12035-016-9918-y.
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Schmitz, Matthias, Maria Cramm, Franc Llorens, Dominik Müller-Cramm, Steven Collins, Ryuichiro Atarashi, Katsuya Satoh et al. "The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases​." ​Nature Protocols ​11, no. 11 (2016): ​2233​-2242​. ​https://doi.org/10.1038/nprot.2016.120.
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Karch, André, Franc Llorens, Matthias Schmitz, Amandeep Singh Arora, Saima Zafar, Peter Lange, Christian Schmidt, and Inga Zerr. "Stratification by Genetic and Demographic Characteristics Improves Diagnostic Accuracy of Cerebrospinal Fluid Biomarkers in Rapidly Progressive Dementia​." ​Journal of Alzheimer's Disease ​54, no. 4 (2016): ​1385​-1393​. ​https://doi.org/10.3233/JAD-160267.
    ​Details  DOI 

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