Oncotarget

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  • 2022 | Journal Article
    ​ ​Addendum: Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition​
    Kemper, M.; Evers, G.; Schulze, A. B.; Sperveslage, J.; Schülke, C.; Lenz, G. & Herold, T. et al.​ (2022) 
    Oncotarget, 13(1) pp. 1216​-1216​.​ DOI: https://doi.org/10.18632/oncotarget.28293 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition​
    Kemper, M.; Evers, G.; Schulze, A. B.; Sperveslage, J.; Schülke, C.; Lenz, G. & Herold, T. et al.​ (2021) 
    Oncotarget, 12(19) pp. 1946​-1952​.​ DOI: https://doi.org/10.18632/oncotarget.28062 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Survival after resection of brain metastases with white light microscopy versus fluorescence-guidance: A matched cohort analysis of the Metastasys study data​
    Hussein, A.; Rohde, V.; Wolfert, C.; Hernandez-Duran, S.; Fiss, I.; Bleckmann, A. & Freer, A. B. et al.​ (2020) 
    Oncotarget, 11(32) pp. 3026​-3034​.​ DOI: https://doi.org/10.18632/oncotarget.27688 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Expression profiling on subclasses of primary parotid gland carcinomas​
    Meinrath, J.; Haak, A.; Igci, N.; Dalvi, P.; Arolt, C.; Meemboor, S. & Siebolts, U. et al.​ (2020) 
    Oncotarget, 11(45) pp. 4123​-4137​.​ DOI: https://doi.org/10.18632/oncotarget.27797 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development​
    Li, Y.; Xiao, X.; Bossé, Y.; Gorlova, O.; Gorlov, I.; Han, Y. & Byun, J. et al.​ (2019) 
    Oncotarget, 10(19) pp. 1760​-1774​.​ DOI: https://doi.org/10.18632/oncotarget.26678 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​FGFR3 mRNA overexpression defines a subset of oligometastatic colorectal cancers with worse prognosis​
    Fromme, J. E.; Schmitz, K.; Wachter, A.; Grzelinski, M.; Zielinski, D.; Koppel, C. & Conradi, L.-C. et al.​ (2018) 
    Oncotarget, 9(63) pp. 32204​-32218​.​ DOI: https://doi.org/10.18632/oncotarget.25941 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Chemical exchange saturation transfer MRI serves as predictor of early progression in glioblastoma patients​
    Regnery, S.; Adeberg, S.; Dreher, C.; Oberhollenzer, J.; Meissner, J.-E.; Goerke, S. & Windschuh, J. et al.​ (2018) 
    Oncotarget, 9(47) pp. 28772​-28783​.​ DOI: https://doi.org/10.18632/oncotarget.25594 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFRmut NSCLC in diagnosis, follow-up and treatment​
    Lüke, F.; Blazquez, R.; Yamaci, R. F.; Lu, X.; Pregler, B.; Hannus, S. & Menhart, K. et al.​ (2018) 
    Oncotarget, 9(27) pp. 18844-18857​.​ DOI: https://doi.org/10.18632/oncotarget.24787 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | Research Paper
    ​ ​Adenosine A2A receptor ligand recognition and signaling is blocked by A2B receptors​
    Hinz, S.; Navarro, G.; Borroto-Escuela, D.; Seibt, B. F; Ammon, Y.-C.; de Filippo, E. & Danish, A. et al.​ (2018) 
    Oncotarget, 9(17) pp. 13593​-13611​.​ DOI: https://doi.org/10.18632/oncotarget.24423 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​Testosterone metabolites inhibit proliferation of castration- and therapy-resistant prostate cancer​
    Bremmer, F.; Jarry, H.; Unterkircher, V.; Kaulfuss, S.; Burfeind, P.; Radzun, H.-J. & Ströbel, P. et al.​ (2018) 
    Oncotarget, 9(24) pp. 16951​-16961​.​ DOI: https://doi.org/10.18632/oncotarget.24763 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​The glucocorticoid receptor in recipient cells keeps cytokine secretion in acute graft-versus-host disease at bay​
    Baake, T.; Jörß, K.; Suennemann, J.; Roßmann, L.; Bohnenberger, H.; Tuckermann, J. P. & Reichardt, H. M. et al.​ (2018) 
    Oncotarget, 9(21) pp. 15437​-15450​.​ DOI: https://doi.org/10.18632/oncotarget.24602 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Riluzole: a potential therapeutic intervention in human brain tumor stem-like cells​
    Sperling, S. ; Aung, T. ; Martin, S. ; Rohde, V.   & Ninkovic, M. ​ (2017) 
    Oncotarget, 8(57) art. 96697​.​ DOI: https://doi.org/10.18632/oncotarget.18043 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Low-dose photon irradiation induces invasiveness through the SDF-1α/CXCR4 pathway in malignant mesothelioma cells​
    Yamauchi, Y.; Safi, S.; Orschiedt, L.; Gardyan, A.; Brons, S.; Rieber, J. & Nicolay, N. H et al.​ (2017) 
    Oncotarget, 8(40) pp. 68001​-68011​.​ DOI: https://doi.org/10.18632/oncotarget.19134 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | 
    ​ ​The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner​
    Wiese, M. ; Walther, N. ; Diederichs, C. ; Schill, F. ; Monecke, S. ; Salinas, G.   & Sturm, D. et al.​ (2017) 
    Oncotarget, 8(16) pp. 27300​-27313​.​ DOI: https://doi.org/10.18632/oncotarget.15934 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | Research Paper
    ​ ​MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrences-implications for immunotherapy​
    Laban, S.; Giebel, G.; Klümper, N.; Schröck, A.; Doescher, J.; Spagnoli, G. & Thierauf, J. et al.​ (2017) 
    Oncotarget, 8(9) pp. 14719​-14735​.​ DOI: https://doi.org/10.18632/oncotarget.14830 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Subclinical involvement of the liver is associated with prognosis in treatment naïve cancer patients​
    Pavo, N.; Raderer, M.; Goliasch, G.; Wurm, R.; Strunk, G.; Cho, A. & Novak, J. F. et al.​ (2017) 
    Oncotarget, 8(46) pp. 81250​-81260​.​ DOI: https://doi.org/10.18632/oncotarget.v8i46 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Identification of the histone lysine demethylase KDM4A/JMJD2A as a novel epigenetic target in M1 macrophage polarization induced by oxidized LDL​
    Wang, X.; Wang, S.; Yao, G.; Yu, D.; Chen, K.; Tong, Q. & Ye, L. et al.​ (2017) 
    Oncotarget, 8(70) pp. 114442​-114456​.​ DOI: https://doi.org/10.18632/oncotarget.v8i70 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Splice variants of the endonucleases XPF and XPG contain residual DNA repair capabilities and could be a valuable tool for personalized medicine​
    Lehmann, J.; Schubert, S.; Seebode, C.; Apel, A.; Ohlenbusch, A. & Emmert, S.​ (2017) 
    Oncotarget, 9(1) pp. 1012​-1027​.​ DOI: https://doi.org/10.18632/oncotarget.23105 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​High-grade glioma in very young children: a rare and particular patient population​
    El-Ayadi, M.; Ansari, M.; Sturm, D.; Gielen, G. H.; Warmuth-Metz, M.; Kramm, C. M. & von Bueren, A. O.​ (2017) 
    Oncotarget, 8(38) pp. 64564​-64578​.​ DOI: https://doi.org/10.18632/oncotarget.18478 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​LEF1 reduces tumor progression and induces myodifferentiation in a subset of rhabdomyosarcoma​
    Draeger, J.; Simon-Keller, K.; Pukrop, T.; Klemm, F.; Wilting, J.; Sticht, C. & Dittmann, K. et al.​ (2017) 
    Oncotarget, 8(2) pp. 3259​-3273​.​ DOI: https://doi.org/10.18632/oncotarget.13887 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article
    ​ ​Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer​
    Kozlova, N.; Wottawa, M.; Katschinski, D. M.; Kristiansen, G. & Kietzmann, T.​ (2017) 
    Oncotarget, 8(6) pp. 9885​-9898​.​ DOI: https://doi.org/10.18632/oncotarget.14241 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​Prospects of estrogen receptor beta activation in the treatment of castration-resistant prostate cancer​
    Gehrig, J. ; Kaulfuss, S.; Jarry, H.; Bremmer, F.; Stettner, M.; Burfeind, P. & Thelen, P.​ (2017) 
    Oncotarget, 8(21) pp. 34971​-34979​.​ DOI: https://doi.org/10.18632/oncotarget.16496 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article
    ​ ​PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression​
    Hohensee, I.; Chuang, H.-N.; Grottke, A.; Werner, S.; Schulte, A.; Horn, S. & Lamszus, K. et al.​ (2017) 
    Oncotarget, 8(4) pp. 6155​-6168​.​ DOI: https://doi.org/10.18632/oncotarget.14047 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​Proposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential pre-MDS conditions​
    Valent, P.; Orazi, A.; Steensma, D. P.; Ebert, B. L.; Haase, D.; Malcovati, L. & van de Loosdrecht, A. A. et al.​ (2017) 
    Oncotarget, 8(43) pp. 73483​-73500​.​ DOI: https://doi.org/10.18632/oncotarget.19008 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | 
    ​ ​Increased cFLIP expression in thymic epithelial tumors blocks autophagy via NF-κB signalling​
    Belharazem, D.; Grass, A.; Paul, C.; Vitacolonna, M.; Schalke, B.; Rieker, R. J. & Körner, D. et al.​ (2017) 
    Oncotarget, 8(52) pp. 89580​-89594​.​ DOI: https://doi.org/10.18632/oncotarget.15929 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper
    ​ ​Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade​
    Schmidt, M.; Mock, A.; Jungk, C.; Sahm, F.; Ull, A. T.; Warta, R. & Lamszus, K. et al.​ (2016) 
    Oncotarget, 7(12) pp. 14551​-14568​.​ DOI: https://doi.org/10.18632/oncotarget.7396 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article
    ​ ​Progress in CSF biomarker discovery in sCJD​
    Llorens, F.; Schmitz, M. & Zerr, I.​ (2016) 
    Oncotarget, 8(4) pp. 5666​-5667​.​ DOI: https://doi.org/10.18632/oncotarget.13998 
    ​Details  DOI 
  • 2016 | Journal Article | 
    ​ ​Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data​
    Schrader, A.; Meyer, K.; Walther, N.; Stolz, A.; Feist, M. ; Hand, E. & von Bonin, F. et al.​ (2016) 
    Oncotarget, 7(30) pp. 47061​-47081​.​ DOI: https://doi.org/10.18632/oncotarget.9219 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​The role of Pygo2 for Wnt/beta-catenin signaling activity during intestinal tumor initiation and progression​
    Talla, S. B. & Brembeck, F. H.​ (2016) 
    Oncotarget, 7(49) pp. 80612​-80632​.​ DOI: https://doi.org/10.18632/oncotarget.13016 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Th17 cytokine differentiation and loss of plasticity after SOCS1 inactivation in a cutaneous T-cell lymphoma​
    Ehrentraut, S.; Schneider, B.; Nagel, S.; Pommerenke, C.; Quentmeier, H.; Geffers, R. & Feist, M. et al.​ (2016) 
    Oncotarget, 7(23) pp. 34201​-34216​.​ DOI: https://doi.org/10.18632/oncotarget.9077 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​LTR12 promoter activation in a broad range of human tumor cells by HDAC inhibition​
    Kronung, S. K.; Beyer, U.; Chiaramonte, M. L.; Dolfini, D.; Mantovani, R. & Dobbelstein, M. ​ (2016) 
    Oncotarget, 7(23) pp. 33484​-33497​.​ DOI: https://doi.org/10.18632/oncotarget.9255 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Characterization of the novel indolylmaleimides' PDA-66 and PDA-377 effect on canine lymphoma cells​
    Liu, W.; Beck, J.; Schmidt, L. C.; Roolf, C.; Pews-Davtyan, A.; Ruetgen, B. C. & Hammer, S. et al.​ (2016) 
    Oncotarget, 7(23) pp. 35379​-35389​.​ DOI: https://doi.org/10.18632/oncotarget.9297 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy​
    Roedel, F.; Martin, D. M. A.; Helmke, C.; Balermpas, P.; Fokas, E.; Wieland, U. & Rave-Fraenk, M. et al.​ (2016) 
    Oncotarget, 7(33) pp. 53339​-53349​.​ DOI: https://doi.org/10.18632/oncotarget.10801 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Deletion of 14-3-3 sigma sensitizes mice to DMBA/TPA-induced papillomatosis​
    Winter, M.; Lodygin, D.; Verdoodt, B. & Hermeking, H.​ (2016) 
    Oncotarget, 7(30) pp. 46862​-46870​.​ DOI: https://doi.org/10.18632/oncotarget.10478 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​T cell abundance in blood predicts acute organ toxicity in chemoradiotherapy for head and neck cancer​
    Beschel, L. M.; Leu, M.; Reichardt, S. D.; Rave-Fraenk, M.; Schirmer, M. A.; Stadelmann, C.   & Canis, M. et al.​ (2016) 
    Oncotarget, 7(40) pp. 65902​-65915​.​ DOI: https://doi.org/10.18632/oncotarget.11677 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Twist1 induces distinct cell states depending on TGFBR1-activation​
    Dragoi, D.; Krattenmacher, A.; Mishra, V. K.; Schmidt, J. M.; Kloos, U. J.; Meixner, L. K. & Hauck, S. M. et al.​ (2016) 
    Oncotarget, 7(21) pp. 30396​-30407​.​ DOI: https://doi.org/10.18632/oncotarget.8878 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo​
    Wegwitz, F.; Lenfert, E.; Gerstel, D.; von Ehrenstein, L.; Einhoff, J.; Schmidt, G. & Logsdon, M. et al.​ (2016) 
    Oncotarget, 7(39) pp. 63730​-63746​.​ DOI: https://doi.org/10.18632/oncotarget.11650 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity​
    Sriraman, A.; Radovanovic, M.; Wienken, M.; Najafova, Z.; Li, Y. & Dobbelstein, M. ​ (2016) 
    Oncotarget, 7(22) pp. 31623​-31638​.​ DOI: https://doi.org/10.18632/oncotarget.9302 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Usp22 deficiency impairs intestinal epithelial lineage specification in vivo.​
    Kosinsky, R. L.; Wegwitz, F.; Hellbach, N.; Dobbelstein, M. ; Mansouri, A.; Vogel, T. & Begus-Nahrmann, Y. et al.​ (2015) 
    Oncotarget, 6(35) pp. 37906​-37918​.​ DOI: https://doi.org/10.18632/oncotarget.5412 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitro.​
    Künstlinger, H.; Fassunke, J.; Schildhaus, H.-U.; Brors, B.; Heydt, C.; Ihle, M. A. & Mechtersheimer, G. et al.​ (2015) 
    Oncotarget, 6(24) pp. 20215​-20130​.​ DOI: https://doi.org/10.18632/oncotarget.4046 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​Anti-CSF-1 treatment is effective to prevent carcinoma invasion induced by monocyte-derived cells but scarcely by microglia.​
    Rietkötter, E.; Bleckmann, A.; Bayerlová, M.; Menck, K.; Chuang, H.-N.; Wenske, B. & Schwartz, H. et al.​ (2015) 
    Oncotarget, 6(17) pp. 15482​-15493​.​ DOI: https://doi.org/10.18632/oncotarget.3855 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​Leupaxin stimulates adhesion and migration of prostate cancer cells through modulation of the phosphorylation status of the actin-binding protein caldesmon.​
    Dierks, S.; von Hardenberg, S.; Schmidt, T.; Bremmer, F.; Burfeind, P. & Kaulfuß, S.​ (2015) 
    Oncotarget, 6(15) pp. 13591​-13606​.​ DOI: https://doi.org/10.18632/oncotarget.3792 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair.​
    Srinivas, U. S.; Dyczkowski, J.; Beißbarth, T. ; Gaedcke, J. ; Mansour, W. Y.; Borgmann, K. & Dobbelstein, M. ​ (2015) 
    Oncotarget, 6(14) pp. 12574​-12586​.​ DOI: https://doi.org/10.18632/oncotarget.3728 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​ROS1 rearrangements in lung adenocarcinoma: prognostic impact, therapeutic options and genetic variability.​
    Scheffler, M.; Schultheis, A.; Teixido, C.; Michels, S.; Morales-Espinosa, D.; Viteri, S. & Hartmann, W. et al.​ (2015) 
    Oncotarget, 6(12) pp. 10577​-10585​.​ DOI: https://doi.org/10.18632/oncotarget.3387 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma.​
    Graab, U.; Hahn, H. & Fulda, S.​ (2015) 
    Oncotarget, 6(11) pp. 8722​-8735​.​ DOI: https://doi.org/10.18632/oncotarget.2726 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy.​
    Nitzki, F.; Tolosa, E. J.; Cuvelier, N.; Frommhold, A.; Salinas-Riester, G.; Johnsen, S. A. & Fernandez-Zapico, M. E. et al.​ (2015) 
    Oncotarget, 6(11) pp. 9113​-9124​.​ DOI: https://doi.org/10.18632/oncotarget.3272 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​c-myc copy number gain is a powerful prognosticator of disease outcome in cervical dysplasia.​
    Kübler, K.; Heinenberg, S.; Rudlowski, C.; Keyver-Paik, M.-D.; Abramian, A.; Merkelbach-Bruse, S. & Büttner, R. et al.​ (2015) 
    Oncotarget, 6(2) pp. 825​-835​.​ DOI: https://doi.org/10.18632/oncotarget.2706 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article
    ​ ​HER-2 and HER-3 expression in liver metastases of patients with colorectal cancer​
    Styczen, H.; Nagelmeier, I.; Beißbarth, T. ; Nietert, M. M. ; Homayounfar, K. ; Sprenger, T.   & Boczek, U. et al.​ (2015) 
    Oncotarget, 6(17) pp. 15065​-15076​.​
    ​Details  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells​
    Schmidt, F.; Kunze, M.; Loock, A.-C. & Dobbelstein, M. ​ (2015) 
    Oncotarget, 6(2) pp. 617​-632​.​
    ​Details  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​H4K12ac is regulated by estrogen receptor-alpha and is associated with BRD4 function and inducible transcription​
    Nagarajan, S. ; Benito-Garagorri, E.; Fischer, A.   & Johnsen, S. A. ​ (2015) 
    Oncotarget, 6(9) pp. 7305​-7317​.​ DOI: https://doi.org/10.18632/oncotarget.3439 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​TRAIL-R2 promotes skeletal metastasis in a breast cancer xenograft mouse model​
    Fritsche, H.; Heilmann, T.; Tower, R. J.; Hauser, C.; Au, A. von; El-Sheikh, D. & Campbell, G. M. et al.​ (2015) 
    Oncotarget, 6(11) pp. 9502​-9516​.​ DOI: https://doi.org/10.18632/oncotarget.3321 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitors​
    Li, Y.; Saini, P.; Sriraman, A. & Dobbelstein, M. ​ (2015) 
    Oncotarget, 6(32) pp. 32339​-32352​.​ DOI: https://doi.org/10.18632/oncotarget.5891 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress.​
    Saini, P.; Li, Y. & Dobbelstein, M. ​ (2015) 
    Oncotarget, 6(15) pp. 13072​-13087​.​ DOI: https://doi.org/10.18632/oncotarget.3865 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper | 
    ​ ​The indirect NMDAR inhibitor flupirtine induces sustained post-ischemic recovery, neuroprotection and angioneurogenesis​
    Jaeger, H. M.; Pehlke, J. R.; Kaltwasser, B.; Kilic, E. ; Bähr, M. ; Hermann, D. M. & Doeppner, T. R. ​ (2015) 
    Oncotarget, 6(16) pp. 14033​-14044​.​ DOI: https://doi.org/10.18632/oncotarget.4226 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Role of N-cadherin in proliferation, migration, and invasion of germ cell tumours​
    Bremmer, F.; Schallenberg, S.; Jarry, H.; Kueffer, S.; Kaulfuss, S.; Burfeind, P. & Strauss, A. et al.​ (2015) 
    Oncotarget, 6(32) pp. 33426​-33437​.​ DOI: https://doi.org/10.18632/oncotarget.5288 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​The metastatic infiltration at the metastasis/brain parenchyma-interface is very heterogeneous and has a significant impact on survival in a prospective study​
    Siam, L.; Bleckmann, A.; Chaung, H.-N.; Mohr, A.; Klemm, F.; Barrantes-Freer, A. & Blazquez, R. et al.​ (2015) 
    Oncotarget, 6(30) pp. 29254​-29267​.​ DOI: https://doi.org/10.18632/oncotarget.4201 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​Higher mortality and impaired elimination of bacteria in aged mice after intracerebral infection with E. coli are associated with an age-related decline of microglia and macrophage functions.​
    Schütze, S.; Ribes, S.; Kaufmann, A.; Manig, A.; Scheffel, J.; Redlich, S. & Bunkowski, S. et al.​ (2014) 
    Oncotarget, 5(24) pp. 12573​-12592​.​
    ​Details  PMID  PMC 
  • 2014 | Journal Article | 
    ​ ​Selective targeting of KRAS-mutant cells by miR-126 through repression of multiple genes essential for the survival of KRAS-mutant cells.​
    Hara, T.; Jones, M. F.; Subramanian, M.; Li, X. L.; Ou, O.; Zhu, Y. & Yang, Y. et al.​ (2014) 
    Oncotarget, 5(17) pp. 7635​-7650​.​
    ​Details  PMID  PMC 
  • 2014 | Journal Article | 
    ​ ​The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis.​
    Zatula, N.; Wiese, M.; Bunzendahl, J.; Birchmeier, W.; Perske, C.; Bleckmann, A. & Brembeck, F. H.​ (2014) 
    Oncotarget, 5(16) pp. 6770​-6787​.​ DOI: https://doi.org/10.18632/oncotarget.2252 
    ​Details  DOI  PMID  PMC 
  • 2014 | Journal Article | 
    ​ ​Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention.​
    Davis, N. M.; Sokolosky, M.; Stadelman, K.; Abrams, S. L.; Libra, M.; Candido, S. & Nicoletti, F. et al.​ (2014) 
    Oncotarget, 5(13) pp. 4603​-4650​.​
    ​Details  PMID  PMC 
  • 2014 | Journal Article | 
    ​ ​GSK-3 as potential target for therapeutic intervention in cancer.​
    McCubrey, J. A.; Steelman, L. S.; Bertrand, F. E.; Davis, N. M.; Sokolosky, M.; Abrams, S. L. & Montalto, G. et al.​ (2014) 
    Oncotarget, 5(10) pp. 2881​-2911​.​ DOI: https://doi.org/10.18632/oncotarget.2037 
    ​Details  DOI  PMID  PMC 
  • 2014 | Review
    ​ ​Epigenetic plasticity: A central regulator of epithelial-to-mesenchymal transition in cancer​
    Bedi, U.; Mishra, V. K.; Wasilewski, D.; Johnsen, S. A.& Scheel, C. H.​ (2014)
    Oncotarget, 5​(8) pp. 2016​-2029​.​
    Impact Journals Llc. DOI: https://doi.org/10.18632/oncotarget.1875 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells​
    Schmidt, F.; Kunze, M.; Loock, A.-C. & Dobbelstein, M. ​ (2014) 
    Oncotarget, 6(2) pp. 617​-632​.​ DOI: https://doi.org/10.18632/oncotarget.2710 
    ​Details  DOI 
  • 2014 | Journal Article | 
    ​ ​Identification of a DNA methylation signature to predict disease-free survival in locally advanced rectal cancer​
    Gaedcke, J.; Leha, A.; Claus, R.; Weichenhan, D.; Jung, K.; Kitz, J. & Grade, M. et al.​ (2014) 
    Oncotarget, 5(18) pp. 8123​-8135​.​ DOI: https://doi.org/10.18632/oncotarget.2347 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation​
    Keitel, U.; Scheel, A.; Thomale, J.; Halpape, R.; Kaulfuß, S.; Scheel, C. & Dobbelstein, M. ​ (2014) 
    Oncotarget, 5(23) pp. 11778​-11791​.​ DOI: https://doi.org/10.18632/oncotarget.2634 
    ​Details  DOI  PMID  PMC 
  • 2013 | Journal Article | 
    ​ ​Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5.​
    Exertier, P.; Javerzat, S.; Wang, B.; Franco, M.; Herbert, J.; Platonova, N. & Winandy, M. et al.​ (2013) 
    Oncotarget, 4(12) pp. 2302​-2316​.​
    ​Details  PMID  PMC 
  • 2013 | Journal Article | 
    ​ ​Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles.​
    Menck, K.; Klemm, F.; Gross, J. C.; Pukrop, T.; Wenzel, D. & Binder, C.​ (2013) 
    Oncotarget, 4(11) pp. 2057​-2066​.​
    ​Details  PMID  PMC 
  • 2013 | Journal Article | 
    ​ ​Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion.​
    Rietkötter, E.; Menck, K.; Bleckmann, A.; Farhat, K.; Schaffrinski, M.; Schulz, M. & Hanisch, U.-K. et al.​ (2013) 
    Oncotarget, 4(9) pp. 1449​-1460​.​
    ​Details  PMID  PMC 
  • 2013 | Journal Article | 
    ​ ​SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients.​
    Schif, B.; Lennerz, J. K.; Kohler, C. W.; Bentink, S.; Kreuz, M.; Melzner, I. & Ritz, O. et al.​ (2013) 
    Oncotarget, 4(1) pp. 35​-47​.​
    ​Details  PMID  PMC 
  • 2013 | Journal Article | 
    ​ ​Blockade of the PDGFR family together with SRC leads to diminished proliferation of colorectal cancer cells​
    Kaulfuß, S.; Seemann, H.; Kampe, R.; Meyer, J.; Dressel, R.; König, B. & Scharf, J.-G. et al.​ (2013) 
    Oncotarget, 4 7 pp. 1037​-1049​.​ DOI: https://doi.org/10.18632/oncotarget.1085 
    ​Details  DOI  PMID  PMC 
  • 2012 | Review
    ​ ​Advances in Targeting Signal Transduction Pathways​
    McCubrey, J. A.; Steelman, L. S.; Chappell, W. H.; Sun, L.; Davis, N. M.; Abrams, S. L.& Franklin, R. A. et al.​ (2012)
    Oncotarget, 3​(12) pp. 1505​-1521​.​
    Impact Journals Llc.
    ​Details  PMID  PMC  WoS 
  • 2012 | Review
    ​ ​Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance​
    McCubrey, J. A.; Steelman, L. S.; Chappell, W. H.; Abrams, S. L.; Franklin, R. A.; Montalto, G.& Cervello, M. et al.​ (2012)
    Oncotarget, 3​(10) pp. 1068​-1111​.​
    Impact Journals Llc.
    ​Details  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response.​
    McCubrey, J. A.; Steelman, L. S.; Chappell, W. H.; Abrams, S. L.; Montalto, G.; Cervello, M. & Nicoletti, F. et al.​ (2012) 
    Oncotarget, 3(9) pp. 954​-987​.​
    ​Details  PMID  PMC  WoS 
  • 2011 | Review
    ​ ​Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health​
    Chappell, W. H.; Steelman, L. S.; Long, J. M.; Kempf, C. R.; Abrams, S. L.; Franklin, R. A.& Baesecke, J. et al.​ (2011)
    Oncotarget, 2​(3) pp. 135​-164​.​
    Impact Journals Llc.
    ​Details  PMID  PMC  WoS 

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