Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE)

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DZNE
 

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  • 2023 | Journal Article | 
    ​ ​Müller SJ, Khadhraoui E, Hansen N, Jamous A, Langer P, Wiltfang J, et al. ​Brainstem atrophy in dementia with Lewy bodies compared with progressive supranuclear palsy and Parkinson’s disease on MRI​. ​​BMC Neurology. ​2023;​23​(1). ​doi:10.1186/s12883-023-03151-4. 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​Schmitz M, Candelise N, Canaslan S, Altmeppen HC, Matschke J, Glatzel M, et al. ​α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies​. ​​Translational Neurodegeneration. ​2023;​12​(1). ​doi:10.1186/s40035-023-00342-4. 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​Heinzinger N, Maass A, Berron D, Yakupov R, Peters O, Fiebach J, et al. ​Exploring the ATN classification system using brain morphology​. ​​Alzheimer's Research & Therapy. ​2023;​15​(1). ​doi:10.1186/s13195-023-01185-x. 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​Yildirim Z, Delen F, Berron D, Baumeister H, Ziegler G, Schütze H, et al. ​Brain reserve contributes to distinguishing preclinical Alzheimer’s stages 1 and 2​. ​​Alzheimer's Research & Therapy. ​2023;​15​(1). ​doi:10.1186/s13195-023-01187-9. 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Klafki, Hans-W., Vogelgsang J, Manuilova E, Bauer C, Jethwa A, Esselmann H, et al. ​Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation​. ​​Alzheimer's Research & Therapy. ​2022;​14​(1). ​doi:10.1186/s13195-022-01071-y. 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Babu M, Favretto F, Rankovic M, Zweckstetter M. ​Peptidyl Prolyl Isomerase A Modulates the Liquid–Liquid Phase Separation of Proline-Rich IDPs​. ​​Journal of the American Chemical Society. ​2022;. ​doi:10.1021/jacs.2c07149. 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Hansen N, Rauter C, Wiltfang J. ​Blutbasierte Biomarker zur Optimierung der Früh- und Differentialdiagnostik der Alzheimer-Demenz​. ​​Fortschritte der Neurologie · Psychiatrie. ​2022;​90​(07/08):​​326​-335​. ​doi:10.1055/a-1839-6237. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Polcher A, Wolfsgruber S, Peters O, Frölich L, Wiltfang J, Kornhuber J, et al. ​A Comparison of Operational Definitions for Mild Cognitive Impairment​. ​​Journal of Alzheimer's Disease. ​2022;​88​(4):​​1663​-1678​. ​doi:10.3233/JAD-215548. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Ibáñez de Opakua A, Geraets JA, Frieg B, Dienemann C, Savastano A, Rankovic M, et al. ​Molecular interactions of FG nucleoporin repeats at high resolution​. ​​Nature Chemistry. ​2022;. ​doi:10.1038/s41557-022-01035-7. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Böttcher A, Zarucha A, Köbe T, Gaubert M, Höppner A, Altenstein S, et al. ​Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults​. ​​Frontiers in Psychology. ​2022;​13​. ​doi:10.3389/fpsyg.2022.945709. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Sang D, Shu T, Pantoja CF, Ibáñez de Opakua A, Zweckstetter M, Holt LJ. ​Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding​. ​​Molecular Cell. ​2022;. ​doi:10.1016/j.molcel.2022.08.016. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Oeckl P, Anderl‐Straub S, Danek A, Diehl‐Schmid J, Fassbender K, Fliessbach K, et al. ​Relationship of serum beta‐synuclein with blood biomarkers and brain atrophy​. ​​Alzheimer's & Dementia. ​2022;. ​doi:10.1002/alz.12790. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Zachrdla M, Savastano A, Ibáñez de Opakua A, Cima‐Omori M, Zweckstetter M. ​Contributions of the N‐terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA‐induced phase separation​. ​​Protein Science. ​2022;​31​(9). ​doi:10.1002/pro.4409. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Frieg B, Geraets JA, Strohäker T, Dienemann C, Mavroeidi P, Jung BC, et al. ​Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein​. ​​Communications Biology. ​2022;​5​(1). ​doi:10.1038/s42003-022-03948-y. 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Chakraborty P, Zweckstetter M. ​Phase separation of the microtubule-associated protein tau​. ​​Essays in Biochemistry. ​2022;. ​doi:10.1042/EBC20220066. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, et al. ​Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers​. ​​Acta Neuropathologica. ​2022;. ​doi:10.1007/s00401-022-02454-z. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Töpfer FM, Barbieri R, Sexton CM, Wang X, Soch J, Bogler C, et al. ​Psychophysics and computational modeling of feature-continuous motion perception​. ​​Journal of Vision. ​2022;​22​(11):​​16​. ​doi:10.1167/jov.22.11.16. 
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  • 2022 | Journal Article | 
    ​ ​Daskalaki M, Drummer C, Behr R, Heistermann M. ​The use of alfaxalone for short-term anesthesia can confound serum progesterone measurements in the common marmoset: a case report​. ​​Primate Biology. ​2022;​9​(2):​​23​-28​. ​doi:10.5194/pb-9-23-2022. 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Kleineidam L, Wagner M, Guski J, Wolfsgruber S, Miebach L, Bickel H, et al. ​Disentangling the relationship of subjective cognitive decline and depressive symptoms in the development of cognitive decline and dementia​. ​​Alzheimer's & Dementia. ​2022;. ​doi:10.1002/alz.12785. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Shvachiy L, Amaro-Leal Â, Outeiro TF, Rocha I, Geraldes V. ​From Molecular to Functional Effects of Different Environmental Lead Exposure Paradigms​. ​​Biology. ​2022;​11​(8):​​1164​. ​doi:10.3390/biology11081164. 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | 
    ​ ​Schmachtenberg T, Monsees J, Thyrian JR. ​Structures for the care of people with dementia: a European comparison​. ​​BMC Health Services Research. ​2022;​22​(1):​​1372​. ​doi:10.1186/s12913-022-08715-7. 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | 
    ​ ​Koss DJ, Erskine D, Porter A, Palmoski P, Menon H, Todd OGJ, et al. ​Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies​. ​​Acta Neuropathologica Communications. ​2022;​10​(1). ​doi:10.1186/s40478-022-01403-x. 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | 
    ​ ​Hansen N, Hirschel S, Teegen B, Wiltfang J, Malchow B. ​Preserved visuoconstruction in patients with Alzheimer's pathology and anti-neural autoantibodies: A case control study​. ​​Frontiers in Dementia. ​2022;​1​. ​doi:10.3389/frdem.2022.975851. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Juhl AL, Grenzer IM, Teegen B, Wiltfang J, Fitzner D, Hansen N. ​Biomarkers of neurodegeneration in neural autoantibody-associated psychiatric syndromes: A retrospective cohort study​. ​​Journal of translational autoimmunity. ​2022;​5​. ​doi:10.1016/j.jtauto.2022.100169. 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Besse M, Signerski-Krieger J, Wiltfang J, Bartels C, Belz M. ​One year of digital teaching in psychiatry as a response to the COVID-19 pandemic: Knowledge gain and content evaluation of medical students for two summer semesters in 2020 and 2021​. ​​PLOS ONE. ​2022;​17​(10). ​doi:10.1371/journal.pone.0276660. 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Brás IC, Khani MH, Vasili E, Möbius W, Riedel D, Parfentev I, et al. ​Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity​. ​​Journal of Parkinson's Disease. ​2022;:​​1​-26​. ​doi:10.3233/JPD-223516. 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Schaper S, Meyer-Rötz SH, Bartels C, Wiltfang J, Rödig T, Schott BH, et al. ​Dental Care of Patients With Dementia: A Survey on Practice Equipment, Training, and Dental Treatment​. ​​Frontiers in oral health. ​2021;​2​:​​682139​. ​doi:10.3389/froh.2021.682139. 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Jordan W, Dobrowolny H, Bahn S, Bernstein, Hans-Gert, Brigadski T, Frodl T, et al. ​Oxidative stress in drug-naïve first episode patients with schizophrenia and major depression: ​effects of disease acuity and potential confounders​. ​​European Archives of Psychiatry and Clinical Neuroscience. ​2018;​268​(2):​​129​-143​. ​doi:10.1007/s00406-016-0749-7. 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Hüttenrauch M, Ogorek I, Klafki H, Otto M, Stadelmann C, Weggen S, et al. ​Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microglia​. ​​Acta Neuropathologica Communications. ​2018;​6​(1). ​doi:10.1186/s40478-018-0612-3. 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Tolö J, Taschenberger G, Leite K, Stahlberg MA, Spehlbrink G, Kues J, et al. ​Pathophysiological Consequences of Neuronal α-Synuclein Overexpression: Impacts on Ion Homeostasis, Stress Signaling, Mitochondrial Integrity, and Electrical Activity​. ​​Frontiers in Molecular Neuroscience. ​2018;​11​. ​doi:10.3389/fnmol.2018.00049. 
    ​Details  DOI 
  • 2018 | Journal Article | Overview | 
    ​ ​Roser, Anna-Elisa, Caldi Gomes L, Schünemann J, Maass F, Lingor P. ​Circulating miRNAs as Diagnostic Biomarkers for Parkinson’s Disease​. ​​Frontiers in Neuroscience. ​2018;​12​. ​doi:10.3389/fnins.2018.00625. 
    ​Details  DOI  arXiv 
  • 2018 | Journal Article | 
    ​ ​Shahpasand-Kroner H, Klafki, Hans-W., Bauer C, Schuchhardt J, Hüttenrauch M, Stazi M, et al. ​A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s disease​. ​​Alzheimer's Research & Therapy. ​2018;​10​(1). ​doi:10.1186/s13195-018-0448-x. 
    ​Details  DOI 
  • 2018 | Journal Article | Research Paper | 
    ​ ​Mandad S, Rahman, Raza-Ur, Centeno TP, Vidal RO, Wildhagen H, Rammner B, et al. ​The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain​. ​​Scientific Reports. ​2018;​8​(1). ​doi:10.1038/s41598-018-35277-8. 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​Weise SC, Arumugam G, Villarreal A, Videm P, Heidrich S, Nebel N, et al. ​FOXG1 Regulates PRKAR2B Transcriptionally and Posttranscriptionally via miR200 in the Adult Hippocampus​. ​​Molecular Neurobiology. ​2018;:​​1​-14​. ​doi:10.1007/s12035-018-1444-7. 
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  • 2018 | Journal Article | 
    ​ ​Oroz J, Chang BJ, Wysoczanski P, Lee, Chung-Tien, Pérez-Lara Á, Chakraborty P, et al. ​Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex​. ​​Nature Communications. ​2018;​9​(1). ​doi:10.1038/s41467-018-06880-0. 
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  • 2018 | Journal Article | Research Paper | 
    ​ ​Fornasiero EF, Mandad S, Wildhagen H, Alevra M, Rammner B, Keihani S, et al. ​Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions.​. ​​Nature Communications. ​2018;​9​(1). ​doi:10.1038/s41467-018-06519-0. 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article | 
    ​ ​Belz M, Rehling N, Schmidt U, Wiltfang J, Kis B, Wolff-Menzler C. ​Bacterial infections among patients with psychiatric disorders: Relation with hospital stay, age, and psychiatric diagnoses​. ​​PLOS ONE. ​2018;​13​(12). ​doi:10.1371/journal.pone.0208458. 
    ​Details  DOI  PMID  PMC 

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