Coming together to define membrane contact sites
2019 | journal article; overview
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Cite this publication
Scorrano, L., De Matteis, M. A., Emr, S., Giordano, F., Hajnóczky, G., Kornmann, B., Lackner, L. L. ... Schuldiner, M. (2019). Coming together to define membrane contact sites. Nature Communications, 10(1), 1287. doi: https://doi.org/10.1038/s41467-019-09253-3
Documents & Media
Details
- Authors
- Scorrano, Luca; De Matteis, Maria Antonietta; Emr, Scott; Giordano, Francesca; Hajnóczky, György; Kornmann, Benoît; Lackner, Laura L.; Levine, Tim P.; Pellegrini, Luca; Reinisch, Karin; Rizzuto, Rosario; Simmen, Thomas; Stenmark, Harald; Ungermann, Christian; Schuldiner, Maya
- Abstract
- Close proximities between organelles have been described for decades. However, only recently a specific field dealing with organelle communication at membrane contact sites has gained wide acceptance, attracting scientists from multiple areas of cell biology. The diversity of approaches warrants a unified vocabulary for the field. Such definitions would facilitate laying the foundations of this field, streamlining communication and resolving semantic controversies. This opinion, written by a panel of experts in the field, aims to provide this burgeoning area with guidelines for the experimental definition and analysis of contact sites. It also includes suggestions on how to operationally and tractably measure and analyze them with the hope of ultimately facilitating knowledge production and dissemination within and outside the field of contact-site research.
- Issue Date
- 2019
- Journal
- Nature Communications
- Project
- SFB 1190: Transportmaschinen und Kontaktstellen zellulärer Kompartimente
SFB 1190 | P11: Zuordnung zellulärer Kontaktstellen und deren Zusammenspiel - Working Group
- RG Schuldiner (Functional Genomics of Organelles)
- External URL
- https://sfb1190.med.uni-goettingen.de/production/literature/publications/84
- ISSN
- 2041-1723
- Language
- English