Nanoscopy in a Living Mouse Brain

2012 | journal article; research paper. A publication with affiliation to the University of Göttingen.

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​Berning, S., Willig, K. I., Steffens, H., Dibaj, P. & Hell, S. (2012). ​Nanoscopy in a Living Mouse Brain. Science, 335(6068), ​551​-551​. ​doi: https://doi.org/10.1126/science.1215369 

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Authors
Berning, Sebastian ; Willig, Katrin I. ; Steffens, Heinz ; Dibaj, Payam ; Hell, Stefan 
Abstract
We demonstrated superresolution optical microscopy in a living higher animal. Stimulated emission depletion (STED) fluorescence nanoscopy reveals neurons in the cerebral cortex of a mouse with <70-nanometer resolution. Dendritic spines and their subtle changes can be observed at their relevant scales over extended periods of time.
Issue Date
2012
Journal
Science 
ISSN
0036-8075
Language
English

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