Dr. rer. nat. Melanie Spitzner

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unigoe
 

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  • 2022 | Journal Article | 
    ​ ​Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair​
    Bolgi, O.; Silva‐Garcia, M.; Ross, B.; Pilla, E.; Kari, V. ; Killisch, M. & Spitzner, M.  et al.​ (2022) 
    EMBO reports,.​ DOI: https://doi.org/10.15252/embr.202154136 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​NOTCH Activation via gp130/STAT3 Signaling Confers Resistance to Chemoradiotherapy​
    Koerdel, K.; Spitzner, M. ; Meyer, T. ; Engels, N.; Krause, F.; Gaedcke, J.   & Conradi, L.-C.  et al.​ (2021) 
    Cancers, 13(3) pp. 455​.​ DOI: https://doi.org/10.3390/cancers13030455 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Hepatic arterial infusion of irinotecan and EmboCept® S results in high tumor concentration of SN-38 in a rat model of colorectal liver metastases​
    Kauffels, A. ; Kitzmüller, M.; Gruber, A.; Nowack, H.; Bohnenberger, H. ; Spitzner, M.   & Kuthning, A. et al.​ (2019) 
    Clinical & Experimental Metastasis, 36(1) pp. 57​-66​.​ DOI: https://doi.org/10.1007/s10585-019-09954-5 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling​
    Emons, G. ; Spitzner, M. ; Reineke, S. ; Möller, J.; Auslander, N.; Kramer, F.   & Hu, Y. et al.​ (2017) 
    Molecular Cancer Research, 15(11) pp. 1481​-1490​.​ DOI: https://doi.org/10.1158/1541-7786.MCR-17-0205 
    ​Details  DOI  PMID  PMC 
  • 2014 | Journal Article
    ​ ​STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo​
    Spitzner, M. ; Roesler, B.; Bielfeld, C.; Emons, G. ; Gaedcke, J. ; Wolff, H. A.   & Rave-Fränk, M.  et al.​ (2014) 
    International Journal of Cancer, 134(4) pp. 997​-1007​.​ DOI: https://doi.org/10.1002/ijc.28429 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy​
    Kendziorra, E.; Ahlborn, K.; Spitzner, M. ; Rave-Fränk, M. ; Emons, G. ; Gaedcke, J.   & Kramer, F.  et al.​ (2011) 
    Carcinogenesis, 32(12) pp. 1824​-1831​.​ DOI: https://doi.org/10.1093/carcin/bgr222 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets​
    Grade, M. ; Hummon, A. B.; Camps, J.; Emons, G. ; Spitzner, M. ; Gaedcke, J.   & Hoermann, P. et al.​ (2011) 
    International Journal of Cancer, 128(5) pp. 1069​-1079​.​ DOI: https://doi.org/10.1002/ijc.25453 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article | 
    ​ ​A GENE EXPRESSION SIGNATURE FOR CHEMORADIOSENSITIVITY OF COLORECTAL CANCER CELLS​
    Spitzner, M. ; Emons, G. ; Kramer, F. ; Gaedcke, J. ; Rave-Fränk, M. ; Scharf, J.-G. & Burfeind, P.  et al.​ (2010) 
    International Journal of Radiation Oncology*Biology*Physics, 78(4) pp. 1184​-1192​.​ DOI: https://doi.org/10.1016/j.ijrobp.2010.06.023 
    ​Details  DOI  PMID  PMC  WoS 

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