Dr. rer. nat. Lukas Cyganek

 
Staff Status
unigoe
 

1-11 of 11
 
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  • 2022 Journal Article | Research Paper | 
    ​ ​Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration​
    Li, W.; Luo, X.; Poetsch, M. S.; Oertel, R.; Nichani, K.; Schneider, M. & Strano, A. et al.​ (2022) 
    Pharmaceuticals15(2).​ DOI: https://doi.org/10.3390/ph15020220 
    Details  DOI 
  • 2022 Journal Article | Research Paper | 
    ​ ​A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming​
    Lyra-Leite, D. M.; Gutiérrez-Gutiérrez, Ó.; Wang, M.; Zhou, Y.; Cyganek, L.   & Burridge, P. W.​ (2022) 
    STAR Protocols3(3) art. 101560​.​ DOI: https://doi.org/10.1016/j.xpro.2022.101560 
    Details  DOI 
  • 2022 Preprint
    ​ ​Alteration of myocardial structure and function in RAF1-associated Noonan syndrome: Insights from cardiac disease modeling based on patient-derived iPSCs​
    Nakhaei-Rad, S.; Bazgir, F.; Dahlmann, J.; Busley, A. V.; Buchholzer, M.; Haghighi, F.& Schänzer, A. et al.​ (2022). DOI: https://doi.org/10.1101/2022.01.22.477319 
    Details  DOI 
  • 2021 Journal Article | Research Paper | 
    ​ ​TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes​
    Sattler, K.; El-Battrawy, I.; Cyganek, L. ; Lang, S.; Lan, H.; Li, X. & Zhao, Z. et al.​ (2021) 
    Scientific Reports11(1) art. 14689​.​ DOI: https://doi.org/10.1038/s41598-021-93958-3 
    Details  DOI 
  • 2021 Journal Article | Research Paper | 
    ​ ​Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation​
    Schoger, E.; Zimmermann, W.-H. ; Cyganek, L.   & Zelarayán, L. C. ​ (2021) 
    Stem Cell Research56 art. S1873506121003652​.​ DOI: https://doi.org/10.1016/j.scr.2021.102518 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​Monitoring mitochondrial translation in living cells​
    Yousefi, R.; Fornasiero, E. F ; Cyganek, L. ; Montoya, J.; Jakobs, S. ; Rizzoli, S. O   & Rehling, P.  et al.​ (2021) 
    EMBO reports22(4).​ DOI: https://doi.org/10.15252/embr.202051635 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7 ‐related osteopetrosis​
    Rössler, U.; Hennig, A. F.; Stelzer, N.; Bose, S.; Kopp, J.; Søe, K. & Cyganek, L.  et al.​ (2021) 
    Journal of Bone and Mineral Research36(8) pp. 1621​-1635​.​ DOI: https://doi.org/10.1002/jbmr.4322 
    Details  DOI  PMID  PMC 
  • 2021 Journal Article | Research Paper | 
    ​ ​Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression​
    Schoger, E.; Zimmermann, W.-H. ; Cyganek, L.   & Zelarayán, L. C. ​ (2021) 
    Stem Cell Research55 art. S1873506121003202​.​ DOI: https://doi.org/10.1016/j.scr.2021.102473 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper | 
    ​ ​Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes​
    Kleinsorge, M. & Cyganek, L. ​ (2020) 
    STAR Protocols1(1) art. 100026​.​ DOI: https://doi.org/10.1016/j.xpro.2020.100026 
    Details  DOI  PMID  PMC 
  • 2020 Journal Article | Research Paper
    ​ ​Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome–Associated Cardiomyopathy​
    Hanses, U.; Kleinsorge, M.; Roos, L.; Yigit, G. ; Li, Y. ; Barbarics, B. & El-Battrawy, I. et al.​ (2020) 
    Circulation142(11) pp. 1059​-1076​.​ DOI: https://doi.org/10.1161/CIRCULATIONAHA.119.044794 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article | Research Paper | 
    ​ ​Deep phenotyping of human induced pluripotent stem cell–derived atrial and ventricular cardiomyocytes​
    Cyganek, L. ; Tiburcy, M. ; Sekeres, K.; Gerstenberg, K.; Bohnenberger, H. ; Lenz, C.   & Henze, S.  et al.​ (2018) 
    JCI Insight3(12) art. e99941​.​ DOI: https://doi.org/10.1172/jci.insight.99941 
    Details  DOI  PMID  PMC 

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